Pulmonary Arterial Hypertension is Normalized Following Six Years of Inhaled Iloprost Treatment in a Patient with Systemic Sclerosis
Pulmonary arterial hypertension is a critical manifestation of systemic sclerosis (SSc) and is a main cause of death. Several treatment modalities for SSc have been identified, with effects that improve quality of life and mortality rates. However, whether these drugs can also normalize pulmonary ar...
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Published in | Journal of rheumatic diseases Vol. 24; no. 2; pp. 114 - 118 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
대한류마티스학회
01.04.2017
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Subjects | |
Online Access | Get full text |
ISSN | 2093-940X 2233-4718 2233-4718 |
DOI | 10.4078/jrd.2017.24.2.114 |
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Abstract | Pulmonary arterial hypertension is a critical manifestation of systemic sclerosis (SSc) and is a main cause of death. Several treatment modalities for SSc have been identified, with effects that improve quality of life and mortality rates. However, whether these drugs can also normalize pulmonary arterial pressure, remains unclear. Here, we report the case of a woman with diffuse SSc with pulmonary arterial hypertension, who had a functional status equivalent to the New York Heart Association class III.
The patient was treated with inhaled iloprost. After six years of inhaled iloprost therapy, echocardiography showed that pulmonary arterial pressure normalized, accompanied by improvement in functional capacity. Inhaled iloprost might not only normalize pulmonary arterial pressure, but also improve the functional status of patients with SSc with pulmonary arterial hypertension. (J Rheum Dis 2017;24:114-118) KCI Citation Count: 0 |
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AbstractList | Pulmonary arterial hypertension is a critical manifestation of systemic sclerosis (SSc) and is a main cause of death. Several treatment modalities for SSc have been identified, with effects that improve quality of life and mortality rates. However, whether these drugs can also normalize pulmonary arterial pressure, remains unclear. Here, we report the case of a woman with diffuse SSc with pulmonary arterial hypertension, who had a functional status equivalent to the New York Heart Association class III.
The patient was treated with inhaled iloprost. After six years of inhaled iloprost therapy, echocardiography showed that pulmonary arterial pressure normalized, accompanied by improvement in functional capacity. Inhaled iloprost might not only normalize pulmonary arterial pressure, but also improve the functional status of patients with SSc with pulmonary arterial hypertension. (J Rheum Dis 2017;24:114-118) KCI Citation Count: 0 |
Author | Kim, Hyoun-Ah Jung, Ju-Yang Yoo, Eun-Soo Yoon, So-Young Suh, Chang-Hee Yoo, Eun-Jung |
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Cites_doi | 10.1056/NEJMoa020204 10.1093/rheumatology/36.2.239 10.1253/circj.CJ-11-0473 10.1378/chest.10-0260 10.2147/VHRM.S3223 10.1093/rheumatology/keu450 10.1097/BOR.0b013e3283307dc8 10.1002/acr.22307 10.1056/NEJMoa012212 10.7326/0003-4819-132-6-200003210-00002 10.1002/art.30541 |
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References | Humbert (10.4078/jrd.2017.24.2.114_ref7) 2011; 63 Krug (10.4078/jrd.2017.24.2.114_ref11) 2009; 5 Miyamichi-Yamamoto (10.4078/jrd.2017.24.2.114_ref5) 2011; 75 Olschewski (10.4078/jrd.2017.24.2.114_ref3) 2002; 347 Denton (10.4078/jrd.2017.24.2.114_ref4) 1997; 36 Chung (10.4078/jrd.2017.24.2.114_ref6) 2010; 138 Badesch (10.4078/jrd.2017.24.2.114_ref10) 2000; 132 Rubin (10.4078/jrd.2017.24.2.114_ref9) 2002; 346 Pope (10.4078/jrd.2017.24.2.114_ref1) 2005; 32 Mathai (10.4078/jrd.2017.24.2.114_ref2) 2009; 21 Gopal (10.4078/jrd.2017.24.2.114_ref8) 2014; 66 Hachulla (10.4078/jrd.2017.24.2.114_ref12) 2015; 54 |
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Title | Pulmonary Arterial Hypertension is Normalized Following Six Years of Inhaled Iloprost Treatment in a Patient with Systemic Sclerosis |
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