TMPRSS2-ERG confers resistance to antiandrogens: mechanism and therapeutic implications - Sekar, Arunachalam; Chatterjee, Rishita; Selvadurai, Boobash Raj; Pal, Lipika R; Verma, Aakanksha; Nataraj, Nishanth Belugali; Garcia, Diana Drago; Giri, Suvendu; Genna, Alessandro; Karatekin, Feride; Gupta, Nitin; Zerbib, Mirie; et al. (bioRxiv, 2025)
Keywords: Allosteric properties; Androgen receptors; Antiandrogens; Biopsy; Cancer Biology; Chemotherapy; Clinical trials; Epigenetics; Funding; Glucocorticoid receptors; Hydrocortisone; Pharmaceuticals; Prostate cancer; R&D; Research & development; Stockholders; ETS family; TMPRSS2 fusions; prostate cancer; corticosteroids; GR antagonists