AB1446 ASSOCIATION OF GENETICALLY PROXIED JANUS KINASE INHIBITOR TARGETS WITH CARDIOVASCULAR RISK: A DRUG-TARGET MENDELIAN RANDOMIZATION STUDY - Dai, L.; Song, Q. Y.; Zou, Y. W.; Su, Y.; Su, L. W.; MA, J. D.; Pan, J.; Ouyang, Z. M.; Lu, Y.; Wu, T.; Lin, J. Z.; Jia, P. W.; et al. (Annals of the rheumatic diseases, 2024)
Keywords: Blood levels; Cardiovascular disease; Cardiovascular diseases; Coronary artery disease; Enzyme inhibitors; Epidemiology; Gene expression; Genetics; Genome-wide association studies; Health risk assessment; Heart diseases; Janus kinase; Janus kinase 2; Kinases; Pleiotropy; Quantitative trait loci; Rheumatoid arthritis; Safety; Scientific Abstracts; Sensitivity analysis; Single-nucleotide polymorphism; Stroke; Targeted synthetic drugs; Therapeutic targets; Tyk2 protein; Genetics; Safety; Targeted synthetic drugs; Cardiovascular diseases; Epidemiology