Les spondyloarthrites à début tardif

Les spondyloarthrites débutent principalement chez l’adulte jeune, cependant un début après 45 ou 50 ans n’est pas exceptionnel. La répartition du type de spondyloarthrite diffère chez le sujet âgé et notamment le rhumatisme psoriasique devient très prépondérant à cet âge. L’expression clinique des...

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Published inRevue du rhumatisme monographies Vol. 86; no. 3; pp. 190 - 194
Main Authors Dubost, Jean-Jacques, Tournadre, Anne, Soubrier, Martin
Format Journal Article
LanguageFrench
Published Elsevier Masson SAS 01.06.2019
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Online AccessGet full text
ISSN1878-6227
1878-6227
DOI10.1016/j.monrhu.2019.01.001

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Abstract Les spondyloarthrites débutent principalement chez l’adulte jeune, cependant un début après 45 ou 50 ans n’est pas exceptionnel. La répartition du type de spondyloarthrite diffère chez le sujet âgé et notamment le rhumatisme psoriasique devient très prépondérant à cet âge. L’expression clinique des spondyloarthrites à début tardif est aussi variée que chez le sujet jeune. La difficulté diagnostique tient au plus grand nombre de diagnostics différentiels et à la difficulté d’interpréter l’imagerie des sacro-iliaques et du rachis à cet âge. Certaines présentations trompeuses sont particulières au début tardif comme le LOPS (late onset peripheral spondyloarthritis) qui se caractérise par une oligoarthrite peu inflammatoire contrastant avec des signes généraux, un important syndrome inflammatoire et parfois des œdèmes asymétriques des membres inférieurs. Le tableau peut aussi évoquer une pseudo polyarthrite rhizomélique mais la cortico résistance doit attirer l’attention. L’âge avancé n’est pas, en soi, un argument suffisant pour récuser le diagnostic de spondyloarthrite. La présence d’antécédents familiaux de spondyloarthrite et du phénotype HLA B27 constitue souvent des arguments essentiels pour le diagnostic. Spondyloarthritis are usually observed in young adults, however an onset after 45 or even 50 years of age are not exceptional. The distribution of the type of spondyloarthritis differs in older subjects and in particular psoriatic arthritis becomes very preponderant at theses ages. The clinical expression of late-onset spondyloarthritis is as varied as in young patients. The diagnostic difficulty lies in the greater number of differential diagnoses and the difficulty of interpreting sacroiliac and spine imaging at this age. Some misleading presentations are common in late-onset disease, such as LOPS (late onset peripheral spondyloarthritis) consisting of mild inflammatory oligoarthritis that contrasts with general signs, severe inflammatory syndrome, and sometimes asymmetrical edema on the legs. Late-onset spondyloarthritis may presenting as polymyalgia rheumatica-like syndrome, but corticosteroid resistance should attract attention. Advanced age is not, in itself, a sufficient argument to reject a diagnosis of spondyloarthritis. A family history of spondyloarthritis and phenotype HLA B27 often constitute essential indicators pointing towards this diagnosis.
AbstractList Les spondyloarthrites débutent principalement chez l’adulte jeune, cependant un début après 45 ou 50 ans n’est pas exceptionnel. La répartition du type de spondyloarthrite diffère chez le sujet âgé et notamment le rhumatisme psoriasique devient très prépondérant à cet âge. L’expression clinique des spondyloarthrites à début tardif est aussi variée que chez le sujet jeune. La difficulté diagnostique tient au plus grand nombre de diagnostics différentiels et à la difficulté d’interpréter l’imagerie des sacro-iliaques et du rachis à cet âge. Certaines présentations trompeuses sont particulières au début tardif comme le LOPS (late onset peripheral spondyloarthritis) qui se caractérise par une oligoarthrite peu inflammatoire contrastant avec des signes généraux, un important syndrome inflammatoire et parfois des œdèmes asymétriques des membres inférieurs. Le tableau peut aussi évoquer une pseudo polyarthrite rhizomélique mais la cortico résistance doit attirer l’attention. L’âge avancé n’est pas, en soi, un argument suffisant pour récuser le diagnostic de spondyloarthrite. La présence d’antécédents familiaux de spondyloarthrite et du phénotype HLA B27 constitue souvent des arguments essentiels pour le diagnostic. Spondyloarthritis are usually observed in young adults, however an onset after 45 or even 50 years of age are not exceptional. The distribution of the type of spondyloarthritis differs in older subjects and in particular psoriatic arthritis becomes very preponderant at theses ages. The clinical expression of late-onset spondyloarthritis is as varied as in young patients. The diagnostic difficulty lies in the greater number of differential diagnoses and the difficulty of interpreting sacroiliac and spine imaging at this age. Some misleading presentations are common in late-onset disease, such as LOPS (late onset peripheral spondyloarthritis) consisting of mild inflammatory oligoarthritis that contrasts with general signs, severe inflammatory syndrome, and sometimes asymmetrical edema on the legs. Late-onset spondyloarthritis may presenting as polymyalgia rheumatica-like syndrome, but corticosteroid resistance should attract attention. Advanced age is not, in itself, a sufficient argument to reject a diagnosis of spondyloarthritis. A family history of spondyloarthritis and phenotype HLA B27 often constitute essential indicators pointing towards this diagnosis.
Author Soubrier, Martin
Dubost, Jean-Jacques
Tournadre, Anne
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Issue 3
Keywords Spondylarthrite ankylosante
Sujet âgé
Début tardif
Rhumatisme psoriasique
Spondyloarthritis
Late onset
Elderly
Spondyloarthrite
Ankylosing spondylitis
Psoriatic arthritis
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Snippet Les spondyloarthrites débutent principalement chez l’adulte jeune, cependant un début après 45 ou 50 ans n’est pas exceptionnel. La répartition du type de...
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StartPage 190
SubjectTerms Ankylosing spondylitis
Début tardif
Elderly
Late onset
Psoriatic arthritis
Rhumatisme psoriasique
Spondylarthrite ankylosante
Spondyloarthrite
Spondyloarthritis
Sujet âgé
Title Les spondyloarthrites à début tardif
URI https://dx.doi.org/10.1016/j.monrhu.2019.01.001
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