Intrapulmonary Pharmacokinetics of Laninamivir, a Neuraminidase Inhibitor, after a Single Nebulized Administration of Laninamivir Octanoate in Healthy Japanese Subjects - Toyama, Kaoru; Furuie, Hidetoshi; Ishizuka, Hitoshi (Antimicrobial Agents and Chemotherapy, 2018)
Keywords: Administration, Inhalation; Adult; Antiviral Agents; Antiviral Agents - administration & dosage; Antiviral Agents - adverse effects; Antiviral Agents - pharmacokinetics; Asian People; Bronchoalveolar Lavage Fluid; Bronchoalveolar Lavage Fluid - chemistry; Dose-Response Relationship, Drug; Dry Powder Inhalers; Guanidines; Healthy Volunteers; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Neuraminidase; Neuraminidase - antagonists & inhibitors; Pyrans; Sialic Acids; Viruses; Viruses - drug effects; Viruses - enzymology; Young Adult; Zanamivir; Zanamivir - administration & dosage; Zanamivir - adverse effects; Zanamivir - analogs & derivatives; Zanamivir - pharmacokinetics; influenza; inhalation; neuraminidase inhibitor; laninamivir; pharmacokinetics; intrapulmonary; bronchoalveolar lavage