Effectiveness of health guidance on the outcomes of specific health checkup in National Health Insurance subscribers

Objective: We aimed to evaluate the effectiveness of specific health guidance on the outcomes of health checkup in a three-year continuing screening program for a large population.Methods: Among the 422,389 examinees of the specific health checkup system, individuals undergoing a three-year continui...

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Published inJapanese Journal of Health and Human Ecology Vol. 85; no. 6; pp. 216 - 230
Main Authors KINOSHITA, Setsuko, KAYABA, Kazunori, NOBUHARA, Hiroaki
Format Journal Article
LanguageJapanese
Published Tokyo The Japanese Society of Health and Human Ecology 30.11.2019
Japan Science and Technology Agency
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ISSN2432-6712
2432-6720
DOI10.3861/kenko.85.6_216

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Abstract Objective: We aimed to evaluate the effectiveness of specific health guidance on the outcomes of health checkup in a three-year continuing screening program for a large population.Methods: Among the 422,389 examinees of the specific health checkup system, individuals undergoing a three-year continuing screening from 2008 to 2010 were divided into nine groups according to the existence or non-existence of health guidance practices. We compared the outcomes of the health checkups conducted in 2008 and those conducted in 2010 for 84,831 men and 132,449 women. More specifically, we analyzed the annual changes in the clinical measurements using the generalized linear model with the ages recorded in 2008 as covariates. Further, the annual changes in the prevalence of metabolic syndrome, obesity, dyslipidemia, hypertension, impaired glucose tolerance, and smoking were examined using the McNemar test.Results: The participants who received health guidance in 2008 and did not need guidance in 2009 revealed the greatest change rate in mean body mass index reduction, mean waist circumference re duction, mean triglyceride levels, and mean high-density lipoprotein levels compared with those who needed health guidance in 2008. The participants who received health guidance in both 2008 and 2009 revealed the greatest reduction in the prevalence of obesity for men and women [men, −12.1 percent points (pp), p<0.001; women, −14.9 pp, p<0.001].Discussion: Although the unrandomized controlled study, the statistical phenomenon of regression to the mean, and selection bias could be limitations, a positive effect of health guidance was observed on the outcomes of the health checkups for a large population.
AbstractList Objective: We aimed to evaluate the effectiveness of specific health guidance on the outcomes of health checkup in a three-year continuing screening program for a large population. Methods: Among the 422,389 examinees of the specific health checkup system, individuals undergoing a three-year continuing screening from 2008 to 2010 were divided into nine groups according to the existence or non-existence of health guidance practices. We compared the outcomes of the health checkups conducted in 2008 and those conducted in 2010 for 84,831 men and 132,449 women. More specifically, we analyzed the annual changes in the clinical measurements using the generalized linear model with the ages recorded in 2008 as covariates. Further, the annual changes in the prevalence of metabolic syndrome, obesity, dyslipidemia, hypertension, impaired glucose tolerance, and smoking were examined using the McNemar test. Results: The participants who received health guidance in 2008 and did not need guidance in 2009 revealed the greatest change rate in mean body mass index reduction, mean waist circumference re duction, mean triglyceride levels, and mean high-density lipoprotein levels compared with those who needed health guidance in 2008. The participants who received health guidance in both 2008 and 2009 revealed the greatest reduction in the prevalence of obesity for men and women [men, −12.1 percent points (pp), p<0.001; women, −14.9 pp, p<0.001]. Discussion: Although the unrandomized controlled study, the statistical phenomenon of regression to the mean, and selection bias could be limitations, a positive effect of health guidance was observed on the outcomes of the health checkups for a large population.
Author KINOSHITA, Setsuko
NOBUHARA, Hiroaki
KAYABA, Kazunori
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References 38) 標準的な健診・保健指導プログラム【改訂版】.厚生労働省.http://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/kenkou/seikatsu/index.html(2014年7月9日)
2) Watanabe M, Yamaoka K, Yokotsuka M, et al. Randomized controlled trial of a new dietary education program to prevent type 2 diabetes in a high-risk group of Japanese male workers. Diabetes Care, 2003; 26: 3209-3214.
26) Greenlee H, Strizich G, Lovasi GS, et al. Concordance With Prevention Guidelines and Subsequent Cancer, Cardiovascular Disease, and Mortality: A Longitudinal Study of Older Adults. Am J Epidemiol, 2017; 186: 1168-1179.
30) Jankovic N, Geelen A, Streppel MT, et al. Adherence to a healthy diet according to the World Health Organization guidelines and all-cause mortality in elderly adults from Europe and the United States. Am J Epidemiol, 2014; 180: 978-988.
25) Dunkley AJ, Bodicoat DH, Greaves CJ, et al. Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations. Diabetes Care, 2014; 37: 922-933.
33) Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med, 2001; 344: 1343-1350.
11) 林 芙美,武見ゆかり,奥山 恵,他.特定保健指導の積極的支援における支援者用ツール「脱メタボリックシンドローム用食・生活支援ガイド」の導入とその評価.日健教誌,2015;23:87-98
23) Becker MH, Janz NK. Behavioral science perspectives on health hazard/health risk appraisal. Health Serv Res, 1987; 22: 537-551.
19) van Dam RM, Li T, Spiegelman D, et al. Combined impact of lifestyle factors on mortality: prospective cohort study in US women. BMJ, 2008; 337: a1440.
34) Aguiar EJ, Morgan PJ, Collins CE, et al. Efficacy of the Type 2 Diabetes Prevention Using LifeStyle Education Program RCT. Am J Prev Med, 2016; 50: 353-364.
5) 村本あき子,加藤綾子,津下一代.市町村国保におけるメタボリックシンドローム対策のための積極的支援型保健指導プログラムの一年後の効果評価.日健教誌,2010;18:175-185
28) Lelong H, Blacher J, Baudry J, et al. Individual and Combined Effects of Dietary Factors on Risk of Incident Hypertension: Prospective Analysis From the NutriNet-Santé Cohort. Hypertension, 2017; 70: 712-720.
36) Jackson SL, Long Q, Rhee M, et al. Weight Loss and Diabetes Incidence with the VA Lifestyle Change Program. Lancet Diabetes Endocrinol, 2015; 3: 173-180.
41) Selvin E, Steffes MW, Zhu H, et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med, 2010; 362: 800-811.
9) 吉川彰一,小川俊夫,馬場武彦,他.特定健康診査・特定保健指導の効果分析.厚生の指標,2014;61:33-40
18) Chiuve SE, Fung TT, Rexrode KM, et al. Adherence to a low-risk, healthy lifestyle and risk of sudden cardiac death among women. JAMA, 2011; 306: 62-69.
12) 辻 久子,塩島一朗.特定保健指導の効果メタボリック・シンドローム指標の4年間の評価.日本公衛誌,2015;62:402-411
27) Lv J, Yu C, Guo Y, et al. Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults. Int J Epidemiol, 2017; 46: 1410-1420.
35) Tsushita K, S Hosler A, Miura K, et al. Rationale and Descriptive Analysis of Specific Health Guidance: the Nationwide Lifestyle Intervention Program Targeting Metabolic Syndrome in Japan. J Atheroscler Thromb, 2017; Dec.12: [Epub ahead of print](2018年1月27日).
4) 森口次郎,松尾福子,江島桐子,他.特定保健指導プログラムのメタボリックシンドローム予防における効果の検討.人間ドック,2011;26:75-79
13) 豊田将之,村本あき子,津下一代.多量飲酒者に対する通常の特定保健指導の効果-非飲酒者,少量飲酒者との比較-.人間ドック,2016;31:39-47
24) Williamson DA, Rejeski J, Lang W, et al. Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med, 2009; 169: 163-171.
29) Khera AV, Emdin CA, Drake I, et al. Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med, 2016; 375: 2349-2358.
8) 春山康夫,武藤孝司,中出麻紀子,他.市町村国民健康保険加入者における特定保健指導後のメタボリックシンドローム改善効果.日本公衛誌,2012;10:731-742
16) Chao J, Wang Y, Xu H, et al. The effect of community-based health management on the health of the elderly: a randomized controlled trial from China. BMC Health Services Research, 2012; 12: 449.
3) Watanabe M, Okayama A, Shimamoto K, et al. Short-term effectiveness of an individual counseling program for impaired fasting glucose and mild type 2 diabetes in Japan: a multi-center randomized control trial. Asia Pac J Clin Nutr, 2007; 16: 489-497.
20) Knoops KT, de Groot LC, Kromhout D, et al. Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA, 2004; 292: 1433-1439.
1) 標準的な健診・保健指導プログラム(確定版).厚生労働省.http://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/kenkou/seikatsu/link-list.html (2014年7月9日)
7) 特定健診・保健指導の医療費適正化効果等の検証のためのワーキンググループ中間取りまとめ.平成26年4月.厚生労働省.http://www.mhlw.go.jp/stf/shingi/0000044342.html(2017年10月30日)
42) Heianza Y, Arase Y, Fujihara K, et al. Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes: the Toranomon Hospital Health Management Center Study 7 (TOPICS 7). Diabetes Care, 2012; 35: 1050-1052.
14) 真殿亜季,由田克士,栗林 徹,他.特定保健指導における1年後・2年後の減量達成に関連する生活習慣.人間ドック,2017;32:456-462
17) Stampfer MJ, Hu FB, Manson JE, et al. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med, 2000; 343: 16-22.
32) Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med, 2002; 346: 393-403.
10) Muramoto A, Matsushita M, Kato A, et al. Three percent weight reduction is the minimum requirement to improve healthhazards in obese and overweight people in Japan. Obes Res Clin Pract, 2014; 8: e466-475.
40) Kayaba K, Nago N, Miyamoto T, et al. Glycated hemoglobin levels and their correlation with atherosclerotic risk factors in a Japanese population--the Jichi Medical School Cohort Study 1993-1995. Jpn Circ J, 1998; 62: 261-266.
22) 宗像恒治.保健行動の実行を支える諸条件.看護技術,1983;29:1866-1874
21) Ford ES, Bergmann MM, Boeing H, et al. Healthy lifestyle behaviors and all-cause mortality among adults in the United States. Prev Med, 2012; 55: 23-27.
15) Gamble T, Haley D, Buck R, et al. Designing randomized controlled trials (RCTs). In: Guest G, Namey E, editors. Public health research methods. Los Angeles: SAGE, 2014: 223-250.
39) Selvin E, Crainiceanu CM, Brancati FL, et al. Short-term variability in measures of glycemia and implications for the classification of diabetes. Arch Intern Med, 2007; 167: 1545-1551.
31) Blackford K, Jancey J, Lee AH, et al. Home-based lifestyle intervention for rural adults improves metabolic syndrome parameters and cardiovascular risk factors: A randomized controlled trial. Prev Med, 2016; 89: 15-22.
37) Sakane N, Sato J, Tsushita K, et al. Prevention of type 2 diabetes in a primary healthcare setting: three-year results of lifestyle intervention in Japanese subjects with impaired glucose tolerance. BMC Public Health, 2011; 11: 40.
6) 笠松亜希,奥山 恵,小山由香里,他.特定保健指導実施後の体重と腹囲の減少による検査データの変化.人間ドック,2010;25:77-83
References_xml – reference: 18) Chiuve SE, Fung TT, Rexrode KM, et al. Adherence to a low-risk, healthy lifestyle and risk of sudden cardiac death among women. JAMA, 2011; 306: 62-69.
– reference: 15) Gamble T, Haley D, Buck R, et al. Designing randomized controlled trials (RCTs). In: Guest G, Namey E, editors. Public health research methods. Los Angeles: SAGE, 2014: 223-250.
– reference: 21) Ford ES, Bergmann MM, Boeing H, et al. Healthy lifestyle behaviors and all-cause mortality among adults in the United States. Prev Med, 2012; 55: 23-27.
– reference: 1) 標準的な健診・保健指導プログラム(確定版).厚生労働省.http://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/kenkou/seikatsu/link-list.html (2014年7月9日).
– reference: 24) Williamson DA, Rejeski J, Lang W, et al. Impact of a weight management program on health-related quality of life in overweight adults with type 2 diabetes. Arch Intern Med, 2009; 169: 163-171.
– reference: 34) Aguiar EJ, Morgan PJ, Collins CE, et al. Efficacy of the Type 2 Diabetes Prevention Using LifeStyle Education Program RCT. Am J Prev Med, 2016; 50: 353-364.
– reference: 41) Selvin E, Steffes MW, Zhu H, et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med, 2010; 362: 800-811.
– reference: 27) Lv J, Yu C, Guo Y, et al. Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults. Int J Epidemiol, 2017; 46: 1410-1420.
– reference: 3) Watanabe M, Okayama A, Shimamoto K, et al. Short-term effectiveness of an individual counseling program for impaired fasting glucose and mild type 2 diabetes in Japan: a multi-center randomized control trial. Asia Pac J Clin Nutr, 2007; 16: 489-497.
– reference: 39) Selvin E, Crainiceanu CM, Brancati FL, et al. Short-term variability in measures of glycemia and implications for the classification of diabetes. Arch Intern Med, 2007; 167: 1545-1551.
– reference: 17) Stampfer MJ, Hu FB, Manson JE, et al. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med, 2000; 343: 16-22.
– reference: 9) 吉川彰一,小川俊夫,馬場武彦,他.特定健康診査・特定保健指導の効果分析.厚生の指標,2014;61:33-40.
– reference: 13) 豊田将之,村本あき子,津下一代.多量飲酒者に対する通常の特定保健指導の効果-非飲酒者,少量飲酒者との比較-.人間ドック,2016;31:39-47.
– reference: 29) Khera AV, Emdin CA, Drake I, et al. Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med, 2016; 375: 2349-2358.
– reference: 2) Watanabe M, Yamaoka K, Yokotsuka M, et al. Randomized controlled trial of a new dietary education program to prevent type 2 diabetes in a high-risk group of Japanese male workers. Diabetes Care, 2003; 26: 3209-3214.
– reference: 40) Kayaba K, Nago N, Miyamoto T, et al. Glycated hemoglobin levels and their correlation with atherosclerotic risk factors in a Japanese population--the Jichi Medical School Cohort Study 1993-1995. Jpn Circ J, 1998; 62: 261-266.
– reference: 5) 村本あき子,加藤綾子,津下一代.市町村国保におけるメタボリックシンドローム対策のための積極的支援型保健指導プログラムの一年後の効果評価.日健教誌,2010;18:175-185.
– reference: 8) 春山康夫,武藤孝司,中出麻紀子,他.市町村国民健康保険加入者における特定保健指導後のメタボリックシンドローム改善効果.日本公衛誌,2012;10:731-742.
– reference: 14) 真殿亜季,由田克士,栗林 徹,他.特定保健指導における1年後・2年後の減量達成に関連する生活習慣.人間ドック,2017;32:456-462.
– reference: 22) 宗像恒治.保健行動の実行を支える諸条件.看護技術,1983;29:1866-1874.
– reference: 11) 林 芙美,武見ゆかり,奥山 恵,他.特定保健指導の積極的支援における支援者用ツール「脱メタボリックシンドローム用食・生活支援ガイド」の導入とその評価.日健教誌,2015;23:87-98.
– reference: 32) Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med, 2002; 346: 393-403.
– reference: 16) Chao J, Wang Y, Xu H, et al. The effect of community-based health management on the health of the elderly: a randomized controlled trial from China. BMC Health Services Research, 2012; 12: 449.
– reference: 28) Lelong H, Blacher J, Baudry J, et al. Individual and Combined Effects of Dietary Factors on Risk of Incident Hypertension: Prospective Analysis From the NutriNet-Santé Cohort. Hypertension, 2017; 70: 712-720.
– reference: 35) Tsushita K, S Hosler A, Miura K, et al. Rationale and Descriptive Analysis of Specific Health Guidance: the Nationwide Lifestyle Intervention Program Targeting Metabolic Syndrome in Japan. J Atheroscler Thromb, 2017; Dec.12: [Epub ahead of print](2018年1月27日).
– reference: 42) Heianza Y, Arase Y, Fujihara K, et al. Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes: the Toranomon Hospital Health Management Center Study 7 (TOPICS 7). Diabetes Care, 2012; 35: 1050-1052.
– reference: 19) van Dam RM, Li T, Spiegelman D, et al. Combined impact of lifestyle factors on mortality: prospective cohort study in US women. BMJ, 2008; 337: a1440.
– reference: 12) 辻 久子,塩島一朗.特定保健指導の効果メタボリック・シンドローム指標の4年間の評価.日本公衛誌,2015;62:402-411.
– reference: 26) Greenlee H, Strizich G, Lovasi GS, et al. Concordance With Prevention Guidelines and Subsequent Cancer, Cardiovascular Disease, and Mortality: A Longitudinal Study of Older Adults. Am J Epidemiol, 2017; 186: 1168-1179.
– reference: 37) Sakane N, Sato J, Tsushita K, et al. Prevention of type 2 diabetes in a primary healthcare setting: three-year results of lifestyle intervention in Japanese subjects with impaired glucose tolerance. BMC Public Health, 2011; 11: 40.
– reference: 7) 特定健診・保健指導の医療費適正化効果等の検証のためのワーキンググループ中間取りまとめ.平成26年4月.厚生労働省.http://www.mhlw.go.jp/stf/shingi/0000044342.html(2017年10月30日).
– reference: 23) Becker MH, Janz NK. Behavioral science perspectives on health hazard/health risk appraisal. Health Serv Res, 1987; 22: 537-551.
– reference: 4) 森口次郎,松尾福子,江島桐子,他.特定保健指導プログラムのメタボリックシンドローム予防における効果の検討.人間ドック,2011;26:75-79.
– reference: 6) 笠松亜希,奥山 恵,小山由香里,他.特定保健指導実施後の体重と腹囲の減少による検査データの変化.人間ドック,2010;25:77-83.
– reference: 36) Jackson SL, Long Q, Rhee M, et al. Weight Loss and Diabetes Incidence with the VA Lifestyle Change Program. Lancet Diabetes Endocrinol, 2015; 3: 173-180.
– reference: 33) Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med, 2001; 344: 1343-1350.
– reference: 10) Muramoto A, Matsushita M, Kato A, et al. Three percent weight reduction is the minimum requirement to improve healthhazards in obese and overweight people in Japan. Obes Res Clin Pract, 2014; 8: e466-475.
– reference: 30) Jankovic N, Geelen A, Streppel MT, et al. Adherence to a healthy diet according to the World Health Organization guidelines and all-cause mortality in elderly adults from Europe and the United States. Am J Epidemiol, 2014; 180: 978-988.
– reference: 38) 標準的な健診・保健指導プログラム【改訂版】.厚生労働省.http://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/kenkou/seikatsu/index.html(2014年7月9日).
– reference: 20) Knoops KT, de Groot LC, Kromhout D, et al. Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA, 2004; 292: 1433-1439.
– reference: 25) Dunkley AJ, Bodicoat DH, Greaves CJ, et al. Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations. Diabetes Care, 2014; 37: 922-933.
– reference: 31) Blackford K, Jancey J, Lee AH, et al. Home-based lifestyle intervention for rural adults improves metabolic syndrome parameters and cardiovascular risk factors: A randomized controlled trial. Prev Med, 2016; 89: 15-22.
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Snippet Objective: We aimed to evaluate the effectiveness of specific health guidance on the outcomes of health checkup in a three-year continuing screening program...
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SubjectTerms Body mass index
Body size
Dyslipidemia
Generalized linear models
Glucose tolerance
Health
Health guidance
Hypertension
Large population
Metabolic disorders
Metabolic syndrome
National health insurance
Obesity
Reduction
Regression analysis
Screening
Specific health checkup
Statistical analysis
Statistical models
Triglycerides
Women
Title Effectiveness of health guidance on the outcomes of specific health checkup in National Health Insurance subscribers
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