A CASE OF AN INVASIVE CRIBRIFORM BREAST CANCER-ITS SLOW-GROWTH AND DIFFICULTIES OF PRE -OPERATIVE DIAGNOSIS

An invasive cribriform breast cancer (ICC) that has a favorable prognosis was first described by Page et al. in 1983. We herein report a case of ICC, including the clinicopathological features. A 48-year-old Japanese woman visited our hospital, complaining of a lump after long-term observation. The...

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Published inNihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 67; no. 11; pp. 2554 - 2557
Main Authors URASHIMA, Tetsurou, MATSUI, Yoshifumi, OHTA, Takumi, TANIGUCHI, Tetsushi
Format Journal Article
LanguageEnglish
Published Japan Surgical Association 2006
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ISSN1345-2843
1882-5133
1882-5133
DOI10.3919/jjsa.67.2554

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Abstract An invasive cribriform breast cancer (ICC) that has a favorable prognosis was first described by Page et al. in 1983. We herein report a case of ICC, including the clinicopathological features. A 48-year-old Japanese woman visited our hospital, complaining of a lump after long-term observation. The tumor was located in the upper area of the right breast. It was 5cm in size, irregular shaped, elastically firm, accompanied by a dimple and fixation to the muscle was recognized. As its malignancy was suggested by ultrasound, computed tomography and magnetic resonance imaging, a core needle biopsy was performed twice. However, we could not reach the final pathological diagnosis. In 2003, radical mastectomy was performed and we finally obtained a pathological diagnosis of ICC (mixed type). The patient is now being followed up at an out-patient clinic without signs of recurrence. It was thought that ICC was slow-growing and ICC might have stratified to an entity that made pre-operative diagnosis by CNB not feasible.
AbstractList An invasive cribriform breast cancer (ICC) that has a favorable prognosis was first described by Page et al. in 1983. We herein report a case of ICC, including the clinicopathological features. A 48-year-old Japanese woman visited our hospital, complaining of a lump after long-term observation. The tumor was located in the upper area of the right breast. It was 5cm in size, irregular shaped, elastically firm, accompanied by a dimple and fixation to the muscle was recognized. As its malignancy was suggested by ultrasound, computed tomography and magnetic resonance imaging, a core needle biopsy was performed twice. However, we could not reach the final pathological diagnosis. In 2003, radical mastectomy was performed and we finally obtained a pathological diagnosis of ICC (mixed type). The patient is now being followed up at an out-patient clinic without signs of recurrence. It was thought that ICC was slow-growing and ICC might have stratified to an entity that made pre-operative diagnosis by CNB not feasible.
Author MATSUI, Yoshifumi
OHTA, Takumi
URASHIMA, Tetsurou
TANIGUCHI, Tetsushi
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References 8) Roses DF: Breast Cancer. Churchill Livingstone, Philadelphia, 2005, p112-113
5) Nishimura R, Ohsumi S, Teramoto N, et al: Invasive cribriform carcinoma with extensive microcarcification in the male breast. Breast Cancer 12: 145-148, 2005
3) 市原 周:乳腺病理学.名古屋大学出版,名古屋, 2000, p62-63
9) Rosen PP: Rosen's Breast Pathology. Lippincott Williams & Wilkins, Philadelphia, 2001, p551-553
4) 秋山 太,坂元吾偉,井内康輝他:「乳腺腫瘍の組織学的分類」の改正点について.第14回日乳癌会プログラム抄集: 146-147, 2006
2) Ellis IO, Cornelisse CJ, Schnitt SJ, et al: Tumors of the breast. In: Tavassoli FA, Devilee P eds. Pathology and genetics of tumours of the breast and female genital organs (World Health Organization Classification of Tumours) IARC Press, International Agency for Research on Cancer, Lyon, 2003, p9-112
6) 大石博晃,稲垣充也,植山 実他:乳腺Invasive cribriform carcinomaの2例.日臨細胞会誌 44: 115, 2005
7) Stuts JA, Evans AJ, Pinder S, et al: The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham breast team. Clin Radiol 49: 693-695, 1994
10) Marzullo F, Zito FA, Marzullo A, et al: Infiltrating cribriform carcinoma of the breast. A clinicopathologic and immunohistochemical study of 5 cases. Eur J Gynaecol oncol 17: 228-231, 1996
1) Page DL, Dixon JM, Anderson TJ, et al: Invasive cribriform carcinoma of the breast. Histopathology 7: 525-536, 1983
References_xml – reference: 5) Nishimura R, Ohsumi S, Teramoto N, et al: Invasive cribriform carcinoma with extensive microcarcification in the male breast. Breast Cancer 12: 145-148, 2005
– reference: 7) Stuts JA, Evans AJ, Pinder S, et al: The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham breast team. Clin Radiol 49: 693-695, 1994
– reference: 6) 大石博晃,稲垣充也,植山 実他:乳腺Invasive cribriform carcinomaの2例.日臨細胞会誌 44: 115, 2005
– reference: 10) Marzullo F, Zito FA, Marzullo A, et al: Infiltrating cribriform carcinoma of the breast. A clinicopathologic and immunohistochemical study of 5 cases. Eur J Gynaecol oncol 17: 228-231, 1996
– reference: 3) 市原 周:乳腺病理学.名古屋大学出版,名古屋, 2000, p62-63
– reference: 9) Rosen PP: Rosen's Breast Pathology. Lippincott Williams & Wilkins, Philadelphia, 2001, p551-553
– reference: 2) Ellis IO, Cornelisse CJ, Schnitt SJ, et al: Tumors of the breast. In: Tavassoli FA, Devilee P eds. Pathology and genetics of tumours of the breast and female genital organs (World Health Organization Classification of Tumours) IARC Press, International Agency for Research on Cancer, Lyon, 2003, p9-112
– reference: 4) 秋山 太,坂元吾偉,井内康輝他:「乳腺腫瘍の組織学的分類」の改正点について.第14回日乳癌会プログラム抄集: 146-147, 2006
– reference: 1) Page DL, Dixon JM, Anderson TJ, et al: Invasive cribriform carcinoma of the breast. Histopathology 7: 525-536, 1983
– reference: 8) Roses DF: Breast Cancer. Churchill Livingstone, Philadelphia, 2005, p112-113
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Title A CASE OF AN INVASIVE CRIBRIFORM BREAST CANCER-ITS SLOW-GROWTH AND DIFFICULTIES OF PRE -OPERATIVE DIAGNOSIS
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