Indian clinical practice consensus guidelines for the management of nasopharyngeal cancer: Update 2022
Patients with early-stage nasopharyngeal cancer are treated with definitive radiotherapy alone, including both sides of the neck and retropharyngeal nodes. For patients with locoregionally advanced nasopharyngeal cancer, the recommendation is concurrent chemoradiotherapy with additional chemotherapy...
Saved in:
Published in | Cancer research, statistics, and treatment (Online) Vol. 7; no. Suppl 1; pp. S27 - S30 |
---|---|
Main Authors | , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
India
Wolters Kluwer - Medknow
01.01.2024
|
Edition | 2 |
Subjects | |
Online Access | Get full text |
ISSN | 2590-3233 2590-3225 |
DOI | 10.4103/crst.crst_123_23 |
Cover
Abstract | Patients with early-stage nasopharyngeal cancer are treated with definitive radiotherapy alone, including both sides of the neck and retropharyngeal nodes. For patients with locoregionally advanced nasopharyngeal cancer, the recommendation is concurrent chemoradiotherapy with additional chemotherapy (either before or after chemoradiotherapy). Adding targeted therapies like nimotuzumab to concurrent chemoradiation in the management of nasopharyngeal cancer has been shown to improve overall survival with excellent safety and tolerability. |
---|---|
AbstractList | Patients with early-stage nasopharyngeal cancer are treated with definitive radiotherapy alone, including both sides of the neck and retropharyngeal nodes. For patients with locoregionally advanced nasopharyngeal cancer, the recommendation is concurrent chemoradiotherapy with additional chemotherapy (either before or after chemoradiotherapy). Adding targeted therapies like nimotuzumab to concurrent chemoradiation in the management of nasopharyngeal cancer has been shown to improve overall survival with excellent safety and tolerability. |
Author | Goyal, Sumit Noronha, Vanita John, Subashini Ramachandra, Prakash Birur, Praveen Syiemlieh, Judita Chaturvedi, Pankaj Mahajan, Abhishek Roshan, Vikas Babu, K Govind Patil, Vijay M. Gairola, Munish Anand, Anil K. Prabhash, Kumar Singhal, Manish Kaushal, Ashish Rath, G.K. Kuriakose, Moni Nayyar, Rohit Rao, Vishal |
Author_xml | – sequence: 1 givenname: Munish surname: Gairola fullname: Gairola, Munish – sequence: 2 givenname: Kumar surname: Prabhash fullname: Prabhash, Kumar – sequence: 3 givenname: K Govind surname: Babu fullname: Babu, K Govind – sequence: 4 givenname: Pankaj surname: Chaturvedi fullname: Chaturvedi, Pankaj – sequence: 5 givenname: Moni surname: Kuriakose fullname: Kuriakose, Moni – sequence: 6 givenname: Praveen surname: Birur fullname: Birur, Praveen – sequence: 7 givenname: Anil K. surname: Anand fullname: Anand, Anil K. – sequence: 8 givenname: Ashish surname: Kaushal fullname: Kaushal, Ashish – sequence: 9 givenname: Abhishek surname: Mahajan fullname: Mahajan, Abhishek – sequence: 10 givenname: Judita surname: Syiemlieh fullname: Syiemlieh, Judita – sequence: 11 givenname: Manish surname: Singhal fullname: Singhal, Manish – sequence: 12 givenname: Prakash surname: Ramachandra fullname: Ramachandra, Prakash – sequence: 13 givenname: Sumit surname: Goyal fullname: Goyal, Sumit – sequence: 14 givenname: Subashini surname: John fullname: John, Subashini – sequence: 15 givenname: Rohit surname: Nayyar fullname: Nayyar, Rohit – sequence: 16 givenname: Vijay M. surname: Patil fullname: Patil, Vijay M. – sequence: 17 givenname: Vishal surname: Rao fullname: Rao, Vishal – sequence: 18 givenname: Vanita surname: Noronha fullname: Noronha, Vanita – sequence: 19 givenname: Vikas surname: Roshan fullname: Roshan, Vikas – sequence: 20 givenname: G.K. surname: Rath fullname: Rath, G.K. |
BookMark | eNp9kEtLAzEQgINUsNbePeYPtGaTTbfrTYqPQsGD9hxmk9k2dDdZkpTiv3drVUTQyzyY-YbhuyQD5x0Scp2xaZ4xcaNDTNNjUBkXioszMuSyZBPBuRx810JckHGMtmJ5XgguhRySeumMBUd1Y53V0NAugE5WI9XeRXRxH-lmbw32c4y09oGmLdIWHGywRZeor6mD6LsthDe3wf6EBqcx3NJ1ZyAh5YzzK3JeQxNx_JlHZP1w_7p4mqyeH5eLu9VEZ-WsmRjIIBeyrOVMZxUUeTlnTEjJWaXFnJfc1JnJeWUKnPcLJUoG0PeIlTSlLsWIsNNdHXyMAWvVBdv2n6mMqaMq9WHph6oemf1CtE2QrHcpgG3-A5cn8OCbhCHumv0Bg2rR7Jw__MmpF16ok3X1ZV28A1UVkBY |
CitedBy_id | crossref_primary_10_4103_crst_crst_118_23 |
Cites_doi | 10.1200/JCO.2017.35.15_suppl.6006 10.1016/j.oraloncology.2015.11.019 10.1016/S1470-2045(16)30410-7 10.2147/OTT.S141538 10.1056/NEJMoa1905287 10.3389/fonc.2019.00464 10.1001/jamaoncol.2022.0122 10.1371/journal.pone.0153498 10.4103/ijc.IJC_287_17 10.3389/fonc.2018.00597 10.1016/S1470-2045(15)70126-9 10.1002/cncr.29208 10.1016/S1470-2045(11)70320-5 10.1200/JCO.2016.67.4119 10.4103/2278-330x.214578 10.1007/s12105-014-0528-6 10.1016/j.tranon.2017.11.002 10.3389/fonc.2020.585046 |
ContentType | Journal Article |
Copyright | Copyright: © 2024 Cancer Research, Statistics, and Treatment |
Copyright_xml | – notice: Copyright: © 2024 Cancer Research, Statistics, and Treatment |
DBID | AAYXX CITATION |
DOI | 10.4103/crst.crst_123_23 |
DatabaseName | CrossRef |
DatabaseTitle | CrossRef |
DatabaseTitleList | CrossRef |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 2590-3225 |
Edition | 2 |
EndPage | S30 |
ExternalDocumentID | 10_4103_crst_crst_123_23 CRSAT-7-S27 |
GroupedDBID | ALMA_UNASSIGNED_HOLDINGS GROUPED_DOAJ OK1 OVD RMW TEORI W3E AAYXX ADJBI CITATION |
ID | FETCH-LOGICAL-c196l-da1a4359f56c1ba74980035520bc38292df1d42bd7e8c1b9e50aa42beeb5d9c93 |
IEDL.DBID | W3E |
ISSN | 2590-3233 |
IngestDate | Tue Jul 01 03:54:05 EDT 2025 Thu Apr 24 22:59:50 EDT 2025 Wed May 28 23:14:07 EDT 2025 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | Suppl 1 |
Keywords | Indian guidelines nasopharyngeal cancer chemotherapy recommendations Chemoradiation |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c196l-da1a4359f56c1ba74980035520bc38292df1d42bd7e8c1b9e50aa42beeb5d9c93 |
OpenAccessLink | https://doi.org/10.4103/crst.crst_123_23 |
ParticipantIDs | crossref_primary_10_4103_crst_crst_123_23 crossref_citationtrail_10_4103_crst_crst_123_23 wolterskluwer_medknow_10_4103_crst_crst_123_23_S27_Indian_clinical |
ProviderPackageCode | CITATION AAYXX |
PublicationCentury | 2000 |
PublicationDate | 20240100 2024-01-00 |
PublicationDateYYYYMMDD | 2024-01-01 |
PublicationDate_xml | – month: 01 year: 2024 text: 20240100 |
PublicationDecade | 2020 |
PublicationPlace | India |
PublicationPlace_xml | – name: India |
PublicationTitle | Cancer research, statistics, and treatment (Online) |
PublicationYear | 2024 |
Publisher | Wolters Kluwer - Medknow |
Publisher_xml | – name: Wolters Kluwer - Medknow |
References | Li (R20-20240828) 2022; 8 Liu (R16-20240828) 2018; 8 Haleshappa (R9-20240828) 2017; 6 Ribassin-Majed (R8-20240828) 2017; 35 Lee (R18-20240828) 2015; 121 Li (R4-20240828) 2017; 10 Kunheri (R5-20240828) 2017; 54 Chen (R6-20240828) 2012; 13 Zhang (R19-20240828) 2019; 381 Szturz (R15-20240828) 2019; 9 Lewis (R1-20240828) 2014; 8 R3-20240828 Sun (R11-20240828) 2022; 40 Blanchard (R10-20240828) 2015; 16 Banko (R2-20240828) 2016; 11 Su (R13-20240828) 2021; 10 Sun (R17-20240828) 2016; 17 Ahn (R14-20240828) 2016; 53 Yuan (R12-20240828) 2017; 22 Wang (R21-20240828) 2018; 11 Liang (R7-20240828) 2017; 35 |
References_xml | – volume: 35 start-page: 6006. year: 2017 ident: R7-20240828 article-title: Concurrent chemoradiotherapy with 3-weekly versus weekly cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: A phase 3 multicenter randomized controlled trial (ChiCTR-TRC-12001979) publication-title: J Clin Oncol doi: 10.1200/JCO.2017.35.15_suppl.6006 – volume: 22 start-page: 1004 year: 2017 ident: R12-20240828 article-title: Cetuximab versus nimotuzumab for the treatment of advanced nasopharyngeal carcinoma: A network meta-analysis publication-title: J BUON – volume: 53 start-page: 10 year: 2016 ident: R14-20240828 article-title: Clinical recommendations for defining platinum unsuitable head and neck cancer patient populations on chemoradiotherapy: A literature review publication-title: Oral Oncol doi: 10.1016/j.oraloncology.2015.11.019 – volume: 17 start-page: 1509 year: 2016 ident: R17-20240828 article-title: Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: A phase 3, multicentre, randomized controlled trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(16)30410-7 – volume: 10 start-page: 5445 year: 2017 ident: R4-20240828 article-title: Nimotuzumab combined with concurrent chemoradiotherapy benefits patients with advanced nasopharyngeal carcinoma publication-title: Onco Targets Ther doi: 10.2147/OTT.S141538 – volume: 381 start-page: 1124 year: 2019 ident: R19-20240828 article-title: Gemcitabine and cisplatin induction chemotherapy in nasopharyngeal carcinoma publication-title: N Engl J Med doi: 10.1056/NEJMoa1905287 – ident: R3-20240828 article-title: Guideline Version 2.2019 publication-title: Head and neck cancers – volume: 9 start-page: 464. year: 2019 ident: R15-20240828 article-title: Cisplatin eligibility issues and alternative regimens in locoregionally advanced head and neck cancer: Recommendations for clinical practice publication-title: Front Oncol doi: 10.3389/fonc.2019.00464 – volume: 8 start-page: 706 year: 2022 ident: R20-20240828 article-title: Effect of induction chemotherapy with paclitaxel, cisplatin, and capecitabine vs cisplatin and fluorouracil on failure-free survival for patients with stage IVA to IVB nasopharyngeal carcinoma a multicenter phase 3 randomized clinical trial publication-title: JAMA Oncol doi: 10.1001/jamaoncol.2022.0122 – volume: 11 start-page: e0153498. year: 2016 ident: R2-20240828 article-title: Characterization of the variability of Epstein-Barr virus genes in nasopharyngeal biopsies: Potential predictors for carcinoma progression publication-title: PLoS One doi: 10.1371/journal.pone.0153498 – volume: 54 start-page: 502 year: 2017 ident: R5-20240828 article-title: Nasopharyngeal carcinoma: Experience and treatment outcome with radical conformal radiotherapy from a tertiary care center in India publication-title: Indian J Cancer doi: 10.4103/ijc.IJC_287_17 – volume: 8 start-page: 597. year: 2018 ident: R16-20240828 article-title: The changing role of chemotherapy in locoregionally advanced nasopharyngeal carcinoma: An updated systemic review and network meta-analysis publication-title: Front Oncol doi: 10.3389/fonc.2018.00597 – volume: 16 start-page: 645 year: 2015 ident: R10-20240828 article-title: Chemotherapy and radiotherapy in nasopharyngeal carcinoma: An update of the MAC-NPC meta-analysis publication-title: Lancet Oncol doi: 10.1016/S1470-2045(15)70126-9 – volume: 121 start-page: 1328 year: 2015 ident: R18-20240828 article-title: Preliminary results of trial NPC-0501 evaluating the therapeutic gain by changing from concurrent-adjuvant to induction-concurrent chemoradiotherapy, changing from fluorouracil to capecitabine, and changing from conventional to accelerated radiotherapy fractionation in patients with locoregionally advanced nasopharyngeal carcinoma publication-title: Cancer doi: 10.1002/cncr.29208 – volume: 13 start-page: 163 year: 2012 ident: R6-20240828 article-title: Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: A phase 3 multicenter randomized controlled trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(11)70320-5 – volume: 35 start-page: 498 year: 2017 ident: R8-20240828 article-title: What is the best treatment of locally advanced nasopharyngeal carcinoma? An individual patient data network meta-analysis publication-title: J Clin Oncol doi: 10.1200/JCO.2016.67.4119 – volume: 40 issue: suppl 6001 year: 2022 ident: R11-20240828 article-title: Nimotuzumab plus chemoradiotherapy versus placebo plus chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma (NPC): A prospective, randomized-controlled, double-blinded, multicenter phase III clinical trial publication-title: J Clin Oncol – volume: 6 start-page: 122 year: 2017 ident: R9-20240828 article-title: Epidemiology and outcomes of nasopharyngeal carcinoma: Experience from a regional cancer center in Southern India publication-title: South Asian J Cancer doi: 10.4103/2278-330x.214578 – volume: 8 start-page: 50 year: 2014 ident: R1-20240828 article-title: Human papilloma virus and Epstein Barr virus in head and neck carcinomas: Suggestions for the new WHO classification publication-title: Head Neck Pathol doi: 10.1007/s12105-014-0528-6 – volume: 11 start-page: 65 year: 2018 ident: R21-20240828 article-title: Treatment outcomes of 257 patients with locoregionally advanced nasopharyngeal carcinoma treated with nimotuzumab plus intensity-modulated radiotherapy with or without chemotherapy: A single-institution experience publication-title: Transl Oncol doi: 10.1016/j.tranon.2017.11.002 – volume: 10 start-page: 585046. year: 2021 ident: R13-20240828 article-title: The current role of adjuvant chemotherapy in locally advanced nasopharyngeal carcinoma publication-title: Front Oncol doi: 10.3389/fonc.2020.585046 |
SSID | ssib044732535 ssj0002511772 ssib053799620 |
Score | 2.2466002 |
Snippet | Patients with early-stage nasopharyngeal cancer are treated with definitive radiotherapy alone, including both sides of the neck and retropharyngeal nodes. For... |
SourceID | crossref wolterskluwer |
SourceType | Enrichment Source Index Database Publisher |
StartPage | S27 |
SubjectTerms | Special Article |
Title | Indian clinical practice consensus guidelines for the management of nasopharyngeal cancer: Update 2022 |
URI | https://doi.org/10.4103/crst.crst_123_23 |
Volume | 7 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1JS8QwFA4uIIKIK44bOXjxUKfN0rTeVEZEGC866C0kaepBpzPMgnjxt_tel3EE9eQlUEha-PKa9-WthJxkxmapdSpQhsEFBU1WiZQ8yCXzMY-slWUlpu5dfNMTt0_yqbZ3YC7MnP9eRCFvO-BAZzhoOGI144tkmakoRfl95J1GcoRQnMkvxS-5Ah5fEyE8k5FIq7KTE9B9OHgY55XP8sePfNNRa28D9FuPX8qw9Tnlc71B1mvWSC-qbd4kC77YIivd2i--TbADB-wzbfIcaZP8RB1GSxfj6Zg-T7GiFUa5UyCqFIgf7c9iX-ggp4XBlgZm9F48A3ukDuVhdE57QzQKUAZqeIf0rjsPVzdB3UEhcPBnvQaZiQzwoTSXsYusUSJN0HUoWWgdT1jKsjzKBLOZ8glMSL0MjYFn763MUpfyXbJUDAq_RygQP56EluW5MMLa0GAvBOkNE3FulVct0m4w064uL45dLl41XDMQZV0CPIdyi5zOVgyr0hp_zL38tg26XyUL_rpA3zOlK-x1g_3-f7zkgKwC4KKywhySpclo6o-Al0zscXmfh7H70TkuxfMThFzkzA |
linkProvider | Wolters Kluwer Health |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Indian+clinical+practice+consensus+guidelines+for+the+management+of+nasopharyngeal+cancer%3A+Update+2022&rft.jtitle=Cancer+research%2C+statistics%2C+and+treatment+%28Online%29&rft.au=Gairola%2C+Munish&rft.au=Prabhash%2C+Kumar&rft.au=Babu%2C+K+Govind&rft.au=Chaturvedi%2C+Pankaj&rft.date=2024-01-01&rft.issn=2590-3233&rft.eissn=2590-3225&rft.volume=7&rft.issue=Suppl+1&rft.spage=S27&rft.epage=S30&rft_id=info:doi/10.4103%2Fcrst.crst_123_23&rft.externalDBID=n%2Fa&rft.externalDocID=10_4103_crst_crst_123_23 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2590-3233&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2590-3233&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2590-3233&client=summon |