Effect of Metformin on Left Ventricular Function After Acute Myocardial Infarction in Patients Without Diabetes: The GIPS-III Randomized Clinical Trial - Lexis, Chris P. H; van der Horst, Iwan C. C; Lipsic, Erik; Wieringa, Wouter G; de Boer, Rudolf A; van den Heuvel, Ad F. M; van der Werf, Hindrik W; Schurer, Remco A. J; Pundziute, Gabija; Tan, Eng S; Nieuwland, Wybe; Willemsen, Hendrik M; et al. (JAMA : the journal of the American Medical Association, 2014)
Keywords: Aged; Biological and medical sciences; Cardiology. Vascular system; Clinical outcomes; Coronary heart disease; Diabetes; Diabetes. Impaired glucose tolerance; Double-Blind Method; Drug therapy; Effectiveness studies; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; General aspects; Heart; Heart attacks; Humans; Hypoglycemic Agents - therapeutic use; Magnetic Resonance Imaging; Male; Medical sciences; Metformin - therapeutic use; Middle Aged; Myocardial Infarction - complications; Myocardial Infarction - drug therapy; Myocardial Infarction - physiopathology; Percutaneous Coronary Intervention; Treatment Outcome; Ventricular Dysfunction, Left - prevention & control; Ventricular Function, Left - drug effects; Endocrinopathy; Human; Myocardial infarction; Acute; Diabetes mellitus; Cardiovascular disease; Patient; Coronary heart disease; Myocardial disease; Medicine; Hypoglycemic agent; Biguanides; Gastrointestinal hormone; Clinical trial; Metformin; Left ventricle performance; Gastric inhibitory peptide