Clinical Study on Skin of Layered Emulsion Containing Scutellaria baicalensis Root Extract

• Published in: Asian Journal of Beauty and Cosmetology Vol. 22; no. 4; pp. 681 - 689
• Main Authors: Choy, Yoon-Jung, Kim, Gyu-Ri
• Format: Journal Article
• Language: English
• Published: 한국피부과학연구원 01.12.2024
• Subjects: 미용
• ISSN: 2466-2046; 2466-2054
• DOI: 10.20402/ajbc.2024.0073

Purpose: The skin, particularly the stratum corneum, plays a crucial role in protection and moisture retention. Scutellaria baicalensis, well-known for its anti-inflammatory and antimicrobial properties, was studied for its potential to alleviate itch associated with atopic skin.Methods: A lamellar structured emulsion containing Scutellaria baicalensis root extract was prepared and tested on 21 adults. Participants applied the emulsion twice daily for 4 weeks. Skin surface moisture, tran-sepidermal water loss (TEWL), and itch severity were measured at baseline, after 2 weeks, and after 4 weeks using Corneometer CM825, Tewameter® TM 300, and visual analog scale (VAS), respec-tively. Adverse reactions were monitored. Statistical analysis was performed using SPSS Statistics 26.Results: Itch severity decreased significantly (6.86 to 2.81, p<0.001). No adverse reactions were reported.Conclusions: The emulsion significantly improved skin hydration, reduced TEWL, and alleviated itch, indicating its potential for enhancing skin barrier function and addressing dermatological concerns.