Lipo-Chitooligosaccharides Induce Specialized Fungal Metabolite Profiles That Modulate Bacterial Growth
The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharid...
Saved in:
| Published in | mSystems Vol. 7; no. 6; pp. e0105222 - 22 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Society for Microbiology
01.12.2022
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 2379-5077 2379-5077 |
| DOI | 10.1128/msystems.01052-22 |
Cover
| Abstract | The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities.
Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen
Aspergillus fumigatus
to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to
A. fumigatus
resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition.
IMPORTANCE
The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. |
|---|---|
| AbstractList | Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. IMPORTANCE The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals.Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. IMPORTANCE The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. IMPORTANCE The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. ABSTRACT Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. IMPORTANCE The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial rhizobia or mycorrhizal fungi. Recent studies showing that LCOs are widespread across the fungal kingdom have raised questions about the ecological function of these compounds in organisms that do not form symbiotic relationships with plants. To elucidate the ecological function of these compounds, we investigate the metabolomic response of the ubiquitous human pathogen Aspergillus fumigatus to LCOs. Our metabolomics data revealed that exogenous application of various types of LCOs to A. fumigatus resulted in significant shifts in the fungal metabolic profile, with marked changes in the production of specialized metabolites known to mediate ecological interactions. Using network analyses, we identify specific types of LCOs with the most significant effect on the abundance of known metabolites. Extracts of several LCO-induced metabolic profiles significantly impact the growth rates of diverse bacterial species. These findings suggest that LCOs may play an important role in the competitive dynamics of non-plant-symbiotic fungi and bacteria. This study identifies specific metabolomic profiles induced by these ubiquitously produced chemicals and creates a foundation for future studies into the potential roles of LCOs as modulators of interkingdom competition. IMPORTANCE The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual motion in natural product discoveries. Here, we demonstrated that one of the best-studied symbiosis signaling compounds, lipo-chitooligosaccharides (LCOs), play a role in activating some of these BGCs, resulting in the production of known, putative, and unknown metabolites with biological activities. This collection of metabolites induced by LCOs differentially modulate bacterial growth, while the LCO standards do not convey the same effect. These findings create a paradigm shift showing that LCOs have a more prominent role outside of host recognition of symbiotic microbes. Importantly, our work demonstrates that fungi use LCOs to produce a variety of metabolites with biological activity, which can be a potential source of bio-stimulants, pesticides, or pharmaceuticals. |
| Author | Ané, Jean-Michel Carrell, Alyssa A. Abraham, Paul E. Pelletier, Dale A. Rush, Tomás A. Giannone, Richard J. Drott, Milton T. Fort, Sébastien Lane, Matthew J. Golan, Jacob J. Cottaz, Sylvain Tannous, Joanna Jacobson, Daniel A. Kainer, David Labbé, Jesse L. Gopalakrishnan Meena, Muralikrishnan Keller, Nancy P. |
| Author_xml | – sequence: 1 givenname: Tomás A. orcidid: 0000-0002-3207-1466 surname: Rush fullname: Rush, Tomás A. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 2 givenname: Joanna surname: Tannous fullname: Tannous, Joanna organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 3 givenname: Matthew J. surname: Lane fullname: Lane, Matthew J. organization: Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, Tennessee, USA – sequence: 4 givenname: Muralikrishnan surname: Gopalakrishnan Meena fullname: Gopalakrishnan Meena, Muralikrishnan organization: National Center for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 5 givenname: Alyssa A. surname: Carrell fullname: Carrell, Alyssa A. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 6 givenname: Jacob J. surname: Golan fullname: Golan, Jacob J. organization: Department of Botany, University of Wisconsin-Madison, Madison, Wisconsin, USA, Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA – sequence: 7 givenname: Milton T. surname: Drott fullname: Drott, Milton T. organization: Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA, USDA-ARS Cereal Disease Laboratory, St. Paul, Minnesota, USA – sequence: 8 givenname: Sylvain surname: Cottaz fullname: Cottaz, Sylvain organization: Université Grenoble Alpes, CNRS, CERMAV, Grenoble, France – sequence: 9 givenname: Sébastien surname: Fort fullname: Fort, Sébastien organization: Université Grenoble Alpes, CNRS, CERMAV, Grenoble, France – sequence: 10 givenname: Jean-Michel surname: Ané fullname: Ané, Jean-Michel organization: Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA, Department of Agronomy, University of Wisconsin-Madison, Madison, Wisconsin, USA – sequence: 11 givenname: Nancy P. orcidid: 0000-0002-4386-9473 surname: Keller fullname: Keller, Nancy P. organization: Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA, Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA – sequence: 12 givenname: Dale A. orcidid: 0000-0002-4321-7918 surname: Pelletier fullname: Pelletier, Dale A. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 13 givenname: Daniel A. surname: Jacobson fullname: Jacobson, Daniel A. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 14 givenname: David surname: Kainer fullname: Kainer, David organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 15 givenname: Paul E. surname: Abraham fullname: Abraham, Paul E. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 16 givenname: Richard J. surname: Giannone fullname: Giannone, Richard J. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA – sequence: 17 givenname: Jesse L. surname: Labbé fullname: Labbé, Jesse L. organization: Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36453934$$D View this record in MEDLINE/PubMed https://hal.science/hal-03989151$$DView record in HAL https://www.osti.gov/servlets/purl/1902813$$D View this record in Osti.gov |
| BookMark | eNp9ksFu1DAQhiNUREvpA3BBESc4ZLGdxI4vSGVF25W2Aolytia2s_HKiRfbKSpPj7dpq7aHnmxNvvk0_jNvs4PRjTrL3mO0wJg0X4ZwE6IewgJhVJOCkFfZESkZL2rE2MGj-2F2EsIWIYRpyTDhb7LDklZ1ycvqKNuszc4Vy95E56zZuABS9uCN0iFfjWqSOv-109KANf-0ys-mcQM2v9QR2sRHnf_0rjM20Vc9xPzSqclCKn8DGbVPbfm5d39j_y573YEN-uTuPM5-n32_Wl4U6x_nq-XpuoCa1rHgklaQZlSUNDVSNWqUxJ3SCJFOlTVrFepKYAizjrKmxWWrWip5A3VTg4aqPM5Ws1c52IqdNwP4G-HAiNuC8xsBPhpptWgYpRq3rUSEV4xDi2iLNCUlbhBXBCXX19m1m9pBK6nH6ME-kT79MppebNy14IxWvMFJ8HEWuBCNCDLlJXvpxlHLKDBHJDEJ-jxD_TP3xela7Guo5A3HNb7eCz_dTeTdn0mHKAYTpLYWRu2mIAirKsrSP98HsZhRCAMRWzf5MeUuMBL77RH32yNut0cQkho-PH7twyj3u5IAPAPSuxC87h6Ql6TsWU8KAaJx-8CMfaHzP6tF5-U |
| CitedBy_id | crossref_primary_10_3389_fmicb_2023_1296916 crossref_primary_10_1016_j_bidere_2025_100007 crossref_primary_10_1016_j_cub_2024_03_015 crossref_primary_10_1093_pnasnexus_pgad322 crossref_primary_10_1038_s41564_024_01727_5 crossref_primary_10_1007_s40009_023_01320_0 |
| Cites_doi | 10.1080/14786419.2012.750316 10.1128/MMBR.66.3.447-459.2002 10.1111/j.1570-7458.1988.tb02283.x 10.1002/0471250953.bi1411s37 10.1098/rstb.2016.0023 10.3389/fmicb.2015.00299 10.1146/annurev.bi.65.070196.002443 10.1101/2022.08.11.503656 10.1093/bioinformatics/btq054 10.1128/AEM.64.10.3707-3712.1998 10.1038/ja.2016.155 10.1038/344781a0 10.1371/journal.pone.0112635 10.1186/1471-2105-7-123 10.4148/1941-4765.1175 10.1093/glycob/12.6.79r 10.1111/nph.12898 10.3389/ffunb.2021.716511 10.1007/BF02256576 10.1038/nchembio.2061 10.3389/ffunb.2022.808578 10.1016/j.csbj.2021.03.034 10.1080/13693780600835773 10.1002/ccr3.2516 10.1021/jo00252a008 10.1002/ajb2.1373 10.1111/j.1550-7408.1980.tb04681.x 10.1038/s41573-020-00114-z 10.1016/j.ibiod.2020.105133 10.1099/00221287-13-1-39 10.1016/S0031-9422(96)00650-4 10.3389/fsufs.2020.619676 10.3390/toxins13020085 10.4103/0250-474X.49087 10.1128/CMR.12.1.80 10.1016/0031-9422(73)85148-9 10.3390/molecules23081976 10.1128/EC.3.2.527-535.2004 10.1093/jxb/erh261 10.1128/mSystems.01306-20 10.3389/fmicb.2018.01205 10.1146/annurev-micro-051921-114809 10.1039/c9md00054b 10.1371/journal.ppat.1003289 10.1111/j.1365-313X.2005.02522.x 10.1038/nature09622 10.1105/tpc.18.00676 10.1038/nrmicro.2017.90 10.1038/s41579-018-0121-1 10.1080/13693780802307720 10.1155/2022/9600079 10.1016/S0169-7552(98)00110-X 10.1186/s12859-016-1016-7 10.1016/j.cub.2019.11.038 10.1073/pnas.1809349115 10.1074/mcp.RA120.002059 10.1038/s41467-020-17615-5 10.7164/antibiotics.32.1239 10.1534/g3.116.033084 10.1021/ac300698c 10.1016/S1369-5274(00)00124-7 10.1371/journal.ppat.1005522 10.1080/14786410801972813 10.1128/mBio.01246-17 10.1094/PHP-10-17-0058-RS 10.1371/journal.ppat.1007606 10.1111/nph.12146 10.1128/AEM.71.6.3106-3111.2005 10.1111/nph.15574 10.1073/pnas.1313258110 10.1371/journal.pone.0177050 |
| ContentType | Journal Article |
| Copyright | Distributed under a Creative Commons Attribution 4.0 International License |
| Copyright_xml | – notice: Distributed under a Creative Commons Attribution 4.0 International License |
| CorporateAuthor | Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States) |
| CorporateAuthor_xml | – name: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States) |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 1XC VOOES OIOZB OTOTI 5PM DOA |
| DOI | 10.1128/msystems.01052-22 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Hyper Article en Ligne (HAL) Hyper Article en Ligne (HAL) (Open Access) OSTI.GOV - Hybrid OSTI.GOV PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE CrossRef |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Open Access Full Text url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 2379-5077 |
| Editor | Anderton, Christopher R. |
| Editor_xml | – sequence: 1 givenname: Christopher R. surname: Anderton fullname: Anderton, Christopher R. |
| EndPage | 22 |
| ExternalDocumentID | oai_doaj_org_article_8766e1bbc029479ab06b0e6231809d20 PMC9764981 1902813 oai_HAL_hal_03989151v1 01052-22 36453934 10_1128_msystems_01052_22 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Research Support, Non-U.S. Gov't Journal Article |
| GrantInformation_xml | – fundername: U.S. Department of Energy (DOE) grantid: DE-AC05-00OR22725 funderid: https://doi.org/10.13039/100000015 – fundername: ; grantid: DE-AC05-00OR22725 |
| GroupedDBID | 0R~ 53G 5VS 7X7 8FE 8FH 8FI 8FJ AAFWJ AAGFI AAUOK AAYXX ABUWG ACPRK ADBBV AFKRA AFPKN AHMBA ALMA_UNASSIGNED_HOLDINGS AOIJS BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI CCPQU CITATION EBS FRP FYUFA GROUPED_DOAJ H13 HCIFZ HMCUK HYE KQ8 LK8 M48 M7P M~E O9- OK1 PHGZM PHGZT PIMPY PQGLB PQQKQ PROAC PUEGO RHI RPM RSF UKHRP ALIPV CGR CUY CVF ECM EIF NPM 3V. BBAFP PQEST PQUKI 7X8 1XC ADRAZ EJD VOOES OIOZB OTOTI 5PM |
| ID | FETCH-LOGICAL-a565t-9c64a129d62850d508dc1fde002fd357bd0f3a7017f678b13bdb6c98a585aea43 |
| IEDL.DBID | DOA |
| ISSN | 2379-5077 |
| IngestDate | Wed Aug 27 01:12:32 EDT 2025 Tue Sep 30 17:17:39 EDT 2025 Fri May 19 00:39:39 EDT 2023 Sun Sep 28 07:53:34 EDT 2025 Fri Sep 05 01:24:46 EDT 2025 Wed Dec 21 06:14:39 EST 2022 Thu Apr 03 07:08:44 EDT 2025 Wed Oct 01 03:39:12 EDT 2025 Thu Apr 24 23:10:13 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | biosynthetic gene clusters Aspergillus secondary metabolites bacteria network analyses synergism lipo-chitooligosaccharides |
| Language | English |
| License | This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-a565t-9c64a129d62850d508dc1fde002fd357bd0f3a7017f678b13bdb6c98a585aea43 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 AC05-00OR22725; ANR-17-EURE-0003; ANR-15-IDEX-02; CARN-025-01 USDOE Office of Science (SC), Biological and Environmental Research (BER) French National Research Agency (ANR) Tomás A. Rush and Joanna Tannous contributed equally. The order of co-author names was decided based on alphabetical order. The authors declare no conflict of interest. Present address: Jesse L. Labbé, Invaio Sciences, Cambridge, Massachusetts, USA. |
| ORCID | 0000-0002-4386-9473 0000-0002-3207-1466 0000-0002-4321-7918 0000-0001-8674-0162 0000-0002-6133-9900 0000000232071466 0000000243869473 0000000243217918 |
| OpenAccessLink | https://doaj.org/article/8766e1bbc029479ab06b0e6231809d20 |
| PMID | 36453934 |
| PQID | 2744670774 |
| PQPubID | 23479 |
| PageCount | 21 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_8766e1bbc029479ab06b0e6231809d20 pubmedcentral_primary_oai_pubmedcentral_nih_gov_9764981 osti_scitechconnect_1902813 hal_primary_oai_HAL_hal_03989151v1 proquest_miscellaneous_2744670774 asm2_journals_10_1128_msystems_01052_22 pubmed_primary_36453934 crossref_primary_10_1128_msystems_01052_22 crossref_citationtrail_10_1128_msystems_01052_22 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2022-12-01 |
| PublicationDateYYYYMMDD | 2022-12-01 |
| PublicationDate_xml | – month: 12 year: 2022 text: 2022-12-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: 1752 N St., N.W., Washington, DC |
| PublicationTitle | mSystems |
| PublicationTitleAbbrev | mSystems |
| PublicationTitleAlternate | mSystems |
| PublicationYear | 2022 |
| Publisher | American Society for Microbiology |
| Publisher_xml | – name: American Society for Microbiology |
| References | e_1_3_2_26_2 e_1_3_2_49_2 e_1_3_2_28_2 e_1_3_2_41_2 e_1_3_2_64_2 e_1_3_2_20_2 e_1_3_2_43_2 e_1_3_2_62_2 e_1_3_2_22_2 e_1_3_2_45_2 e_1_3_2_68_2 e_1_3_2_24_2 e_1_3_2_47_2 e_1_3_2_66_2 e_1_3_2_60_2 e_1_3_2_9_2 e_1_3_2_16_2 e_1_3_2_37_2 e_1_3_2_7_2 e_1_3_2_18_2 e_1_3_2_39_2 R Core Team (e_1_3_2_73_2) 2020 e_1_3_2_54_2 e_1_3_2_75_2 e_1_3_2_10_2 e_1_3_2_31_2 e_1_3_2_52_2 e_1_3_2_5_2 e_1_3_2_12_2 e_1_3_2_33_2 e_1_3_2_58_2 e_1_3_2_3_2 e_1_3_2_14_2 e_1_3_2_35_2 Mehedi MAU (e_1_3_2_50_2) 2010; 22 e_1_3_2_56_2 Kosalec I (e_1_3_2_25_2) 2005; 3 e_1_3_2_71_2 e_1_3_2_27_2 e_1_3_2_48_2 e_1_3_2_29_2 e_1_3_2_40_2 e_1_3_2_65_2 e_1_3_2_21_2 e_1_3_2_42_2 e_1_3_2_63_2 e_1_3_2_23_2 e_1_3_2_44_2 e_1_3_2_69_2 e_1_3_2_46_2 e_1_3_2_67_2 e_1_3_2_61_2 e_1_3_2_15_2 e_1_3_2_38_2 e_1_3_2_8_2 e_1_3_2_17_2 e_1_3_2_59_2 e_1_3_2_6_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_53_2 e_1_3_2_32_2 e_1_3_2_51_2 e_1_3_2_74_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_57_2 e_1_3_2_4_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_55_2 e_1_3_2_2_2 e_1_3_2_72_2 e_1_3_2_70_2 Margalit, A, Carolan, JC, Sheehan, D, Kavanagh, K (B48) 2020; 19 B26 Wiemann, P, Guo, C-J, Palmer, JM, Sekonyela, R, Wang, CCC, Keller, NP (B31) 2013; 110 Egeland, ES, Guillard, RRL, Liaaen-Jensen, S (B43) 1997; 44 Clasquin, MF, Melamud, E, Rabinowitz, JD (B29) 2012; 37 Netzker, T, Fischer, J, Weber, J, Mattern, DJ, König, CC, Valiante, V, Schroeckh, V, Brakhage, AA (B3) 2015; 6 Lind, AL, Smith, TD, Saterlee, T, Calvo, AM, Rokas, A (B25) 2016; 6 Seenivasan, A, Subhagar, S, Aravindan, R, Viruthagiri, T (B42) 2008; 70 (B72) 2020 Brookman, JL, Denning, DW (B61) 2000; 3 Zöhrer, J, Probst, M, Dumfort, S, Lenz, H, Pecenka, R, Insam, H, Ascher-Jenull, J (B45) 2021; 156 Mills, RF (B65) 1955; 13 Horikoshi, R, Goto, K, Mitomi, M, Oyama, K, Sunazuka, T, Ōmura, S (B71) 2017; 70 Cope, KR, Bascaules, A, Irving, TB, Venkateshwaran, M, Maeda, J, Garcia, K, Rush, TA, Ma, C, Labbé, J, Jawdy, S, Steigerwald, E, Setzke, J, Fung, E, Schnell, KG, Wang, Y, Schlief, N, Bücking, H, Strauss, SH, Maillet, F, Jargeat, P, Bécard, G, Puech-Pagès, V, Ané, J-M (B7) 2019; 31 Keller, N, Bok, J, Chung, D, Perrin, RM, Keats Shwab, E (B18) 2006; 44 Bok, JW, Keller, NP (B16) 2004; 3 Pfannenstiel, BT, Zhao, X, Wortman, J, Wiemann, P, Throckmorton, K, Spraker, JE, Soukup, AA, Luo, X, Lindner, DL, Lim, FY, Knox, BP, Haas, B, Fischer, GJ, Choera, T, Butchko, RAE, Bok, J-W, Affeldt, KJ, Keller, NP, Palmer, JM (B63) 2017; 8 Marburger, DA, Willbur, JF, Weber, ME, Ané, J-M, Kabbage, M, Conley, SP, Smith, DL (B14) 2018; 19 Page, L, Brin, S (B34) 1998; 30 Oláh, B, Brière, C, Bécard, G, Dénarié, J, Gough, C (B59) 2005; 44 Dénarié, J, Debellé, F, Promé, JC (B8) 1996; 65 Gould, AL, Zhang, V, Lamberti, L, Jones, EW, Obadia, B, Korasidis, N, Gavryushkin, A, Carlson, JM, Beerenwinkel, N, Ludington, WB (B56) 2018; 115 Pinheiro, EAA, Carvalho, JM, dos Santos, DCP, Feitosa, AdO, Marinho, PSB, Guilhon, GMSP, de Souza, ADL, da Silva, FMA, Marinho, AMDR (B68) 2013; 27 Raffa, N, Keller, NP (B19) 2019; 15 Keller, NP (B1) 2019; 17 Villalobos Solis, MI, Engle, NL, Spangler, MK, Cottaz, S, Fort, S, Maeda, J, Ané, J-M, Tschaplinski, TJ, Labbé, JL, Hettich, RL, Abraham, PE, Rush, TA (B6) 2022; 3 Kaminskyj, SGW (B62) 2001; 48 Mehedi, MAU, Molla, AH, Khondkar, P, Sultana, S, Islam, MA, Rashid, MA, Chowdhury, R (B49) 2010; 22 Tati, S, Davidow, P, McCall, A, Hwang-Wong, E, Rojas, IG, Cormack, B, Edgerton, M (B52) 2016; 12 Bignell, E, Cairns, TC, Throckmorton, K, Nierman, WC, Keller, NP (B54) 2016; 371 Hagiwara, D, Sakai, K, Suzuki, S, Umemura, M, Nogawa, T, Kato, N, Osada, H, Watanabe, A, Kawamoto, S, Gonoi, T, Kamei, K (B23) 2017; 12 Carper, DL, Weston, DJ, Barde, A, Timm, CM, Lu, T-Y, Burdick, LH, Jawdy, SS, Klingeman, DM, Robeson, MS, Veach, AM, Cregger, MA, Kalluri, UC, Schadt, CW, Podar, M, Doktycz, MJ, Pelletier, DA (B28) 2021; 6 Marcotullio, MC, Curini, M, Becerra, JX (B41) 2018; 23 Berthier, E, Lim, FY, Deng, Q, Guo, C-J, Kontoyiannis, DP, Wang, CCC, Rindy, J, Beebe, DJ, Huttenlocher, A, Keller, NP (B22) 2013; 9 Tautenhahn, R, Patti, GJ, Rinehart, D, Siuzdak, G (B30) 2012; 84 Ksebati, MB, Schmitz, FJ (B44) 1988; 53 Reece, E, Doyle, S, Greally, P, Renwick, J, McClean, S (B50) 2018; 9 Macchiavelli, RE, Brelles-Mariño, G (B58) 2004; 55 Panaccione, DG, Coyle, CM (B36) 2005; 71 Khokhani, D, Carrera Carriel, C, Vayla, S, Irving, TB, Stonoha-Arther, C, Keller, NP, Ané, J-M (B11) 2021; 75 Shadduck, JA (B66) 1980; 27 Rush, TA, Shrestha, HK, Gopalakrishnan Meena, M, Spangler, MK, Ellis, JC, Labbé, JL, Abraham, PE (B27) 2021; 2 Motulsky, HJ, Brown, RE (B74) 2006; 7 Calvo, AM, Wilson, RA, Bok, JW, Keller, NP (B32) 2002; 66 Maillet, F, Poinsot, V, André, O, Puech-Pagès, V, Haouy, A, Gueunier, M, Cromer, L, Giraudet, D, Formey, D, Niebel, A, Martinez, EA, Driguez, H, Bécard, G, Dénarié, J (B13) 2011; 469 Schimmel, TG, Coffman, AD, Parsons, SJ (B33) 1998; 64 Pousset, J-L, Kerharo, J, Maynart, G, Monseur, X, Cavé, A, Goutarel, R (B38) 1973; 12 Zihad, SMNK, Hasan, MT, Sultana, MS, Nath, S, Nahar, L, Rashid, MA, Uddin, SJ, Sarker, SD, Shilpi, JA (B39) 2022; 2022 D’Haeze, W, Holsters, M (B51) 2002; 12 Fidel, PL, Vazquez, JA, Sobel, JD (B53) 1999; 12 Henning, JA, Weston, DJ, Pelletier, DA, Timm, CM, Jawdy, SS, Classen, AT (B46) 2019; 106 Romsdahl, J, Wang, CCC (B20) 2019; 10 Jaiswal, SK, Mohammed, M, Ibny, FYI, Dakora, FD (B57) 2021; 4 Liang, Y, Tóth, K, Cao, Y, Tanaka, K, Espinoza, C, Stacey, G (B12) 2014; 204 Dowd, PF (B55) 1988; 47 Girardin, A, Wang, T, Ding, Y, Keller, J, Buendia, L, Gaston, M, Ribeyre, C, Gasciolli, V, Auriac, M-C, Vernié, T, Bendahmane, A, Ried, MK, Parniske, M, Morel, P, Vandenbussche, M, Schorderet, M, Reinhardt, D, Delaux, P-M, Bono, J-J, Lefebvre, B (B10) 2019; 29 Kosalec, I, Pepljnjak, S, Jandrlić, M (B24) 2005; 3 Djordjevic, MA, Bezos, A, Marmuse, L, Driguez, H, Samain, E, Vauzeilles, B, Beau, J-M, Kordbacheh, F, Rolfe, BG, Schwörer, R, Daines, AM, Gresshoff, PM, Parish, CR (B60) 2014; 9 Esteban, P, Redrado, S, Comas, L, Domingo, MP, Millán-Lou, MI, Seral, C, Algarate, S, Lopez, C, Rezusta, A, Pardo, J, Arias, M, Galvez, EM (B69) 2021; 13 Baccile, JA, Spraker, JE, Le, HH, Brandenburger, E, Gomez, C, Bok, JW, Macheleidt, J, Brakhage, AA, Hoffmeister, D, Keller, NP, Schroeder, FC (B40) 2016; 12 Rey, T, André, O, Nars, A, Dumas, B, Gough, C, Bottin, A, Jacquet, C (B15) 2019; 221 Genre, A, Chabaud, M, Balzergue, C, Puech-Pagès, V, Novero, M, Rey, T, Fournier, J, Rochange, S, Bécard, G, Bonfante, P, Barker, DG (B9) 2013; 198 Sprouffske, K, Wagner, A (B73) 2016; 17 Rush, TA, Puech-Pagès, V, Bascaules, A, Jargeat, P, Maillet, F, Haouy, A, Maës, AQ, Carriel, CC, Khokhani, D, Keller-Pearson, M, Tannous, J, Cope, KR, Garcia, K, Maeda, J, Johnson, C, Kleven, B, Choudhury, QJ, Labbé, J, Swift, C, O’Malley, MA, Bok, JW, Cottaz, S, Fort, S, Poinsot, V, Sussman, MR, Lefort, C, Nett, J, Keller, NP, Bécard, G, Ané, J-M (B5) 2020; 11 Frisvad, JC, Rank, C, Nielsen, KF, Larsen, TO (B17) 2009; 47 Qin, L, Li, B, Guan, J, Zhang, G (B70) 2009; 23 Lerouge, P, Roche, P, Faucher, C, Maillet, F, Truchet, G, Promé, JC, Dénarié, J (B4) 1990; 344 Atanasov, AG, Zotchev, SB, Dirsch, VM, Supuran, CT (B2) 2021; 20 Zhang, P, Nicholson, DE, Bujnicki, JM, Su, X, Brendle, JJ, Ferdig, M, Kyle, DE, Milhous, WK, Chiang, PK (B67) 2002; 9 Van De Veerdonk, FL, Gresnigt, MS, Romani, L, Netea, MG, Latgé, JP (B21) 2017; 15 Box, SJ, Hood, JD, Spear, SR (B37) 1979; 32 MacLean, B, Tomazela, DM, Shulman, N, Chambers, M, Finney, GL, Frewen, B, Kern, R, Tabb, DL, Liebler, DC, MacCoss, MJ (B64) 2010; 26 Spencer, SPE, Lowe, SA (B35) 2019; 7 Wang, J, Carper, DL, Burdick, LH, Shrestha, HK, Appidi, MR, Abraham, PE, Timm, CM, Hettich, RL, Pelletier, DA, Doktycz, MJ (B47) 2021; 19 |
| References_xml | – ident: e_1_3_2_69_2 doi: 10.1080/14786419.2012.750316 – ident: e_1_3_2_33_2 doi: 10.1128/MMBR.66.3.447-459.2002 – ident: e_1_3_2_56_2 doi: 10.1111/j.1570-7458.1988.tb02283.x – ident: e_1_3_2_30_2 doi: 10.1002/0471250953.bi1411s37 – ident: e_1_3_2_55_2 doi: 10.1098/rstb.2016.0023 – ident: e_1_3_2_4_2 doi: 10.3389/fmicb.2015.00299 – ident: e_1_3_2_9_2 doi: 10.1146/annurev.bi.65.070196.002443 – ident: e_1_3_2_27_2 doi: 10.1101/2022.08.11.503656 – ident: e_1_3_2_65_2 doi: 10.1093/bioinformatics/btq054 – ident: e_1_3_2_34_2 doi: 10.1128/AEM.64.10.3707-3712.1998 – ident: e_1_3_2_72_2 doi: 10.1038/ja.2016.155 – ident: e_1_3_2_5_2 doi: 10.1038/344781a0 – ident: e_1_3_2_61_2 doi: 10.1371/journal.pone.0112635 – ident: e_1_3_2_75_2 doi: 10.1186/1471-2105-7-123 – ident: e_1_3_2_63_2 doi: 10.4148/1941-4765.1175 – ident: e_1_3_2_52_2 doi: 10.1093/glycob/12.6.79r – ident: e_1_3_2_13_2 doi: 10.1111/nph.12898 – volume-title: R Foundation for Statistical Computing year: 2020 ident: e_1_3_2_73_2 – ident: e_1_3_2_28_2 doi: 10.3389/ffunb.2021.716511 – ident: e_1_3_2_68_2 doi: 10.1007/BF02256576 – ident: e_1_3_2_41_2 doi: 10.1038/nchembio.2061 – ident: e_1_3_2_7_2 doi: 10.3389/ffunb.2022.808578 – ident: e_1_3_2_48_2 doi: 10.1016/j.csbj.2021.03.034 – ident: e_1_3_2_19_2 doi: 10.1080/13693780600835773 – ident: e_1_3_2_36_2 doi: 10.1002/ccr3.2516 – ident: e_1_3_2_45_2 doi: 10.1021/jo00252a008 – ident: e_1_3_2_47_2 doi: 10.1002/ajb2.1373 – ident: e_1_3_2_67_2 doi: 10.1111/j.1550-7408.1980.tb04681.x – ident: e_1_3_2_3_2 doi: 10.1038/s41573-020-00114-z – ident: e_1_3_2_46_2 doi: 10.1016/j.ibiod.2020.105133 – ident: e_1_3_2_66_2 doi: 10.1099/00221287-13-1-39 – ident: e_1_3_2_44_2 doi: 10.1016/S0031-9422(96)00650-4 – ident: e_1_3_2_58_2 doi: 10.3389/fsufs.2020.619676 – ident: e_1_3_2_70_2 doi: 10.3390/toxins13020085 – ident: e_1_3_2_43_2 doi: 10.4103/0250-474X.49087 – ident: e_1_3_2_54_2 doi: 10.1128/CMR.12.1.80 – ident: e_1_3_2_39_2 doi: 10.1016/0031-9422(73)85148-9 – ident: e_1_3_2_42_2 doi: 10.3390/molecules23081976 – ident: e_1_3_2_17_2 doi: 10.1128/EC.3.2.527-535.2004 – ident: e_1_3_2_59_2 doi: 10.1093/jxb/erh261 – ident: e_1_3_2_29_2 doi: 10.1128/mSystems.01306-20 – ident: e_1_3_2_51_2 doi: 10.3389/fmicb.2018.01205 – ident: e_1_3_2_12_2 doi: 10.1146/annurev-micro-051921-114809 – ident: e_1_3_2_21_2 doi: 10.1039/c9md00054b – ident: e_1_3_2_23_2 doi: 10.1371/journal.ppat.1003289 – ident: e_1_3_2_60_2 doi: 10.1111/j.1365-313X.2005.02522.x – ident: e_1_3_2_14_2 doi: 10.1038/nature09622 – ident: e_1_3_2_8_2 doi: 10.1105/tpc.18.00676 – ident: e_1_3_2_22_2 doi: 10.1038/nrmicro.2017.90 – ident: e_1_3_2_2_2 doi: 10.1038/s41579-018-0121-1 – ident: e_1_3_2_18_2 doi: 10.1080/13693780802307720 – ident: e_1_3_2_40_2 doi: 10.1155/2022/9600079 – ident: e_1_3_2_35_2 doi: 10.1016/S0169-7552(98)00110-X – ident: e_1_3_2_74_2 doi: 10.1186/s12859-016-1016-7 – ident: e_1_3_2_11_2 doi: 10.1016/j.cub.2019.11.038 – ident: e_1_3_2_57_2 doi: 10.1073/pnas.1809349115 – ident: e_1_3_2_49_2 doi: 10.1074/mcp.RA120.002059 – ident: e_1_3_2_6_2 doi: 10.1038/s41467-020-17615-5 – volume: 22 start-page: 2611 year: 2010 ident: e_1_3_2_50_2 article-title: Pseurotin a: an antibacterial secondary metabolite from aspergillus fumigatus publication-title: Asian J Chem – ident: e_1_3_2_38_2 doi: 10.7164/antibiotics.32.1239 – ident: e_1_3_2_26_2 doi: 10.1534/g3.116.033084 – ident: e_1_3_2_31_2 doi: 10.1021/ac300698c – ident: e_1_3_2_62_2 doi: 10.1016/S1369-5274(00)00124-7 – ident: e_1_3_2_53_2 doi: 10.1371/journal.ppat.1005522 – ident: e_1_3_2_71_2 doi: 10.1080/14786410801972813 – ident: e_1_3_2_64_2 doi: 10.1128/mBio.01246-17 – ident: e_1_3_2_15_2 doi: 10.1094/PHP-10-17-0058-RS – ident: e_1_3_2_20_2 doi: 10.1371/journal.ppat.1007606 – ident: e_1_3_2_10_2 doi: 10.1111/nph.12146 – volume: 3 start-page: 269 year: 2005 ident: e_1_3_2_25_2 article-title: Influence of media and temperature on gliotoxin production in Aspergillus fumigatus strains publication-title: Arh Hig Rada Toksikol – ident: e_1_3_2_37_2 doi: 10.1128/AEM.71.6.3106-3111.2005 – ident: e_1_3_2_16_2 doi: 10.1111/nph.15574 – ident: e_1_3_2_32_2 doi: 10.1073/pnas.1313258110 – ident: e_1_3_2_24_2 doi: 10.1371/journal.pone.0177050 – volume: 12 year: 2016 ident: B52 article-title: Candida glabrata binding to Candida albicans hyphae enables its development in oropharyngeal candidiasis publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1005522 – volume: 198 start-page: 190 year: 2013 end-page: 202 ident: B9 article-title: Short-chain chitin oligomers from arbuscular mycorrhizal fungi trigger nuclear Ca2+ spiking in Medicago truncatula roots and their production is enhanced by strigolactone publication-title: New Phytol doi: 10.1111/nph.12146 – volume: 19 start-page: 46 year: 2018 end-page: 53 ident: B14 article-title: Characterizing the effect of foliar lipo-chitooligosaccharide application on sudden death syndrome and sclerotinia stem rot in soybean publication-title: Plant Heal Prog doi: 10.1094/PHP-10-17-0058-RS – volume: 19 start-page: 1917 year: 2021 end-page: 1927 ident: B47 article-title: Formation, characterization and modeling of emergent synthetic microbial communities publication-title: Comput Struct Biotechnol J doi: 10.1016/j.csbj.2021.03.034 – volume: 65 start-page: 503 year: 1996 end-page: 535 ident: B8 article-title: Rhizobium lipo-chitooligosaccharide nodulation factors: Signaling molecules mediating recognition and morphogenesis publication-title: Annu Rev Biochem doi: 10.1146/annurev.bi.65.070196.002443 – volume: 204 start-page: 289 year: 2014 end-page: 296 ident: B12 article-title: Lipochitooligosaccharide recognition: an ancient story publication-title: New Phytol doi: 10.1111/nph.12898 – volume: 47 start-page: S53 year: 2009 end-page: S71 ident: B17 article-title: Metabolomics of Aspergillus fumigatus publication-title: Med Mycol doi: 10.1080/13693780802307720 – volume: 27 start-page: 1633 year: 2013 end-page: 1638 ident: B68 article-title: Antibacterial activity of alkaloids produced by endophytic fungus Aspergillus sp. EJC08 isolated from medical plant Bauhinia guianensis publication-title: Nat Prod Res doi: 10.1080/14786419.2012.750316 – volume: 11 start-page: 3897 year: 2020 ident: B5 article-title: Lipo-chitooligosaccharides as regulatory signals of fungal growth and development publication-title: Nat Commun doi: 10.1038/s41467-020-17615-5 – volume: 26 start-page: 966 year: 2010 end-page: 968 ident: B64 article-title: Skyline: an open source document editor for creating and analyzing targeted proteomics experiments publication-title: Bioinformatics doi: 10.1093/bioinformatics/btq054 – volume: 47 start-page: 69 year: 1988 end-page: 71 ident: B55 article-title: Synergism of aflatoxin B1 toxicity with the co-occurring fungal metabolite kojic acid to two caterpillars publication-title: Entomol. Exp. Appl – volume: 13 start-page: 85 year: 2021 ident: B69 article-title: In vitro and in vivo antibacterial activity of gliotoxin alone and in combination with antibiotics against Staphylococcus aureus publication-title: Toxins (Basel) doi: 10.3390/toxins13020085 – volume: 2022 start-page: 9600079 year: 2022 ident: B39 article-title: Isolation and characterization of antibacterial compounds from Aspergillus fumigatus: an endophytic fungus from a mangrove plant of the Sundarbans publication-title: Evid Based Complement Alternat Med – volume: 44 start-page: 83 year: 2006 end-page: 85 ident: B18 article-title: LaeA, a global regulator of Aspergillus toxins publication-title: Med Mycol doi: 10.1080/13693780600835773 – ident: B26 article-title: Gopalakrishnan Meena M , Lane MJ , Tannous J , Carrell AA , Abraham PE , Giannone RJ , Ané J-M , Keller NP , Labbé JL , Kainer D , Jacobson DA , Rush TA . 2022 . A guidance into the fungal metabolomic abyss: network analysis for revealing relationships between exogenous compounds and their outputs . bioRxiv . doi: 10.1101/2022.08.11.503656 . – volume: 84 start-page: 5035 year: 2012 end-page: 5039 ident: B30 article-title: XCMS online: a web-based platform to process untargeted metabolomic data publication-title: Anal Chem doi: 10.1021/ac300698c – volume: 8 year: 2017 ident: B63 article-title: Revitalization of a forward genetic screen identifies three new regulators of fungal secondary metabolism in the genus Aspergillus publication-title: mBio doi: 10.1128/mBio.01246-17 – volume: 3 start-page: 269 year: 2005 end-page: 273 ident: B24 article-title: Influence of media and temperature on gliotoxin production in Aspergillus fumigatus strains publication-title: Arh Hig Rada Toksikol – volume: 7 start-page: 2433 year: 2019 end-page: 2442 ident: B35 article-title: Ergometrine for postpartum hemorrhage and associated myocardial ischemia: two case reports and a review of the literature publication-title: Clin Case Rep doi: 10.1002/ccr3.2516 – volume: 3 start-page: 527 year: 2004 end-page: 535 ident: B16 article-title: LaeA, a regulator of secondary metabolism in Aspergillus spp publication-title: Eukaryot Cell doi: 10.1128/EC.3.2.527-535.2004 – volume: 12 start-page: 79R year: 2002 end-page: 105R ident: B51 article-title: Nod factor structures, responses, and perception during initiation of nodule development publication-title: Glycobiology doi: 10.1093/glycob/12.6.79r – volume: 4 start-page: 619676 year: 2021 ident: B57 article-title: Rhizobia as a source of plant growth-promoting molecules: potential applications and possible operational mechanisms publication-title: Front Sustain Food Syst doi: 10.3389/fsufs.2020.619676 – volume: 23 start-page: 1976 year: 2018 ident: B41 article-title: An ethnopharmacological, phytochemical and pharmacological review on lignans from Mexican Bursera spp publication-title: Molecules doi: 10.3390/molecules23081976 – volume: 13 start-page: 39 year: 1955 end-page: 44 ident: B65 article-title: The action of fumagillin on a bacteriophage of Staphylococcus aureus publication-title: J Gen Microbiol doi: 10.1099/00221287-13-1-39 – volume: 12 start-page: 80 year: 1999 end-page: 96 ident: B53 article-title: Candida glabrata: Review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans publication-title: Clin Microbiol Rev doi: 10.1128/CMR.12.1.80 – volume: 20 start-page: 200 year: 2021 end-page: 216 ident: B2 article-title: Natural products in drug discovery: advances and opportunities publication-title: Nature Rev Drug Discovery doi: 10.1038/s41573-020-00114-z – volume: 7 start-page: 123 year: 2006 ident: B74 article-title: Detecting outliers when fitting data with nonlinear regression: a new method based on robust nonlinear regression and the false discovery rate publication-title: BMC Bioinformatics doi: 10.1186/1471-2105-7-123 – volume: 70 start-page: 701 year: 2008 end-page: 709 ident: B42 article-title: Microbial production and biomedical applications of lovastatin publication-title: Indian J Pharm Sci – volume: 55 start-page: 2635 year: 2004 end-page: 2640 ident: B58 article-title: Nod factor-treated Medicago truncatula roots and seeds show an increased number of nodules when inoculated with a limiting population of Sinorhizobium meliloti publication-title: J Exp Bot doi: 10.1093/jxb/erh261 – volume: 44 start-page: 195 year: 2005 end-page: 207 ident: B59 article-title: Nod factors and a diffusible factor from arbuscular mycorrhizal fungi stimulate lateral root formation in Medicago truncatula via the DMI1/DMI2 signalling pathway publication-title: Plant J doi: 10.1111/j.1365-313X.2005.02522.x – volume: 3 start-page: 468 year: 2000 end-page: 474 ident: B61 article-title: Molecular genetics in Aspergillus fumigatus publication-title: Curr Opin Microbiol doi: 10.1016/S1369-5274(00)00124-7 – volume: 75 start-page: 583 year: 2021 end-page: 607 ident: B11 article-title: Deciphering the chitin code in plant symbiosis, defense, and microbial networks publication-title: Annu Rev Microbiol doi: 10.1146/annurev-micro-051921-114809 – volume: 17 start-page: 167 year: 2019 end-page: 180 ident: B1 article-title: Fungal secondary metabolism: regulation, function and drug discovery publication-title: Nat Rev Microbiol doi: 10.1038/s41579-018-0121-1 – volume: 29 start-page: 4249 year: 2019 end-page: 4259.e5 ident: B10 article-title: LCO receptors involved in arbuscular mycorrhiza are functional for rhizobia perception in legumes publication-title: Curr Biol doi: 10.1016/j.cub.2019.11.038 – volume: 12 year: 2017 ident: B23 article-title: Temperature during conidiation affects stress tolerance, pigmentation, and trypacidin accumulation in the conidia of the airborne pathogen Aspergillus fumigatus publication-title: PLoS One doi: 10.1371/journal.pone.0177050 – volume: 110 start-page: 17065 year: 2013 end-page: 17070 ident: B31 article-title: Prototype of an intertwined secondary-metabolite supercluster publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1313258110 – volume: 27 start-page: 202 year: 1980 end-page: 208 ident: B66 article-title: Effect of fumagillin on in vitro multiplication of Encephalitozoon cuniculi publication-title: J Protozool doi: 10.1111/j.1550-7408.1980.tb04681.x – volume: 156 start-page: 105133 year: 2021 ident: B45 article-title: Molecular monitoring of the poplar wood chip microbiome as a function of storage strategy publication-title: International Biodeterioration & Biodegradation doi: 10.1016/j.ibiod.2020.105133 – volume: 70 start-page: 272 year: 2017 end-page: 276 ident: B71 article-title: Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening publication-title: J Antibiot (Tokyo) doi: 10.1038/ja.2016.155 – volume: 15 start-page: 661 year: 2017 end-page: 674 ident: B21 article-title: Aspergillus fumigatus morphology and dynamic host interactions publication-title: Nat Rev Microbiol doi: 10.1038/nrmicro.2017.90 – volume: 106 start-page: 1423 year: 2019 end-page: 1434 ident: B46 article-title: Relatively rare root endophytic bacteria drive plant resource allocation patterns and tissue nutrient concentration in unpredictable ways publication-title: Am J Bot doi: 10.1002/ajb2.1373 – volume: 6 start-page: 4023 year: 2016 end-page: 4033 ident: B25 article-title: Regulation of secondary metabolism by the velvet complex is temperature-responsive in Aspergillus publication-title: G3 (Bethesda) doi: 10.1534/g3.116.033084 – volume: 371 start-page: 20160023 year: 2016 ident: B54 article-title: Secondary metabolite arsenal of an opportunistic pathogenic fungus publication-title: Philos Trans R Soc B doi: 10.1098/rstb.2016.0023 – volume: 44 start-page: 1087 year: 1997 end-page: 1097 ident: B43 article-title: Additional carotenoid prototype respresentatives and a general chemosystematic evaluation of carotenoids in prasinophyceae (chlorophyta) publication-title: Phytochemistry doi: 10.1016/S0031-9422(96)00650-4 – volume: 115 start-page: E11951 year: 2018 end-page: E11960 ident: B56 article-title: Microbiome interactions shape host fitness publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.1809349115 – volume: 10 start-page: 840 year: 2019 end-page: 866 ident: B20 article-title: Recent advances in the genome mining of Aspergillus secondary metabolites (covering 2012–2018) publication-title: Medchemcomm doi: 10.1039/c9md00054b – volume: 30 start-page: 107 year: 1998 end-page: 117 ident: B34 article-title: The anatomy of a large-scale hypertextual Web search engine publication-title: Comput Networks doi: 10.1016/S0169-7552(98)00110-X – volume: 12 start-page: 2308 year: 1973 end-page: 2310 ident: B38 article-title: La borrerine: nouvel alcaloïde isolé du Borreria verticillata publication-title: Phytochemistry doi: 10.1016/0031-9422(73)85148-9 – volume: 344 start-page: 781 year: 1990 end-page: 784 ident: B4 article-title: Symbiotic host-specificity of Rhizobium meliloti is determined by a sulphated and acylated glucosamine oligosaccharide signal publication-title: Nature doi: 10.1038/344781a0 – volume: 15 year: 2019 ident: B19 article-title: A call to arms: mustering secondary metabolites for success and survival of an opportunistic pathogen publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1007606 – volume: 66 start-page: 447 year: 2002 end-page: 459 ident: B32 article-title: Relationship between secondary metabolism and fungal development publication-title: Microbiol Mol Biol Rev doi: 10.1128/MMBR.66.3.447-459.2002 – volume: 71 start-page: 3106 year: 2005 end-page: 3111 ident: B36 article-title: Abundant respirable ergot alkaloids from the common airborne fungus Aspergillus fumigatus publication-title: Appl Environ Microbiol doi: 10.1128/AEM.71.6.3106-3111.2005 – volume: 3 year: 2022 ident: B6 article-title: Expanding the biological role of lipo-chitooligosaccharides and chitooligosaccharides in Laccaria bicolor growth and development publication-title: Front Fungal Biol doi: 10.3389/ffunb.2022.808578 – volume: 12 start-page: 419 year: 2016 end-page: 424 ident: B40 article-title: Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus publication-title: Nat Chem Biol doi: 10.1038/nchembio.2061 – volume: 9 start-page: 1205 year: 2018 ident: B50 article-title: Aspergillus fumigatus inhibits Pseudomonas aeruginosa in co-culture: implications of a mutually antagonistic relationship on virulence and inflammation in the CF airway publication-title: Front Microbiol doi: 10.3389/fmicb.2018.01205 – volume: 9 start-page: 34 year: 2002 end-page: 40 ident: B67 article-title: Angiogenesis inhibitors specific for methionine aminopeptidase 2 as drugs for malaria and leishmaniasis publication-title: J Biomed Sci doi: 10.1007/BF02256576 – volume: 37 start-page: 14.11 year: 2012 ident: B29 article-title: LC-MS data processing with MAVEN: A metabolomic analysis and visualization engine publication-title: Curr Protoc Bioinforma doi: 10.1002/0471250953.bi1411s37 – volume: 64 start-page: 3707 year: 1998 end-page: 3712 ident: B33 article-title: Effect of butyrolactone I on the producing fungus, Aspergillus terreus publication-title: Appl Environ Microbiol doi: 10.1128/AEM.64.10.3707-3712.1998 – volume: 2 year: 2021 ident: B27 article-title: Bioprospecting Trichoderma: a systematic roadmap to screen genomes and natural products for biocontrol applications publication-title: Front Fungal Biol doi: 10.3389/ffunb.2021.716511 – volume: 469 start-page: 58 year: 2011 end-page: 63 ident: B13 article-title: Fungal lipochitooligosaccharide symbiotic signals in arbuscular mycorrhiza publication-title: Nature doi: 10.1038/nature09622 – volume: 31 start-page: 2386 year: 2019 end-page: 2410 ident: B7 article-title: The ectomycorrhizal fungus Laccaria bicolor produces lipochitooligosaccharides and uses the common symbiosis pathway to colonize populus roots publication-title: Plant Cell doi: 10.1105/tpc.18.00676 – volume: 32 start-page: 1239 year: 1979 end-page: 1247 ident: B37 article-title: Four further antibiotics related to olivanic acid produced by Streptomyces olivaceus: fermentation, isolation, characterisation and biosynthetic studies publication-title: J Antibiot (Tokyo) doi: 10.7164/antibiotics.32.1239 – volume: 19 start-page: 1346 year: 2020 end-page: 1359 ident: B48 article-title: The Aspergillus fumigatus secretome alters the proteome of Pseudomonas aeruginosa to stimulate bacterial growth: implications for co-infection publication-title: Mol Cell Proteomics doi: 10.1074/mcp.RA120.002059 – volume: 53 start-page: 3926 year: 1988 end-page: 3929 ident: B44 article-title: Minabeolides: a group of with anolides from soft coral, Minabea sp publication-title: J Org Chem doi: 10.1021/jo00252a008 – volume: 22 start-page: 2611 year: 2010 end-page: 2614 ident: B49 article-title: Pseurotin a: an antibacterial secondary metabolite from aspergillus fumigatus publication-title: Asian J Chem – volume: 6 start-page: 299 year: 2015 ident: B3 article-title: Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters publication-title: Front Microbiol doi: 10.3389/fmicb.2015.00299 – year: 2020 ident: B72 article-title: R: A language and environment for statistical computing publication-title: R Foundation for Statistical Computing ;Vienna, Austria – volume: 6 year: 2021 ident: B28 article-title: Cultivating the bacterial microbiota of Populus roots publication-title: mSystems doi: 10.1128/mSystems.01306-20 – volume: 9 year: 2014 ident: B60 article-title: Lipo-chitin oligosaccharides, plant symbiosis signalling molecules that modulate mammalian angiogenesis in vitro publication-title: PLoS One doi: 10.1371/journal.pone.0112635 – volume: 17 start-page: 172 year: 2016 ident: B73 article-title: Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves publication-title: BMC Bioinformatics doi: 10.1186/s12859-016-1016-7 – volume: 23 start-page: 309 year: 2009 end-page: 318 ident: B70 article-title: In vitro synergistic antibacterial activities of helvolic acid on multi-drug resistant Staphylococcus aureus publication-title: Nat Prod Res doi: 10.1080/14786410801972813 – volume: 48 start-page: 25 year: 2001 end-page: 31 ident: B62 article-title: Fundamentals of growth, storage, genetics and microscopy of Aspergillus nidulans publication-title: Fungal Genetics Rep doi: 10.4148/1941-4765.1175 – volume: 221 start-page: 743 year: 2019 end-page: 749 ident: B15 article-title: Lipo-chitooligosaccharide signalling blocks a rapid pathogen-induced ROS burst without impeding immunity publication-title: New Phytol doi: 10.1111/nph.15574 – volume: 9 year: 2013 ident: B22 article-title: Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1003289 |
| SSID | ssj0001637129 |
| Score | 2.2609262 |
| Snippet | The activation of silent biosynthetic gene clusters (BGC) for the identification and characterization of novel fungal secondary metabolites is a perpetual... Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with beneficial... ABSTRACT Lipo-chitooligosaccharides (LCOs) are historically known for their role as microbial-derived signaling molecules that shape plant symbiosis with... |
| SourceID | doaj pubmedcentral osti hal proquest asm2 pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | e0105222 |
| SubjectTerms | Aspergillus bacteria Bacteriology BASIC BIOLOGICAL SCIENCES Biochemistry, Molecular Biology biosynthetic gene clusters Chitin Chitosan - pharmacology Ecology, environment Humans Life Sciences lipo-chitooligosaccharides Microbiology and Parasitology Mycology Mycorrhizae Oligosaccharides - pharmacology Physiology and Metabolism Research Article secondary metabolites Symbiosis synergism |
| SummonAdditionalLinks | – databaseName: American Society for Microbiology Open Access dbid: AAUOK link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3da9RAEF_KFcEX8du0tkQRBCE1u5vbZB-vxfPQnvrQg74t-5Um0CbFpIL-9c7k4zRSiq_Z3WzYmdn5bWbnN4S8odamSIoSOUl5lGjhIsOEjqThXBuXWOrwf8f6i1htkk_n8_MdIsZcmGEFmyPdXHWB_K1ls-z9Vc9u3BxhWUcWMdh6d-cA-UGzdxeLzdfPf_6uCJ6CJxvCmLeOhT0Y5mATf9TR9oOXKfBS5KwGI7sNeP57f_Ivh7R8SB4MSDJc9KJ_RHZ89Zjc62tL_nxCLk7L6zo6KcBi68vyom60xQyr0vkmxHod1odD7fnyl3fhEowe3rb2LWgF5iWH3_pq3k14Vug2XNcOC3358Lind4a-H-EE3xZPyWb54exkFQ1VFSIN4K2NpBWJhrVxmDwZOwBoztLcedgac8fnqXFxznUKlpqDIzOUG2eElZmGg4X2OuHPyKyqK_-ChMZnmhmPwVSd5H6exVILmxhL4VxtHQ_IW1xiNQpVdScOlqlRGKoThmIsIPEoBWUHcnKskXF515B32yHXPTPHXZ2PUbTbjkiq3T0AFVODjSpQJOGpMTZmMkmlNrEwsQd8iBxnjsUBeQ2KMXnHanGq8FnMZSYBPP2gAdlHvVEAYJCF1-J1Jdsqiiw5FFbk1ahOCuwYgzO68vVNo5CpUaQxGE5AnvfqtZ0JQ8VccmhJJ4o3-ZRpS1UWHVc4oM1EZnTvvyWxT-4zzPDobuy8JLP2-40_ANzVmsPByH4DrfUtAg priority: 102 providerName: American Society for Microbiology – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3da9RAEF_KieCL-G1alSiCIKRmd3NJ9kGkLZ6H9MSHHvRt2a9cAtekXtLS-tc7k4_DyNEnXze7-diZ2ZnJ7vx-hLynxiQIihJYQXkQqdgGmsUqEJpzpW1kqMX_HYsf8XwZfT-fnu-Rgd6qn8B6Z2qHfFLLzfrw5tftFzD4z10BTPrpogM9rg-R7ZEFDFbke-CYGCr5oo_2218uMU-gtd_b3DkSFmZVX7CRk2qx_MH15HhSclKB5e2KRv89VPmXl5o9Ig_78NI_6vThMdlz5RNyvyOcvH1KVqfFZRWc5GDG1bpYVbUyWHZVWFf7SOJhnN8T0he_nfVnsBLA3RauAVXBYmX_Z0fxXftnuWr8RWWR_cv5xx3mM_T9Bml9kz8jy9nXs5N50FMtBAoiuiYQJo4UzI3FisrQQtRmDc2sg_Uys3yaaBtmXCVgvhl4N025tjo2IlWQbSinIv6cTMqqdC-Jr12qmHa4w6qizE3TUKjYRNpQSLaN5R75gFMsB1HLNg1hqRyEIVthSMY8Eg5SkKZHLEfijPVdQz5uh1x2cB13dT5G0W47ItJ221BtVrI3XAneInZUaxMyESVC6TDWoYOgEYHPLAs98g4UY3SP-dGpxLaQi1RARHVNPXKAeiMhqkFoXoNnmEwjKULnUJiRt4M6STBu3LFRpauuaonwjXESgjV55EWnXtsn4f4xFxyuJCPFG73K-EpZ5C2AOISgkUjp_v_4_gPygGFFSHvC5xWZNJsr9xritEa_aa3vD3ecPfk priority: 102 providerName: Scholars Portal |
| Title | Lipo-Chitooligosaccharides Induce Specialized Fungal Metabolite Profiles That Modulate Bacterial Growth |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/36453934 https://journals.asm.org/doi/10.1128/msystems.01052-22 https://www.proquest.com/docview/2744670774 https://hal.science/hal-03989151 https://www.osti.gov/servlets/purl/1902813 https://pubmed.ncbi.nlm.nih.gov/PMC9764981 https://doaj.org/article/8766e1bbc029479ab06b0e6231809d20 |
| Volume | 7 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVABX databaseName: American Society for Microbiology Open Access customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: AAUOK dateStart: 20160223 isFulltext: true titleUrlDefault: https://journals.asm.org/ providerName: American Society for Microbiology – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: KQ8 dateStart: 20160101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries – providerCode: PRVAON databaseName: DOAJ Open Access Full Text customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: DOA dateStart: 20160101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: M~E dateStart: 20160101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVAQN databaseName: PubMed Central customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: RPM dateStart: 20160101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: 7X7 dateStart: 20150101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: http://www.proquest.com/pqcentral?accountid=15518 eissn: 2379-5077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: BENPR dateStart: 20150101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVFZP databaseName: Scholars Portal Journals: Open Access customDbUrl: eissn: 2379-5077 dateEnd: 20250531 omitProxy: true ssIdentifier: ssj0001637129 issn: 2379-5077 databaseCode: M48 dateStart: 20160101 isFulltext: true titleUrlDefault: http://journals.scholarsportal.info providerName: Scholars Portal |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3da9RAEF_0RPBF_G5aPaIIghCb3c0l2ce70vPQXi3Sg3tb9itNoE2KSQv61zuT5I6LSH3xJYFk87Uzk5nZnf39CHlPjUkQFCWwgvIgUrENNItVIDTnStvIUIvjHcvTeLGKvqwn6x2qL6wJ6-CBu447BGuNHdXahExEiVA6jHXowGkj8JRlbbYObmwnmWpHV2KegCfrpzHhH3x41SEj15-QEpIFSJY7UvUVG_ijFrYfvEyORZGjCozsb4Hnn_WTOw5p_oQ87iNJf9p9wVNyz5XPyMOOW_Lnc3JxUlxXwVEOFltdFhdVrQyusCqsq33k6zDO77nni1_O-nMwerjb0jWgFbgu2T_r2Lxr_zxXjb-sLBJ9OX_WwTtD28-QwTf5C7KaH58fLYKeVSFQELw1gTBxpKBvLC6eDC0EaNbQzDr4NWaWTxJtw4yrBCw1A0emKddWx0akChIL5VTEX5JRWZVuj_japYpph5OpKsrcBCSiYhNpQyGvNpZ75AN2sezNopZtxsFSuRGGbIUhGfNIuJGCND04OXJkXN51ycftJdcdMsddjWco2m1DBNVuD4CqyV7V5L9UzSPvQDEG91hMTyQeC7lIBQRPt9QjB6g3EgIYROE1WK5kGkkRJYdCj7zdqJMEO8bJGVW66qaWiNQYJyEYjkdedeq1fRJOFXPB4UwyULzBqwzPlEXeYoVDtBmJlO7_j-8_II8YLv5oi3lek1Hz48a9gZCs0WNyP1knY_JgOl19-wr72fHp2fdxa5OwXUbpb2RxOT0 |
| linkProvider | Directory of Open Access Journals |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELdQJwQviG_C-AgICQkpwx9pEj92E6WwdvDQSnuz_JUlqEsmkiHBX89dkhaKponXxHYi3_18Z5_vd4S8YdamSIoSOclEFOvERYYnOpJGCG1cbJnD847FSTJbxZ9Px6fDrUrMhfmGdXnXzYFuzrs4PgIbD6KHeoTZ-_Oe4bg5wNKOPOKw_O6NuaR8RPYmk9WX4z8nLIlIwZoNocwr-8I6DB_iOzapo-4HS1PgxchRDUC7yvn89w7lX0ZpepfcGbzJcNKL_x654av75GZfX_LnA3I2Ly_q6KgA1Nbr8qxutMUsq9L5JsSaHdaHQ_358pd34RSAD6MtfAuagbnJ4de-oncTLgvdhovaYbEvHx72FM_Q9iPs4tviIVlNPyyPZtFQWSHS4MC1kbRJrGFuHCZQUgdOmrMsdx6Wx9yJcWoczYVOAa05GDPDhHEmsTLTsLnQXsfiERlVdeWfkND4THPjMaCq49yPMyp1YmNjGeytrRMBeYtTrAZoNKrbdfBMbYShOmEozgNCN1JQdiAoxzoZ6-u6vNt2uejZOa5rfIii3TZEYu3uAeiZGnCqwDgknhljKZdxKrWhiaEefETkOXOcBuQ1KMbOGLPJXOEzKmQmwYH6wQKyj3qjwIlBJl6LV5Zsqxgy5TCYkVcbdVKAZQzQ6MrXl41CtsYkpQCegDzu1Wv7JQwXCyngTbqjeDu_svumKouOLxw8zlhm7Ol_S-IluTVbLuZq_unkeJ_c5pjx0d3geUZG7fdL_xz8sNa8GAD3G1mFMVM |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9NAEF6hVCAuiDemPAxCQkJyuw_H9h7TQgg0KT00Um-rfbm21NoRdpHg1zNjO4GgquJq79rWzszOt56Zbwh5x6xNkRQlcpKJKNaJiwxPdCSNENq42DKH_zsWx8lsGX89G58NWZVYCzOsYLOnm8sukI-WvXL50I8w27_sGY6bPWztyCMO2-_OmGcZaPTOZLL8dvTnD0siUvBmQyjz2rmwD8N7-JZP6qj7wdMUmBg5qsHQrgOf_-ZQ_uWUpvfJvQFNhpNe_A_ILV89JLf7_pI_H5Hzebmqo8MCrLa-KM_rRlussiqdb0Ls2WF9OPSfL395F07B8OFpC9-CZmBtcnjSd_RuwtNCt-Gidtjsy4cHPcUzjP0Mp_i2eEyW00-nh7No6KwQaQBwbSRtEmtYG4cFlNQBSHOW5c7D9pg7MU6No7nQKVhrDs7MMGGcSazMNBwutNexeEJGVV35ZyQ0PtPceAyo6jj344xKndjYWAZna-tEQN7jEqu1YFV36uCZWgtDdcJQnAeErqWg7EBQjn0yLm6a8mEzZdWzc9w0-ABFuxmIxNrdBVAzNdipAueQeGaMpVzGqdSGJoZ6wIjIc-Y4DchbUIytZ8wmc4XXqJCZBAD1gwVkF_VGAYhBJl6LKUu2VQyZchisyJu1OimwZQzQ6MrXV41CtsYkpWA8AXnaq9fmTRguFlLAnXRL8bY-ZftOVRYdXzggzlhm7Pl_S-I1uXPycarmX46PdsldjgUfXQLPCzJqv1_5lwDDWvNqsLffRn4xAQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Lipo-Chitooligosaccharides+Induce+Specialized+Fungal+Metabolite+Profiles+That+Modulate+Bacterial+Growth&rft.jtitle=mSystems&rft.au=Tom%C3%A1s+A.+Rush&rft.au=Joanna+Tannous&rft.au=Matthew+J.+Lane&rft.au=Muralikrishnan+Gopalakrishnan+Meena&rft.date=2022-12-01&rft.pub=American+Society+for+Microbiology&rft.eissn=2379-5077&rft.volume=7&rft.issue=6&rft_id=info:doi/10.1128%2Fmsystems.01052-22&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_8766e1bbc029479ab06b0e6231809d20 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2379-5077&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2379-5077&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2379-5077&client=summon |