Structure of the Plasmodium falciparum Triosephosphate Isomerase−Phosphoglycolate Complex in Two Crystal Forms: Characterization of Catalytic Loop Open and Closed Conformations in the Ligand-Bound State - Parthasarathy, S; Ravindra, G; Balaram, Hemalatha; Balaram, P; Murthy, M. R. N (Biochemistry (Easton), 2002)
Keywords: Amino Acid Substitution - genetics; Animals; Binding Sites - genetics; Catalysis; Crystallization; Crystallography, X-Ray; Dimerization; Enzyme Inhibitors - chemistry; Glyceric Acids - chemistry; Glycolates - chemistry; Ligands; Macromolecular Substances; Models, Molecular; Phenylalanine - chemistry; Phenylalanine - genetics; Plasmodium falciparum; Plasmodium falciparum - enzymology; Plasmodium falciparum - genetics; Protein Binding - genetics; Protein Conformation; Protein Structure, Tertiary - genetics; Triose-Phosphate Isomerase - antagonists & inhibitors; Triose-Phosphate Isomerase - chemistry; Triose-Phosphate Isomerase - genetics