Functional neuroimaging in child psychiatry
Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes knowledge of neurodevelopment and brain maturation. However, much of human brain science is based on inferences from animal work and indirect neuroc...
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| Published in | Current psychiatry reports Vol. 2; no. 2; pp. 124 - 130 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Springer Nature B.V
01.04.2000
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1523-3812 1535-1645 |
| DOI | 10.1007/s11920-000-0056-9 |
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| Abstract | Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes knowledge of neurodevelopment and brain maturation. However, much of human brain science is based on inferences from animal work and indirect neurochemical measures from body fluids. Neuroimaging can examine brain development directly in humans. The benefits can be enormous for learning how and when to intervene to prevent or treat a disorder. These unprecedented potential gains are countered by complex and difficult ethical issues. Technical advances can reduce ethical concerns by minimizing risks. They also promise to enhance the sensitivity and specificity of the measures (eg, by improving spatial and temporal resolution). Judiciously designed investigations will permit the testing of a priori hypotheses built on rational models of neuropathology. Finally, it is the integration of scientific knowledge across the various fields of neuroscience and clinical research that will push the limits of our understanding of health and disease. |
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| AbstractList | Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes knowledge of neurodevelopment and brain maturation. However, much of human brain science is based on inferences from animal work and indirect neurochemical measures from body fluids. Neuroimaging can examine brain development directly in humans. The benefits can be enormous for learning how and when to intervene to prevent or treat a disorder. These unprecedented potential gains are countered by complex and difficult ethical issues. Technical advances can reduce ethical concerns by minimizing risks. They also promise to enhance the sensitivity and specificity of the measures (eg, by improving spatial and temporal resolution). Judiciously designed investigations will permit the testing of a priori hypotheses built on rational models of neuropathology. Finally, it is the integration of scientific knowledge across the various fields of neuroscience and clinical research that will push the limits of our understanding of health and disease. Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes knowledge of neurodevelopment and brain maturation. However, much of human brain science is based on inferences from animal work and indirect neurochemical measures from body fluids. Neuroimaging can examine brain development directly in humans. The benefits can be enormous for learning how and when to intervene to prevent or treat a disorder. These unprecedented potential gains are countered by complex and difficult ethical issues. Technical advances can reduce ethical concerns by minimizing risks. They also promise to enhance the sensitivity and specificity of the measures (eg, by improving spatial and temporal resolution). Judiciously designed investigations will permit the testing of a priori hypotheses built on rational models of neuropathology. Finally, it is the integration of scientific knowledge across the various fields of neuroscience and clinical research that will push the limits of our understanding of health and disease.Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes knowledge of neurodevelopment and brain maturation. However, much of human brain science is based on inferences from animal work and indirect neurochemical measures from body fluids. Neuroimaging can examine brain development directly in humans. The benefits can be enormous for learning how and when to intervene to prevent or treat a disorder. These unprecedented potential gains are countered by complex and difficult ethical issues. Technical advances can reduce ethical concerns by minimizing risks. They also promise to enhance the sensitivity and specificity of the measures (eg, by improving spatial and temporal resolution). Judiciously designed investigations will permit the testing of a priori hypotheses built on rational models of neuropathology. Finally, it is the integration of scientific knowledge across the various fields of neuroscience and clinical research that will push the limits of our understanding of health and disease. |
| Author | Ernst, Monique Rumsey, Judith M. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/11122944$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1002_1098_2779_2000_6_3_171__AID_MRDD4_3_0_CO_2_N crossref_primary_10_1148_radiology_216_3_r00au37672 crossref_primary_10_1016_S0278_2626_02_00521_3 crossref_primary_10_1016_j_jad_2004_05_014 crossref_primary_10_1111_j_1749_6632_2003_tb07095_x |
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| Snippet | Functional neuroimaging in child psychiatry presents unique scientific, ethical, and technical challenges. The study of childhood disorders presupposes... |
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| SubjectTerms | Adolescent Brain - anatomy & histology Brain - blood supply Cerebrovascular Circulation - physiology Child Child & adolescent psychiatry Child psychology Ethics Humans Magnetic Resonance Imaging Mental Disorders - diagnosis Neuroimaging Psychiatry Tomography, Emission-Computed Tomography, Emission-Computed, Single-Photon |
| Title | Functional neuroimaging in child psychiatry |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/11122944 https://www.proquest.com/docview/2406917749 https://www.proquest.com/docview/72529442 |
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