Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever - Kohl, Lisa; Alam Siddique, Nur A; Bodendorfer, Barbara; Berger, Raffaela; Preikschat, Annica; Daniel, Christoph; Oelke, Martha; Mauermeir, Michael; Kai-Ting, Yang; Hayek, Inaya; Szperlinski, Mauela; Schulze-Luehrmann, Jan; et al. (bioRxiv, 2022)
Keywords: Aconitate decarboxylase; Chronic infection; Gene expression; Germfree; Immunology; Infections; Inflammation; Macrophages; Pathogens; Q fever; Replication; Trachea; itaconate; Q fever; immunometabolism; Immune responsive gene 1 (Irg1); Cis-aconitate decarboxylase 1 (Acod1)