22 Q11.2 DELETION SYDROME AND ALTERATION IN ORAL CAVITY: CLINICAL CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 129; no. 1; p. e70
• Main Authors: DE SOUSA BENTES, ALEXANDRA GABRIELLY, BARBOSA, JOYCE HELENA MONTEIRO, DA VERA CRUZ, CRISLYNE MENDES, BARROS, ANTONIA PATRICIA OLIVEIRA, DE SOUZA LOUZARDO, LEONARDO, DA VERA CRUZ, LUIZA MADALENA MENDES, PEDREIRA, ERICK NELO
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.01.2020
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2019.06.273

The 22 q11.2 deletion syndrome, also known as DiGeorge syndrome, is the subject of the loss of a submicroscopic segment of DNA in the 22 q11.2 region. It presents a great variability of clinical characteristics in affected individuals. Among the clinical manifestations are fissure of the palate, nasal speech, cardiovascular problems, and dysmorphic facial features. This case report describes a 15-year-old girl, clinically diagnosed as having DiGeorge syndrome, who attended a dental service for patients with special needs presenting with malocclusion, difficulty in chewing, and suspected heart disease. The patient was diagnosed with mixed developmental disorder and epilepsy, both uncontrolled, presenting pictures of hallucinations in the dental chair. The treatment plan was established through panoramic radiography, complete blood count, and medical release. Restorations, prophylaxis, scaling with fluorine application, and exodontia of elements 74, 83, and 84 were realized. The patient is still being treated at the dental health service.