Study on the Effect of Vitamin C Intake on the Serum Glutamic Pyruvic Transaminase (SGPT) Activity in Man

The effect of the vitamicn C intake on serum SGPT activity was examined. The results are as follows. 1) In an epidemiological study, significant correlaiton was found between SGPT activity and serum vitamin C in 76 healthy young volunteers (y=-18.7x + 19.2, r=-0.383). 2) In a laboratory study, we ad...

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Published inJapanese Journal of Health and Human Ecology Vol. 54; no. 4; pp. 184 - 192
Main Authors YOSHIMURA, Takeshi, TANADA, Seiki, IMAKI, Masahide, MATSUMOTO, Kazuoki, SEI, Masako, MIYOSHI, Tamotus
Format Journal Article
LanguageEnglish
Published The Japanese Society of Health and Human Ecology 1988
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ISSN0368-9395
1882-868X
1882-868X
DOI10.3861/jshhe.54.184

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Abstract The effect of the vitamicn C intake on serum SGPT activity was examined. The results are as follows. 1) In an epidemiological study, significant correlaiton was found between SGPT activity and serum vitamin C in 76 healthy young volunteers (y=-18.7x + 19.2, r=-0.383). 2) In a laboratory study, we administered vitamin C at dose of 1 g/day for 10 days and then at a dose of 10 g/day for 10 days to five subjects, but found not significant different between SGPT activity before and after treatment. 3) We administered vitamin C at dose of 1 g/day for 1 year, but found not significant different between SGPT activity before and after treatment.
AbstractList The effect of the vitamicn C intake on serum SGPT activity was examined. The results are as follows. 1) In an epidemiological study, significant correlaiton was found between SGPT activity and serum vitamin C in 76 healthy young volunteers (y=-18.7x + 19.2, r=-0.383). 2) In a laboratory study, we administered vitamin C at dose of 1 g/day for 10 days and then at a dose of 10 g/day for 10 days to five subjects, but found not significant different between SGPT activity before and after treatment. 3) We administered vitamin C at dose of 1 g/day for 1 year, but found not significant different between SGPT activity before and after treatment.
Author MIYOSHI, Tamotus
TANADA, Seiki
SEI, Masako
IMAKI, Masahide
YOSHIMURA, Takeshi
MATSUMOTO, Kazuoki
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  organization: Department of Public Health , School of Medicine, The University of Tokushima
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  fullname: IMAKI, Masahide
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  fullname: MATSUMOTO, Kazuoki
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  fullname: SEI, Masako
  organization: Department of Public Health , School of Medicine, The University of Tokushima
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  fullname: MIYOSHI, Tamotus
  organization: Department of Public Health , School of Medicine, The University of Tokushima
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References Edozin, J.C. (1960) : Enzymes in serum in Kwashiorkor, Pediatrics, 27, 325-330
Haward, CE. (!)(") : Effects of vitamin C loading on serum constituents in man, Pro. Soc. Exp. Bio. Med., 169, 363-367
Ayekyaw (1978) : A simple colorimetric method for ascorbic acid determination in blood plasma, Clin. Chim. Acta, 86, 153-157
北村元仕(1985):血清酵素の異常,9-11,医学書院(東京)
Garry, P.J., Goodwin, J.S., Hunt, W.C. & Gilbert, B.A. (1982) : Nutritional status in a healthy elderly population vitamin C, Am. J. Clin. Nutr., 36, 332-339
Takeda, Y. (1964) : The biochemistry of cell 1. The effects of corticosterods on leakage of enzymes from dispersed rat liver cells, J. Biol. Chem., 239, 3590-3596
牧野秀夫(1984):栄養アセスメントと臨床検査,臨床検査,28(13),171-1748
Bate, J.C., Ingrid, H.E., Black, A.E. & Paul, A.A. (1979) : Long-term vitamin status and dietary intake of healthy elderly subjects. 2. Vitamin C, Br. J. Nutr., 42, 43-56
林 康之,加藤沢信彦,香川芳子,浅野牧茂(1982):食:事,飲酒,喫煙と検査データ,臨床検査,26,68-77
田村善蔵,織田敏次(1970):血清酵素,14-33,医学書院(東京)
Giltlin, N. (1982) : The serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase ratio as a prognostic index in sever acute viral hepatitis, Amer. J. Med., 77, 2-4
Karmen, A. (1955): A note on the spectrophotometric assay of glutamic oxalacetic transaminase in human blood serum, J. Clin. Invest., 34, 131-133
Steiteghem, A. (1978) : Influence of large doses of ascorbic acid on laboratory test, Clin. Chem., 24(1), 54-57
Wroblwski, G. & La Due, S.J. (1956) : Serum glutamic pyruvic transaminase in gardiac and hepatic disease, Proc. Soc. Exp. Biol. Med., 91, 571-596
今木雅英,三好 保:血清酵素活性値の栄養学的評価に関する研究,日本公衛誌,31(5),193-198
References_xml – reference: 北村元仕(1985):血清酵素の異常,9-11,医学書院(東京)
– reference: Ayekyaw (1978) : A simple colorimetric method for ascorbic acid determination in blood plasma, Clin. Chim. Acta, 86, 153-157
– reference: Bate, J.C., Ingrid, H.E., Black, A.E. & Paul, A.A. (1979) : Long-term vitamin status and dietary intake of healthy elderly subjects. 2. Vitamin C, Br. J. Nutr., 42, 43-56
– reference: 田村善蔵,織田敏次(1970):血清酵素,14-33,医学書院(東京)
– reference: Wroblwski, G. & La Due, S.J. (1956) : Serum glutamic pyruvic transaminase in gardiac and hepatic disease, Proc. Soc. Exp. Biol. Med., 91, 571-596
– reference: 今木雅英,三好 保:血清酵素活性値の栄養学的評価に関する研究,日本公衛誌,31(5),193-198
– reference: 林 康之,加藤沢信彦,香川芳子,浅野牧茂(1982):食:事,飲酒,喫煙と検査データ,臨床検査,26,68-77
– reference: Karmen, A. (1955): A note on the spectrophotometric assay of glutamic oxalacetic transaminase in human blood serum, J. Clin. Invest., 34, 131-133
– reference: Takeda, Y. (1964) : The biochemistry of cell 1. The effects of corticosterods on leakage of enzymes from dispersed rat liver cells, J. Biol. Chem., 239, 3590-3596
– reference: Giltlin, N. (1982) : The serum glutamic oxaloacetic transaminase/serum glutamic pyruvic transaminase ratio as a prognostic index in sever acute viral hepatitis, Amer. J. Med., 77, 2-4
– reference: 牧野秀夫(1984):栄養アセスメントと臨床検査,臨床検査,28(13),171-1748
– reference: Steiteghem, A. (1978) : Influence of large doses of ascorbic acid on laboratory test, Clin. Chem., 24(1), 54-57
– reference: Edozin, J.C. (1960) : Enzymes in serum in Kwashiorkor, Pediatrics, 27, 325-330
– reference: Garry, P.J., Goodwin, J.S., Hunt, W.C. & Gilbert, B.A. (1982) : Nutritional status in a healthy elderly population vitamin C, Am. J. Clin. Nutr., 36, 332-339
– reference: Haward, CE. (!)(") : Effects of vitamin C loading on serum constituents in man, Pro. Soc. Exp. Bio. Med., 169, 363-367
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Title Study on the Effect of Vitamin C Intake on the Serum Glutamic Pyruvic Transaminase (SGPT) Activity in Man
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