How much of invasive clinical research is still ethically justified?
[...]the presently discussed studies, similar to previous reports from China in which LP were used in glaucoma and ocular hypertension patients, raise a general ethical concern and question: how much invasive procedure could we propose to the patient in clinical research settings (with no therapeuti...
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| Published in | British journal of ophthalmology Vol. 96; no. 8; pp. 1145 - 1146 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
BMA House, Tavistock Square, London, WC1H 9JR
BMJ Publishing Group Ltd
01.08.2012
BMJ Publishing Group LTD |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0007-1161 1468-2079 1468-2079 |
| DOI | 10.1136/bjophthalmol-2012-301832 |
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| Abstract | [...]the presently discussed studies, similar to previous reports from China in which LP were used in glaucoma and ocular hypertension patients, raise a general ethical concern and question: how much invasive procedure could we propose to the patient in clinical research settings (with no therapeutic context of the procedure as it was in both cases)? |
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| AbstractList | [...]the presently discussed studies, similar to previous reports from China in which LP were used in glaucoma and ocular hypertension patients, raise a general ethical concern and question: how much invasive procedure could we propose to the patient in clinical research settings (with no therapeutic context of the procedure as it was in both cases)? |
| Author | Grzybowski, Andrzej |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22535329$$D View this record in MEDLINE/PubMed |
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| Copyright | 2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. Copyright: 2012 (c) 2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. |
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| DOI | 10.1136/bjophthalmol-2012-301832 |
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| References | Killer, Miller, Flammer 2012; 96 Grzybowski, Sade, Loff 2011; 118 Jaggi, Miller, Flammer 2012; 96 Grzybowski 2012; 90 Hayreh 2009; 247 Pasquale 2008; 115 21398413 - Br J Ophthalmol. 2012 Jan;96(1):53-6 22116958 - Br J Ophthalmol. 2012 Apr;96(4):544-8 |
| References_xml | – volume: 247 start-page: 721 year: 2009 article-title: Cerebrospinal fluid pressure and glaucomatous optic disc cupping publication-title: Graefes Arch Clin Exp Ophthalmol – volume: 90 start-page: e77 year: 2012 article-title: Unjustified invasive clinical research raises ethical concerns publication-title: Acta Ophthalmol – volume: 96 start-page: 53 year: 2012 article-title: Original article: optic nerve sheath diameter in normal-tension glaucoma patients publication-title: Br J Ophthalmol – volume: 118 start-page: 787 year: 2011 article-title: Ethical problems in invasive clinical research publication-title: Ophthalmology – volume: 96 start-page: 544 year: 2012 article-title: Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma publication-title: Br J Ophthalmol – volume: 115 start-page: 761 year: 2008 article-title: Low intracranial pressure: a tipping point in our understanding of primary open-angle glaucoma? publication-title: Ophthalmology – reference: 22116958 - Br J Ophthalmol. 2012 Apr;96(4):544-8 – reference: 21398413 - Br J Ophthalmol. 2012 Jan;96(1):53-6 |
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| SubjectTerms | Cerebrospinal Fluid - physiology Electrophysiology Ethics Female glaucoma Human subjects Humans Informed consent Low Tension Glaucoma - diagnostic imaging Low Tension Glaucoma - physiopathology Male medical education Myelin Sheath - diagnostic imaging Optic Disk - diagnostic imaging optic nerve Optic Nerve - diagnostic imaging Optic Nerve - physiopathology Patients retina Studies Tomography, X-Ray Computed - methods |
| Title | How much of invasive clinical research is still ethically justified? |
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