Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials

ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DesignSystematic review and meta-analysis.Data sourcesMedline, EMBASE and COCHRANE from 1990 to June 2018.Eligibility criteriaRandomi...

Full description

Saved in:
Bibliographic Details
Published inBMJ open Vol. 9; no. 3; p. e017995
Main Authors Koutnikova, Hana, Genser, Bernd, Monteiro-Sepulveda, Milena, Faurie, Jean-Michel, Rizkalla, Salwa, Schrezenmeir, Jürgen, Clément, Karine
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group LTD 30.03.2019
BMJ Publishing Group
Subjects
Clinical trials
Diabetes
Diabetes Mellitus - metabolism
Diabetes Mellitus - therapy
Dietary Supplements
Endocrinology and metabolism
Evidence-based medicine
Fatty liver
Food and Nutrition
Human health and pathology
Humans
Insulin resistance
Life Sciences
Liver diseases
Meta-analysis
Non-alcoholic Fatty Liver Disease - metabolism
Non-alcoholic Fatty Liver Disease - therapy
Nutrition and Metabolism
Obesity
Obesity - metabolism
Obesity - therapy
Probiotics
Probiotics - pharmacology
Randomized Controlled Trials as Topic
Santé publique et épidémiologie
Systematic review
Treatment Outcome
lactobacillus
non-alcoholic fatty liver disease
diabetes
bifidobacterium
obesity
probiotics
Online AccessGet full text
ISSN2044-6055
2044-6055
DOI10.1136/bmjopen-2017-017995

Cover

Abstract ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DesignSystematic review and meta-analysis.Data sourcesMedline, EMBASE and COCHRANE from 1990 to June 2018.Eligibility criteriaRandomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years.ResultsOne hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=−0.94 kg mean difference, 95% CI −1.17 to −0.70, I²=0.0%), body mass index (k=32, d=−0.55 kg/m², 95% CI −0.86 to −0.23, I²=91.9%), waist circumference (k=13, d=−1.31 cm, 95% CI −1.79 to −0.83, I²=14.5%), body fat mass (k=11, d=−0.96 kg, 95% CI −1.21 to −0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=−6.30 cm², 95% CI −9.05 to −3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=−0.66 mmol/L, 95% CI −1.00 to −0.31, I²=27.7%), glycated haemoglobin (k=13, d=−0.28 pp, 95% CI −0.46 to −0.11, I²=54.1%), insulin (k=13, d=−1.66 mU/L, 95% CI −2.70 to −0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=−1.05 pp, 95% CI −1.48 to −0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=−10.2 U/L, 95% CI −14.3 to −6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=−9.9 U/L, 95% CI −14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria (Bifidobacterium breve, B. longum), Streptococcus salivarius subsp. thermophilus and lactobacilli (Lactobacillus acidophilus, L. casei, L. delbrueckii) containing mixtures and influenced by trials conducted in one country.ConclusionsThe intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases.Trial registration numberCRD42016033273.
AbstractList To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.OBJECTIVETo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.Systematic review and meta-analysis.DESIGNSystematic review and meta-analysis.Medline, EMBASE and COCHRANE from 1990 to June 2018.DATA SOURCESMedline, EMBASE and COCHRANE from 1990 to June 2018.Randomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years.ELIGIBILITY CRITERIARandomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years.One hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=-0.94 kg mean difference, 95% CI -1.17 to -0.70, I²=0.0%), body mass index (k=32, d=-0.55 kg/m², 95% CI -0.86 to -0.23, I²=91.9%), waist circumference (k=13, d=-1.31 cm, 95% CI -1.79 to -0.83, I²=14.5%), body fat mass (k=11, d=-0.96 kg, 95% CI -1.21 to -0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=-6.30 cm², 95% CI -9.05 to -3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=-0.66 mmol/L, 95% CI -1.00 to -0.31, I²=27.7%), glycated haemoglobin (k=13, d=-0.28 pp, 95% CI -0.46 to -0.11, I²=54.1%), insulin (k=13, d=-1.66 mU/L, 95% CI -2.70 to -0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=-1.05 pp, 95% CI -1.48 to -0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=-10.2 U/L, 95% CI -14.3 to -6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=-9.9 U/L, 95% CI -14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria (Bifidobacterium breve, B. longum), Streptococcus salivarius subsp. thermophilus and lactobacilli (Lactobacillus acidophilus, L. casei, L. delbrueckii) containing mixtures and influenced by trials conducted in one country.RESULTSOne hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=-0.94 kg mean difference, 95% CI -1.17 to -0.70, I²=0.0%), body mass index (k=32, d=-0.55 kg/m², 95% CI -0.86 to -0.23, I²=91.9%), waist circumference (k=13, d=-1.31 cm, 95% CI -1.79 to -0.83, I²=14.5%), body fat mass (k=11, d=-0.96 kg, 95% CI -1.21 to -0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=-6.30 cm², 95% CI -9.05 to -3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=-0.66 mmol/L, 95% CI -1.00 to -0.31, I²=27.7%), glycated haemoglobin (k=13, d=-0.28 pp, 95% CI -0.46 to -0.11, I²=54.1%), insulin (k=13, d=-1.66 mU/L, 95% CI -2.70 to -0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=-1.05 pp, 95% CI -1.48 to -0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=-10.2 U/L, 95% CI -14.3 to -6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=-9.9 U/L, 95% CI -14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria (Bifidobacterium breve, B. longum), Streptococcus salivarius subsp. thermophilus and lactobacilli (Lactobacillus acidophilus, L. casei, L. delbrueckii) containing mixtures and influenced by trials conducted in one country.The intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases.CONCLUSIONSThe intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases.CRD42016033273.TRIAL REGISTRATION NUMBERCRD42016033273.
To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease. Systematic review and meta-analysis. Medline, EMBASE and COCHRANE from 1990 to June 2018. Randomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years. One hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=-0.94 kg mean difference, 95% CI -1.17 to -0.70, I²=0.0%), body mass index (k=32, d=-0.55 kg/m², 95% CI -0.86 to -0.23, I²=91.9%), waist circumference (k=13, d=-1.31 cm, 95% CI -1.79 to -0.83, I²=14.5%), body fat mass (k=11, d=-0.96 kg, 95% CI -1.21 to -0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=-6.30 cm², 95% CI -9.05 to -3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=-0.66 mmol/L, 95% CI -1.00 to -0.31, I²=27.7%), glycated haemoglobin (k=13, d=-0.28 pp, 95% CI -0.46 to -0.11, I²=54.1%), insulin (k=13, d=-1.66 mU/L, 95% CI -2.70 to -0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=-1.05 pp, 95% CI -1.48 to -0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=-10.2 U/L, 95% CI -14.3 to -6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=-9.9 U/L, 95% CI -14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria ( , ), subsp and lactobacilli ( , , ) containing mixtures and influenced by trials conducted in one country. The intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases. CRD42016033273.
ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DesignSystematic review and meta-analysis.Data sourcesMedline, EMBASE and COCHRANE from 1990 to June 2018.Eligibility criteriaRandomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years.ResultsOne hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=−0.94 kg mean difference, 95% CI −1.17 to −0.70, I²=0.0%), body mass index (k=32, d=−0.55 kg/m², 95% CI −0.86 to −0.23, I²=91.9%), waist circumference (k=13, d=−1.31 cm, 95% CI −1.79 to −0.83, I²=14.5%), body fat mass (k=11, d=−0.96 kg, 95% CI −1.21 to −0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=−6.30 cm², 95% CI −9.05 to −3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=−0.66 mmol/L, 95% CI −1.00 to −0.31, I²=27.7%), glycated haemoglobin (k=13, d=−0.28 pp, 95% CI −0.46 to −0.11, I²=54.1%), insulin (k=13, d=−1.66 mU/L, 95% CI −2.70 to −0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=−1.05 pp, 95% CI −1.48 to −0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=−10.2 U/L, 95% CI −14.3 to −6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=−9.9 U/L, 95% CI −14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria (Bifidobacterium breve, B. longum), Streptococcus salivarius subsp. thermophilus and lactobacilli (Lactobacillus acidophilus, L. casei, L. delbrueckii) containing mixtures and influenced by trials conducted in one country.ConclusionsThe intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases.Trial registration numberCRD42016033273.
OBJECTIVE: To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DESIGN: Systematic review and meta-analysis.DATA SOURCES: Medline, EMBASE and COCHRANE from 1990 to June 2018.ELIGIBILITY CRITERIA: Randomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children <3 years.RESULTS: One hundred and five articles met inclusion criteria, representing 6826 subjects. In overweight but not obese subjects, probiotics induced improvements in: body weight (k=25 trials, d=-0.94 kg mean difference, 95% CI -1.17 to -0.70, I²=0.0%), body mass index (k=32, d=-0.55 kg/m², 95% CI -0.86 to -0.23, I²=91.9%), waist circumference (k=13, d=-1.31 cm, 95% CI -1.79 to -0.83, I²=14.5%), body fat mass (k=11, d=-0.96 kg, 95% CI -1.21 to -0.71, I²=0.0%) and visceral adipose tissue mass (k=5, d=-6.30 cm², 95% CI -9.05 to -3.56, I²=0.0%). In type 2 diabetics, probiotics reduced fasting glucose (k=19, d=-0.66 mmol/L, 95% CI -1.00 to -0.31, I²=27.7%), glycated haemoglobin (k=13, d=-0.28 pp, 95% CI -0.46 to -0.11, I²=54.1%), insulin (k=13, d=-1.66 mU/L, 95% CI -2.70 to -0.61, I²=37.8%) and homeostatic model of insulin resistance (k=10, d=-1.05 pp, 95% CI -1.48 to -0.61, I²=18.2%). In subjects with fatty liver diseases, probiotics reduced alanine (k=12, d=-10.2 U/L, 95% CI -14.3 to -6.0, I²=93.50%) and aspartate aminotransferases (k=10, d=-9.9 U/L, 95% CI -14.1 to -5.8, I²=96.1%). These improvements were mostly observed with bifidobacteria (Bifidobacterium breve, B. longum), Streptococcus salivarius subsp. thermophilus and lactobacilli (Lactobacillus acidophilus, L. casei, L. delbrueckii) containing mixtures and influenced by trials conducted in one country.CONCLUSIONS: The intake of probiotics resulted in minor but consistent improvements in several metabolic risk factors in subjects with metabolic diseases.
Author Koutnikova, Hana
Schrezenmeir, Jürgen
Faurie, Jean-Michel
Genser, Bernd
Clément, Karine
Monteiro-Sepulveda, Milena
Rizkalla, Salwa
AuthorAffiliation 6 Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), NutriOmiCs team , UMR S 1269 , Paris , France
4 Nutrition Department , Pitie-Salpêtrière hospital, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris , Paris , France
5 Clinical Research Center Kiel , Johannes Gutenberg Universitat Universitatsmedizin , Mainz , Rheinland-Pfalz , Germany
1 Danone Nutricia Research , Palaiseau , France
2 BGStats Consulting , Vienna , Austria
3 Mannheimer Institut fur Public Health , Ruprecht Karls Universitat Heidelberg , Mannheim , Baden-Württemberg , Germany
AuthorAffiliation_xml – name: 1 Danone Nutricia Research , Palaiseau , France
– name: 6 Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), NutriOmiCs team , UMR S 1269 , Paris , France
– name: 3 Mannheimer Institut fur Public Health , Ruprecht Karls Universitat Heidelberg , Mannheim , Baden-Württemberg , Germany
– name: 2 BGStats Consulting , Vienna , Austria
– name: 4 Nutrition Department , Pitie-Salpêtrière hospital, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris , Paris , France
– name: 5 Clinical Research Center Kiel , Johannes Gutenberg Universitat Universitatsmedizin , Mainz , Rheinland-Pfalz , Germany
Author_xml – sequence: 1
  givenname: Hana
  surname: Koutnikova
  fullname: Koutnikova, Hana
  email: karine.clement@psl.aphp.fr
  organization: Danone Nutricia Research, Palaiseau, France
– sequence: 2
  givenname: Bernd
  surname: Genser
  fullname: Genser, Bernd
  email: karine.clement@psl.aphp.fr
  organization: Mannheimer Institut fur Public Health, Ruprecht Karls Universitat Heidelberg, Mannheim, Baden-Württemberg, Germany
– sequence: 3
  givenname: Milena
  surname: Monteiro-Sepulveda
  fullname: Monteiro-Sepulveda, Milena
  email: karine.clement@psl.aphp.fr
  organization: Nutrition Department, Pitie-Salpêtrière hospital, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris, Paris, France
– sequence: 4
  givenname: Jean-Michel
  surname: Faurie
  fullname: Faurie, Jean-Michel
  email: karine.clement@psl.aphp.fr
  organization: Danone Nutricia Research, Palaiseau, France
– sequence: 5
  givenname: Salwa
  surname: Rizkalla
  fullname: Rizkalla, Salwa
  email: karine.clement@psl.aphp.fr
  organization: Nutrition Department, Pitie-Salpêtrière hospital, Institute of Cardiometabolism and Nutrition, Assistance Publique-Hôpitaux de Paris, Paris, France
– sequence: 6
  givenname: Jürgen
  surname: Schrezenmeir
  fullname: Schrezenmeir, Jürgen
  email: karine.clement@psl.aphp.fr
  organization: Clinical Research Center Kiel, Johannes Gutenberg Universitat Universitatsmedizin, Mainz, Rheinland-Pfalz, Germany
– sequence: 7
  givenname: Karine
  orcidid: 0000-0003-4619-6785
  surname: Clément
  fullname: Clément, Karine
  email: karine.clement@psl.aphp.fr
  organization: Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), NutriOmiCs team, UMR S , Paris, France
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30928918$$D View this record in MEDLINE/PubMed
https://hal.sorbonne-universite.fr/hal-02165922$$DView record in HAL
BookMark eNqNUl1rFDEUHaRia-0vECTgi4JTk8xkPvoglKK2sOCLPockc8fNkpmsSXZk_5a_0DudrdR9EAPJDbnnnJzk3ufZyehHyLKXjF4yVlTv9bDxWxhzTlmd42xb8SQ747Qs84oKcfJof5pdxLihOErRCsGfZacFbXnTsuYs-3U3bJVJxPdEY4RglSPb4LX1yZpI_Ei8hmjT_h3prNKQIBI1dgT95MoZv_bOGtKrlPbE2QkCwiKoCCSAUwk6MikU1Q7iFVEk7mOCQaE25icLP-_FBkgqV6Ny-2jj7CXgqR9QqCPGjyl453CbZnfxRfa0xwAXh3ieffv08evNbb768vnu5nqVa0GrhGttgNe9EQ3THe9FwRhTVV_XDdRQtrqBqqAN6zhr26oRlWbA6qKpEQ2s7Ivz7MOiu93pAToD6EM5uQ12UGEvvbLy78xo1_K7n2RV1oIXDAXeLgLrI9rt9UrOZ5SzSrScTzP2zeGy4H_sICaJrzfgnBrB76Lkc6EZ-hMIfX0E3fhdwM-7R1HGayw9ol49dv_n_ofSI6BdACb4GAP00tiEhZm_W1knGZVzp8lDp8nZgFw6DbnFEfdB_t-sy4WFyf8i_Aa7V-rw
CitedBy_id crossref_primary_10_1016_j_medmic_2019_100002
crossref_primary_10_3390_molecules27165111
crossref_primary_10_21518_ms2024_371
crossref_primary_10_1016_j_phrs_2022_106397
crossref_primary_10_3390_nu13030987
crossref_primary_10_3390_ijms22189700
crossref_primary_10_1155_2024_4183880
crossref_primary_10_3390_biology10050447
crossref_primary_10_3390_microorganisms8010035
crossref_primary_10_26599_FSHW_2022_9250071
crossref_primary_10_1016_j_tjnut_2024_08_014
crossref_primary_10_3389_fnut_2022_846873
crossref_primary_10_1172_JCI143770
crossref_primary_10_2147_NDS_S243097
crossref_primary_10_1016_j_hlc_2021_09_006
crossref_primary_10_1186_s12872_024_03804_3
crossref_primary_10_1210_endrev_bnz009
crossref_primary_10_1007_s40519_020_00983_8
crossref_primary_10_3389_fnut_2023_1261148
crossref_primary_10_1016_j_jff_2022_105203
crossref_primary_10_1186_s13073_022_01092_0
crossref_primary_10_33667_2078_5631_2020_30_48_53
crossref_primary_10_1007_s11892_019_1180_z
crossref_primary_10_1016_j_numecd_2022_04_007
crossref_primary_10_3892_etm_2021_10747
crossref_primary_10_1016_j_foodres_2022_112309
crossref_primary_10_1016_j_idairyj_2023_105700
crossref_primary_10_1007_s12602_024_10363_8
crossref_primary_10_1007_s11901_020_00547_5
crossref_primary_10_1016_j_clnesp_2024_11_011
crossref_primary_10_3389_fnut_2022_1024678
crossref_primary_10_1016_j_fshw_2022_10_023
crossref_primary_10_1590_0102_672020190001e1498
crossref_primary_10_1111_1751_7915_13769
crossref_primary_10_3389_fimmu_2021_578386
crossref_primary_10_3389_fnut_2020_593735
crossref_primary_10_3389_fcimb_2020_596166
crossref_primary_10_3389_fnut_2024_1475111
crossref_primary_10_1016_j_celrep_2021_109093
crossref_primary_10_2991_artres_k_200429_001
crossref_primary_10_1002_oby_22806
crossref_primary_10_54393_df_v3i1_45
crossref_primary_10_1016_j_tim_2021_01_003
crossref_primary_10_3390_microorganisms11040962
crossref_primary_10_1111_cns_14704
crossref_primary_10_1097_MS9_0000000000001740
crossref_primary_10_3390_nu13061902
crossref_primary_10_1007_s00253_022_12265_7
crossref_primary_10_1097_HEP_0000000000000598
crossref_primary_10_3390_jcm9061788
crossref_primary_10_1139_apnm_2021_0637
crossref_primary_10_1016_j_nutres_2025_03_002
crossref_primary_10_1097_MS9_0000000000002276
crossref_primary_10_3920_BM2020_0111
crossref_primary_10_7554_eLife_63998
crossref_primary_10_1007_s40200_024_01400_y
crossref_primary_10_1016_j_biopha_2023_114400
crossref_primary_10_3389_fmicb_2024_1358525
crossref_primary_10_1097_TP_0000000000003494
crossref_primary_10_1007_s40200_021_00765_8
crossref_primary_10_1111_all_14549
crossref_primary_10_3390_nu11112837
crossref_primary_10_1016_j_clnu_2020_10_028
crossref_primary_10_1007_s10311_019_00896_8
crossref_primary_10_1152_ajpgi_00227_2024
crossref_primary_10_17816_mechnikov104795
crossref_primary_10_1039_D4FO02561J
crossref_primary_10_1186_s40795_024_00976_1
crossref_primary_10_1038_s41598_023_48718_w
crossref_primary_10_1590_0102_672020200002e1520
crossref_primary_10_3390_nu15061323
crossref_primary_10_3390_ijms24076755
crossref_primary_10_3389_fendo_2024_1277921
crossref_primary_10_1038_s41598_024_52077_5
crossref_primary_10_1016_j_clnu_2022_07_003
crossref_primary_10_1186_s13033_020_00410_6
crossref_primary_10_3390_jpm12081282
crossref_primary_10_1016_j_dsx_2024_103110
crossref_primary_10_1186_s13098_024_01561_z
crossref_primary_10_1538_expanim_21_0182
crossref_primary_10_1038_s41598_020_78285_3
crossref_primary_10_1016_j_nupar_2019_12_001
crossref_primary_10_1080_19490976_2020_1840766
crossref_primary_10_1016_j_ejphar_2022_175069
crossref_primary_10_1186_s12866_021_02263_6
crossref_primary_10_1016_j_fbio_2021_101115
crossref_primary_10_1016_j_ijbiomac_2019_09_159
crossref_primary_10_4254_wjh_v13_i9_1154
crossref_primary_10_3389_fimmu_2022_974872
crossref_primary_10_1080_21655979_2023_2185941
crossref_primary_10_1093_nutrit_nuad086
crossref_primary_10_1007_s11695_020_04956_9
crossref_primary_10_1080_10408398_2022_2028716
crossref_primary_10_7759_cureus_40948
crossref_primary_10_1038_s41387_024_00281_7
crossref_primary_10_1016_j_clnesp_2023_07_087
crossref_primary_10_1053_j_gastro_2020_01_049
crossref_primary_10_1155_2021_6688450
crossref_primary_10_3168_jds_2019_17401
crossref_primary_10_3390_nu14214681
crossref_primary_10_1007_s13679_020_00379_w
crossref_primary_10_1080_1028415X_2020_1826763
crossref_primary_10_1007_s12088_024_01433_0
crossref_primary_10_3390_jcm10071342
crossref_primary_10_1016_j_phymed_2024_156151
crossref_primary_10_3390_microorganisms12020234
crossref_primary_10_1016_j_obmed_2023_100489
crossref_primary_10_1007_s11154_019_09512_0
crossref_primary_10_1155_2021_5542626
crossref_primary_10_3389_fnut_2024_1330903
crossref_primary_10_3390_cells12091260
crossref_primary_10_1186_s12902_023_01338_x
crossref_primary_10_3390_nu15133039
crossref_primary_10_1007_s12602_023_10198_9
crossref_primary_10_1155_2022_2123162
crossref_primary_10_3390_microorganisms12040642
crossref_primary_10_1080_19490976_2021_1907270
crossref_primary_10_1186_s12889_024_18494_x
crossref_primary_10_23736_S1121_421X_20_02671_9
crossref_primary_10_3389_fmicb_2024_1488656
crossref_primary_10_1016_j_scitotenv_2020_143836
crossref_primary_10_1590_2175_8239_jbn_2023_e005en
crossref_primary_10_3389_fnut_2022_844242
crossref_primary_10_1016_j_ajogmf_2023_101148
crossref_primary_10_1021_acs_jafc_2c04476
crossref_primary_10_1016_j_phanu_2021_100261
crossref_primary_10_1080_10408398_2022_2117783
crossref_primary_10_1080_19490976_2024_2309683
crossref_primary_10_1186_s12950_021_00272_w
crossref_primary_10_3390_coatings12060838
crossref_primary_10_3748_wjg_v27_i37_6161
crossref_primary_10_1007_s42832_023_0225_z
crossref_primary_10_3390_microorganisms8081148
crossref_primary_10_1016_j_phanu_2021_100266
crossref_primary_10_3390_ph14040384
crossref_primary_10_3920_BM2021_0171
crossref_primary_10_1097_MD_0000000000034978
crossref_primary_10_1080_19490976_2023_2181930
crossref_primary_10_1002_mnfr_202000375
crossref_primary_10_1016_j_jff_2021_104494
crossref_primary_10_48022_mbl_2210_10013
crossref_primary_10_1016_j_lfs_2024_122948
crossref_primary_10_1111_obr_13409
crossref_primary_10_1590_2175_8239_jbn_2023_e005pt
crossref_primary_10_1089_jmf_2020_4700
crossref_primary_10_1038_s41598_020_60991_7
crossref_primary_10_1039_D4FO01269K
crossref_primary_10_3390_nu15102361
crossref_primary_10_1111_jcmm_18014
crossref_primary_10_1177_11786388221141174
crossref_primary_10_1186_s12876_024_03356_y
crossref_primary_10_1186_s13643_023_02299_x
crossref_primary_10_1002_mnfr_202100108
crossref_primary_10_1007_s13205_022_03127_0
crossref_primary_10_1016_j_advnut_2024_100265
crossref_primary_10_1053_j_gastro_2020_10_025
crossref_primary_10_1590_s0004_2803_202000000_72
crossref_primary_10_3390_nu15245025
crossref_primary_10_4103_epj_epj_222_23
crossref_primary_10_1016_j_clnesp_2024_10_153
crossref_primary_10_3390_jmp5020014
crossref_primary_10_1016_j_clnesp_2024_07_1024
crossref_primary_10_1016_j_ebiom_2024_105483
crossref_primary_10_1021_acs_jafc_2c05591
crossref_primary_10_3390_nu15061400
crossref_primary_10_1080_09637486_2024_2334070
crossref_primary_10_3390_life11020117
crossref_primary_10_3390_ph17111480
crossref_primary_10_1016_j_foohum_2024_100423
crossref_primary_10_3390_nu14173462
crossref_primary_10_1007_s12649_021_01408_y
crossref_primary_10_1016_j_micres_2024_127960
crossref_primary_10_3389_fmicb_2023_1296447
crossref_primary_10_1016_j_clnesp_2022_06_006
crossref_primary_10_15212_CVIA_2022_0019
crossref_primary_10_3390_nu12071921
crossref_primary_10_3390_ijms232315421
crossref_primary_10_1038_s41430_022_01189_0
crossref_primary_10_1186_s13098_020_00587_3
crossref_primary_10_20517_mrr_2024_52
crossref_primary_10_3390_nu16132089
crossref_primary_10_1080_19490976_2020_1712984
crossref_primary_10_1186_s12263_024_00743_8
crossref_primary_10_1097_MCO_0000000000000636
crossref_primary_10_3390_metabo12010039
crossref_primary_10_1097_QCO_0000000000000759
crossref_primary_10_3390_ijerph16173128
Cites_doi 10.1111/apt.12758
10.1016/j.nut.2015.09.003
10.1017/S0007114517000204
10.3748/wjg.v19.i40.6911
10.1186/s12906-015-0952-5
10.1017/S0007114514004097
10.2337/dc14-2690
10.1080/14767058.2017.1310193
10.1016/j.clnu.2016.08.015
10.1016/j.nutres.2015.05.008
10.3945/ajcn.115.123216
10.1016/j.nut.2009.05.008
10.1111/ijpo.12273
10.1093/ajcn/76.6.1249
10.5812/ircmj.42902
10.1038/sj.ejcn.1600722
10.3389/fnagi.2016.00256
10.1080/07315724.2013.874937
10.1016/j.nut.2013.12.004
10.3945/ajcn.113.079723
10.1017/S0007114509993801
10.1017/jns.2016.12
10.1016/j.clnu.2013.05.015
10.1017/S0007114516003457
10.1155/2016/5190846
10.3920/BM2014.0035
10.1038/nm.4345
10.1016/0197-2456(86)90046-2
10.1515/jpem-2016-0230
10.1016/j.ebiom.2016.10.036
10.1038/nrgastro.2014.66
10.15171/mejdd.2017.66
10.1017/S0007114514000919
10.1016/j.jacc.2013.11.004
10.1017/jns.2015.5
10.1055/s-0042-105441
10.1159/000365153
10.1016/j.clnu.2015.11.011
10.1139/apnm-2017-0464
10.1002/dmrr.2970
10.3168/jds.2012-5863
10.1530/EJE-14-0554
10.4103/2008-7802.178533
10.1007/s00394-016-1199-8
10.1016/j.copbio.2014.10.006
10.1186/1475-2891-12-138
10.1111/obr.12626
10.1080/07315724.2005.10719473
10.1038/nature12506
10.1007/s13300-017-0226-y
10.1111/dom.12861
10.1038/s41598-017-12535-9
10.3109/09637486.2013.775224
10.1017/S0007114513003875
10.1038/ismej.2014.99
10.1038/ejcn.2016.17
0161910/AIM.004
10.1186/s12937-017-0261-6
10.12938/bmfh.2016-002
10.1177/1074248414555004
10.1186/1476-511X-13-36
10.1038/nature12480
10.1038/ejcn.2012.189
10.1038/ejcn.2013.294
10.1007/s12602-016-9233-y
10.1111/1753-0407.12232
10.1002/oby.21671
10.1097/MPG.0b013e31821f9b85
10.1017/S0007114508111461
10.1016/j.jff.2015.08.031
10.1016/j.ajog.2015.02.008
10.1097/MPG.0b013e318263066c
10.1017/S0007114517000885
10.1186/s40200-017-0304-8
10.12659/MSM.902600
10.4082/kjfm.2013.34.2.80
10.1017/S0007114510002874
10.1126/science.aad3503
10.1016/j.jff.2015.10.006
10.12938/bmfh.17-012
10.1056/NEJMoa1014296
10.1080/07315724.2015.1032443
10.3945/ajcn.115.120170
10.1017/S0007114516000076
10.1039/C6FO00993J
10.1017/S0007114513001037
10.1136/bmj.315.7109.629
10.1016/j.clnu.2013.12.006
10.6133/apjcn.082017.03
10.1080/07315724.2015.1031355
10.1136/bmj.327.7414.557
10.1016/j.nut.2015.11.001
10.3920/BM2015.0173
10.1016/j.numecd.2015.05.002
10.1097/MPG.0000000000001422
10.1126/science.1241214
10.2337/dc17-S008
10.1371/journal.pone.0132121
10.1186/s12967-017-1354-x
10.3168/jds.2014-8500
10.1007/s11695-018-3280-2
10.1038/sj.ejcn.1601555
10.1038/nature11450
10.1159/000349922
10.1007/s00394-013-0649-9
10.1016/j.diabet.2016.04.009
10.1186/s41043-015-0034-9
10.1038/sj.ejcn.1600937
10.1016/j.clnu.2010.09.009
10.3945/ajcn.113.068890
10.1007/s12602-017-9325-3
10.1016/j.nut.2011.08.013
10.4103/1735-1995.193178
10.1038/ijo.2017.210
10.1017/S0007114508043808
10.1017/S0007114515001786
10.5681/bi.2014.007
10.1126/science.1208344
10.1111/jdi.12863
10.2307/2533446
10.5812/ircmj.46017
10.1002/oby.21230
10.1038/nature12820
10.1111/1751-2980.12561
10.1038/ejcn.2010.19
10.1002/2211-5463.12024
10.1155/2014/348959
10.1016/j.jff.2012.09.001
10.1155/2014/319215
10.29252/ibj.23.1.68
10.2307/2669529
ContentType Journal Article
Copyright Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
2019 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Distributed under a Creative Commons Attribution 4.0 International License
Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2019
Copyright_xml – notice: Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
– notice: 2019 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Distributed under a Creative Commons Attribution 4.0 International License
– notice: Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2019
DBID 9YT
ACMMV
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7RV
7X7
7XB
88E
88G
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
BTHHO
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
K9-
K9.
KB0
M0R
M0S
M1P
M2M
NAPCQ
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PSYQQ
Q9U
7X8
1XC
VOOES
5PM
DOI 10.1136/bmjopen-2017-017995
DatabaseName BMJ Open Access Journals
BMJ Journals:Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Nursing & Allied Health Database
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Psychology Database (Alumni)
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials - QC
ProQuest Central
BMJ Journals
ProQuest One Community College
ProQuest Central
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
Consumer Health Database
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Consumer Health Database
ProQuest Health & Medical Collection
Medical Database ProQuest
PsycINFO
Nursing & Allied Health Premium
Proquest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest One Psychology
ProQuest Central Basic
MEDLINE - Academic
Hyper Article en Ligne (HAL)
Hyper Article en Ligne (HAL) (Open Access)
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Psychology
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Family Health (Alumni Edition)
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Central Basic
ProQuest Family Health
ProQuest One Academic Eastern Edition
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Psychology Journals (Alumni)
ProQuest Hospital Collection (Alumni)
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest Psychology Journals
ProQuest One Academic UKI Edition
BMJ Journals
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
MEDLINE

Publicly Available Content Database
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: ACMMV
  name: BMJ Journals:Open Access
  url: https://journals.bmj.com/
  sourceTypes: Publisher
– sequence: 4
  dbid: BENPR
  name: ProQuest Central
  url: http://www.proquest.com/pqcentral?accountid=15518
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2044-6055
ExternalDocumentID PMC6475231
oai_HAL_hal_02165922v1
30928918
10_1136_bmjopen_2017_017995
bmjopen
Genre Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review
Journal Article
GrantInformation_xml – fundername: ;
GroupedDBID ---
4.4
53G
5VS
7RV
7X7
7~R
88E
8FI
8FJ
9YT
ABUWG
ACGFS
ACMMV
ADBBV
ADRAZ
AENEX
AFKRA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
AZQEC
BAWUL
BCNDV
BENPR
BKNYI
BPHCQ
BTFSW
BTHHO
BVXVI
CCPQU
DIK
DWQXO
EBS
EJD
FYUFA
GNUQQ
GROUPED_DOAJ
GX1
H13
HMCUK
HYE
HZ~
K9-
KQ8
M0R
M1P
M2M
M48
M~E
NAPCQ
O9-
OK1
PGMZT
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
PSYQQ
RHI
RMJ
RPM
UKHRP
AAYXX
CITATION
PHGZM
CGR
CUY
CVF
ECM
EIF
NPM
PPXIY
3V.
7XB
8FK
K9.
PJZUB
PKEHL
PQEST
PQUKI
PRINS
Q9U
7X8
PUEGO
1XC
VOOES
5PM
ID FETCH-LOGICAL-b506t-b57ce27fc581bd2f53111a6f778e7e49b8e63081d21996856b1e173871bde14f3
IEDL.DBID 9YT
ISSN 2044-6055
IngestDate Thu Aug 21 13:56:59 EDT 2025
Fri Sep 12 12:36:14 EDT 2025
Thu Sep 04 17:37:53 EDT 2025
Fri Jul 25 21:01:26 EDT 2025
Sun Jul 13 02:58:33 EDT 2025
Tue Jul 01 02:59:37 EDT 2025
Thu Apr 24 23:09:26 EDT 2025
Fri Apr 25 03:31:54 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Keywords lactobacillus
non-alcoholic fatty liver disease
diabetes
bifidobacterium
obesity
probiotics
Language English
License This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-b506t-b57ce27fc581bd2f53111a6f778e7e49b8e63081d21996856b1e173871bde14f3
Notes ObjectType-Article-1
ObjectType-Evidence Based Healthcare-3
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ObjectType-Undefined-3
PMCID: PMC6475231
ORCID 0000-0003-4619-6785
OpenAccessLink http://dx.doi.org/10.1136/bmjopen-2017-017995
PMID 30928918
PQID 2200127204
PQPubID 2040975
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475231
hal_primary_oai_HAL_hal_02165922v1
proquest_miscellaneous_2201711735
proquest_journals_2200127204
pubmed_primary_30928918
crossref_citationtrail_10_1136_bmjopen_2017_017995
crossref_primary_10_1136_bmjopen_2017_017995
bmj_primary_10_1136_bmjopen_2017_017995
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20190330
PublicationDateYYYYMMDD 2019-03-30
PublicationDate_xml – month: 3
  year: 2019
  text: 20190330
  day: 30
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
– name: London
– name: BMA House, Tavistock Square, London, WC1H 9JR
PublicationTitle BMJ open
PublicationTitleAlternate BMJ Open
PublicationYear 2019
Publisher BMJ Publishing Group LTD
BMJ Publishing Group
Publisher_xml – name: BMJ Publishing Group LTD
– name: BMJ Publishing Group
References Cani, Van Hul 2015; 32
David, Maurice, Carmody 2014; 505
Behrouz, Jazayeri, Aryaeian 2017; 9
Lindsay, Brennan, Kennelly 2015; 212
Firouzi, Majid, Ismail 2017; 56
Karbaschian, Mokhtari, Pazouki 2018; 28
Manzhalii, Virchenko, Falalyeyeva 2017; 18
Higashikawa, Noda, Awaya 2016; 70
Hütt, Songisepp, Rätsep 2015; 6
Mobini, Tremaroli, Ståhlman 2017; 19
Asemi, Zare, Shakeri 2013; 63
Hariri, Salehi, Feizi 2015; 11
Tajadadi-Ebrahimi, Bahmani, Shakeri 2014; 65
Ridaura, Faith, Rey 2013; 341
Sharafedtinov, Plotnikova, Alexeeva 2013; 12
Agerholm-Larsen, Raben, Haulrik 2000; 54
Yao, Zeng, He 2017; 23
Begg, Mazumdar 1994; 50
Karamali, Dadkhah, Sadrkhanlou 2016; 42
Duval, Tweedie 2000; 95
Mohseni, Bayani, Bahmani 2018; 34
Vajro, Mandato, Licenziati 2011; 52
Sabico, Al-Mashharawi, Al-Daghri 2017; 15
Hill, Guarner, Reid 2014; 11
Nabavi, Rafraf, Somi 2015; 18
DerSimonian, Laird 1986; 7
Osterberg, Boutagy, McMillan 2015; 23
Ahn, Kim, Ahn 2015; 25
Hove, Brøns, Færch 2015; 172
Mohamadshahi, Veissi, Haidari 2014; 4
Tripolt, Leber, Blattl 2013; 96
Jung, Lee, Kang 2013; 34
Gøbel, Larsen, Jakobsen 2012; 55
Hulston, Churnside, Venables 2015; 113
Andreasen, Larsen, Pedersen-Skovsgaard 2010; 104
Ebrahimi, Nasli-Esfahani, Nadjarzade 2017; 16
Akbari, Asemi, Daneshvar Kakhaki 2016; 8
Sanchez, Darimont, Drapeau 2014; 111
Odamaki, Kato, Sugahara 2016; 7
Naito, Yoshida, Kunihiro 2018; 37
Takahashi, Anzawa, Takami 2016; 35
Zhang, Fang, Zhang 2017; 8
Ilmonen, Isolauri, Poussa 2011; 30
Asgharian, Askari, Esmailzade 2016; 7
Higgins, Thompson, Deeks 2003; 327
Asgharian, Mohammadi, Gholi 2017; 19
Javadi, Ghavami, Khoshbaten 2017; 19
Zarrati, Salehi, Nourijelyani 2014; 33
Jafarnejad, Saremi, Jafarnejad 2016; 2016
Jensen, Ryan, Apovian 2014; 63
Inoue, Shirai, Ochiai 2003; 57
Mahboobi, Iraj, Maghsoudi 2014; 5
Lee, Ba, Roberts 2017; 16
Bernini, Simão, Alfieri 2016; 32
Ivey, Hodgson, Kerr 2014; 68
Eslamparast, Poustchi, Zamani 2014; 99
Higashikawa, Noda, Awaya 2010; 26
Javadi, Khoshbaten, Safaiyan 2017; 4
2018; 16
Ahmadi, Jamilian, Tajabadi-Ebrahimi 2016; 116
Sato, Kanazawa, Azuma 2017; 7
2017; 40
Dolatkhah, Hajifaraji, Abbasalizadeh 2015; 33
Su, Liu, Li 2015; 7
Asemi, Khorrami-Rad, Alizadeh 2014; 33
Ibrahim, Muhamad, Ooi 2018; 43
Sepideh, Karim, Hossein 2016; 35
Wu, Chen, Hoffmann 2011; 334
Aihara, Kajimoto, Hirata 2005; 24
Burton, Rosikiewicz, Pimentel 2017; 117
Barreto, Colado Simão, Morimoto 2014; 30
Gomes, de Sousa, Botelho 2017; 25
Ogawa, Kadooka, Kato 2014; 13
Tajabadi-Ebrahimi, Sharifi, Farrokhian 2017; 125
Wang, Tang, Zhang 2015; 9
Laitinen, Poussa, Isolauri 2009; 101
Mazloom, Yousefinejad, Dabbaghmanesh 2013; 38
Ruan, Sun, He 2015; 10
Firouzi, Mohd-Yusof, Majid 2015; 15
Lee, Bose, Seo 2014; 33
Lindsay, Kennelly, Culliton 2014; 99
Kawano, Miyoshi, Ogawa 2016; 5
Park, Bae 2015; 35
Jones, Alderete, Martin 2018; 13
Kadooka, Sato, Imaizumi 2010; 64
Egger, Davey Smith, Schneider 1997; 315
Le Chatelier, Nielsen, Qin 2013; 500
Minami, Kondo, Yanagisawa 2015; 4
Stenman, Lehtinen, Meland 2016; 13
Hamad, Sato, Uzu 2009; 101
Chung, Yu, Lee 2016; 6
Khalili, Alipour, Asghari Jafar-Abadi 2019; 23
Akkasheh, Kashani-Poor, Tajabadi-Ebrahimi 2016; 32
Kouchaki, Tamtaji, Salami 2017; 36
Sadrzadeh-Yeganeh, Elmadfa, Djazayery 2010; 103
Wang, Juan, He 2017; 30
Ostadrahimi, Taghizadeh, Mobasseri 2015; 44
Simon, Strassburger, Nowotny 2015; 38
Jung, Lee, Kim 2015; 19
Madjd, Taylor, Mousavi 2016; 103
Rajkumar, Mahmood, Kumar 2014; 2014
Qin, Li, Cai 2012; 490
Asemi, Samimi, Tabassi 2013; 67
de Roos, Schouten, Katan 1999; 53
Kijmanawat, Panburana, Reutrakul 2019; 10
Shavakhi, Minakari, Firouzian 2013; 4
Jamilian, Bahmani, Vahedpoor 2016; 19
Omar, Chan, Jones 2013; 5
Aller, De Luis, Izaola 2011; 15
Naruszewicz, Johansson, Zapolska-Downar 2002; 76
Sherf-Dagan, Zelber-Sagi, Zilberman-Schapira 2018; 42
Sun, Buys 2016; 115
Nabavi, Rafraf, Somi 2014; 97
Ma, Li, Yu 2013; 19
Cotillard, Kennedy, Kong 2013; 500
Famouri, Shariat, Hashemipour 2017; 64
Panwar, Calderwood, Grant 2014; 53
Badehnoosh, Karamali, Zarrati 2018; 31
Mofidi, Poustchi, Yari 2017; 117
Bahmani, Tajadadi-Ebrahimi, Kolahdooz 2016; 35
Safavi, Farajian, Kelishadi 2013; 64
Kim, Kim, Kang 2017; 8
Falony, Joossens, Vieira-Silva 2016; 352
Gijsbers, Ding, Malik 2016; 103
Ekhlasi, Kolahdouz Mohammadi, Agah 2016; 21
Eslamparast, Zamani, Hekmatdoost 2014; 112
Borgeraas, Johnson, Skattebu 2018; 19
Wu, Esteve, Tremaroli 2017; 23
Feizollahzadeh, Ghiasvand, Rezaei 2017; 9
Ejtahed, Mohtadi-Nia, Homayouni-Rad 2012; 28
Rajkumar, Kumar, Das 2015; 20
Miraghajani, Zaghian, Dehkohneh 2017
Tonucci, Olbrich Dos Santos, Licursi de Oliveira 2017; 36
Brahe, Le Chatelier, Prifti 2015; 114
Kadooka, Sato, Ogawa 2013; 110
Mozaffarian, Hao, Rimm 2011; 364
Alisi, Bedogni, Baviera 2014; 39
Hajifaraji, Jahanjou, Abbasalizadeh 2018; 27
Akkasheh (2024051615022080000_9.3.e017995.30) 2016; 32
Aller (2024051615022080000_9.3.e017995.32) 2011; 15
2024051615022080000_9.3.e017995.38
Kim (2024051615022080000_9.3.e017995.84) 2017; 8
Lee (2024051615022080000_9.3.e017995.88) 2017; 16
2024051615022080000_9.3.e017995.34
2024051615022080000_9.3.e017995.35
Tajadadi-Ebrahimi (2024051615022080000_9.3.e017995.122) 2014; 65
2024051615022080000_9.3.e017995.33
Higashikawa (2024051615022080000_9.3.e017995.63) 2016; 70
Gomes (2024051615022080000_9.3.e017995.59) 2017; 25
2024051615022080000_9.3.e017995.31
Mohseni (2024051615022080000_9.3.e017995.100) 2018; 34
Feizollahzadeh (2024051615022080000_9.3.e017995.55) 2017; 9
Jung (2024051615022080000_9.3.e017995.77) 2015; 19
Karamali (2024051615022080000_9.3.e017995.80) 2016; 42
Nabavi (2024051615022080000_9.3.e017995.102) 2015; 18
Ekhlasi (2024051615022080000_9.3.e017995.51) 2016; 21
2024051615022080000_9.3.e017995.47
Hariri (2024051615022080000_9.3.e017995.61) 2015; 11
2024051615022080000_9.3.e017995.48
2024051615022080000_9.3.e017995.136
2024051615022080000_9.3.e017995.44
2024051615022080000_9.3.e017995.135
2024051615022080000_9.3.e017995.41
Stenman (2024051615022080000_9.3.e017995.121) 2016; 13
2024051615022080000_9.3.e017995.138
Cani (2024051615022080000_9.3.e017995.10) 2015; 32
Ridaura (2024051615022080000_9.3.e017995.7) 2013; 341
Ostadrahimi (2024051615022080000_9.3.e017995.108) 2015; 44
2024051615022080000_9.3.e017995.131
2024051615022080000_9.3.e017995.134
2024051615022080000_9.3.e017995.133
Mozaffarian (2024051615022080000_9.3.e017995.132) 2011; 364
Yao (2024051615022080000_9.3.e017995.17) 2017; 23
Naito (2024051615022080000_9.3.e017995.103) 2018; 37
2024051615022080000_9.3.e017995.139
2024051615022080000_9.3.e017995.19
Hajifaraji (2024051615022080000_9.3.e017995.60) 2018; 27
2024051615022080000_9.3.e017995.130
2024051615022080000_9.3.e017995.14
2024051615022080000_9.3.e017995.15
Mohamadshahi (2024051615022080000_9.3.e017995.99) 2014; 4
2024051615022080000_9.3.e017995.13
Behrouz (2024051615022080000_9.3.e017995.42) 2017; 9
2024051615022080000_9.3.e017995.98
2024051615022080000_9.3.e017995.11
2024051615022080000_9.3.e017995.96
2024051615022080000_9.3.e017995.127
2024051615022080000_9.3.e017995.97
Sabico (2024051615022080000_9.3.e017995.112) 2017; 15
2024051615022080000_9.3.e017995.126
Badehnoosh (2024051615022080000_9.3.e017995.39) 2018; 31
2024051615022080000_9.3.e017995.120
Firouzi (2024051615022080000_9.3.e017995.57) 2015; 15
2024051615022080000_9.3.e017995.91
Jafarnejad (2024051615022080000_9.3.e017995.71) 2016; 2016
2024051615022080000_9.3.e017995.129
Osterberg (2024051615022080000_9.3.e017995.109) 2015; 23
2024051615022080000_9.3.e017995.9
Tajabadi-Ebrahimi (2024051615022080000_9.3.e017995.123) 2017; 125
2024051615022080000_9.3.e017995.8
Eslamparast (2024051615022080000_9.3.e017995.53) 2014; 112
2024051615022080000_9.3.e017995.2
2024051615022080000_9.3.e017995.1
2024051615022080000_9.3.e017995.28
2024051615022080000_9.3.e017995.6
2024051615022080000_9.3.e017995.25
2024051615022080000_9.3.e017995.5
2024051615022080000_9.3.e017995.4
2024051615022080000_9.3.e017995.23
2024051615022080000_9.3.e017995.3
2024051615022080000_9.3.e017995.24
2024051615022080000_9.3.e017995.21
2024051615022080000_9.3.e017995.114
2024051615022080000_9.3.e017995.22
2024051615022080000_9.3.e017995.113
Javadi (2024051615022080000_9.3.e017995.74) 2017; 4
2024051615022080000_9.3.e017995.20
2024051615022080000_9.3.e017995.110
Akbari (2024051615022080000_9.3.e017995.29) 2016; 8
Ruan (2024051615022080000_9.3.e017995.12) 2015; 10
2024051615022080000_9.3.e017995.111
2024051615022080000_9.3.e017995.117
Sato (2024051615022080000_9.3.e017995.115) 2017; 7
2024051615022080000_9.3.e017995.119
Asemi (2024051615022080000_9.3.e017995.36) 2013; 63
2024051615022080000_9.3.e017995.78
2024051615022080000_9.3.e017995.79
2024051615022080000_9.3.e017995.76
2024051615022080000_9.3.e017995.73
2024051615022080000_9.3.e017995.101
Kawano (2024051615022080000_9.3.e017995.137) 2016; 5
Hütt (2024051615022080000_9.3.e017995.66) 2015; 6
Mahboobi (2024051615022080000_9.3.e017995.92) 2014; 5
2024051615022080000_9.3.e017995.107
2024051615022080000_9.3.e017995.106
Ahn (2024051615022080000_9.3.e017995.27) 2015; 25
Jones (2024051615022080000_9.3.e017995.75) 2018; 13
Ahmadi (2024051615022080000_9.3.e017995.26) 2016; 116
Chung (2024051615022080000_9.3.e017995.46) 2016; 6
2024051615022080000_9.3.e017995.89
2024051615022080000_9.3.e017995.87
Sepideh (2024051615022080000_9.3.e017995.116) 2016; 35
2024051615022080000_9.3.e017995.85
2024051615022080000_9.3.e017995.86
2024051615022080000_9.3.e017995.83
2024051615022080000_9.3.e017995.82
Jamilian (2024051615022080000_9.3.e017995.72) 2016; 19
Bernini (2024051615022080000_9.3.e017995.43) 2016; 32
Takahashi (2024051615022080000_9.3.e017995.124) 2016; 35
Ebrahimi (2024051615022080000_9.3.e017995.49) 2017; 16
Lindsay (2024051615022080000_9.3.e017995.90) 2015; 212
2024051615022080000_9.3.e017995.58
Burton (2024051615022080000_9.3.e017995.45) 2017; 117
2024051615022080000_9.3.e017995.56
Tonucci (2024051615022080000_9.3.e017995.125) 2017; 36
Ivey (2024051615022080000_9.3.e017995.70) 2014; 68
2024051615022080000_9.3.e017995.52
Minami (2024051615022080000_9.3.e017995.95) 2015; 4
2024051615022080000_9.3.e017995.50
Mazloom (2024051615022080000_9.3.e017995.94) 2013; 38
Zarrati (2024051615022080000_9.3.e017995.128) 2014; 33
Shavakhi (2024051615022080000_9.3.e017995.118) 2013; 4
Asgharian (2024051615022080000_9.3.e017995.37) 2016; 7
Bahmani (2024051615022080000_9.3.e017995.40) 2016; 35
Famouri (2024051615022080000_9.3.e017995.54) 2017; 64
Manzhalii (2024051615022080000_9.3.e017995.93) 2017; 18
Karbaschian (2024051615022080000_9.3.e017995.81) 2018; 28
Ibrahim (2024051615022080000_9.3.e017995.67) 2018; 43
(2024051615022080000_9.3.e017995.18) 2018; 16
2024051615022080000_9.3.e017995.69
Naruszewicz (2024051615022080000_9.3.e017995.104) 2002; 76
2024051615022080000_9.3.e017995.68
2024051615022080000_9.3.e017995.65
Odamaki (2024051615022080000_9.3.e017995.105) 2016; 7
2024051615022080000_9.3.e017995.64
2024051615022080000_9.3.e017995.62
Wang (2024051615022080000_9.3.e017995.16) 2017; 30
References_xml – volume: 39
  start-page: 1276
  year: 2014
  article-title: Randomised clinical trial: the beneficial effects of VSL#3 in obese children with non-alcoholic steatohepatitis
  publication-title: Aliment Pharmacol Ther
  doi: 10.1111/apt.12758
– volume: 32
  start-page: 315
  year: 2016
  article-title: Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial
  publication-title: Nutrition
  doi: 10.1016/j.nut.2015.09.003
– volume: 117
  start-page: 662
  year: 2017
  article-title: Synbiotic supplementation in lean patients with non-alcoholic fatty liver disease: a pilot, randomised, double-blind, placebo-controlled, clinical trial
  publication-title: Br J Nutr
  doi: 10.1017/S0007114517000204
– volume: 19
  start-page: 6911
  year: 2013
  article-title: Effects of probiotics on nonalcoholic fatty liver disease: a meta-analysis
  publication-title: World J Gastroenterol
  doi: 10.3748/wjg.v19.i40.6911
– volume: 15
  year: 2015
  article-title: Effect of microbial cell preparation on renal profile and liver function among type 2 diabetics: a randomized controlled trial
  publication-title: BMC Complement Altern Med
  doi: 10.1186/s12906-015-0952-5
– volume: 113
  start-page: 596
  year: 2015
  article-title: Probiotic supplementation prevents high-fat, overfeeding-induced insulin resistance in human subjects
  publication-title: Br J Nutr
  doi: 10.1017/S0007114514004097
– volume: 38
  start-page: 1827
  year: 2015
  article-title: Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept
  publication-title: Diabetes Care
  doi: 10.2337/dc14-2690
– volume: 31
  start-page: 1128
  year: 2018
  article-title: The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes
  publication-title: The Journal of Maternal-Fetal & Neonatal Medicine
  doi: 10.1080/14767058.2017.1310193
– volume: 36
  start-page: 1245
  year: 2017
  article-title: Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled trial
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2016.08.015
– volume: 35
  start-page: 566
  year: 2015
  article-title: Probiotics for weight loss: a systematic review and meta-analysis
  publication-title: Nutr Res
  doi: 10.1016/j.nutres.2015.05.008
– volume: 103
  start-page: 1111
  year: 2016
  article-title: Consumption of dairy foods and diabetes incidence: a dose-response meta-analysis of observational studies
  publication-title: Am J Clin Nutr
  doi: 10.3945/ajcn.115.123216
– volume: 26
  start-page: 367
  year: 2010
  article-title: Improvement of constipation and liver function by plant-derived lactic acid bacteria: a double-blind, randomized trial
  publication-title: Nutrition
  doi: 10.1016/j.nut.2009.05.008
– volume: 4
  start-page: 131
  year: 2017
  article-title: The potential role of probiotics or/and prebiotic on serum lipid profile and insulin resistance in alcoholic fatty liver disease: A double blind randomized clinical trial
  publication-title: Crescent Journal of Medical and Biological Sciences
– volume: 13
  start-page: 705
  year: 2018
  article-title: Probiotic supplementation increases obesity with no detectable effects on liver fat or gut microbiota in obese Hispanic adolescents: a 16-week, randomized, placebo-controlled trial
  publication-title: Pediatr Obes
  doi: 10.1111/ijpo.12273
– volume: 76
  start-page: 1249
  year: 2002
  article-title: Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/76.6.1249
– volume: 19
  year: 2017
  article-title: The effect of synbiotic supplementation on body composition and lipid profile in patients with nafld: a randomized, double blind, placebo-controlled clinical trial study
  publication-title: Iranian Red Crescent Medical Journal
  doi: 10.5812/ircmj.42902
– volume: 53
  start-page: 277
  year: 1999
  article-title: Yoghurt enriched with Lactobacillus acidophilus does not lower blood lipids in healthy men and women with normal to borderline high serum cholesterol levels
  publication-title: Eur J Clin Nutr
  doi: 10.1038/sj.ejcn.1600722
– volume: 8
  start-page: 256
  year: 2016
  article-title: Effect of probiotic supplementation on cognitive function and metabolic status in alzheimer’s disease: a randomized, double-blind and controlled trial
  publication-title: Front Aging Neurosci
  doi: 10.3389/fnagi.2016.00256
– volume: 33
  start-page: 417
  year: 2014
  article-title: Effects of probiotic yogurt on fat distribution and gene expression of proinflammatory factors in peripheral blood mononuclear cells in overweight and obese people with or without weight-loss diet
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2013.874937
– volume: 30
  start-page: 939
  year: 2014
  article-title: Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome
  publication-title: Nutrition
  doi: 10.1016/j.nut.2013.12.004
– volume: 99
  start-page: 1432
  year: 2014
  article-title: Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study)
  publication-title: Am J Clin Nutr
  doi: 10.3945/ajcn.113.079723
– volume: 103
  start-page: 1778
  year: 2010
  article-title: The effects of probiotic and conventional yoghurt on lipid profile in women
  publication-title: Br J Nutr
  doi: 10.1017/S0007114509993801
– volume: 5
  start-page: e23
  year: 2016
  article-title: Lactobacillus gasseri SBT2055 inhibits adipose tissue inflammation and intestinal permeability in mice fed a high-fat diet
  publication-title: J Nutr Sci
  doi: 10.1017/jns.2016.12
– volume: 33
  start-page: 198
  year: 2014
  article-title: Effects of synbiotic food consumption on metabolic status of diabetic patients: a double-blind randomized cross-over controlled clinical trial
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2013.05.015
– volume: 116
  start-page: 1394
  year: 2016
  article-title: The effects of synbiotic supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes: a randomised, double-blind, placebo-controlled trial
  publication-title: Br J Nutr
  doi: 10.1017/S0007114516003457
– volume: 2016
  start-page: 1
  year: 2016
  article-title: Effects of a multispecies probiotic mixture on glycemic control and inflammatory status in women with gestational diabetes: a randomized controlled clinical trial
  publication-title: J Nutr Metab
  doi: 10.1155/2016/5190846
– volume: 6
  start-page: 233
  year: 2015
  article-title: Impact of probiotic Lactobacillus plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults
  publication-title: Benef Microbes
  doi: 10.3920/BM2014.0035
– volume: 23
  start-page: 850
  year: 2017
  article-title: Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
  publication-title: Nat Med
  doi: 10.1038/nm.4345
– volume: 7
  start-page: 177
  year: 1986
  article-title: Meta-analysis in clinical trials
  publication-title: Control Clin Trials
  doi: 10.1016/0197-2456(86)90046-2
– volume: 95
  start-page: 89
  year: 2000
  article-title: A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis
  publication-title: J Am Stat Assoc
– volume: 30
  start-page: 611
  year: 2017
  article-title: Multiple effects of probiotics on different types of diabetes: a systematic review and meta-analysis of randomized, placebo-controlled trials
  publication-title: J Pediatr Endocrinol Metab
  doi: 10.1515/jpem-2016-0230
– volume: 23
  year: 2019
  article-title: The effects of lactobacillus casei on glycemic response, serum sirtuin1 and fetuin-a levels in patients with type 2 diabetes mellitus: a randomized controlled trial
  publication-title: Iran Biomed J
– volume: 13
  start-page: 190
  year: 2016
  article-title: Probiotic with or without fiber controls body fat mass, associated with serum zonulin, in overweight and obese adults-randomized controlled trial
  publication-title: EBioMedicine
  doi: 10.1016/j.ebiom.2016.10.036
– volume: 11
  start-page: 506
  year: 2014
  article-title: Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic
  publication-title: Nat Rev Gastroenterol Hepatol
  doi: 10.1038/nrgastro.2014.66
– volume: 9
  start-page: 150
  year: 2017
  article-title: Effects of probiotic and prebiotic supplementation on leptin, adiponectin, and glycemic parameters in non-alcoholic fatty liver disease: a randomized clinical trial
  publication-title: Middle East J Dig Dis
  doi: 10.15171/mejdd.2017.66
– volume: 112
  start-page: 438
  year: 2014
  article-title: Effects of synbiotic supplementation on insulin resistance in subjects with the metabolic syndrome: a randomised, double-blind, placebo-controlled pilot study
  publication-title: Br J Nutr
  doi: 10.1017/S0007114514000919
– volume: 63
  start-page: 2985
  issue: 25 Pt B
  year: 2014
  article-title: 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2013.11.004
– volume: 4
  year: 2015
  article-title: Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial
  publication-title: J Nutr Sci
  doi: 10.1017/jns.2015.5
– volume: 125
  start-page: 21
  year: 2017
  article-title: A randomized controlled clinical trial investigating the effect of synbiotic administration on markers of insulin metabolism and lipid profiles in overweight type 2 diabetic patients with coronary heart disease
  publication-title: Exp Clin Endocrinol Diabetes
  doi: 10.1055/s-0042-105441
– volume: 65
  start-page: 34
  year: 2014
  article-title: Effects of daily consumption of synbiotic bread on insulin metabolism and serum high-sensitivity C-reactive protein among diabetic patients: a double-blind, randomized, controlled clinical trial
  publication-title: Ann Nutr Metab
  doi: 10.1159/000365153
– volume: 36
  start-page: 85
  year: 2017
  article-title: Clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2015.11.011
– volume: 43
  start-page: 180
  year: 2018
  article-title: The effects of combined probiotic ingestion and circuit training on muscular strength and power and cytokine responses in young males
  publication-title: Appl Physiol Nutr Metab
  doi: 10.1139/apnm-2017-0464
– volume: 34
  start-page: e2970
  year: 2018
  article-title: The beneficial effects of probiotic administration on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial
  publication-title: Diabetes Metab Res Rev
  doi: 10.1002/dmrr.2970
– volume: 96
  start-page: 89
  year: 2013
  article-title: Short communication: effect of supplementation with Lactobacillus casei Shirota on insulin sensitivity, β-cell function, and markers of endothelial function and inflammation in subjects with metabolic syndrome--a pilot study
  publication-title: J Dairy Sci
  doi: 10.3168/jds.2012-5863
– volume: 172
  start-page: 11
  year: 2015
  article-title: Effects of 12 weeks of treatment with fermented milk on blood pressure, glucose metabolism and markers of cardiovascular risk in patients with type 2 diabetes: a randomised double-blind placebo-controlled study
  publication-title: Eur J Endocrinol
  doi: 10.1530/EJE-14-0554
– volume: 7
  year: 2016
  article-title: The effect of symbiotic supplementation on liver enzymes, c-reactive protein and ultrasound findings in patients with non-alcoholic fatty liver disease: a clinical trial
  publication-title: Int J Prev Med
  doi: 10.4103/2008-7802.178533
– volume: 56
  year: 2017
  article-title: Effect of multi-strain probiotics (multi-strain microbial cell preparation) on glycemic control and other diabetes-related outcomes in people with type 2 diabetes: a randomized controlled trial
  publication-title: Eur J Nutr
  doi: 10.1007/s00394-016-1199-8
– volume: 32
  start-page: 21
  year: 2015
  article-title: Novel opportunities for next-generation probiotics targeting metabolic syndrome
  publication-title: Curr Opin Biotechnol
  doi: 10.1016/j.copbio.2014.10.006
– volume: 12
  start-page: 138
  year: 2013
  article-title: Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients--a randomized double-blind placebo-controlled pilot study
  publication-title: Nutr J
  doi: 10.1186/1475-2891-12-138
– volume: 19
  year: 2018
  article-title: Effects of probiotics on body weight, body mass index, fat mass and fat percentage in subjects with overweight or obesity: a systematic review and meta-analysis of randomized controlled trials
  publication-title: Obes Rev
  doi: 10.1111/obr.12626
– volume: 24
  start-page: 257
  year: 2005
  article-title: Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2005.10719473
– volume: 500
  start-page: 541
  year: 2013
  article-title: Richness of human gut microbiome correlates with metabolic markers
  publication-title: Nature
  doi: 10.1038/nature12506
– volume: 8
  start-page: 293
  year: 2017
  article-title: Effects of acarbose on the gut microbiota of prediabetic patients: a randomized, double-blind, controlled crossover trial
  publication-title: Diabetes Ther
  doi: 10.1007/s13300-017-0226-y
– volume: 19
  year: 2017
  article-title: Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: a randomized controlled trial
  publication-title: Diabetes Obes Metab
  doi: 10.1111/dom.12861
– volume: 7
  start-page: 12115
  year: 2017
  article-title: Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-12535-9
– volume: 64
  start-page: 687
  year: 2013
  article-title: The effects of synbiotic supplementation on some cardio-metabolic risk factors in overweight and obese children: a randomized triple-masked controlled trial
  publication-title: Int J Food Sci Nutr
  doi: 10.3109/09637486.2013.775224
– volume: 4
  start-page: 531
  year: 2013
  article-title: Effect of a probiotic and metformin on liver aminotransferases in non-alcoholic steatohepatitis: a double blind randomized clinical trial
  publication-title: Int J Prev Med
– volume: 111
  start-page: 1507
  year: 2014
  article-title: Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women
  publication-title: Br J Nutr
  doi: 10.1017/S0007114513003875
– volume: 9
  start-page: 1
  year: 2015
  article-title: Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice
  publication-title: Isme J
  doi: 10.1038/ismej.2014.99
– volume: 70
  start-page: 582
  year: 2016
  article-title: Antiobesity effect of Pediococcus pentosaceus LP28 on overweight subjects: a randomized, double-blind, placebo-controlled clinical trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2016.17
– volume: 19
  start-page: 687
  year: 2016
  article-title: Effects of probiotic supplementation on metabolic status in pregnant women: a randomized, double-blind, placebo-controlled trial
  publication-title: Arch Iran Med
  doi: 0161910/AIM.004
– volume: 16
  year: 2017
  article-title: Effects of Bifidobacterium animalis subsp. lactis BB-12® on the lipid/lipoprotein profile and short chain fatty acids in healthy young adults: a randomized controlled trial
  publication-title: Nutr J
  doi: 10.1186/s12937-017-0261-6
– volume: 35
  start-page: 163
  year: 2016
  article-title: Effect of Bifidobacterium animalis ssp. lactis GCL2505 on visceral fat accumulation in healthy Japanese adults: a randomized controlled trial
  publication-title: Biosci Microbiota Food Health
  doi: 10.12938/bmfh.2016-002
– volume: 20
  start-page: 289
  year: 2015
  article-title: Effect of probiotic lactobacillus salivarius ubl s22 and prebiotic fructo-oligosaccharide on serum lipids, inflammatory markers, insulin sensitivity, and gut bacteria in healthy young volunteers: a randomized controlled single-blind pilot study
  publication-title: J Cardiovasc Pharmacol Ther
  doi: 10.1177/1074248414555004
– volume: 13
  start-page: 36
  year: 2014
  article-title: Lactobacillus gasseri SBT2055 reduces postprandial and fasting serum non-esterified fatty acid levels in Japanese hypertriacylglycerolemic subjects
  publication-title: Lipids Health Dis
  doi: 10.1186/1476-511X-13-36
– volume: 500
  start-page: 585
  year: 2013
  article-title: Dietary intervention impact on gut microbial gene richness
  publication-title: Nature
  doi: 10.1038/nature12480
– volume: 67
  start-page: 71
  year: 2013
  article-title: Effect of daily consumption of probiotic yoghurt on insulin resistance in pregnant women: a randomized controlled trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2012.189
– volume: 68
  start-page: 447
  year: 2014
  article-title: The effects of probiotic bacteria on glycaemic control in overweight men and women: a randomised controlled trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2013.294
– volume: 9
  start-page: 41-47
  year: 2017
  article-title: Effect of probiotic soy milk on serum levels of adiponectin, inflammatory mediators, lipid profile, and fasting blood glucose among patients with type ii diabetes mellitus
  publication-title: Probiotics Antimicrob Proteins
  doi: 10.1007/s12602-016-9233-y
– volume: 7
  start-page: 729
  year: 2015
  article-title: Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in Chinese patients with type 2 diabetes mellitus
  publication-title: J Diabetes
  doi: 10.1111/1753-0407.12232
– volume: 25
  start-page: 30
  year: 2017
  article-title: The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial
  publication-title: Obesity
  doi: 10.1002/oby.21671
– volume: 52
  start-page: 740
  year: 2011
  article-title: Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0b013e31821f9b85
– volume: 101
  start-page: 1679
  year: 2009
  article-title: Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial
  publication-title: Br J Nutr
  doi: 10.1017/S0007114508111461
– volume: 18
  start-page: 684
  year: 2015
  article-title: Probiotic yogurt improves body mass index and fasting insulin levels without affecting serum leptin and adiponectin levels in non-alcoholic fatty liver disease (NAFLD)
  publication-title: J Funct Foods
  doi: 10.1016/j.jff.2015.08.031
– volume: 212
  start-page: 496.e1
  year: 2015
  article-title: Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2015.02.008
– volume: 55
  start-page: 673
  year: 2012
  article-title: Probiotics to adolescents with obesity: effects on inflammation and metabolic syndrome
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0b013e318263066c
– volume: 15
  start-page: 1090
  year: 2011
  article-title: Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial
  publication-title: Eur Rev Med Pharmacol Sci
– volume: 117
  start-page: 1312
  year: 2017
  article-title: Probiotic yogurt and acidified milk similarly reduce postprandial inflammation and both alter the gut microbiota of healthy, young men
  publication-title: Br J Nutr
  doi: 10.1017/S0007114517000885
– volume: 16
  start-page: 23
  year: 2017
  article-title: Effect of symbiotic supplementation on glycemic control, lipid profiles and microalbuminuria in patients with non-obese type 2 diabetes: a randomized, double-blind, clinical trial
  publication-title: J Diabetes Metab Disord
  doi: 10.1186/s40200-017-0304-8
– volume: 23
  start-page: 3044
  year: 2017
  article-title: Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials
  publication-title: Med Sci Monit
  doi: 10.12659/MSM.902600
– volume: 20
  start-page: 289
  year: 2015
  article-title: Effect of Probiotic Lactobacillus salivarius UBL S22 and prebiotic fructo-oligosaccharide on serum lipids, inflammatory markers, insulin sensitivity, and gut bacteria in healthy young volunteers
  publication-title: J Cardiovasc Pharmacol Ther
  doi: 10.1177/1074248414555004
– volume: 34
  start-page: 80
  year: 2013
  article-title: Effect of lactobacillus gasseri bnr17 on overweight and obese adults: a randomized, double-blind clinical trial
  publication-title: Korean J Fam Med
  doi: 10.4082/kjfm.2013.34.2.80
– volume: 104
  start-page: 1831
  year: 2010
  article-title: Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects
  publication-title: Br J Nutr
  doi: 10.1017/S0007114510002874
– volume: 352
  start-page: 560
  year: 2016
  article-title: Population-level analysis of gut microbiome variation
  publication-title: Science
  doi: 10.1126/science.aad3503
– volume: 19
  start-page: 744
  year: 2015
  article-title: Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects
  publication-title: J Funct Foods
  doi: 10.1016/j.jff.2015.10.006
– volume: 37
  start-page: 9
  year: 2018
  article-title: Effect of Lactobacillus casei strain Shirota-fermented milk on metabolic abnormalities in obese prediabetic Japanese men: a randomised, double-blind, placebo-controlled trial
  publication-title: Biosci Microbiota Food Health
  doi: 10.12938/bmfh.17-012
– volume: 364
  start-page: 2392
  year: 2011
  article-title: Changes in diet and lifestyle and long-term weight gain in women and men
  publication-title: N Engl J Med Overseas Ed
  doi: 10.1056/NEJMoa1014296
– volume: 35
  start-page: 506
  year: 2016
  article-title: The consumption of synbiotic bread containing lactobacillus sporogenes and inulin affects nitric oxide and malondialdehyde in patients with type 2 diabetes mellitus: randomized, double-blind, placebo-controlled trial
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2015.1032443
– volume: 103
  start-page: 323
  year: 2016
  article-title: Comparison of the effect of daily consumption of probiotic compared with low-fat conventional yogurt on weight loss in healthy obese women following an energy-restricted diet: a randomized controlled trial
  publication-title: Am J Clin Nutr
  doi: 10.3945/ajcn.115.120170
– volume: 115
  start-page: 1167
  year: 2016
  article-title: Glucose- and glycaemic factor-lowering effects of probiotics on diabetes: a meta-analysis of randomised placebo-controlled trials
  publication-title: Br J Nutr
  doi: 10.1017/S0007114516000076
– volume: 8
  start-page: 250
  year: 2017
  article-title: Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals
  publication-title: Food Funct
  doi: 10.1039/C6FO00993J
– volume: 110
  start-page: 1696
  year: 2013
  article-title: Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial
  publication-title: Br J Nutr
  doi: 10.1017/S0007114513001037
– volume: 315
  start-page: 629
  year: 1997
  article-title: Bias in meta-analysis detected by a simple, graphical test
  publication-title: BMJ
  doi: 10.1136/bmj.315.7109.629
– volume: 33
  start-page: 973
  year: 2014
  article-title: The effects of co-administration of probiotics with herbal medicine on obesity, metabolic endotoxemia and dysbiosis: a randomized double-blind controlled clinical trial
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2013.12.006
– volume: 5
  start-page: 1239
  year: 2014
  article-title: The effects of probiotic supplementation on markers of blood lipids, and blood pressure in patients with prediabetes: a randomized clinical trial
  publication-title: Int J Prev Med
– volume: 27
  start-page: 581
  year: 2018
  article-title: Effect of probiotic supplements in women with gestational diabetes mellitus on inflammation and oxidative stress biomarkers: a randomized clinical trial
  publication-title: Asia Pac J Clin Nutr
  doi: 10.6133/apjcn.082017.03
– volume: 11
  start-page: 74
  issue: Suppl 1
  year: 2015
  article-title: The effect of probiotic soy milk and soy milk on anthropometric measures and blood pressure in patients with type II diabetes mellitus: A randomized double-blind clinical trial
  publication-title: ARYA Atheroscler
– volume: 35
  start-page: 500
  year: 2016
  article-title: Effects of Multistrain probiotic supplementation on glycemic and inflammatory indices in patients with nonalcoholic fatty liver disease: a double-blind randomized clinical trial
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2015.1031355
– volume: 327
  start-page: 557
  year: 2003
  article-title: Measuring inconsistency in meta-analyses
  publication-title: BMJ
  doi: 10.1136/bmj.327.7414.557
– volume: 32
  start-page: 716
  year: 2016
  article-title: Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: a randomized trial. Effects of probiotics on metabolic syndrome
  publication-title: Nutrition
  doi: 10.1016/j.nut.2015.11.001
– volume: 7
  start-page: 473
  year: 2016
  article-title: Effect of probiotic yoghurt on animal-based diet-induced change in gut microbiota: an open, randomised, parallel-group study
  publication-title: Benef Microbes
  doi: 10.3920/BM2015.0173
– volume: 25
  start-page: 724
  year: 2015
  article-title: The triglyceride-lowering effect of supplementation with dual probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032: Reduction of fasting plasma lysophosphatidylcholines in nondiabetic and hypertriglyceridemic subjects
  publication-title: Nutr Metab Cardiovasc Dis
  doi: 10.1016/j.numecd.2015.05.002
– volume: 64
  start-page: 413
  year: 2017
  article-title: Effects of probiotics on nonalcoholic fatty liver disease in obese children and adolescents
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0000000000001422
– volume: 341
  year: 2013
  article-title: Gut microbiota from twins discordant for obesity modulate metabolism in mice
  publication-title: Science
  doi: 10.1126/science.1241214
– volume: 40
  start-page: S44
  issue: Suppl 1
  year: 2017
  article-title: 5. Prevention or delay of type 2 diabetes
  publication-title: Diabetes Care
  doi: 10.2337/dc17-S008
– volume: 10
  year: 2015
  article-title: Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0132121
– volume: 15
  start-page: 249
  year: 2017
  article-title: Effects of a multi-strain probiotic supplement for 12 weeks in circulating endotoxin levels and cardiometabolic profiles of medication naïve T2DM patients: a randomized clinical trial
  publication-title: J Transl Med
  doi: 10.1186/s12967-017-1354-x
– volume: 97
  start-page: 7386
  year: 2014
  article-title: Effects of probiotic yogurt consumption on metabolic factors in individuals with nonalcoholic fatty liver disease
  publication-title: J Dairy Sci
  doi: 10.3168/jds.2014-8500
– volume: 28
  start-page: 2874
  year: 2018
  article-title: Probiotic supplementation in morbid obese patients undergoing One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) surgery: a randomized, double-blind, placebo-controlled, clinical trial
  publication-title: Obes Surg
  doi: 10.1007/s11695-018-3280-2
– volume: 57
  start-page: 490
  year: 2003
  article-title: Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives
  publication-title: Eur J Clin Nutr
  doi: 10.1038/sj.ejcn.1601555
– volume: 490
  start-page: 55
  year: 2012
  article-title: A metagenome-wide association study of gut microbiota in type 2 diabetes
  publication-title: Nature
  doi: 10.1038/nature11450
– volume: 63
  start-page: 1
  issue: 1-2
  year: 2013
  article-title: Effect of multispecies probiotic supplements on metabolic profiles, hs-CRP, and oxidative stress in patients with type 2 diabetes
  publication-title: Ann Nutr Metab
  doi: 10.1159/000349922
– volume: 53
  start-page: 1465
  year: 2014
  article-title: Lactobacillus strains isolated from infant faeces possess potent inhibitory activity against intestinal alpha- and beta-glucosidases suggesting anti-diabetic potential
  publication-title: Eur J Nutr
  doi: 10.1007/s00394-013-0649-9
– volume: 38
  start-page: 38
  year: 2013
  article-title: Effect of probiotics on lipid profile, glycemic control, insulin action, oxidative stress, and inflammatory markers in patients with type 2 diabetes: a clinical trial
  publication-title: Iran J Med Sci
– volume: 42
  start-page: 234
  year: 2016
  article-title: Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: A randomized, double-blind, placebo-controlled trial
  publication-title: Diabetes Metab
  doi: 10.1016/j.diabet.2016.04.009
– volume: 16
  start-page: e05315
  year: 2018
  publication-title: EFSA Journal
– volume: 33
  start-page: 25
  year: 2015
  article-title: Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial
  publication-title: J Health Popul Nutr
  doi: 10.1186/s41043-015-0034-9
– volume: 54
  start-page: 288
  year: 2000
  article-title: Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases
  publication-title: Eur J Clin Nutr
  doi: 10.1038/sj.ejcn.1600937
– volume: 30
  start-page: 156
  year: 2011
  article-title: Impact of dietary counselling and probiotic intervention on maternal anthropometric measurements during and after pregnancy: a randomized placebo-controlled trial
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2010.09.009
– volume: 99
  start-page: 535
  year: 2014
  article-title: Synbiotic supplementation in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled pilot study
  publication-title: Am J Clin Nutr
  doi: 10.3945/ajcn.113.068890
– year: 2017
  article-title: Probiotic soy milk consumption and renal function among type 2 diabetic patients with nephropathy: a randomized controlled clinical trial
  publication-title: Probiotics Antimicrob Proteins
  doi: 10.1007/s12602-017-9325-3
– volume: 28
  start-page: 539
  year: 2012
  article-title: Probiotic yogurt improves antioxidant status in type 2 diabetic patients
  publication-title: Nutrition
  doi: 10.1016/j.nut.2011.08.013
– volume: 44
  start-page: 228
  year: 2015
  article-title: Effect of probiotic fermented milk (kefir) on glycemic control and lipid profile in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial
  publication-title: Iran J Public Health
– volume: 21
  start-page: 106
  year: 2016
  article-title: Do symbiotic and Vitamin E supplementation have favorite effects in nonalcoholic fatty liver disease? A randomized, double-blind, placebo-controlled trial
  publication-title: J Res Med Sci
  doi: 10.4103/1735-1995.193178
– volume: 42
  year: 2018
  article-title: Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial
  publication-title: Int J Obes
  doi: 10.1038/ijo.2017.210
– volume: 101
  start-page: 716
  year: 2009
  article-title: Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats
  publication-title: Br J Nutr
  doi: 10.1017/S0007114508043808
– volume: 114
  start-page: 406
  year: 2015
  article-title: Dietary modulation of the gut microbiota--a randomised controlled trial in obese postmenopausal women
  publication-title: Br J Nutr
  doi: 10.1017/S0007114515001786
– volume: 4
  start-page: 83
  year: 2014
  article-title: Effects of probiotic yogurt consumption on inflammatory biomarkers in patients with type 2 diabetes
  publication-title: Bioimpacts
  doi: 10.5681/bi.2014.007
– volume: 334
  start-page: 105
  year: 2011
  article-title: Linking long-term dietary patterns with gut microbial enterotypes
  publication-title: Science
  doi: 10.1126/science.1208344
– volume: 10
  year: 2019
  article-title: The effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: a double-blind randomized controlled trial
  publication-title: J Diabetes Investig
  doi: 10.1111/jdi.12863
– volume: 50
  start-page: 1088
  year: 1994
  article-title: Operating characteristics of a rank correlation test for publication bias
  publication-title: Biometrics
  doi: 10.2307/2533446
– volume: 19
  year: 2017
  article-title: The Effect of Probiotic and/or Prebiotic on Liver Function Tests in Patients with Nonalcoholic Fatty Liver Disease: A Double Blind Randomized Clinical Trial
  publication-title: Iran Red Crescent Med J
  doi: 10.5812/ircmj.46017
– volume: 23
  start-page: 2364
  year: 2015
  article-title: Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults
  publication-title: Obesity
  doi: 10.1002/oby.21230
– volume: 505
  start-page: 559
  year: 2014
  article-title: Diet rapidly and reproducibly alters the human gut microbiome
  publication-title: Nature
  doi: 10.1038/nature12820
– volume: 18
  start-page: 698
  year: 2017
  article-title: Treatment efficacy of a probiotic preparation for non-alcoholic steatohepatitis: A pilot trial
  publication-title: J Dig Dis
  doi: 10.1111/1751-2980.12561
– volume: 64
  start-page: 636
  year: 2010
  article-title: Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2010.19
– volume: 6
  start-page: 64
  year: 2016
  article-title: Intestinal removal of free fatty acids from hosts by Lactobacilli for the treatment of obesity
  publication-title: FEBS Open Bio
  doi: 10.1002/2211-5463.12024
– volume: 2014
  start-page: 1
  year: 2014
  article-title: Effect of probiotic (VSL#3) and omega-3 on lipid profile, insulin sensitivity, inflammatory markers, and gut colonization in overweight adults: a randomized, controlled trial
  publication-title: Mediators Inflamm
  doi: 10.1155/2014/348959
– volume: 5
  start-page: 116
  year: 2013
  article-title: Lactobacillus fermentum and Lactobacillus amylovorus as probiotics alter body adiposity and gut microflora in healthy persons
  publication-title: J Funct Foods
  doi: 10.1016/j.jff.2012.09.001
– volume: 32
  start-page: 21
  year: 2015
  ident: 2024051615022080000_9.3.e017995.10
  article-title: Novel opportunities for next-generation probiotics targeting metabolic syndrome
  publication-title: Curr Opin Biotechnol
  doi: 10.1016/j.copbio.2014.10.006
– ident: 2024051615022080000_9.3.e017995.113
  doi: 10.1017/S0007114509993801
– ident: 2024051615022080000_9.3.e017995.56
  doi: 10.1007/s00394-016-1199-8
– ident: 2024051615022080000_9.3.e017995.35
  doi: 10.1038/ejcn.2012.189
– volume: 25
  start-page: 30
  year: 2017
  ident: 2024051615022080000_9.3.e017995.59
  article-title: The additional effects of a probiotic mix on abdominal adiposity and antioxidant Status: A double-blind, randomized trial
  publication-title: Obesity
  doi: 10.1002/oby.21671
– ident: 2024051615022080000_9.3.e017995.15
  doi: 10.1111/obr.12626
– ident: 2024051615022080000_9.3.e017995.64
  doi: 10.1530/EJE-14-0554
– volume: 15
  start-page: 249
  year: 2017
  ident: 2024051615022080000_9.3.e017995.112
  article-title: Effects of a multi-strain probiotic supplement for 12 weeks in circulating endotoxin levels and cardiometabolic profiles of medication naïve T2DM patients: a randomized clinical trial
  publication-title: J Transl Med
  doi: 10.1186/s12967-017-1354-x
– volume: 2016
  start-page: 1
  year: 2016
  ident: 2024051615022080000_9.3.e017995.71
  article-title: Effects of a multispecies probiotic mixture on glycemic control and inflammatory status in women with gestational diabetes: a randomized controlled clinical trial
  publication-title: J Nutr Metab
  doi: 10.1155/2016/5190846
– volume: 6
  start-page: 64
  year: 2016
  ident: 2024051615022080000_9.3.e017995.46
  article-title: Intestinal removal of free fatty acids from hosts by Lactobacilli for the treatment of obesity
  publication-title: FEBS Open Bio
  doi: 10.1002/2211-5463.12024
– volume: 44
  start-page: 228
  year: 2015
  ident: 2024051615022080000_9.3.e017995.108
  article-title: Effect of probiotic fermented milk (kefir) on glycemic control and lipid profile in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial
  publication-title: Iran J Public Health
– volume: 18
  start-page: 684
  year: 2015
  ident: 2024051615022080000_9.3.e017995.102
  article-title: Probiotic yogurt improves body mass index and fasting insulin levels without affecting serum leptin and adiponectin levels in non-alcoholic fatty liver disease (NAFLD)
  publication-title: J Funct Foods
  doi: 10.1016/j.jff.2015.08.031
– volume: 5
  start-page: e23
  year: 2016
  ident: 2024051615022080000_9.3.e017995.137
  article-title: Lactobacillus gasseri SBT2055 inhibits adipose tissue inflammation and intestinal permeability in mice fed a high-fat diet
  publication-title: J Nutr Sci
  doi: 10.1017/jns.2016.12
– volume: 4
  start-page: 531
  year: 2013
  ident: 2024051615022080000_9.3.e017995.118
  article-title: Effect of a probiotic and metformin on liver aminotransferases in non-alcoholic steatohepatitis: a double blind randomized clinical trial
  publication-title: Int J Prev Med
– ident: 2024051615022080000_9.3.e017995.9
  doi: 10.1038/ismej.2014.99
– volume: 19
  start-page: 687
  year: 2016
  ident: 2024051615022080000_9.3.e017995.72
  article-title: Effects of probiotic supplementation on metabolic status in pregnant women: a randomized, double-blind, placebo-controlled trial
  publication-title: Arch Iran Med
– volume: 19
  start-page: 744
  year: 2015
  ident: 2024051615022080000_9.3.e017995.77
  article-title: Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects
  publication-title: J Funct Foods
  doi: 10.1016/j.jff.2015.10.006
– volume: 7
  start-page: 12115
  year: 2017
  ident: 2024051615022080000_9.3.e017995.115
  article-title: Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-12535-9
– ident: 2024051615022080000_9.3.e017995.8
  doi: 10.1038/nrgastro.2014.66
– ident: 2024051615022080000_9.3.e017995.96
  doi: 10.1007/s12602-017-9325-3
– ident: 2024051615022080000_9.3.e017995.120
  doi: 10.2337/dc14-2690
– ident: 2024051615022080000_9.3.e017995.135
  doi: 10.1111/1753-0407.12232
– ident: 2024051615022080000_9.3.e017995.138
  doi: 10.1177/1074248414555004
– ident: 2024051615022080000_9.3.e017995.65
  doi: 10.1017/S0007114514004097
– volume: 18
  start-page: 698
  year: 2017
  ident: 2024051615022080000_9.3.e017995.93
  article-title: Treatment efficacy of a probiotic preparation for non-alcoholic steatohepatitis: A pilot trial
  publication-title: J Dig Dis
  doi: 10.1111/1751-2980.12561
– volume: 31
  start-page: 1128
  year: 2018
  ident: 2024051615022080000_9.3.e017995.39
  article-title: The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes
  publication-title: The Journal of Maternal-Fetal & Neonatal Medicine
  doi: 10.1080/14767058.2017.1310193
– ident: 2024051615022080000_9.3.e017995.52
  doi: 10.3945/ajcn.113.068890
– ident: 2024051615022080000_9.3.e017995.110
  doi: 10.1155/2014/319215
– ident: 2024051615022080000_9.3.e017995.5
  doi: 10.1038/nature12820
– volume: 23
  start-page: 3044
  year: 2017
  ident: 2024051615022080000_9.3.e017995.17
  article-title: Effect of probiotics on glucose and lipid metabolism in type 2 diabetes mellitus: a meta-analysis of 12 randomized controlled trials
  publication-title: Med Sci Monit
  doi: 10.12659/MSM.902600
– ident: 2024051615022080000_9.3.e017995.91
  doi: 10.3945/ajcn.115.120170
– ident: 2024051615022080000_9.3.e017995.97
  doi: 10.1111/dom.12861
– ident: 2024051615022080000_9.3.e017995.22
  doi: 10.2307/2533446
– volume: 16
  start-page: 23
  year: 2017
  ident: 2024051615022080000_9.3.e017995.49
  article-title: Effect of symbiotic supplementation on glycemic control, lipid profiles and microalbuminuria in patients with non-obese type 2 diabetes: a randomized, double-blind, clinical trial
  publication-title: J Diabetes Metab Disord
  doi: 10.1186/s40200-017-0304-8
– ident: 2024051615022080000_9.3.e017995.101
  doi: 10.3168/jds.2014-8500
– volume: 28
  start-page: 2874
  year: 2018
  ident: 2024051615022080000_9.3.e017995.81
  article-title: Probiotic supplementation in morbid obese patients undergoing One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) surgery: a randomized, double-blind, placebo-controlled, clinical trial
  publication-title: Obes Surg
  doi: 10.1007/s11695-018-3280-2
– volume: 43
  start-page: 180
  year: 2018
  ident: 2024051615022080000_9.3.e017995.67
  article-title: The effects of combined probiotic ingestion and circuit training on muscular strength and power and cytokine responses in young males
  publication-title: Appl Physiol Nutr Metab
  doi: 10.1139/apnm-2017-0464
– ident: 2024051615022080000_9.3.e017995.111
  doi: 10.1177/1074248414555004
– volume: 341
  year: 2013
  ident: 2024051615022080000_9.3.e017995.7
  article-title: Gut microbiota from twins discordant for obesity modulate metabolism in mice
  publication-title: Science
  doi: 10.1126/science.1241214
– volume: 30
  start-page: 611
  year: 2017
  ident: 2024051615022080000_9.3.e017995.16
  article-title: Multiple effects of probiotics on different types of diabetes: a systematic review and meta-analysis of randomized, placebo-controlled trials
  publication-title: J Pediatr Endocrinol Metab
  doi: 10.1515/jpem-2016-0230
– ident: 2024051615022080000_9.3.e017995.106
  doi: 10.1186/1476-511X-13-36
– ident: 2024051615022080000_9.3.e017995.2
  doi: 10.1038/nature11450
– ident: 2024051615022080000_9.3.e017995.78
  doi: 10.1038/ejcn.2010.19
– volume: 9
  start-page: 41-47
  year: 2017
  ident: 2024051615022080000_9.3.e017995.55
  article-title: Effect of probiotic soy milk on serum levels of adiponectin, inflammatory mediators, lipid profile, and fasting blood glucose among patients with type ii diabetes mellitus
  publication-title: Probiotics Antimicrob Proteins
  doi: 10.1007/s12602-016-9233-y
– volume: 7
  year: 2016
  ident: 2024051615022080000_9.3.e017995.37
  article-title: The effect of symbiotic supplementation on liver enzymes, c-reactive protein and ultrasound findings in patients with non-alcoholic fatty liver disease: a clinical trial
  publication-title: Int J Prev Med
  doi: 10.4103/2008-7802.178533
– volume: 15
  start-page: 1090
  year: 2011
  ident: 2024051615022080000_9.3.e017995.32
  article-title: Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial
  publication-title: Eur Rev Med Pharmacol Sci
– volume: 38
  start-page: 38
  year: 2013
  ident: 2024051615022080000_9.3.e017995.94
  article-title: Effect of probiotics on lipid profile, glycemic control, insulin action, oxidative stress, and inflammatory markers in patients with type 2 diabetes: a clinical trial
  publication-title: Iran J Med Sci
– ident: 2024051615022080000_9.3.e017995.25
  doi: 10.1038/sj.ejcn.1600937
– volume: 112
  start-page: 438
  year: 2014
  ident: 2024051615022080000_9.3.e017995.53
  article-title: Effects of synbiotic supplementation on insulin resistance in subjects with the metabolic syndrome: a randomised, double-blind, placebo-controlled pilot study
  publication-title: Br J Nutr
  doi: 10.1017/S0007114514000919
– ident: 2024051615022080000_9.3.e017995.23
  doi: 10.1136/bmj.315.7109.629
– volume: 63
  start-page: 1
  issue: 1-2
  year: 2013
  ident: 2024051615022080000_9.3.e017995.36
  article-title: Effect of multispecies probiotic supplements on metabolic profiles, hs-CRP, and oxidative stress in patients with type 2 diabetes
  publication-title: Ann Nutr Metab
  doi: 10.1159/000349922
– volume: 16
  year: 2017
  ident: 2024051615022080000_9.3.e017995.88
  article-title: Effects of Bifidobacterium animalis subsp. lactis BB-12® on the lipid/lipoprotein profile and short chain fatty acids in healthy young adults: a randomized controlled trial
  publication-title: Nutr J
  doi: 10.1186/s12937-017-0261-6
– volume: 4
  start-page: 83
  year: 2014
  ident: 2024051615022080000_9.3.e017995.99
  article-title: Effects of probiotic yogurt consumption on inflammatory biomarkers in patients with type 2 diabetes
  publication-title: Bioimpacts
– ident: 2024051615022080000_9.3.e017995.33
  doi: 10.1017/S0007114510002874
– volume: 32
  start-page: 315
  year: 2016
  ident: 2024051615022080000_9.3.e017995.30
  article-title: Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial
  publication-title: Nutrition
  doi: 10.1016/j.nut.2015.09.003
– volume: 125
  start-page: 21
  year: 2017
  ident: 2024051615022080000_9.3.e017995.123
  article-title: A randomized controlled clinical trial investigating the effect of synbiotic administration on markers of insulin metabolism and lipid profiles in overweight type 2 diabetic patients with coronary heart disease
  publication-title: Exp Clin Endocrinol Diabetes
  doi: 10.1055/s-0042-105441
– ident: 2024051615022080000_9.3.e017995.131
  doi: 10.3945/ajcn.115.123216
– ident: 2024051615022080000_9.3.e017995.19
  doi: 10.1017/S0007114513003875
– ident: 2024051615022080000_9.3.e017995.86
  doi: 10.1017/S0007114508111461
– ident: 2024051615022080000_9.3.e017995.82
  doi: 10.29252/ibj.23.1.68
– volume: 21
  start-page: 106
  year: 2016
  ident: 2024051615022080000_9.3.e017995.51
  article-title: Do symbiotic and Vitamin E supplementation have favorite effects in nonalcoholic fatty liver disease? A randomized, double-blind, placebo-controlled trial
  publication-title: J Res Med Sci
  doi: 10.4103/1735-1995.193178
– volume: 27
  start-page: 581
  year: 2018
  ident: 2024051615022080000_9.3.e017995.60
  article-title: Effect of probiotic supplements in women with gestational diabetes mellitus on inflammation and oxidative stress biomarkers: a randomized clinical trial
  publication-title: Asia Pac J Clin Nutr
– ident: 2024051615022080000_9.3.e017995.76
  doi: 10.4082/kjfm.2013.34.2.80
– volume: 6
  start-page: 233
  year: 2015
  ident: 2024051615022080000_9.3.e017995.66
  article-title: Impact of probiotic Lactobacillus plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults
  publication-title: Benef Microbes
  doi: 10.3920/BM2014.0035
– volume: 65
  start-page: 34
  year: 2014
  ident: 2024051615022080000_9.3.e017995.122
  article-title: Effects of daily consumption of synbiotic bread on insulin metabolism and serum high-sensitivity C-reactive protein among diabetic patients: a double-blind, randomized, controlled clinical trial
  publication-title: Ann Nutr Metab
  doi: 10.1159/000365153
– volume: 42
  start-page: 234
  year: 2016
  ident: 2024051615022080000_9.3.e017995.80
  article-title: Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: A randomized, double-blind, placebo-controlled trial
  publication-title: Diabetes Metab
  doi: 10.1016/j.diabet.2016.04.009
– volume: 212
  start-page: 496.e1
  year: 2015
  ident: 2024051615022080000_9.3.e017995.90
  article-title: Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial
  publication-title: Am J Obstet Gynecol
  doi: 10.1016/j.ajog.2015.02.008
– volume: 364
  start-page: 2392
  year: 2011
  ident: 2024051615022080000_9.3.e017995.132
  article-title: Changes in diet and lifestyle and long-term weight gain in women and men
  publication-title: N Engl J Med Overseas Ed
  doi: 10.1056/NEJMoa1014296
– ident: 2024051615022080000_9.3.e017995.89
  doi: 10.3945/ajcn.113.079723
– volume: 36
  start-page: 85
  year: 2017
  ident: 2024051615022080000_9.3.e017995.125
  article-title: Clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study
  publication-title: Clin Nutr
  doi: 10.1016/j.clnu.2015.11.011
– ident: 2024051615022080000_9.3.e017995.62
  doi: 10.1016/j.nut.2009.05.008
– volume: 9
  start-page: 150
  year: 2017
  ident: 2024051615022080000_9.3.e017995.42
  article-title: Effects of probiotic and prebiotic supplementation on leptin, adiponectin, and glycemic parameters in non-alcoholic fatty liver disease: a randomized clinical trial
  publication-title: Middle East J Dig Dis
  doi: 10.15171/mejdd.2017.66
– volume: 35
  start-page: 500
  year: 2016
  ident: 2024051615022080000_9.3.e017995.116
  article-title: Effects of Multistrain probiotic supplementation on glycemic and inflammatory indices in patients with nonalcoholic fatty liver disease: a double-blind randomized clinical trial
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2015.1031355
– ident: 2024051615022080000_9.3.e017995.134
  doi: 10.1007/s13300-017-0226-y
– ident: 2024051615022080000_9.3.e017995.73
  doi: 10.5812/ircmj.46017
– ident: 2024051615022080000_9.3.e017995.41
  doi: 10.1016/j.nut.2013.12.004
– volume: 34
  start-page: e2970
  year: 2018
  ident: 2024051615022080000_9.3.e017995.100
  article-title: The beneficial effects of probiotic administration on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial
  publication-title: Diabetes Metab Res Rev
  doi: 10.1002/dmrr.2970
– volume: 13
  start-page: 190
  year: 2016
  ident: 2024051615022080000_9.3.e017995.121
  article-title: Probiotic with or without fiber controls body fat mass, associated with serum zonulin, in overweight and obese adults-randomized controlled trial
  publication-title: EBioMedicine
  doi: 10.1016/j.ebiom.2016.10.036
– ident: 2024051615022080000_9.3.e017995.126
  doi: 10.3168/jds.2012-5863
– ident: 2024051615022080000_9.3.e017995.11
  doi: 10.3748/wjg.v19.i40.6911
– volume: 25
  start-page: 724
  year: 2015
  ident: 2024051615022080000_9.3.e017995.27
  article-title: The triglyceride-lowering effect of supplementation with dual probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032: Reduction of fasting plasma lysophosphatidylcholines in nondiabetic and hypertriglyceridemic subjects
  publication-title: Nutr Metab Cardiovasc Dis
  doi: 10.1016/j.numecd.2015.05.002
– ident: 2024051615022080000_9.3.e017995.117
  doi: 10.1186/1475-2891-12-138
– ident: 2024051615022080000_9.3.e017995.68
  doi: 10.1016/j.clnu.2010.09.009
– ident: 2024051615022080000_9.3.e017995.98
  doi: 10.1017/S0007114517000204
– volume: 7
  start-page: 473
  year: 2016
  ident: 2024051615022080000_9.3.e017995.105
  article-title: Effect of probiotic yoghurt on animal-based diet-induced change in gut microbiota: an open, randomised, parallel-group study
  publication-title: Benef Microbes
  doi: 10.3920/BM2015.0173
– ident: 2024051615022080000_9.3.e017995.130
  doi: 10.2337/dc17-S008
– volume: 23
  start-page: 2364
  year: 2015
  ident: 2024051615022080000_9.3.e017995.109
  article-title: Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults
  publication-title: Obesity
  doi: 10.1002/oby.21230
– ident: 2024051615022080000_9.3.e017995.83
  doi: 10.1111/jdi.12863
– ident: 2024051615022080000_9.3.e017995.133
  doi: 10.1038/nm.4345
– ident: 2024051615022080000_9.3.e017995.13
  doi: 10.1016/j.nutres.2015.05.008
– volume: 33
  start-page: 417
  year: 2014
  ident: 2024051615022080000_9.3.e017995.128
  article-title: Effects of probiotic yogurt on fat distribution and gene expression of proinflammatory factors in peripheral blood mononuclear cells in overweight and obese people with or without weight-loss diet
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2013.874937
– volume: 16
  start-page: e05315
  year: 2018
  ident: 2024051615022080000_9.3.e017995.18
  publication-title: EFSA Journal
– volume: 4
  year: 2015
  ident: 2024051615022080000_9.3.e017995.95
  article-title: Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial
  publication-title: J Nutr Sci
  doi: 10.1017/jns.2015.5
– volume: 37
  start-page: 9
  year: 2018
  ident: 2024051615022080000_9.3.e017995.103
  article-title: Effect of Lactobacillus casei strain Shirota-fermented milk on metabolic abnormalities in obese prediabetic Japanese men: a randomised, double-blind, placebo-controlled trial
  publication-title: Biosci Microbiota Food Health
  doi: 10.12938/bmfh.17-012
– ident: 2024051615022080000_9.3.e017995.114
  doi: 10.3109/09637486.2013.775224
– ident: 2024051615022080000_9.3.e017995.31
  doi: 10.1111/apt.12758
– volume: 35
  start-page: 163
  year: 2016
  ident: 2024051615022080000_9.3.e017995.124
  article-title: Effect of Bifidobacterium animalis ssp. lactis GCL2505 on visceral fat accumulation in healthy Japanese adults: a randomized controlled trial
  publication-title: Biosci Microbiota Food Health
  doi: 10.12938/bmfh.2016-002
– ident: 2024051615022080000_9.3.e017995.136
  doi: 10.1007/s00394-013-0649-9
– ident: 2024051615022080000_9.3.e017995.139
  doi: 10.1017/S0007114508043808
– ident: 2024051615022080000_9.3.e017995.107
  doi: 10.1016/j.jff.2012.09.001
– ident: 2024051615022080000_9.3.e017995.129
  doi: 10.1016/j.jacc.2013.11.004
– volume: 35
  start-page: 506
  year: 2016
  ident: 2024051615022080000_9.3.e017995.40
  article-title: The consumption of synbiotic bread containing lactobacillus sporogenes and inulin affects nitric oxide and malondialdehyde in patients with type 2 diabetes mellitus: randomized, double-blind, placebo-controlled trial
  publication-title: J Am Coll Nutr
  doi: 10.1080/07315724.2015.1032443
– ident: 2024051615022080000_9.3.e017995.20
  doi: 10.1016/0197-2456(86)90046-2
– ident: 2024051615022080000_9.3.e017995.1
  doi: 10.1038/nature12506
– volume: 15
  year: 2015
  ident: 2024051615022080000_9.3.e017995.57
  article-title: Effect of microbial cell preparation on renal profile and liver function among type 2 diabetics: a randomized controlled trial
  publication-title: BMC Complement Altern Med
  doi: 10.1186/s12906-015-0952-5
– ident: 2024051615022080000_9.3.e017995.3
  doi: 10.1126/science.1208344
– volume: 8
  start-page: 256
  year: 2016
  ident: 2024051615022080000_9.3.e017995.29
  article-title: Effect of probiotic supplementation on cognitive function and metabolic status in alzheimer’s disease: a randomized, double-blind and controlled trial
  publication-title: Front Aging Neurosci
  doi: 10.3389/fnagi.2016.00256
– volume: 68
  start-page: 447
  year: 2014
  ident: 2024051615022080000_9.3.e017995.70
  article-title: The effects of probiotic bacteria on glycaemic control in overweight men and women: a randomised controlled trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2013.294
– ident: 2024051615022080000_9.3.e017995.6
  doi: 10.1126/science.aad3503
– volume: 116
  start-page: 1394
  year: 2016
  ident: 2024051615022080000_9.3.e017995.26
  article-title: The effects of synbiotic supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes: a randomised, double-blind, placebo-controlled trial
  publication-title: Br J Nutr
  doi: 10.1017/S0007114516003457
– ident: 2024051615022080000_9.3.e017995.21
  doi: 10.1136/bmj.327.7414.557
– volume: 64
  start-page: 413
  year: 2017
  ident: 2024051615022080000_9.3.e017995.54
  article-title: Effects of probiotics on nonalcoholic fatty liver disease in obese children and adolescents
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0000000000001422
– ident: 2024051615022080000_9.3.e017995.85
  doi: 10.1016/j.clnu.2016.08.015
– ident: 2024051615022080000_9.3.e017995.50
  doi: 10.1016/j.nut.2011.08.013
– volume: 13
  start-page: 705
  year: 2018
  ident: 2024051615022080000_9.3.e017995.75
  article-title: Probiotic supplementation increases obesity with no detectable effects on liver fat or gut microbiota in obese Hispanic adolescents: a 16-week, randomized, placebo-controlled trial
  publication-title: Pediatr Obes
  doi: 10.1111/ijpo.12273
– volume: 32
  start-page: 716
  year: 2016
  ident: 2024051615022080000_9.3.e017995.43
  article-title: Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: a randomized trial. Effects of probiotics on metabolic syndrome
  publication-title: Nutrition
  doi: 10.1016/j.nut.2015.11.001
– volume: 11
  start-page: 74
  issue: Suppl 1
  year: 2015
  ident: 2024051615022080000_9.3.e017995.61
  article-title: The effect of probiotic soy milk and soy milk on anthropometric measures and blood pressure in patients with type II diabetes mellitus: A randomized double-blind clinical trial
  publication-title: ARYA Atheroscler
– volume: 10
  year: 2015
  ident: 2024051615022080000_9.3.e017995.12
  article-title: Effect of probiotics on glycemic control: a systematic review and meta-analysis of randomized, controlled trials
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0132121
– volume: 4
  start-page: 131
  year: 2017
  ident: 2024051615022080000_9.3.e017995.74
  article-title: The potential role of probiotics or/and prebiotic on serum lipid profile and insulin resistance in alcoholic fatty liver disease: A double blind randomized clinical trial
  publication-title: Crescent Journal of Medical and Biological Sciences
– volume: 5
  start-page: 1239
  year: 2014
  ident: 2024051615022080000_9.3.e017995.92
  article-title: The effects of probiotic supplementation on markers of blood lipids, and blood pressure in patients with prediabetes: a randomized clinical trial
  publication-title: Int J Prev Med
– volume: 117
  start-page: 1312
  year: 2017
  ident: 2024051615022080000_9.3.e017995.45
  article-title: Probiotic yogurt and acidified milk similarly reduce postprandial inflammation and both alter the gut microbiota of healthy, young men
  publication-title: Br J Nutr
  doi: 10.1017/S0007114517000885
– ident: 2024051615022080000_9.3.e017995.48
  doi: 10.1186/s41043-015-0034-9
– ident: 2024051615022080000_9.3.e017995.127
  doi: 10.1097/MPG.0b013e31821f9b85
– ident: 2024051615022080000_9.3.e017995.28
  doi: 10.1080/07315724.2005.10719473
– ident: 2024051615022080000_9.3.e017995.119
  doi: 10.1038/ijo.2017.210
– ident: 2024051615022080000_9.3.e017995.79
  doi: 10.1017/S0007114513001037
– volume: 70
  start-page: 582
  year: 2016
  ident: 2024051615022080000_9.3.e017995.63
  article-title: Antiobesity effect of Pediococcus pentosaceus LP28 on overweight subjects: a randomized, double-blind, placebo-controlled clinical trial
  publication-title: Eur J Clin Nutr
  doi: 10.1038/ejcn.2016.17
– ident: 2024051615022080000_9.3.e017995.4
  doi: 10.1038/nature12480
– ident: 2024051615022080000_9.3.e017995.38
  doi: 10.5812/ircmj.42902
– ident: 2024051615022080000_9.3.e017995.34
  doi: 10.1016/j.clnu.2013.05.015
– ident: 2024051615022080000_9.3.e017995.44
  doi: 10.1017/S0007114515001786
– ident: 2024051615022080000_9.3.e017995.24
  doi: 10.2307/2669529
– ident: 2024051615022080000_9.3.e017995.87
  doi: 10.1016/j.clnu.2013.12.006
– ident: 2024051615022080000_9.3.e017995.69
  doi: 10.1038/sj.ejcn.1601555
– volume: 76
  start-page: 1249
  year: 2002
  ident: 2024051615022080000_9.3.e017995.104
  article-title: Effect of Lactobacillus plantarum 299v on cardiovascular disease risk factors in smokers
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/76.6.1249
– ident: 2024051615022080000_9.3.e017995.58
  doi: 10.1097/MPG.0b013e318263066c
– ident: 2024051615022080000_9.3.e017995.47
  doi: 10.1038/sj.ejcn.1600722
– ident: 2024051615022080000_9.3.e017995.14
  doi: 10.1017/S0007114516000076
– volume: 8
  start-page: 250
  year: 2017
  ident: 2024051615022080000_9.3.e017995.84
  article-title: Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals
  publication-title: Food Funct
  doi: 10.1039/C6FO00993J
SSID ssj0000459552
Score 2.579332
SecondaryResourceType review_article
Snippet ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver...
To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease....
To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver...
OBJECTIVE: To systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty...
SourceID pubmedcentral
hal
proquest
pubmed
crossref
bmj
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage e017995
SubjectTerms Clinical trials
Diabetes
Diabetes Mellitus - metabolism
Diabetes Mellitus - therapy
Dietary Supplements
Endocrinology and metabolism
Evidence-based medicine
Fatty liver
Food and Nutrition
Human health and pathology
Humans
Insulin resistance
Life Sciences
Liver diseases
Meta-analysis
Non-alcoholic Fatty Liver Disease - metabolism
Non-alcoholic Fatty Liver Disease - therapy
Nutrition and Metabolism
Obesity
Obesity - metabolism
Obesity - therapy
Probiotics
Probiotics - pharmacology
Randomized Controlled Trials as Topic
Santé publique et épidémiologie
Systematic review
Treatment Outcome
SummonAdditionalLinks – databaseName: Health & Medical Collection
  dbid: 7X7
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1bb9MwFLbYkBAviDuFgQxC4mXRYiexW17QhJgKYjwxqW-RHdvaUJcUmk3ib_EL-Y7jZhSkiZeqTezY9Tnxufo7jL2GzGkgCnxmsNdlZWlUZowK-ClCHgiPxJG_4_iLmp-UnxbVIjnc1imtcrMnxo3adQ35yA-kjFFSmZfvVt8zqhpF0dVUQmOH3RTQRKh0g17o0ccCdWVWVTKBDYlCHdjzb1SVCrwhKOOS0NAgVHB1SyztnFJS5L8a59-Jk39IoqO77E5SIfnhQPN77IZv77NbxylI_oD9-hhPPvIucDtgMaP1KuItESYz71reDeUA9vnG9cpN63jbtZkZSuaeNTyYvv_Jl5S3wVMYh8eTL97xS1jYdOZq_ZYbfgUGzYeDMPFh5743mUmQJzQXCEXXgavQPeXHL_E1Vg1ZP2QnRx--vp9nqTRDZqtc9fjUjZc6NBXUXicD3mQhQGOtp177cmanXhXQNpykLOdppazwQhewzqzzogzFI7aLP-WfMI6nBOPyUmubl75S0F9gHFtrK4XmTkzYG9CnXg3gG3U0WgpVJ0rWRMl6oOSEyQ0N6yYhnFOhjeX1nfbHTv81xiswx9iSwLnnh59rugZtiWLU8hJT3tvwTp22hHV9xcAT9nK8jWWnCI1pfXcR2wgtsFAY5_HAauNQRT6DcSymE6a3mHBrLtt32rPTCBiuSo0lFU-vn9YzdhvDz-KBy3yP7fY_LvxzaFy9fRFfq99bUC0V
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Journals: Open Access
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwELbaIiEuCCiPhYIMQuLSQJw49i4SQhWi2qKWEyv1ZtmJoxZtk9JNK_q3-IV84zhblpfgstrEz3jGmZl45hvGnkPmlBAFPrF41yVSWpVYq2pcijqtCY-kou8dBx_VdCY_HBaHa2zIihoXcPFb047ySc3O5i-_frl8iw3_JmYkeeVOPlMRCC7IjZIgztbZtXBgRL58Ud8Pr2ZZTIqQhSdLpUygyhcRiegP_UDi4O6KzFo_Io_JX9XRn70qfxBTu7fYzahf8p2eIW6zNd_cYdcP4gn6Jvu2F8IieVtz1wM1o_ZpAGMiwGbeNrztcwVs8-G7LLdNxZu2SWyfT_e45LXtuks-J6cOHs94eAiL8RW_gPlNAVmL19zyK6Ro3kfJhM5OfGcTG_FQaC6QmFULlkPz6Dw_x9-QUmRxl8123396N01i3obEFanq8KtLn-m6LKATV1mNbS4EGEDrsddeTtzYqxyqSJWRC_S4UE54oXOYbq7yQtb5PbaBh_IPGEcvta1SqbVLpS8UlBtYzs65QqF6JUbsBehjTntkDhMsmlyZSElDlDQ9JUcsG2hoygh_Tlk45n9vtL1s9E9jPANzLGsScvd0Z9_QPahSdICdXWDKWwPvmIHdTZYFHwBw5Yg9XRZj2en4xja-PQ91hBZYKIxzv2e15VB5OoHlLMYjpleYcGUuqyXN8VFAE1dSY0nFw_971EfsBq4mIToz3WIb3dm5fwz1rHNPwpb7DkhiOOI
  priority: 102
  providerName: Scholars Portal
Title Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials
URI https://bmjopen.bmj.com/content/9/3/e017995.full
https://www.ncbi.nlm.nih.gov/pubmed/30928918
https://www.proquest.com/docview/2200127204
https://www.proquest.com/docview/2201711735
https://hal.sorbonne-universite.fr/hal-02165922
https://pubmed.ncbi.nlm.nih.gov/PMC6475231
Volume 9
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELfoJiFeJr7pGJVBSLwsIk4cO91bN20URCaENlSeIjtxtKEumWg2iX-Lv5CfHTcsINBekibxV32X3Nl39ztCXkPmFBAFJlD41gWcKxEoJSpcsiqsLB5Jafc7smMxP-UfFsniRrD60ILPYvFWX3yziaRATmadJC2A2YhsRhIrBcvQX0_6LRVoJ9PE5diJQs4DKOqJxxn6RzuQJ7g7kEijM-sP-bey-afP5A0hdHSfbHntkc46cj8gd0z9kNzNvH38Efn53gU90qaiuoNhRulLB7Vk4ZhpU9OmywSwS9e7rlTVJa2bOlBdttzzglaqbX_QpXXZoN6CQ13QiynpNRbXNtxqtUcV_Y0DTbsYGNfYhWlVoDzaiR0L5GHZgKFQ3bvGL_HTJQxZPSanR4cnB_PAZ2UIdBKKFkdZmEhWRQKNt4wqvMSMgbxSpkYaPtWpETEUjTKyDs5pIjQzTMZYmOnSMF7FT8gG_pR5RihaqVQZcil1yE0ioLpgXay1TgSKl2xM3oA--WWHu5G79Uosck_J3FIy7yg5JtGahnnhwc1tjo3l_yvt9pVu1ccrMEdf0uJyz2cfc3sPipI1T0fXGPLOmndy_zVY5VHkLPzgyjF52T_GtFvjjKpNc-XKMMkwUejnacdqfVdxOAW3s3RM5IAJB2MZPqnPzxxWuOASU8q2bz2Tz8k9XE1d2GW4Qzba71fmBfSuVk_ISC7kxL1zE7I5O8iyLzjvHx5_-jxxexk4vlswHDOe_gIKlS_5
linkProvider BMJ Publishing Group Ltd
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1fb9MwELe2TgJeEP8pDDAIxMuixU5it0gTGrCpZW2F0Cbtzdixow11SaHZ0L4WH4DPxp3jdBSkiZe9VG3iP1ff2Xe2735HyEvQOTmoAhdpWOuiNNUi0loU8JMVcYF4JBbPO8YTMThIPx5mhyvkVxsLg26V7ZroF2pb5XhGvsm5vyXlcfp29i3CrFF4u9qm0NAhtYLd8hBjIbBjz53_gC3cfGv4Afj9ivPdnf33gyhkGYhMFosaPmXuuCzyDCw4ywsQSsaAXCl7Trq0b3pOJKA4LUeH3V4mDHNMJrDRMNaxtEig3VWyluIBSoesvduZfPq8OOUBg6mfZTzAHbFEbJqTr5gXC6SToc8n4rGBWoOnS4px9QjdMv-1ef923fxDF-7eIjeDEUu3G6m7TVZceYdcG4dr-rvk59DHXtKqoKZBg4bSM4_4hKjQtCpp1SQk2KDt4S_VpaVlVUa6Sdp7nNNC1_U5naLnCA0XSdTH3jhLz2CPj1Ff8zdU0ws4atqE4vjGTlytIx1AV5AWUMu2ArmG6sFDfwpffd6S-T1ycCVsu0868KfcQ0KhlULbOJXSxKnLBFhQsD03xmQCilvWJa-BP2rWwH8ov21KhAqcVMhJ1XCyS3jLQ5UHjHVM9TG9vNLGotJ_9fEChGNREuHBB9sjhc_AXsNbcn4GJK-3sqPCojRXF1OoS54vXsOw4x2RLl116sswyWCgoJ8HjagtukriPmzPWa9L5JIQLtGy_KY8PvKQ5SKVMKTs0eVkPSPXB_vjkRoNJ3uPyQ0gpe_DP-N10qm_n7onYP_V5mmYZJR8uep5_Rv9ym9h
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtR1db9Mw0NqGNPGC-F7HAINAvCxq7Dh2i4TQxKha9iEemNS3YCe2NtQlHc2G9rd45Ndx5zgZBWniZS9Vm_jj6jv77nxfhLwCnpMDK7CRhrMuEkLLSGvp4CdzscN8JAXedxwcyvGR-DRNpyvkVxsLg26V7ZnoD-qiyvGOvM-5t5LyWPRdcIv4vDt6Pz-LsIIUWlrbchoNiezZyx-gvi3eTXYB1685H3388mEchQoDkUljWcOnyi1XLk9Beiu4A4JkDEBVamCVFUMzsDIBpllwdNYdpNIwy1QCSoYpLBMugXFXyS2VCIFlI9RUdfc7ICoN05SHREcskX1z-g0rYgFdMvT2xExswNDg6RJLXD1Gh8x_pd2_nTb_4IKju-ROEF_pTkNv98iKLe-T9YNgoH9Afk581CWtHDVNHmhoPfe5njAfNK1KWjWlCLZpe-1LdVnQsioj3ZTrPcmp03V9SWfoM0KDCYn6qBtb0AvQ7jHea_GWanqViJo2QTh-sFNb60iHdCsICzDkogKKhu7BN38GX33FksVDcnQjSHtE1uBP2Q1CYRSni1goZWJhUwmyEyjmxphUQvOC9cgbwE82bxJ_ZF5hSmQWMJkhJrMGkz3CWxxmeciujkU-Ztd32u46_dccL4E4upaYGHy8s5_hM5DU0D7OLwDkrZZ2snAcLbKrzdMjL7rXsOxoHdKlrc59G6YYLBTM87ghtW6qJB6CYs4GPaKWiHAJluU35cmxT1YuhYIlZZvXg_WcrMNuzvYnh3tPyG2AZOjjPuMtslZ_P7dPQfCrzTO_wyj5etNb-jf_nWz9
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Impact+of+bacterial+probiotics+on+obesity%2C+diabetes+and+non-alcoholic+fatty+liver+disease+related+variables%3A+a+systematic+review+and+meta-analysis+of+randomised+controlled+trials&rft.jtitle=BMJ+open&rft.au=Koutnikova%2C+Hana&rft.au=Genser%2C+Bernd&rft.au=Monteiro-Sepulveda%2C+Milena&rft.au=Faurie%2C+Jean-Michel&rft.date=2019-03-30&rft.issn=2044-6055&rft.eissn=2044-6055&rft.volume=9&rft.issue=3&rft.spage=e017995&rft_id=info:doi/10.1136%2Fbmjopen-2017-017995&rft.externalDBID=n%2Fa&rft.externalDocID=10_1136_bmjopen_2017_017995
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2044-6055&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2044-6055&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2044-6055&client=summon