Regulation of Acupuncture on Interferon-γ and Tumor Necrosis Factor of Lung Cancer-Operative Cases

Objective: To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases.Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immuno-enzymatic method (ELISA); to m...

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Published inJournal of acupuncture and tuina science Vol. 4; no. 4; pp. 230 - 232
Main Author 周红 童稳圃 施伶俐 闵屹华 沈华 韩丑萍(Translator)
Format Journal Article
LanguageEnglish
Published Heidelberg Springer Nature B.V 01.08.2006
上海市肺科医院
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ISSN1672-3597
1993-0399
DOI10.1007/BF02870130

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Abstract Objective: To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases.Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immuno-enzymatic method (ELISA); to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups.Results: The pre-operation INF-γ contents of the two groups showed no significant difference (P>0.05); the post-operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation (P<0.05); the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation (P<0.05); the pre-operation TNF contents of the two groups showed no significant difference (P>0.05) and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation (P<0.05).Conclusion: Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.
AbstractList R2; 目的:探讨肺癌手术患者应用针刺对γ-干扰素(INF-γ)和肿瘤坏死因子(TNF)的调节.方法:采用双抗体夹心免疫酶标法(ELISA)检测肺癌患者血清中INF-γ和肿瘤坏死因子含量;将针药麻组与全麻组肺癌手术患者各30例,分别在术前、术后8日、术后12日测量INF-γ和TNF含量作比较.结果:血清中INF-γ含量在术前作两组比较无明显差异(P>0.05).术后第8日和第12日作两组比较均有显著差异(P<0.05),针药麻组优于全麻组.自身比较针药麻组术后第12日和术后第8日比较有显著差异(P<0.05).血清中肿瘤坏死因子含量在术前作两组比较(P>0.05)无明显差异;在术后第8日及术后第12日作比较(P<0.05)均有显著差异.结论: 肺癌手术患者应用针刺能升高血清中INF-γ和TNF含量,对肺癌手术患者有免疫调节功能.
Objective: To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases.Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immuno-enzymatic method (ELISA); to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups.Results: The pre-operation INF-γ contents of the two groups showed no significant difference (P>0.05); the post-operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation (P<0.05); the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation (P<0.05); the pre-operation TNF contents of the two groups showed no significant difference (P>0.05) and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation (P<0.05).Conclusion: Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.
Abstract_FL Objective:To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases. Methods: to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immuno-enzymatic method (ELISA); to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups. Results:The pre-operation INF-γ contents of the two groups showed no significant difference (P>0.05); the post-operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation (P<0.05); the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation (P<0.05); the pre-operation TNF contents of the two groups showed no significant difference (P>0.05) and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation (P<0.05). Conclusion:Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.
Author 周红 童稳圃 施伶俐 闵屹华 沈华 韩丑萍(Translator)
AuthorAffiliation 上海市肺科医院
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Issue 4
Keywords γ-interferon II
Lung Cancer
Combined Acupuncture and Drug Anesthesia
Tumor Necrosis Factor (TNF)
针刺疗法
肺癌手术
针药复合麻醉
Acupuncture Therapy
干扰素Ⅱ型
肿瘤坏死因子
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Notes Lung interferon
Combined Acupuncture and Drug Anesthesia
Tumor Necrosis Factor (YNF)
31-1908/R
R246.9
Cancer; γ-Acupuncture Therapy; Combined Acupuncture and Drug Anesthesia; Lung interferon Ⅱ; Tumor Necrosis Factor (YNF)
γ-Acupuncture Therapy
Cancer
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上海市肺科医院
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References Zhang La-di (BF02870130_CR4) 2002; 22
Cao Ming-fu (BF02870130_CR3) 2002; 35
Zhu Xiang-ping (BF02870130_CR2) 2002; 9
Ge-wei (BF02870130_CR5) 2002; 5
Jiang Zheng-hua (BF02870130_CR1) 1999; 22
References_xml – volume: 9
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  year: 2002
  ident: BF02870130_CR2
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– volume: 22
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– volume: 35
  start-page: 198
  issue: 3
  year: 2002
  ident: BF02870130_CR3
  publication-title: Journal of Experimental Biology
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Snippet Objective: To investigate the regulation of acupuncture on γ-interferon (INF-γ) and tumor necrosis factor (TNF) of lung cancer-operative cases.Methods: to...
R2; 目的:探讨肺癌手术患者应用针刺对γ-干扰素(INF-γ)和肿瘤坏死因子(TNF)的调节.方法:采用双抗体夹心免疫酶标法(ELISA)检测肺癌患者血清中INF-γ和肿瘤坏死因子含量;将针...
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SubjectTerms Acupuncture
General anesthesia
Lung cancer
Tumor necrosis factor-TNF
干扰素Ⅱ型
肺癌手术
肿瘤坏死因子
针刺疗法
针药复合麻醉
Title Regulation of Acupuncture on Interferon-γ and Tumor Necrosis Factor of Lung Cancer-Operative Cases
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