Risk Evaluation of Poly Aromatic Hydrocarbons and MCF7 Cell Growth Activity at a Landfill Site

Poly aromatic hydrocarbons (PAHs) contained in fly and bottom ash, their leaching characteristics and absorbance into ash and estorogen-like cell growth activity caused by the elution from the ash were investigated in order to evaluate the effect of these ashes on the leachate and the water quality...

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Published inJournal of the Japan Society of Waste Management Experts Vol. 13; no. 6; pp. 370 - 378
Main Authors Kanoh, Saeko, Kenmotsu, Katashi, Okamura, Hideo, Ono, Yoshiro
Format Journal Article
LanguageJapanese
Published Japan Society of Material Cycles and Waste Management 2002
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ISSN1883-1648
1883-163X
DOI10.3985/jswme.13.370

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Abstract Poly aromatic hydrocarbons (PAHs) contained in fly and bottom ash, their leaching characteristics and absorbance into ash and estorogen-like cell growth activity caused by the elution from the ash were investigated in order to evaluate the effect of these ashes on the leachate and the water quality at the site. The leaching of PAHs having less than 4 rings was observed. It was found that these compounds could be absorbed into ashes and sediments. The concentration of PAHs in the leachate was determined to be very low and there was only a trace of the PAHs in the sediments around the outlet of the leachate treatment facility. These compounds were removed through treatment processes with coagulated-sedimentation, biological treatment and sand filtration with activate carbon adsorption. The estrogen like growth activity of MCF7, a human breast cancer cell line, on the PAHs included in bottom ash was about 50% of the theoretical prediction.
AbstractList Poly aromatic hydrocarbons (PAHs) contained in fly and bottom ash, their leaching characteristics and absorbance into ash and estorogen-like cell growth activity caused by the elution from the ash were investigated in order to evaluate the effect of these ashes on the leachate and the water quality at the site. The leaching of PAHs having less than 4 rings was observed. It was found that these compounds could be absorbed into ashes and sediments. The concentration of PAHs in the leachate was determined to be very low and there was only a trace of the PAHs in the sediments around the outlet of the leachate treatment facility. These compounds were removed through treatment processes with coagulated-sedimentation, biological treatment and sand filtration with activate carbon adsorption. The estrogen like growth activity of MCF7, a human breast cancer cell line, on the PAHs included in bottom ash was about 50% of the theoretical prediction.
Author Kenmotsu, Katashi
Okamura, Hideo
Kanoh, Saeko
Ono, Yoshiro
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  fullname: Ono, Yoshiro
  organization: Dept. of Environmental and Civil Engineering, University of Okayama
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References 3) E. Menichini and F. Monfredini: A collaborative study of a method for the determination of polycyclic aromatic hydrocarbons in fly ash from waste incineration, Chemophere, Vol.35, No.10, pp.2389-2404 (1997
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5) A.M. Soto, K.L. Chung and C. Sonnenschein: The pesticides endosulfan, toxaphene and dieldrin have estrogenid effects on human estrogensensitive cells, Environ Health Perspects, No.102, pp.380-383 (1994
4) 環境庁水質保全局水質管理課: 平成11年度水環境中の内分泌攪乱性化学物質実態調査, (2000
7) Y. Nakagawa, T. Suzuki and S. Tayama: Metabolism and toxicity of benzophenoene in isolated rat heptatpcytes and estrogenic activity of its metabosites in MCF-7 cells, Toxicology, No.156, pp.27-36 (2000
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6) A.M. Soto, K.L. Chung, M.F. Fernandez, N. Olea and F.O. Serrsno: The E-screen assay as a tool to identify estrogens: an update on estrogenic environmental pollutants, Environ Health Perspect, No.103, pp.113-122 (1995
8) K.F. Arco, Y. Yang and J.F. Gierthy: Benzo [k] fluoranthne enhancement and suppression of 17-estoradiol catabolism un MCF-7 breast cancer cells, J. of Toxicology and Environmental Health, Vol.58, No.7, pp.413-426 (1999
References_xml – reference: 2) 環境庁環境安全課: 平成10年度化学物質分析法開発調査報告書 (その2) (多環芳香族炭化水素: 岡山県環境保健センター) (2000)
– reference: 7) Y. Nakagawa, T. Suzuki and S. Tayama: Metabolism and toxicity of benzophenoene in isolated rat heptatpcytes and estrogenic activity of its metabosites in MCF-7 cells, Toxicology, No.156, pp.27-36 (2000)
– reference: 1) 環境庁環境安全課: 平成9年度化学物質分析法開発調査報告書 (ベンゾオチフェン, ジベンゾチオフェン等: 岡山県環境保健センター) (1998)
– reference: 4) 環境庁水質保全局水質管理課: 平成11年度水環境中の内分泌攪乱性化学物質実態調査, (2000)
– reference: 5) A.M. Soto, K.L. Chung and C. Sonnenschein: The pesticides endosulfan, toxaphene and dieldrin have estrogenid effects on human estrogensensitive cells, Environ Health Perspects, No.102, pp.380-383 (1994)
– reference: 3) E. Menichini and F. Monfredini: A collaborative study of a method for the determination of polycyclic aromatic hydrocarbons in fly ash from waste incineration, Chemophere, Vol.35, No.10, pp.2389-2404 (1997)
– reference: 8) K.F. Arco, Y. Yang and J.F. Gierthy: Benzo [k] fluoranthne enhancement and suppression of 17-estoradiol catabolism un MCF-7 breast cancer cells, J. of Toxicology and Environmental Health, Vol.58, No.7, pp.413-426 (1999)
– reference: 9) 小野芳朗, 加納佐江子, 青井健太郎, 山田正人, 今岡務, 河原長美: 廃棄物試料のエストロジェン様のMCF7細胞増殖活性・遺伝毒性評価, 廃棄物学会論文誌, 第11巻, 第3号, pp. 126-134 (2000)
– reference: 6) A.M. Soto, K.L. Chung, M.F. Fernandez, N. Olea and F.O. Serrsno: The E-screen assay as a tool to identify estrogens: an update on estrogenic environmental pollutants, Environ Health Perspect, No.103, pp.113-122 (1995)
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SubjectTerms ashes
landfill site
leachate
MCF7 cell
poly aromatic hydrocarbons
Title Risk Evaluation of Poly Aromatic Hydrocarbons and MCF7 Cell Growth Activity at a Landfill Site
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