Prevalence of Periodontopathic Bacteria in Healthy Subjects and Adult Periodontitis Patients in China (Beijing)
This study used the polymerase chain reaction to investigate the prevalence of 7 putative periodontopathic bacteria in 20 periodontally healthy subjects (33. 5±7. 0 years old) and 21 adult periodontitis patients 44. 8±12. 0 years old) in China Beijing). Subgingival specimens were collected with a pa...
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| Published in | Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) Vol. 45; no. 2; pp. 163 - 170 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | Japanese |
| Published |
JAPANESE SOCIETY OF PERIODONTOLOGY
2003
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0385-0110 1880-408X 1880-408X |
| DOI | 10.2329/perio.45.163 |
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| Abstract | This study used the polymerase chain reaction to investigate the prevalence of 7 putative periodontopathic bacteria in 20 periodontally healthy subjects (33. 5±7. 0 years old) and 21 adult periodontitis patients 44. 8±12. 0 years old) in China Beijing). Subgingival specimens were collected with a paper point (from subgingival sites in healthy subjects (n= 20) and from healthy (n=16) and from diseased subgingival sites n= 21) in adult periodontitis patients. Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, and Prevotella intermedia were frequently detected (from 85% to 95%) in the diseased sites of patients, and 3 species, Prevotella nigrescens, Prevotella pallens, and Actinobacillus actinomycetemcomitans, were moderately detected (from 24% to 33%). The distribution patterns of the 7 bacterial species were analyzed by Fisher's direct method. P. gingivalis, T. forsythensis, T. denticola, and P. intermedia showed a significantly similar pattern in the sampling sites (p<0. 0001), and they formed complex. P. nigrescens, P. Miens, and A. actinomycetemcomitans showed patterns that were partially similar to that of the above 4 species, and they formed four independent groups. In contrast to P. nigrescens, P. intermedia seemed to be an important etiogenic periodontopathogen, the same as P. gingivalis, T. forsythensis, and T. denticola. J Jpn Soc Periodontol, 45 : 163-170, 2003. |
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| AbstractList | This study used the polymerase chain reaction to investigate the prevalence of 7 putative periodontopathic bacteria in 20 periodontally healthy subjects (33. 5±7. 0 years old) and 21 adult periodontitis patients 44. 8±12. 0 years old) in China Beijing). Subgingival specimens were collected with a paper point (from subgingival sites in healthy subjects (n= 20) and from healthy (n=16) and from diseased subgingival sites n= 21) in adult periodontitis patients. Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola, and Prevotella intermedia were frequently detected (from 85% to 95%) in the diseased sites of patients, and 3 species, Prevotella nigrescens, Prevotella pallens, and Actinobacillus actinomycetemcomitans, were moderately detected (from 24% to 33%). The distribution patterns of the 7 bacterial species were analyzed by Fisher's direct method. P. gingivalis, T. forsythensis, T. denticola, and P. intermedia showed a significantly similar pattern in the sampling sites (p<0. 0001), and they formed complex. P. nigrescens, P. Miens, and A. actinomycetemcomitans showed patterns that were partially similar to that of the above 4 species, and they formed four independent groups. In contrast to P. nigrescens, P. intermedia seemed to be an important etiogenic periodontopathogen, the same as P. gingivalis, T. forsythensis, and T. denticola. J Jpn Soc Periodontol, 45 : 163-170, 2003. |
| Author | Okamoto, Masaaki Maeda, Nobuko |
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| References | Sakamoto M, Suzuki M, Umeda M, Ishikawa I, Benno Y: Reclassification of Bacteroides forsythus (Tanner et al. 1986) as Tannerella forsythensis corrig., gen. nov., comb. nov. Int J Syst Evol Microbiol, 52: 841-849, 2002. Slots J, Contreras A: Herpesviruses: a unifying causative factor in periodontitis? Oral Microbiol Immunol, 15: 277-280, 2000. Hamlet SM, Cullinan MP, Westerman B, Lindeman, Bird PS, Palmer J, Seymour GJ: Distribution of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia in an Australian population. J Clin Periodontol, 28: 1163-1171, 2001. Ashimoto A, Chen C, Bakker I, Slots J: Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol, 11: 266-273, 1996. Tan KS, Woo CH, Ong G, Song KP: Prevalence of Actinobacillus actinomycetemcomitans in an ethnic adult Chinese population. J Clin Periodontol, 28: 886-890, 2001 Sanz M, van Winkelhoff AJ, Herrera D, Dellemijn-Kippuw, N, Simon R, Winkel E: Differences in the composition of the subgingival microbiota of two periodontitis populations of different geographical origin. A comparison between Spain and the Netherlands. Eur J Oral Sci, 108: 383-392, 2000. 藤本淳: 成人型歯周炎におる歯周病関連細菌と臨床的パラメーターとの関連-PCR法による病変部歯肉および歯肉縁下プラークからの検出一. 日歯周誌, 40: 389-399, 1998. Socransky SS, Haffajee AD: Microbial mechanisms in the pathogenesis of destructive periodontal diseases: a critical assessment. J Periodontal Res, 26: 195-212, 1991. Dahlen GG, Luan WM, Baelum V, Fejerskov 0, Chen X: Periodontopathogens in elderly Chinese with different periodontal disease experience. J Clin Periodontol, 22: 188-200, 1995. Socransky SS, Haffajee AD, 6C) ugini MA, Smith C, Kent RL Jr: Microbial complexes in subgingival plaque. J Clin Periodontol, 25: 134-144, 1998. Silness J, Loe H: Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand, 22: 121-135, 1966. Maeda N, Okamoto M, Kondo K, Ishikawa H, Osada R, Tsurumoto A, Fujita H: Incidence of Prevotella intermedia and Prevotella nigrescens in periodontal health and disease. Microbiol Immunol, 42: 583-589, 1998. Timmerman MF, Van der Weijden GA, Arief EM, Armand S, Abbas F, Winkel EG, Van Winkelhoff AJ, Van der Velden U: Untreated periodontal disease in Indonesian adolescents. Subgingival microbiota in relation to experienced progression of periodontitis. J Clin Periodontol, 28: 617-627, 2001. Sirinian G, Shimizu T, Sugar C, Slots J, Chen C: Periodontopathic bacteria in young healthy subjects of different ethnic backgrounds in Los Angeles. J Periodontol, 73: 283-288, 2002. Goncharoff P, Figurski DH, Stevens RH, Fine DH: Identification of Actinobacillus actinomycetemcomitans: polymerase chain reaction amplification of lktA-specific sequences. Oral Microbiol Immunol, 8: 105-110, 1993. Lopez NJ, Mellado JC, Giglio MS, Leighton GX: Occurrence of certain bacterial species and morphotypes in juvenile periodontitis in Chile. J Periodontol, 66: 559-567, 1995. Lbe H, Silness J: Periodontal disease in pregnancy. 1. Prevalence and severity. Acta Odontol Scand, 21: 533-551, 1963. Mombelli A, Gmiir R, Lang NP, Corbert E, Frey J: Actinobacillus actinomycetemcomitans in Chinese adults. Serotype distribution and analysis of the leukotoxin gene promoter locus. J Clin Periodontol, 26: 505-510, 1999. Choi BK, Park SH, Yoo YJ, Choi SH, Chai JK, Cho KS, Kim CK: Detection of major putative periodontopathogens in Korean advanced adult periodontitis patients using a nucleic acid-based approach. J Periodontol, 71: 1387-1394, 2000. KOnOnen E, Wolf J, MattO J, Frandsen EV, Poulsen K, Jousimies-Somer H, Asikainen S: The Prevotella intermedia group organisms in young children and their mothers as related to maternal periodontal status. J Periodontal Res, 35: 329-334, 2000. Baumgartner JC, Bae KS, Xia T, Whitt J, David LL: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and polymerase chain reaction for differentiation of Prevotella intermedia and Prevotella nigrescens. J Endod, 25: 324-328, 1999. Forng RY, Champagne C, Simpson W, Genco CA: Environmental cues and gene expression in Porphyrornonas gingivalis and Actinobacillus actinornycetemcomitans. Oral Dis, 6: 351-365, 2000. Ali RW, Johannessen AC, Dahlen G, Socransky SS, Skaug N: Comparison of the subgingival microbiota of periodontally healthy and diseased adults in northern Cameroon. J Clin Periodontol, 24: 830-835, 1997. Umeda M, Chen C, Bakker I, Contreras A, Morrison JL, Slots J: Risk indicators for harboring periodontal pathogens. J Periodontol, 69: 1111-1118, 1998. Lotufo RF, Flynn J, Chen C, Slots J: Molecular detection of Bacteroides forsythus in human periodontitis. Oral Microbiol Immunol, 9: 154-160, 1994. Okamoto M, Takano K, Maeda N: Distribution of the tetracycline resistance determinant tetQ gene in oral isolates of black-pigmented anaerobes in Japan. Oral Microbiol Immunol, 16: 224-228, 2001. Contreras A, Rusitanonta T, Chen C, Wagner WG, Michalowicz BS, Slots J: Frequency of 530-bp deletion in Actinobacillus actinomycetemcomitans leukotoxin promoter region. Oral Microbiol Immunol, 15: 338-340, 2000. Grossi SG, Zambon JJ, Ho AW, Koch G, Dunford RG, Machtei EE, Norderyd OM, Genco RJ: Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol, 65: 260-267, 1994. Papapanou PN, Baelum V, Luan WM, Madianos PN, Chen X, Fejerskov 0, Dahlen GG: Subgingival microbiota in adult Chinese: prevalence and relation to periodontal disease progression. J Periodontol, 68: 651-666, 1997. Yano-Higuchi K, Takamatsu N, He T, Umeda M, Ishikawa I: Prevalence of Bacteroides forsythus, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival microflora of Japanese patients with adult and rapidly progressive periodontitis. J Clin Periodontol, 27 : 597-602, 2000 Shah HN, Gharbia SE: Biochemical and chemical studies on strains designated Prevotella intermedia and proposal of a new pigmented species, Prevotella nigrescens sp. nov. Int J Syst Bacteriol, 42: 542-546, 1992. |
| References_xml | – reference: Sanz M, van Winkelhoff AJ, Herrera D, Dellemijn-Kippuw, N, Simon R, Winkel E: Differences in the composition of the subgingival microbiota of two periodontitis populations of different geographical origin. A comparison between Spain and the Netherlands. Eur J Oral Sci, 108: 383-392, 2000. – reference: Grossi SG, Zambon JJ, Ho AW, Koch G, Dunford RG, Machtei EE, Norderyd OM, Genco RJ: Assessment of risk for periodontal disease. I. Risk indicators for attachment loss. J Periodontol, 65: 260-267, 1994. – reference: Okamoto M, Takano K, Maeda N: Distribution of the tetracycline resistance determinant tetQ gene in oral isolates of black-pigmented anaerobes in Japan. Oral Microbiol Immunol, 16: 224-228, 2001. – reference: Timmerman MF, Van der Weijden GA, Arief EM, Armand S, Abbas F, Winkel EG, Van Winkelhoff AJ, Van der Velden U: Untreated periodontal disease in Indonesian adolescents. Subgingival microbiota in relation to experienced progression of periodontitis. J Clin Periodontol, 28: 617-627, 2001. – reference: Papapanou PN, Baelum V, Luan WM, Madianos PN, Chen X, Fejerskov 0, Dahlen GG: Subgingival microbiota in adult Chinese: prevalence and relation to periodontal disease progression. J Periodontol, 68: 651-666, 1997. – reference: Yano-Higuchi K, Takamatsu N, He T, Umeda M, Ishikawa I: Prevalence of Bacteroides forsythus, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival microflora of Japanese patients with adult and rapidly progressive periodontitis. J Clin Periodontol, 27 : 597-602, 2000 – reference: Choi BK, Park SH, Yoo YJ, Choi SH, Chai JK, Cho KS, Kim CK: Detection of major putative periodontopathogens in Korean advanced adult periodontitis patients using a nucleic acid-based approach. J Periodontol, 71: 1387-1394, 2000. – reference: Lotufo RF, Flynn J, Chen C, Slots J: Molecular detection of Bacteroides forsythus in human periodontitis. Oral Microbiol Immunol, 9: 154-160, 1994. – reference: Socransky SS, Haffajee AD: Microbial mechanisms in the pathogenesis of destructive periodontal diseases: a critical assessment. J Periodontal Res, 26: 195-212, 1991. – reference: Goncharoff P, Figurski DH, Stevens RH, Fine DH: Identification of Actinobacillus actinomycetemcomitans: polymerase chain reaction amplification of lktA-specific sequences. Oral Microbiol Immunol, 8: 105-110, 1993. – reference: Ashimoto A, Chen C, Bakker I, Slots J: Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions. Oral Microbiol Immunol, 11: 266-273, 1996. – reference: Dahlen GG, Luan WM, Baelum V, Fejerskov 0, Chen X: Periodontopathogens in elderly Chinese with different periodontal disease experience. J Clin Periodontol, 22: 188-200, 1995. – reference: Sakamoto M, Suzuki M, Umeda M, Ishikawa I, Benno Y: Reclassification of Bacteroides forsythus (Tanner et al. 1986) as Tannerella forsythensis corrig., gen. nov., comb. nov. Int J Syst Evol Microbiol, 52: 841-849, 2002. – reference: Lopez NJ, Mellado JC, Giglio MS, Leighton GX: Occurrence of certain bacterial species and morphotypes in juvenile periodontitis in Chile. J Periodontol, 66: 559-567, 1995. – reference: Contreras A, Rusitanonta T, Chen C, Wagner WG, Michalowicz BS, Slots J: Frequency of 530-bp deletion in Actinobacillus actinomycetemcomitans leukotoxin promoter region. Oral Microbiol Immunol, 15: 338-340, 2000. – reference: Shah HN, Gharbia SE: Biochemical and chemical studies on strains designated Prevotella intermedia and proposal of a new pigmented species, Prevotella nigrescens sp. nov. Int J Syst Bacteriol, 42: 542-546, 1992. – reference: Mombelli A, Gmiir R, Lang NP, Corbert E, Frey J: Actinobacillus actinomycetemcomitans in Chinese adults. Serotype distribution and analysis of the leukotoxin gene promoter locus. J Clin Periodontol, 26: 505-510, 1999. – reference: Socransky SS, Haffajee AD, 6C) ugini MA, Smith C, Kent RL Jr: Microbial complexes in subgingival plaque. J Clin Periodontol, 25: 134-144, 1998. – reference: Slots J, Contreras A: Herpesviruses: a unifying causative factor in periodontitis? Oral Microbiol Immunol, 15: 277-280, 2000. – reference: KOnOnen E, Wolf J, MattO J, Frandsen EV, Poulsen K, Jousimies-Somer H, Asikainen S: The Prevotella intermedia group organisms in young children and their mothers as related to maternal periodontal status. J Periodontal Res, 35: 329-334, 2000. – reference: Forng RY, Champagne C, Simpson W, Genco CA: Environmental cues and gene expression in Porphyrornonas gingivalis and Actinobacillus actinornycetemcomitans. Oral Dis, 6: 351-365, 2000. – reference: Lbe H, Silness J: Periodontal disease in pregnancy. 1. Prevalence and severity. Acta Odontol Scand, 21: 533-551, 1963. – reference: Baumgartner JC, Bae KS, Xia T, Whitt J, David LL: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and polymerase chain reaction for differentiation of Prevotella intermedia and Prevotella nigrescens. J Endod, 25: 324-328, 1999. – reference: 藤本淳: 成人型歯周炎におる歯周病関連細菌と臨床的パラメーターとの関連-PCR法による病変部歯肉および歯肉縁下プラークからの検出一. 日歯周誌, 40: 389-399, 1998. – reference: Silness J, Loe H: Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand, 22: 121-135, 1966. – reference: Maeda N, Okamoto M, Kondo K, Ishikawa H, Osada R, Tsurumoto A, Fujita H: Incidence of Prevotella intermedia and Prevotella nigrescens in periodontal health and disease. Microbiol Immunol, 42: 583-589, 1998. – reference: Umeda M, Chen C, Bakker I, Contreras A, Morrison JL, Slots J: Risk indicators for harboring periodontal pathogens. J Periodontol, 69: 1111-1118, 1998. – reference: Ali RW, Johannessen AC, Dahlen G, Socransky SS, Skaug N: Comparison of the subgingival microbiota of periodontally healthy and diseased adults in northern Cameroon. J Clin Periodontol, 24: 830-835, 1997. – reference: Tan KS, Woo CH, Ong G, Song KP: Prevalence of Actinobacillus actinomycetemcomitans in an ethnic adult Chinese population. J Clin Periodontol, 28: 886-890, 2001 – reference: Hamlet SM, Cullinan MP, Westerman B, Lindeman, Bird PS, Palmer J, Seymour GJ: Distribution of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia in an Australian population. J Clin Periodontol, 28: 1163-1171, 2001. – reference: Sirinian G, Shimizu T, Sugar C, Slots J, Chen C: Periodontopathic bacteria in young healthy subjects of different ethnic backgrounds in Los Angeles. J Periodontol, 73: 283-288, 2002. |
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| Title | Prevalence of Periodontopathic Bacteria in Healthy Subjects and Adult Periodontitis Patients in China (Beijing) |
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