Two Cases of Chondrosarcoma Treated by Local Resection

We experienced 2 cases of chondrosarcoma treated by wide local resection. Case 1, a 49 year-old woman, had a mass with a history of tumor formation for 5 or 6 years in the right 2nd and 3rd intermetacarpal region, which had been resected 20 years previously. This case was a very rare secondary chond...

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Published inOrthopedics & Traumatology Vol. 42; no. 1; pp. 383 - 386
Main Authors Takata, Naofumi, Yoshida, Haruhiko, Minamizaki, Takeshi, Kikkawa, Masamoto, Naniwa, Singo, Sumisaka, Osami, Yumoto, Tokichi, Furuse, Kiyoo, Nakamura, Yoshikazu
Format Journal Article
LanguageEnglish
Published West-Japanese Society of Orthopedics & Traumatology 1993
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ISSN0037-1033
1349-4333
1349-4333
DOI10.5035/nishiseisai.42.383

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Abstract We experienced 2 cases of chondrosarcoma treated by wide local resection. Case 1, a 49 year-old woman, had a mass with a history of tumor formation for 5 or 6 years in the right 2nd and 3rd intermetacarpal region, which had been resected 20 years previously. This case was a very rare secondary chondrosarcoma (Grade 1 in Evans' classification) originating from the 3rd metacarpal bone. She survives relapse-free without any limitation of ADL except for inability to use chopsticks at 30 months after wide local resection with a marginal margin. Case 2, a 46 year-old woman, had noticed tumor formation in her right thigh for 2 or 3 years. Roentgenographically the tumor was located from the femoral neck through to the mid-distal one third of the femoral shaft, and showed a ground glass appearance with a partial central radiolucent area and a thicker cortex. This case was diagnosed as pimary central chondrosarcoma (Grade 2 in Evans' classification). She has survived relapse-free, graded by Enneking's modified functional evaluation method as “Good” (25points) in the knee joint and “Fair” (20points) in hip joint 20months after wide local resection with a wide margin followed by total femoral replacement with a Kotz modular femur and tibia reconstruction system. Although she developed an allergic skin reaction to metal around the surgical scar at the knee joint 13 months after surgery, this completely disappeared with steroid ointment. No loosening has been seen.
AbstractList We experienced 2 cases of chondrosarcoma treated by wide local resection. Case 1, a 49 year-old woman, had a mass with a history of tumor formation for 5 or 6 years in the right 2nd and 3rd intermetacarpal region, which had been resected 20 years previously. This case was a very rare secondary chondrosarcoma (Grade 1 in Evans' classification) originating from the 3rd metacarpal bone. She survives relapse-free without any limitation of ADL except for inability to use chopsticks at 30 months after wide local resection with a marginal margin. Case 2, a 46 year-old woman, had noticed tumor formation in her right thigh for 2 or 3 years. Roentgenographically the tumor was located from the femoral neck through to the mid-distal one third of the femoral shaft, and showed a ground glass appearance with a partial central radiolucent area and a thicker cortex. This case was diagnosed as pimary central chondrosarcoma (Grade 2 in Evans' classification). She has survived relapse-free, graded by Enneking's modified functional evaluation method as “Good” (25points) in the knee joint and “Fair” (20points) in hip joint 20months after wide local resection with a wide margin followed by total femoral replacement with a Kotz modular femur and tibia reconstruction system. Although she developed an allergic skin reaction to metal around the surgical scar at the knee joint 13 months after surgery, this completely disappeared with steroid ointment. No loosening has been seen.
Author Takata, Naofumi
Furuse, Kiyoo
Sumisaka, Osami
Nakamura, Yoshikazu
Naniwa, Singo
Minamizaki, Takeshi
Yoshida, Haruhiko
Kikkawa, Masamoto
Yumoto, Tokichi
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References 8) 望月恵子, 本田まり子, 新村眞人, 他: 骨接合用金属による接触皮膚炎. 皮膚病診療 8: 751-754, 1986.
10) Webley, M., Kates, A. and Snaith, M.: Metal sensitivity in patients with a hinge arthroplasty of the knee. Ann Rheum Dis 37: 373-375,1978.
9) 須田暁, 伊藤忠厚, 白井康正, 他: 当科における手の腫瘍症例について. 整形外科 33: 1697-1699, 1982.
1) Enneking, W. F.: Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. Limb Salvage in Musculoskeletal Oncology, ed. by Enneking, W. F., Churchill Livingstone, New York, 1987, pp. 626-639.
2) Evans, E. M., Freeman, M. A. R., Miller, A. J., et al: Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement. J. Bone Joint Surg. 56B: 626-642, 1974.
5) 国立ガンセンター: 全国骨腫瘍患者登録一覧表 (昭和62年). 三田村村印刷, 東京, 1989, pp. 130-131.
6) 姜武, 中嶋洋, 河井秀夫, 他: 手の骨腫瘍の治療成績. 整形外科 33: 1703-1705, 1982.
7) Mirra, J. M.: Bone Tumors Vol 1 and 2. Lea and Febiger, Philadelphia London, 1989, pp. 510-514, pp. 520-532 and pp. 1660-1673.
3) Evans, H. L., Ayala, A. G. and Romsdahl, M. M.: Prognostic factors in chondrosarcoma of bone. Cancer 40: 818-831, 1977.
4) 稲田治, 三木純, 森尾泰夫, 他; 手の骨・軟部腫瘍の治療経験. 整形外科 32: 1695-1697, 1981.
References_xml – reference: 1) Enneking, W. F.: Modification of the system for functional evaluation of surgical management of musculoskeletal tumors. Limb Salvage in Musculoskeletal Oncology, ed. by Enneking, W. F., Churchill Livingstone, New York, 1987, pp. 626-639.
– reference: 10) Webley, M., Kates, A. and Snaith, M.: Metal sensitivity in patients with a hinge arthroplasty of the knee. Ann Rheum Dis 37: 373-375,1978.
– reference: 6) 姜武, 中嶋洋, 河井秀夫, 他: 手の骨腫瘍の治療成績. 整形外科 33: 1703-1705, 1982.
– reference: 5) 国立ガンセンター: 全国骨腫瘍患者登録一覧表 (昭和62年). 三田村村印刷, 東京, 1989, pp. 130-131.
– reference: 4) 稲田治, 三木純, 森尾泰夫, 他; 手の骨・軟部腫瘍の治療経験. 整形外科 32: 1695-1697, 1981.
– reference: 8) 望月恵子, 本田まり子, 新村眞人, 他: 骨接合用金属による接触皮膚炎. 皮膚病診療 8: 751-754, 1986.
– reference: 7) Mirra, J. M.: Bone Tumors Vol 1 and 2. Lea and Febiger, Philadelphia London, 1989, pp. 510-514, pp. 520-532 and pp. 1660-1673.
– reference: 3) Evans, H. L., Ayala, A. G. and Romsdahl, M. M.: Prognostic factors in chondrosarcoma of bone. Cancer 40: 818-831, 1977.
– reference: 9) 須田暁, 伊藤忠厚, 白井康正, 他: 当科における手の腫瘍症例について. 整形外科 33: 1697-1699, 1982.
– reference: 2) Evans, E. M., Freeman, M. A. R., Miller, A. J., et al: Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement. J. Bone Joint Surg. 56B: 626-642, 1974.
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