Epidemiology of atrial fibrillation in northeast China: a cross-sectional study, 2017–2019
ObjectiveTo evaluate the epidemiology of atrial fibrillation (AF) in northeast China.MethodsThis cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% ur...
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Published in | Heart (British Cardiac Society) Vol. 106; no. 8; pp. 590 - 595 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
BMJ Publishing Group Ltd and British Cardiovascular Society
01.04.2020
BMJ Publishing Group LTD |
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Online Access | Get full text |
ISSN | 1355-6037 1468-201X 1468-201X |
DOI | 10.1136/heartjnl-2019-315397 |
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Abstract | ObjectiveTo evaluate the epidemiology of atrial fibrillation (AF) in northeast China.MethodsThis cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All participants completed a questionnaire and underwent a physical examination and ECG. AF was diagnosed according to history and ECG findings.ResultsThe overall AF prevalence was 1.1%; it increased steeply with age. AF was more prevalent in men than in women (1.5% vs 0.9%, p<0.001); however, the difference between urban and rural areas was not significant (1.3% vs 1.1%, p=0.228). Among the AF population, the overall AF awareness rate was 52.6%, higher in women than in men (61.5% vs 44.1%, p=0.011); however, the difference between areas was not statistically significant (60.0% vs 49.0%, p=0.129). According to the CHA2DS-VASc score, almost all (90.2%, 194/215) of our subjects required oral anticoagulant (OAC) therapy; however, only 4.1% actually received it. Moreover, hypertension (66.5%), dyslipidaemia (32.6%) and diabetes (24.2%) were highly prevalent in patients with AF, but their control rates were unacceptably low (7.0%, 8.6% and 28.8%, respectively).ConclusionsThe burden of AF in northeast China was substantial. Underuse of OAC therapy and uncontrolled comorbidities will likely contribute to the cardiovascular outcomes of patients with AF in the coming decades. Long-term management strategies for AF and related risk factors are required in northeast China. |
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AbstractList | To evaluate the epidemiology of atrial fibrillation (AF) in northeast China.
This cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All participants completed a questionnaire and underwent a physical examination and ECG. AF was diagnosed according to history and ECG findings.
The overall AF prevalence was 1.1%; it increased steeply with age. AF was more prevalent in men than in women (1.5% vs 0.9%, p<0.001); however, the difference between urban and rural areas was not significant (1.3% vs 1.1%, p=0.228). Among the AF population, the overall AF awareness rate was 52.6%, higher in women than in men (61.5% vs 44.1%, p=0.011); however, the difference between areas was not statistically significant (60.0% vs 49.0%, p=0.129). According to the CHA
DS-VASc score, almost all (90.2%, 194/215) of our subjects required oral anticoagulant (OAC) therapy; however, only 4.1% actually received it. Moreover, hypertension (66.5%), dyslipidaemia (32.6%) and diabetes (24.2%) were highly prevalent in patients with AF, but their control rates were unacceptably low (7.0%, 8.6% and 28.8%, respectively).
The burden of AF in northeast China was substantial. Underuse of OAC therapy and uncontrolled comorbidities will likely contribute to the cardiovascular outcomes of patients with AF in the coming decades. Long-term management strategies for AF and related risk factors are required in northeast China. To evaluate the epidemiology of atrial fibrillation (AF) in northeast China.OBJECTIVETo evaluate the epidemiology of atrial fibrillation (AF) in northeast China.This cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All participants completed a questionnaire and underwent a physical examination and ECG. AF was diagnosed according to history and ECG findings.METHODSThis cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All participants completed a questionnaire and underwent a physical examination and ECG. AF was diagnosed according to history and ECG findings.The overall AF prevalence was 1.1%; it increased steeply with age. AF was more prevalent in men than in women (1.5% vs 0.9%, p<0.001); however, the difference between urban and rural areas was not significant (1.3% vs 1.1%, p=0.228). Among the AF population, the overall AF awareness rate was 52.6%, higher in women than in men (61.5% vs 44.1%, p=0.011); however, the difference between areas was not statistically significant (60.0% vs 49.0%, p=0.129). According to the CHA2DS-VASc score, almost all (90.2%, 194/215) of our subjects required oral anticoagulant (OAC) therapy; however, only 4.1% actually received it. Moreover, hypertension (66.5%), dyslipidaemia (32.6%) and diabetes (24.2%) were highly prevalent in patients with AF, but their control rates were unacceptably low (7.0%, 8.6% and 28.8%, respectively).RESULTSThe overall AF prevalence was 1.1%; it increased steeply with age. AF was more prevalent in men than in women (1.5% vs 0.9%, p<0.001); however, the difference between urban and rural areas was not significant (1.3% vs 1.1%, p=0.228). Among the AF population, the overall AF awareness rate was 52.6%, higher in women than in men (61.5% vs 44.1%, p=0.011); however, the difference between areas was not statistically significant (60.0% vs 49.0%, p=0.129). According to the CHA2DS-VASc score, almost all (90.2%, 194/215) of our subjects required oral anticoagulant (OAC) therapy; however, only 4.1% actually received it. Moreover, hypertension (66.5%), dyslipidaemia (32.6%) and diabetes (24.2%) were highly prevalent in patients with AF, but their control rates were unacceptably low (7.0%, 8.6% and 28.8%, respectively).The burden of AF in northeast China was substantial. Underuse of OAC therapy and uncontrolled comorbidities will likely contribute to the cardiovascular outcomes of patients with AF in the coming decades. Long-term management strategies for AF and related risk factors are required in northeast China.CONCLUSIONSThe burden of AF in northeast China was substantial. Underuse of OAC therapy and uncontrolled comorbidities will likely contribute to the cardiovascular outcomes of patients with AF in the coming decades. Long-term management strategies for AF and related risk factors are required in northeast China. ObjectiveTo evaluate the epidemiology of atrial fibrillation (AF) in northeast China.MethodsThis cross-sectional survey using a multistage, stratified and cluster random sampling method was conducted in Liaoning Province between September 2017 and March 2019. A total of 18 796 participants (28.9% urban, 71.1% rural) aged ≥40 years were included. All participants completed a questionnaire and underwent a physical examination and ECG. AF was diagnosed according to history and ECG findings.ResultsThe overall AF prevalence was 1.1%; it increased steeply with age. AF was more prevalent in men than in women (1.5% vs 0.9%, p<0.001); however, the difference between urban and rural areas was not significant (1.3% vs 1.1%, p=0.228). Among the AF population, the overall AF awareness rate was 52.6%, higher in women than in men (61.5% vs 44.1%, p=0.011); however, the difference between areas was not statistically significant (60.0% vs 49.0%, p=0.129). According to the CHA2DS-VASc score, almost all (90.2%, 194/215) of our subjects required oral anticoagulant (OAC) therapy; however, only 4.1% actually received it. Moreover, hypertension (66.5%), dyslipidaemia (32.6%) and diabetes (24.2%) were highly prevalent in patients with AF, but their control rates were unacceptably low (7.0%, 8.6% and 28.8%, respectively).ConclusionsThe burden of AF in northeast China was substantial. Underuse of OAC therapy and uncontrolled comorbidities will likely contribute to the cardiovascular outcomes of patients with AF in the coming decades. Long-term management strategies for AF and related risk factors are required in northeast China. |
Author | Sun, Qun Chen, Hongyun Dai, Dong Xing, Liying Yan, Han Dong, Yingna Jing, Li Lin, Min Shi, Lei Du, Zhi Ren, Guocheng Tian, Yuanmeng Liu, Shuang |
Author_xml | – sequence: 1 givenname: Liying surname: Xing fullname: Xing, Liying organization: Department of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, People’s Republic of China – sequence: 2 givenname: Min surname: Lin fullname: Lin, Min organization: Department of Cardiology, Central Hospital of Ben Xi City, Ben Xi, Liaoning, Benxi, China – sequence: 3 givenname: Zhi surname: Du fullname: Du, Zhi organization: Department of Cardiology, The First Hospital of China Medical University, Shenyang, People’s Republic of China – sequence: 4 givenname: Li surname: Jing fullname: Jing, Li organization: Department of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, People’s Republic of China – sequence: 5 givenname: Yuanmeng surname: Tian fullname: Tian, Yuanmeng organization: Department of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, People’s Republic of China – sequence: 6 givenname: Han surname: Yan fullname: Yan, Han organization: Department of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, People’s Republic of China – sequence: 7 givenname: Guocheng surname: Ren fullname: Ren, Guocheng organization: Department of Disease Control and Preventive, Central Hospital of Chao Yang City, Chaoyang, People’s Republic of China – sequence: 8 givenname: Yingna surname: Dong fullname: Dong, Yingna organization: Department of Disease Control and Preventive, Central Hospital of Chao Yang City, Chaoyang, People’s Republic of China – sequence: 9 givenname: Qun surname: Sun fullname: Sun, Qun organization: Department of Chronic Disease, Disease Control and Prevention of Chao Yang City, Chaoyang, People’s Republic of China – sequence: 10 givenname: Dong surname: Dai fullname: Dai, Dong organization: Department of Chronic Disease, Disease Control and Prevention of Dan Dong City, Dan Dong, People’s Republic of China – sequence: 11 givenname: Lei surname: Shi fullname: Shi, Lei organization: Department of Chronic Disease, Disease Control and Prevention of Liao Yang City, Liaoyang, People’s Republic of China – sequence: 12 givenname: Hongyun surname: Chen fullname: Chen, Hongyun organization: Department of Cardiology, Central Hospital of Da Lian City, Dalian, People’s Republic of China – sequence: 13 givenname: Shuang orcidid: 0000-0002-4799-0481 surname: Liu fullname: Liu, Shuang email: cmu1h@163.com organization: Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, China |
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Keywords | cardiac risk factors and prevention epidemiology atrial fibrillation |
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publication-title: Sci Rep doi: 10.1038/s41598-018-35928-w – volume: 285 start-page: 2370 year: 2001 ident: key-10.1136/heartjnl-2019-315397-23 article-title: Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (atria) study publication-title: JAMA doi: 10.1001/jama.285.18.2370 – volume: 32 start-page: 777 year: 2019 ident: key-10.1136/heartjnl-2019-315397-10 article-title: Cross-sectional association between blood pressure status and atrial fibrillation in an elderly Chinese population publication-title: Am J Hypertens doi: 10.1093/ajh/hpz060 – volume: 164 start-page: 542 year: 2016 ident: key-10.1136/heartjnl-2019-315397-17 article-title: Diagnosis and management of diabetes: synopsis of the 2016 American Diabetes Association Standards of Medical Care in Diabetes publication-title: Ann Intern Med doi: 10.7326/M15-3016 – volume: 271 start-page: 840 year: 1994 ident: key-10.1136/heartjnl-2019-315397-27 article-title: Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham heart study publication-title: JAMA doi: 10.1001/jama.1994.03510350050036 – volume: 182 start-page: 13 year: 2015 ident: key-10.1136/heartjnl-2019-315397-8 article-title: Prevalence of atrial fibrillation and its risk factors in rural China: a cross-sectional study publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2014.12.063 – volume: 28 start-page: 81 year: 2018 ident: key-10.1136/heartjnl-2019-315397-26 article-title: Trend of prevalence of atrial fibrillation and use of oral anticoagulation therapy in patients with atrial fibrillation in South Korea (2002-2013) publication-title: J Epidemiol doi: 10.2188/jea.JE20160149 – volume: 37 start-page: 2893 year: 2016 ident: key-10.1136/heartjnl-2019-315397-15 article-title: 2016 ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS publication-title: Eur Heart J doi: 10.1093/eurheartj/ehw210 – year: 2019 ident: key-10.1136/heartjnl-2019-315397-18 article-title: High prevalence of stroke and uncontrolled associated risk factors are major public health challenges in rural northeast China: a population-based study publication-title: Int J Stroke – volume: 14 start-page: 1385 year: 2012 ident: key-10.1136/heartjnl-2019-315397-22 article-title: 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation--developed with the special contribution of the European Heart Rhythm Association publication-title: Europace doi: 10.1093/europace/eus305 |
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Snippet | ObjectiveTo evaluate the epidemiology of atrial fibrillation (AF) in northeast China.MethodsThis cross-sectional survey using a multistage, stratified and... To evaluate the epidemiology of atrial fibrillation (AF) in northeast China. This cross-sectional survey using a multistage, stratified and cluster random... To evaluate the epidemiology of atrial fibrillation (AF) in northeast China.OBJECTIVETo evaluate the epidemiology of atrial fibrillation (AF) in northeast... |
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SubjectTerms | Adult Aged Aged, 80 and over Anticoagulants atrial fibrillation Atrial Fibrillation - epidemiology Cardiac arrhythmia Cardiac risk factors and prevention Cardiology China - epidemiology Cholesterol Cross-Sectional Studies Data collection Epidemiology Female Humans Hypertension Laboratories Lipids Male Medical prognosis Middle Aged Patients Population Prevalence Questionnaires Retrospective Studies Risk Factors Rural Population Studies |
Title | Epidemiology of atrial fibrillation in northeast China: a cross-sectional study, 2017–2019 |
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