Lithium Toxicity at Therapeutic Blood Levels: A Case Report

This report describes a case of lithium toxicity occurring at therapeutic blood levels in a 47-year-old man with bipolar disorder and a history of alcohol abuse. We discuss the clinical presentation of lithium toxicity, as well as factors that may contribute to a reduction in the blood levels requir...

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Published inUniversity of Ottawa journal of medicine Vol. 5; no. 2; pp. 26 - 28
Main Authors Quimby, Alexandra Elizabeth, Sachdeva, Rajeev
Format Journal Article
LanguageEnglish
Published University of Ottawa 02.11.2015
Subjects
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ISSN2292-650X
2292-6518
DOI10.18192/uojm.v5i2.1368

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Abstract This report describes a case of lithium toxicity occurring at therapeutic blood levels in a 47-year-old man with bipolar disorder and a history of alcohol abuse. We discuss the clinical presentation of lithium toxicity, as well as factors that may contribute to a reduction in the blood levels required for the precipitation of toxic effects. In addition, we review the literature on cases of lithium toxicity occurring at therapeutic blood levels, including diagnosis and management thereof.RÉSUMÉ:Ce rapport décrit un cas de toxicité au lithium se produisant à des niveaux sanguins thérapeutiques chez un homme de 47 ans avec un trouble bipolaire et une histoire d’abus d’alcool. Nous discutons la présentation clinique de toxicité au lithium, ainsi que les facteurs pouvant contribuer à une réduction des niveaux sanguins nécessaires à la précipitation des effets toxiques. En outre, nous passons en revue la littérature sur les cas de toxicité au lithium se produisant à des niveaux sanguins thérapeutiques, y compris son diagnostic et sa gestion.
AbstractList This report describes a case of lithium toxicity occurring at therapeutic blood levels in a 47-year-old man with bipolar disorder and a history of alcohol abuse. We discuss the clinical presentation of lithium toxicity, as well as factors that may contribute to a reduction in the blood levels required for the precipitation of toxic effects. In addition, we review the literature on cases of lithium toxicity occurring at therapeutic blood levels, including diagnosis and management thereof. RÉSUMÉ: Ce rapport décrit un cas de toxicité au lithium se produisant à des niveaux sanguins thérapeutiques chez un homme de 47 ans avec un trouble bipolaire et une histoire d’abus d’alcool. Nous discutons la présentation clinique de toxicité au lithium, ainsi que les facteurs pouvant contribuer à une réduction des niveaux sanguins nécessaires à la précipitation des effets toxiques. En outre, nous passons en revue la littérature sur les cas de toxicité au lithium se produisant à des niveaux sanguins thérapeutiques, y compris son diagnostic et sa gestion.
Author Sachdeva, Rajeev
Quimby, Alexandra Elizabeth
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