LEUKOCYTE REDUCTION FILTERS AND INFUSION DEVICE FOR RED BLOOD CELL TRANSFUSION
we studied the influence on blood cells when red blood cells were filtered with leukocyte reduction filters under the midpress-type infusion pump. At regular (5ml/min) and high (20ml/min) flow rates of infusion, red blood cells were filtered with a small delay. Filtered blood cells showed less damag...
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| Published in | Journal of the Japan Society of Blood Transfusion Vol. 49; no. 3; pp. 449 - 454 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
The Japan Society of Transfusion Medicine and Cell Therapy
2003
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0546-1448 1883-8383 |
| DOI | 10.3925/jjtc1958.49.449 |
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| Abstract | we studied the influence on blood cells when red blood cells were filtered with leukocyte reduction filters under the midpress-type infusion pump. At regular (5ml/min) and high (20ml/min) flow rates of infusion, red blood cells were filtered with a small delay. Filtered blood cells showed less damaged with regard to red cell morphology. A negligible increase in supernatant hemoglobin concentration was detected in filtered blood products, but no significant increase in supernatant potassium concentration was observed. The number of residual white blood cells after filtration was significantly reduced even at the forced high flow rate of infusion. Our results show that leukocyte reduction filters (Purecell RC and Imugard III-RC) are safely applicable to the midpress-type infusion pump for red blood cell transfusion. |
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| AbstractList | we studied the influence on blood cells when red blood cells were filtered with leukocyte reduction filters under the midpress-type infusion pump. At regular (5ml/min) and high (20ml/min) flow rates of infusion, red blood cells were filtered with a small delay. Filtered blood cells showed less damaged with regard to red cell morphology. A negligible increase in supernatant hemoglobin concentration was detected in filtered blood products, but no significant increase in supernatant potassium concentration was observed. The number of residual white blood cells after filtration was significantly reduced even at the forced high flow rate of infusion. Our results show that leukocyte reduction filters (Purecell RC and Imugard III-RC) are safely applicable to the midpress-type infusion pump for red blood cell transfusion. |
| Author | Morino, Sakiko Fujino, Shinji Henmi, Junko Buseki, Yuuji Takagi, Shojiro |
| Author_xml | – sequence: 1 fullname: Morino, Sakiko organization: Department of Blood Transfusion, Omiya Medical Center, Jichi Medical School – sequence: 1 fullname: Takagi, Shojiro organization: Department of Blood Transfusion, Omiya Medical Center, Jichi Medical School – sequence: 1 fullname: Buseki, Yuuji organization: Department of Blood Transfusion, Omiya Medical Center, Jichi Medical School – sequence: 1 fullname: Henmi, Junko organization: Department of Blood Transfusion, Omiya Medical Center, Jichi Medical School – sequence: 1 fullname: Fujino, Shinji organization: Department of Blood Transfusion, Omiya Medical Center, Jichi Medical School |
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| References | 4) Gibson, J. S., Leff, R. D., Roberts, R. J.: Effects of intravenous delivery systems on infused red blood cells. Am. J. Hosp. Pharm., 41: 468-472, 1984. 2) Clarke, B. S.: A Method for Occult blood in Faeces using Non-carcinogenic Reagents. Med. Lab. Technol., 28: 187-190, 1971. 8) Sowemimo-Coker, S. O.: Red blood cell hemolysis during processing. Transfus. Med. Rev., 16: 46-60, 2002. 3) 関口光夫: イオン選択電極法. 検査と技術, 17: 1167-1172, 1989. 10) Gambino, C., Craig, D., Stiles, M., Dariotis, J.: The effects of Pall RC-50 filtration under pressure on red cell hemolysis. Transfusion, 32 (suppl): 27S, 1992. 5) 岡本好雄, 他: 赤血球用白血球除去フィルターの性能評価の継時的検討の必要性. 日輸血会誌, 45: 238, 1999. 1) 古澤康一: ミッドプレス方式による輸液ポンプの開発. Clin. Engin., 9: 1134-1140, 1998. 6) Burch, K. J., Phelps, S. J., Constance, T. D.: Effect of an infusion device on the integrity of whole blood and packed red blood cells. A. J. Hosp. Pharm., 48: 92-97, 1991. 11) Gammon, R. R., Strayer, S. A., Avery, N. L., Mintz, P. D.: Hemolysis during leukocyte-reduction filtration of stored red blood cells. Ann. Clin. Lab. Sci., 30: 195-199, 2000. 7) 柴雅之, 他: MAP加濃厚赤血球の製造と長期保存試験. 日輸血会誌, 37: 404-410, 1991. 9) Usry, R. T., Moore, G. L., Manalo, F. W.: Morphology of stored, rejuvenated human erythrocytes. Vox Sang., 28: 176-183, 1975. |
| References_xml | – reference: 3) 関口光夫: イオン選択電極法. 検査と技術, 17: 1167-1172, 1989. – reference: 5) 岡本好雄, 他: 赤血球用白血球除去フィルターの性能評価の継時的検討の必要性. 日輸血会誌, 45: 238, 1999. – reference: 11) Gammon, R. R., Strayer, S. A., Avery, N. L., Mintz, P. D.: Hemolysis during leukocyte-reduction filtration of stored red blood cells. Ann. Clin. Lab. Sci., 30: 195-199, 2000. – reference: 1) 古澤康一: ミッドプレス方式による輸液ポンプの開発. Clin. Engin., 9: 1134-1140, 1998. – reference: 4) Gibson, J. S., Leff, R. D., Roberts, R. J.: Effects of intravenous delivery systems on infused red blood cells. Am. J. Hosp. Pharm., 41: 468-472, 1984. – reference: 10) Gambino, C., Craig, D., Stiles, M., Dariotis, J.: The effects of Pall RC-50 filtration under pressure on red cell hemolysis. Transfusion, 32 (suppl): 27S, 1992. – reference: 2) Clarke, B. S.: A Method for Occult blood in Faeces using Non-carcinogenic Reagents. Med. Lab. Technol., 28: 187-190, 1971. – reference: 7) 柴雅之, 他: MAP加濃厚赤血球の製造と長期保存試験. 日輸血会誌, 37: 404-410, 1991. – reference: 6) Burch, K. J., Phelps, S. J., Constance, T. D.: Effect of an infusion device on the integrity of whole blood and packed red blood cells. A. J. Hosp. Pharm., 48: 92-97, 1991. – reference: 8) Sowemimo-Coker, S. O.: Red blood cell hemolysis during processing. Transfus. Med. Rev., 16: 46-60, 2002. – reference: 9) Usry, R. T., Moore, G. L., Manalo, F. W.: Morphology of stored, rejuvenated human erythrocytes. Vox Sang., 28: 176-183, 1975. |
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| Title | LEUKOCYTE REDUCTION FILTERS AND INFUSION DEVICE FOR RED BLOOD CELL TRANSFUSION |
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