Regulatory T cells and IFN-γ-producing Th1 cells play a critical role in the pathogenesis of Sjögren's Syndrome - Wang, Yin-Hu; Li, Wenyi; McDermott, Maxwell; Son, Ga-Yeon; Maiti, George; Zhou, Fang; Tao, Anthony; Raphael, Dimitrius; Moreira, Andre L; Shen, Boheng; Vaeth, Martin; Nadorp, Bettina; et al. (bioRxiv, 2024)
Keywords: Adoptive transfer; Autoantibodies; Calcium signalling; CD4 antigen; Clonal deletion; Effector cells; Flow cytometry; Immunological memory; Immunology; Immunoregulation; Inflammation; Lacrimal gland and Nasolacrimal duct; Leukocytes (mononuclear); Lymphocytes; Lymphocytes B; Lymphocytes T; Lymphoid tissue; Lymphopenia; Memory cells; Pathogenesis; Pathogenicity; Peripheral blood mononuclear cells; Salivary gland; Sjogren's syndrome; STIM1 protein; Transcriptomics; γ-Interferon; Th1 cells; interferon gamma; Calcium; STIM1; Sjogren’s Disease; STIM2; SOCE; Treg cells; Sjogren’s syndrome; Foxp3; Ca; single cell RNA-Seq