ONTODerm - A domain ontology for dermatology

A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one su...

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Published inDermatology online journal Vol. 14; no. 6; p. 16
Main Author Eapen, Bell Raj
Format Journal Article
LanguageEnglish
Published United States University of California Digital Library - eScholarship 2008
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ISSN1087-2108
1087-2108
DOI10.5070/D379P7C1HC

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Abstract A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one such ontology called ONTODerm. ONTODerm is grounded on DOLCE Lite foundational ontology and its purpose is to address the unique needs of dermatology as a medical specialty. It is represented in Web Ontology Language (OWL) using the Protégé OWL Plugin. ONTODerm is available for download and collaborative development under GPL license.
AbstractList A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one such ontology called ONTODerm. ONTODerm is grounded on DOLCE Lite foundational ontology and its purpose is to address the unique needs of dermatology as a medical specialty. It is represented in Web Ontology Language (OWL) using the Protégé OWL Plugin. ONTODerm is available for download and collaborative development under GPL license.
ONTODerm - A domain ontology for dermatology.Bell Raj Eapen MSc MD DNBDermatology Online Journal 14 (6): 16Dip Derm (UK), Kaya Skin Clinic, Dubai, UAE. webmaster@gulfdoctor.net---A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one such ontology called ONTODerm. ONTODerm is grounded on DOLCE Lite foundational ontology and its purpose is to address the unique needs of dermatology as a medical specialty. It is represented in Web Ontology Language (OWL) using the Protégé OWL Plugin. ONTODerm is available for download and collaborative development under GPL license.---IntroductionOntology is an explicit formal specification of the terms in a particular domain and describes relations among them. Ontology defines the vocabulary and the interrelationships in a particular domain that can be shared. Many medical disciplines have developed general and specialty specific ontologies that domain experts can use to share and annotate information in their fields [1].Why develop ontology?Health practitioners are relying more and more on software systems for tasks ranging from electronic medical records maintenance to implementation of treatment guidelines. However, various legacy systems represent and manipulate data in several ways making data exchange, updating, and reuse in a different setting next to impossible [2, 3]. Investigators in the area of software engineering emphasize the importance of making ontologies explicit when building computer programs [4]. Ontology is neither a software program nor a module. It is a definition of the concepts in a domain and the relations among them that can be shared by several software agents so that they will all be based on the same semantics.It helps to keep the domain knowledge separate from the operational knowledge or the software system so that both can be altered without affecting the other. Any change made to the domain ontology can be easily propagated throughout the system components. It also helps in the reuse of the domain knowledge [1].The first step in developing an ontology includes defining classes and arranging them in a hierarchy. As a result, relations between these classes are described in an unambiguous way and the possible values are filled.Relevance of a specialty specific ontology for dermatologyDermatology is different in many ways from the other medical specialties and has semantics of its own. The terminologies often used by dermatologists to describe lesions are unique and not very familiar to other specialists [5]. Even the medications prescribed by dermatologists and the investigations they perform are different from other specialties. Hence having a specialty specific ontology is essential to integrate dermatology with other medical software systems.The Web Ontology LanguageThere are various ways of formally representing ontologies. As the World Wide Web is fast emerging as the popular data sharing platform, it is better to rely on a language that is optimized for the web for medical ontologies as well [6]. The Web Ontology Language is one such ontology language developed by the W3C Web Ontology Working Group [7]. The Web Ontology Language has more facilities for expressing meaning and semantics than other ontology languages like XML, RDF, and RDF-S. Thus, OWL goes beyond these languages in its ability to represent machine interpretable content, especially on the Web. The Web Ontology Language has 3 sublanguages: in order of decreasing expressiveness, they are OWL Full, OWL DL, and OWL Lite.OWL Basics [8]The basic components of OWL are classes, properties, individuals and the relationships between them. Classes are the basic building blocks of an OWL ontology arranged in a taxonomic hierarchy. For example Patients and Diseases are 2 good candidates for a top level class in a dermatology ontology. Properties can be categorized as object properties, which relate individuals to other individuals and datatype properties, which relate individuals to datatype values, such as integers, floats, and strings. A property can have a domain and range associated with it. There are various special types of properties such as functional, inverse functional, symmetric and transitive. A functional property can take only one value while two different individuals cannot have the same value in an inverse functional property. If a symmetric property links A to B, then one can infer that it links B to A. If a property links A to B and B to C, then if one can infer that it links A to C, that property is transitive. Individuals are instances of classes; properties can relate one individual to another. Various restrictions can be applied to classes and properties. Cardinality restrictions specify the number of relationships in which a class of individuals can participate. Existential restriction specifies the existence of at least one relationship along a given property to an individual that is a member of a specific class. To restrict the relationship for a given property to individuals that are members of a specific class, a universal restriction must be used. Detailed information about the OWL syntax is available from the W3C website [7].The Protégé Approach [9]Ontology development is a difficult task because it has to be represented in a restricted, formal language. Hence a visual development tool with a user friendly view is needed for creating ontology and for its maintenance. Protégé is one such generic and flexible, visual ontology development environment. In the Protégé approach the ontology is represented in a machine-readable format. This makes it possible for software systems to interact directly with the ontology. Protégé's powerful editing interface consists of several tabs that display different aspects of the ontology (Fig. 1). The details about a selected object are displayed by forms and widgets [10]. The functionalities of Protégé can be enhanced using plug-ins.The Protégé OWL Plugin [11]The OWL Plug-in is one such plug-in used to load and save ontology in OWL formats and to edit OWL ontologies using owl specific widgets. The Web Ontology Language plug-in provides the functionality to edit OWL classes, properties, forms, individuals, and ontology metadata within Protégé framework in place of the default frame model.Basics of ontology creation [12]Dermatology as a medical specialty is a very complex domain for modeling and representing intended meaning. Hence building domain ontology from scratch is a complicated task and it requires a general, foundational ontology to interoperate and support soft modularization. The foundational ontology implements the most appropriate set of principles and speed up the ontology building process as "reinventing the wheel" is avoided [13].During the specification stage of an ontology it is important to define the purpose of ontology. To make the ontology clear and unambiguous, knowledge units, not directly useful to the domain need to be avoided. It is also important to ensure that the ontology is coherent with consistent definitions, extensible with the addition of new concepts and has minimal encoding bias.The next step is to formalize the concept and to implement it using the appropriate tools. However, an ontology needs to be updated with new concepts and maintained. A good ontology will mature over time with the contribution from various domain experts.ONTODerm Methodologies and ProposalsONTODerm is grounded on the Dolce-Lite-Plus (DOLCE+), a foundation ontology that belongs to the "WonderWeb Foundational Ontology Library" [13]. It is expressed in the OWL DL language using the Protégé owl plug-in. As mentioned before, an ontology should represent only the intended models for its domain of interest for the tasks the ontology is meant to accomplish.ONTODerm is intended to serve as a specialty specific ontology that will complement the existing core Medical ontologies and the ones that will be developed in the future. Hence, ONTODerm concentrates on 6 important concepts for which dermatology has a unique view of the world different from the other medical specialties. They are:1. Description of lesions with terms like macule or papule2. Description of patients with terms like skin type or atopy3. Investigations (histopathological examination cytodiagnostic techniques, MED determination)4. Interventions (cosmetic procedures, various surgical treatments)5. Drugs in the form of lotions, creams or oral medications6. Grades or stages in the form of PASI, SLE DAI, and othersThese six concepts form the top level concepts for ONTODerm and are mapped to the DOLCE+ (Descriptive Ontology for Linguistic and Cognitive Engineering) foundation ontology as per Figure 2. This grounding of top level concepts is a difficult task because the foundation ontology has a broad philosophical view that applies to everything [13]. Moreover, the present grounding may not be the most appropriate one and it can evolve with the help of ontology experts.Only a few of the classes and properties are presently defined in ONTODerm. It is a project open to all domain and ontology experts licensed under GPL to contribute and enhance. The links to the project page [14] and ONTODerm wiki [15] are available from the project home page [16].Probable uses of ONTODermONTODerm is not a software system with a well defined set of uses. It is a system with which other software systems can interact. Hence, it is difficult to predict its possible uses. Potential uses include teaching, decision support for clinical practice, and semantic assistance for data processing tools. An example for the last mentioned use would be a context-sensitive search function for research articles even if they do not contain the correct keyword. Existing
A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one such ontology called ONTODerm. ONTODerm is grounded on DOLCE Lite foundational ontology and its purpose is to address the unique needs of dermatology as a medical specialty. It is represented in Web Ontology Language (OWL) using the Protégé OWL Plugin. ONTODerm is available for download and collaborative development under GPL license.A specialty specific ontology for dermatology can be a very useful tool for conveying an accurate meaning to collaborative guideline applications and software systems. This paper describes the basics of ontology and the need for ontology in dermatology. We also propose the basic structure for one such ontology called ONTODerm. ONTODerm is grounded on DOLCE Lite foundational ontology and its purpose is to address the unique needs of dermatology as a medical specialty. It is represented in Web Ontology Language (OWL) using the Protégé OWL Plugin. ONTODerm is available for download and collaborative development under GPL license.
Author Eapen, Bell Raj
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ONTODerm - A domain ontology for dermatology.Bell Raj Eapen MSc MD DNBDermatology Online Journal 14 (6): 16Dip Derm (UK), Kaya Skin Clinic, Dubai, UAE....
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SubjectTerms Bioinformatics
Clinical medicine
Collaboration
Computer Systems
Computers
Data exchange
Dermatology
Internet
Knowledge management
Language
Libraries
Ontology
Programming Languages
Semantics
Skin
Software engineering
Subject specialists
Systems Integration
Vocabulary, Controlled
Web Ontology Language-OWL
Title ONTODerm - A domain ontology for dermatology
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