Imaging of the cervical carotid artery
Multiple modalities for imaging of the cervical carotid artery (CA) are reviewed, and their indications for obstructive carotid diseases are discussed. Ultrasonography is a completely non-invasive modality. It is not only a primary tool for screening of the carotid artery but is capable of minute ti...
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| Published in | Japanese Journal of Stroke Vol. 25; no. 4; pp. 382 - 385 |
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| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
The Japan Stroke Society
2003
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0912-0726 1883-1923 1883-1923 |
| DOI | 10.3995/jstroke.25.382 |
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| Abstract | Multiple modalities for imaging of the cervical carotid artery (CA) are reviewed, and their indications for obstructive carotid diseases are discussed. Ultrasonography is a completely non-invasive modality. It is not only a primary tool for screening of the carotid artery but is capable of minute tissue characterization and flow velocity measurements, which will be discussed in detail somewhere else in this symposium. The standard method for MR angiography (MRA) for the cervical CA is contrast-enhanced MRA (CE-MRA), which employs T1shortening by intravenous gadolinium chelate injection. With use of dedicated neurovascular coil, MRA of the major cervical arteries from the aortic arch up to the skull base is obtained in 15 seconds. Although the spatial resolution is limited and there is possible signal loss from phase dispersion caused by non-laminar flow, it is a minimally invasive method for screening of the cervical arteries. Recent introduction of parallel imaging technology has added multi-phase capability to CE-MRA. CT angiography is another standard modality for carotid imaging. With advent of multi-detector CT (MDCT) scanner, it is possible to acquire isotropic three-dimensional data set of the whole range of cervical vessels in a few seconds, minimizing motion artifact from pulsation and respiration. With its capability of high spatial resolusion imaging, it will replace conventional angiography in most of the clinical settings. Plaque imaging by MRI is a novel method to evaluate carotid plaque using special high-resolution imaging technique such as black blood sequence. Its clinical goal is to identify vulnerable plaque by characterization with multi-sequence imaging. A few of the imaging features indicative of vulnerable plaque include contrast enhancement on post contrast T1-weighted images and disruption of fibrous cap on T2 * -weighted images. |
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| AbstractList | Multiple modalities for imaging of the cervical carotid artery (CA) are reviewed, and their indications for obstructive carotid diseases are discussed. Ultrasonography is a completely non-invasive modality. It is not only a primary tool for screening of the carotid artery but is capable of minute tissue characterization and flow velocity measurements, which will be discussed in detail somewhere else in this symposium. The standard method for MR angiography (MRA) for the cervical CA is contrast-enhanced MRA (CE-MRA), which employs T1shortening by intravenous gadolinium chelate injection. With use of dedicated neurovascular coil, MRA of the major cervical arteries from the aortic arch up to the skull base is obtained in 15 seconds. Although the spatial resolution is limited and there is possible signal loss from phase dispersion caused by non-laminar flow, it is a minimally invasive method for screening of the cervical arteries. Recent introduction of parallel imaging technology has added multi-phase capability to CE-MRA. CT angiography is another standard modality for carotid imaging. With advent of multi-detector CT (MDCT) scanner, it is possible to acquire isotropic three-dimensional data set of the whole range of cervical vessels in a few seconds, minimizing motion artifact from pulsation and respiration. With its capability of high spatial resolusion imaging, it will replace conventional angiography in most of the clinical settings. Plaque imaging by MRI is a novel method to evaluate carotid plaque using special high-resolution imaging technique such as black blood sequence. Its clinical goal is to identify vulnerable plaque by characterization with multi-sequence imaging. A few of the imaging features indicative of vulnerable plaque include contrast enhancement on post contrast T1-weighted images and disruption of fibrous cap on T2 * -weighted images. |
| Author | Momoshima, Suketaka |
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| Copyright | The Japan Stroke Society |
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| References | 2) Okumura A, Araki Y, Nishimura Y, et al : The clinical utility of contrast-enhanced 3D MR angiography for cerebrovascular disease. Neurol Res 23: 767-71.2001 3) Phillips CD. Bubash LA : CT angiography and MR angiography in the evaluation of extracranial carotid vascular disease. Radiol Clin North Am. 40: 783-98.2002 7) Fayad ZA, Fuster V : Clinical imaging of the highrisk or vulnerable atherosclerotic plaque. Circ Res 89: 305-16.2001 8) Yuan C, Kerwin WS, Ferguson MS, et al : Contrast-enhanced high resolution MRI for atherosclerotic carotid artery tissue characterization. J Magn Reson Imaging. 15: 62-7, 2002 6) Walker LJ, Ismail A, McMeekin W, et al : Computed tomography angiography for the evaluation of carotid atherosclerotic plaque : correlation with histopathology of endarterectomy specimens. Stroke 33: 977-81, 2002 9) Yuan C, Zhang SX, Polissar NL, et al : Identification of fibrous cap rupture with magnetic resonance imaging is highly associated with recent transient ischemic attack or stroke. Circulation 15 ; 105: 181-5, 2002 5) Moll R, Dinkel HP: Value of the CT angiography in the diagnosis of common carotid artery bifurcation disease : CT angiography versus digital subtraction angiography and color flow Doppler. Eur J Radiol 39: 155-62, 2001 1) Golay X. Brown SJ, Itoh R, et al : Time-resolved contrast-enhanced carotid MR angiography using sensitivity encoding (SENSE). Am J Neuroradiol 22: 1615-9.2001 4) Berg MH, Manninen HI, Rasanen HT, et al : CT angiography in the assessment of carotid artery atherosclerosis. Acta Radiol 43: 116-24. 2002 |
| References_xml | – reference: 5) Moll R, Dinkel HP: Value of the CT angiography in the diagnosis of common carotid artery bifurcation disease : CT angiography versus digital subtraction angiography and color flow Doppler. Eur J Radiol 39: 155-62, 2001 – reference: 2) Okumura A, Araki Y, Nishimura Y, et al : The clinical utility of contrast-enhanced 3D MR angiography for cerebrovascular disease. Neurol Res 23: 767-71.2001 – reference: 9) Yuan C, Zhang SX, Polissar NL, et al : Identification of fibrous cap rupture with magnetic resonance imaging is highly associated with recent transient ischemic attack or stroke. Circulation 15 ; 105: 181-5, 2002 – reference: 8) Yuan C, Kerwin WS, Ferguson MS, et al : Contrast-enhanced high resolution MRI for atherosclerotic carotid artery tissue characterization. J Magn Reson Imaging. 15: 62-7, 2002 – reference: 1) Golay X. Brown SJ, Itoh R, et al : Time-resolved contrast-enhanced carotid MR angiography using sensitivity encoding (SENSE). Am J Neuroradiol 22: 1615-9.2001 – reference: 7) Fayad ZA, Fuster V : Clinical imaging of the highrisk or vulnerable atherosclerotic plaque. Circ Res 89: 305-16.2001 – reference: 6) Walker LJ, Ismail A, McMeekin W, et al : Computed tomography angiography for the evaluation of carotid atherosclerotic plaque : correlation with histopathology of endarterectomy specimens. Stroke 33: 977-81, 2002 – reference: 3) Phillips CD. Bubash LA : CT angiography and MR angiography in the evaluation of extracranial carotid vascular disease. Radiol Clin North Am. 40: 783-98.2002 – reference: 4) Berg MH, Manninen HI, Rasanen HT, et al : CT angiography in the assessment of carotid artery atherosclerosis. Acta Radiol 43: 116-24. 2002 |
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| Title | Imaging of the cervical carotid artery |
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