Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody - Peng, Shiwen; Ferrall, Louise; Gaillard, Stephanie; Wang, Chenguang; Chi, Wei-Yu; Huang, Chuan-Hsiang; Roden, Richard B. S.; Wu, T.-C.; Chang, Yung-Nien; Hung, Chien-Fu (mBio, 2021)
Keywords: Animals; Antibodies, Monoclonal - administration & dosage; Bacterial Proteins - genetics; Bacterial Proteins - immunology; DNA-Binding Proteins - genetics; DNA-Binding Proteins - immunology; Female; HSP70 Heat-Shock Proteins - genetics; HSP70 Heat-Shock Proteins - immunology; Human papillomavirus 16 - drug effects; Human papillomavirus 16 - genetics; Human papillomavirus 16 - immunology; Human papillomavirus 18 - drug effects; Human papillomavirus 18 - genetics; Human papillomavirus 18 - immunology; Humans; Immunization, Secondary - methods; Mice; Mice, Inbred C57BL; Oncogene Proteins, Viral - genetics; Oncogene Proteins, Viral - immunology; Papillomavirus E7 Proteins - genetics; Papillomavirus E7 Proteins - immunology; Papillomavirus Infections - genetics; Papillomavirus Infections - immunology; Papillomavirus Infections - mortality; Papillomavirus Infections - prevention & control; Papillomavirus Vaccines - administration & dosage; Papillomavirus Vaccines - genetics; Papillomavirus Vaccines - immunology; Programmed Cell Death 1 Receptor - antagonists & inhibitors; Programmed Cell Death 1 Receptor - genetics; Programmed Cell Death 1 Receptor - immunology; Protein Engineering - methods; Recombinant Fusion Proteins - administration & dosage; Recombinant Fusion Proteins - genetics; Recombinant Fusion Proteins - immunology; Repressor Proteins - genetics; Repressor Proteins - immunology; Research Article; Survival Analysis; Therapeutics and Prevention; Uterine Cervical Neoplasms - genetics; Uterine Cervical Neoplasms - immunology; Uterine Cervical Neoplasms - mortality; Uterine Cervical Neoplasms - prevention & control; Vaccination - methods; Vaccines, DNA - administration & dosage; Vaccines, DNA - genetics; Vaccines, DNA - immunology; Vaccinia virus - chemistry; Vaccinia virus - immunology; DNA vaccine; E6; E7; human papillomavirus; HPV18; HPV-associated cancer; PD-1; TA-HPV; HPV16