Resistance to leptin-replacement therapy in Berardinelli–Seip congenital lipodystrophy: an immunological origin - Beltrand, Jacques; Lahlou, Najiba; Le Charpentier, Tifenn; Sebag, Guy; Leka, Sofia; Polak, Michel; Tubiana-Rufi, Nadia; Lacombe, Didier; de Kerdanet, Marc; Huet, Frederic; Robert, Jean-Jacques; Chevenne, Didier; et al. (European journal of endocrinology, 2010)
Keywords: Adolescent; Antibodies, Neutralizing - immunology; Antibodies, Neutralizing - metabolism; Associated diseases and complications; Biological and medical sciences; Blood Glucose - metabolism; Body Composition; Child; Child, Preschool; Clinical Study; Diabetes. Impaired glucose tolerance; Drug Administration Schedule; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Female; Fundamental and applied biological sciences. Psychology; Humans; Leptin - administration & dosage; Leptin - metabolism; Lipid Metabolism; Lipids - blood; Lipodystrophy, Congenital Generalized - immunology; Lipodystrophy, Congenital Generalized - metabolism; Lipodystrophy, Congenital Generalized - therapy; Liver - metabolism; Male; Medical sciences; Patient Selection; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; Vertebrates: endocrinology; Endocrinopathy; Resistance; Skin disease; Replacement therapy; Berardinelli lipodystrophy; Congenital; Leptin; Adipose tissue disorders; Adipokine; Congenital disease; Endocrinology; Genetic disease