Antioxidative Effect of Lactic Acid Bacteria: Intact Cells vs. Intracellular Extracts

本研究比較兩株乳酸菌Bifidobacterium longum 和Lactobacillus delbrueckiisubsp. bulgaricus其菌體及胞內物的抗氧化能力。結果顯示，B. longum 和L.delbrueckii subsp. bulgaricus 在10^9 CFU/mL時，菌體及胞內物具有清除DPPH自由基能力(70.4-75.1%)、抑制liposome 過氧化(25-31%)以及顯著降低Intestine 407腸細胞脂質過氧化物(malondialdehyde, MDA)的生成。此外，本研究再進一步利用這兩株具有抗氧化能力乳酸菌的活菌體及其胞內物，探討對腦中...

Full description

Saved in:
Bibliographic Details
Published in藥物食品分析 Vol. 17; no. 3; pp. 209 - 216
Main Authors 歐珠琴(Chu-Chyn Ou), 呂聰明(Tsong-Ming Lu), 蔡肇基(Jaw-Ji Tsai), 顏志恒(Jyh-Herng Yen), 陳暉雯(Haw-Wen Chen), 林美吟(Meei-Yn Lin)
Format Journal Article
LanguageEnglish
Published 衛生福利部食品藥物管理署 01.06.2009
Subjects
LDL oxidation
菌體
抗氧化作用
antioxidation
lactic acid bacteria
低密度脂蛋白氧化作用
胞內物
intracellular extracts
乳酸菌
intact cells
Online AccessGet full text
ISSN1021-9498

Cover

Abstract 本研究比較兩株乳酸菌Bifidobacterium longum 和Lactobacillus delbrueckiisubsp. bulgaricus其菌體及胞內物的抗氧化能力。結果顯示，B. longum 和L.delbrueckii subsp. bulgaricus 在10^9 CFU/mL時，菌體及胞內物具有清除DPPH自由基能力(70.4-75.1%)、抑制liposome 過氧化(25-31%)以及顯著降低Intestine 407腸細胞脂質過氧化物(malondialdehyde, MDA)的生成。此外，本研究再進一步利用這兩株具有抗氧化能力乳酸菌的活菌體及其胞內物，探討對腦中風病人(cerebrovascular accident, CVA)和健康受試者血液中低密度脂蛋白(LDL)氧化作用的影響。LDL的氧化作用是以監測LDL conjugateddienes 形成的起始時間(lag time)爲指標。當B. longum和L. delbrueckii subsp. bulgaricus 以10^9 cfu/mL的菌數分別處理LDL時，LDL氧化作用的起始時間顯著被延長，健康受試者血液中LDL氧化被抑制效果優於CVA病人，而當以B. longum和L. delbrueckii subsp. bulgaricus 10^9 CFU/mL 菌數的胞內物處理CVA病人及健康受試者的LDL時，LDL氧化作用的起始時間顯著被延長超過180分鐘，此結果表示，抑制LDL氧化作用以乳酸菌的胞內物優於菌體。推論乳酸菌的胞內物具有效的抑制因子。
AbstractList 本研究比較兩株乳酸菌Bifidobacterium longum 和Lactobacillus delbrueckiisubsp. bulgaricus其菌體及胞內物的抗氧化能力。結果顯示，B. longum 和L.delbrueckii subsp. bulgaricus 在10^9 CFU/mL時，菌體及胞內物具有清除DPPH自由基能力(70.4-75.1%)、抑制liposome 過氧化(25-31%)以及顯著降低Intestine 407腸細胞脂質過氧化物(malondialdehyde, MDA)的生成。此外，本研究再進一步利用這兩株具有抗氧化能力乳酸菌的活菌體及其胞內物，探討對腦中風病人(cerebrovascular accident, CVA)和健康受試者血液中低密度脂蛋白(LDL)氧化作用的影響。LDL的氧化作用是以監測LDL conjugateddienes 形成的起始時間(lag time)爲指標。當B. longum和L. delbrueckii subsp. bulgaricus 以10^9 cfu/mL的菌數分別處理LDL時，LDL氧化作用的起始時間顯著被延長，健康受試者血液中LDL氧化被抑制效果優於CVA病人，而當以B. longum和L. delbrueckii subsp. bulgaricus 10^9 CFU/mL 菌數的胞內物處理CVA病人及健康受試者的LDL時，LDL氧化作用的起始時間顯著被延長超過180分鐘，此結果表示，抑制LDL氧化作用以乳酸菌的胞內物優於菌體。推論乳酸菌的胞內物具有效的抑制因子。
Author 陳暉雯(Haw-Wen Chen)
林美吟(Meei-Yn Lin)
呂聰明(Tsong-Ming Lu)
蔡肇基(Jaw-Ji Tsai)
歐珠琴(Chu-Chyn Ou)
顏志恒(Jyh-Herng Yen)
Author_xml – sequence: 1
  fullname: 歐珠琴(Chu-Chyn Ou)
– sequence: 2
  fullname: 呂聰明(Tsong-Ming Lu)
– sequence: 3
  fullname: 蔡肇基(Jaw-Ji Tsai)
– sequence: 4
  fullname: 顏志恒(Jyh-Herng Yen)
– sequence: 5
  fullname: 陳暉雯(Haw-Wen Chen)
– sequence: 6
  fullname: 林美吟(Meei-Yn Lin)
BookMark eNpdj8lqwzAURbVIoUnaf9APuDwN1tCda9wmYOimWRtFAygYGywl5PMrk666uue8xX3cHdpM8-Q3aEuAkkpzrZ7RLqULgKiZplt0aqYc53t0Jsebx10I3mY8B9wbm6PFjY0OfxT2SzTv-Djlwrj145jwLb2th8XYotfRLLi7r5bTC3oKZkz-9S_36PTZ_bSHqv_-OrZNXxlKIVfaOQmSBBaY42d2ro1ShbUmnNRAqK8tEUpaQrwMsgZvhRIAVCuuKROO7dHh0WviEnMcLvN1mcrDYZ27rh0ogAbxCFlKgZP_ogdKBPsFgQVTbg
ContentType Journal Article
DBID 188
DatabaseName Airiti Library
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
Discipline Diet & Clinical Nutrition
DocumentTitle_FL 乳酸菌之抗氧化作用：菌體與胞內物抗氧化能力之比較
EndPage 216
ExternalDocumentID 10219498_200906_200907150041_200907150041_209_216
GroupedDBID ---
0R~
0SF
188
2WC
3V.
53G
5GY
7RQ
7X2
7X7
88E
8FE
8FG
8FH
8FI
8FJ
A8Z
AACTN
AAHBH
AAWTL
ABDBF
ABFRF
ABJCF
ABUWG
ACGFO
ACGFS
ACIWK
AEFWE
AENEX
AFKRA
AFRAH
AHMBA
AIAGR
ALIPV
ALMA_UNASSIGNED_HOLDINGS
APEBS
ATCPS
BENPR
BGLVJ
BHPHI
BPHCQ
BVXVI
CCPQU
DIK
DWQXO
E3Z
EAD
EAP
EAS
EBD
EPL
ESTFP
ESX
FDB
FYUFA
GROUPED_DOAJ
HCIFZ
HMCUK
HZ~
L6V
LMWXZ
M0K
M1P
M7S
MK0
O9-
OK1
P2P
PC.
PQQKQ
PROAC
PSQYO
PTHSS
TR2
TUS
UKHRP
UNMZH
W2D
~8M
ID FETCH-LOGICAL-a220t-9dd7071f3f3d4b3b5a883f3991415012e5c1687c11e7f750ec6860029849236d3
ISSN 1021-9498
IngestDate Tue Oct 01 22:51:53 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 3
Keywords LDL oxidation
菌體
抗氧化作用
antioxidation
lactic acid bacteria
低密度脂蛋白氧化作用
胞內物
intracellular extracts
乳酸菌
intact cells
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-a220t-9dd7071f3f3d4b3b5a883f3991415012e5c1687c11e7f750ec6860029849236d3
PageCount 9
ParticipantIDs airiti_journals_10219498_200906_200907150041_200907150041_209_216
PublicationCentury 2000
PublicationDate 20090601
PublicationDateYYYYMMDD 2009-06-01
PublicationDate_xml – month: 06
  year: 2009
  text: 20090601
  day: 01
PublicationDecade 2000
PublicationTitle 藥物食品分析
PublicationTitle_FL Food and Drug Analysis
PublicationYear 2009
Publisher 衛生福利部食品藥物管理署
Publisher_xml – name: 衛生福利部食品藥物管理署
SSID ssj0065392
Score 1.929549
Snippet 本研究比較兩株乳酸菌Bifidobacterium longum 和Lactobacillus delbrueckiisubsp. bulgaricus其菌體及胞內物的抗氧化能力。結果顯示，B. longum 和L.delbrueckii subsp....
SourceID airiti
SourceType Publisher
StartPage 209
Title Antioxidative Effect of Lactic Acid Bacteria: Intact Cells vs. Intracellular Extracts
URI https://www.airitilibrary.com/Article/Detail/10219498-200906-200907150041-200907150041-209-216
Volume 17
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVEBS
  databaseName: EBSCO_Food Science Source
  issn: 1021-9498
  databaseCode: A8Z
  dateStart: 20080601
  customDbUrl:
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://search.ebscohost.com/login.aspx?authtype=ip,uid&profile=ehost&defaultdb=fsr
  omitProxy: false
  ssIdentifier: ssj0065392
  providerName: EBSCOhost
– providerCode: PRVEBS
  databaseName: EBSCOhost Academic Search Ultimate
  issn: 1021-9498
  databaseCode: ABDBF
  dateStart: 20080601
  customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn
  omitProxy: true
  ssIdentifier: ssj0065392
  providerName: EBSCOhost
– providerCode: PRVPQU
  databaseName: Health & Medical Collection
  issn: 1021-9498
  databaseCode: 7X7
  dateStart: 19960701
  customDbUrl:
  isFulltext: true
  dateEnd: 20200131
  titleUrlDefault: https://search.proquest.com/healthcomplete
  omitProxy: true
  ssIdentifier: ssj0065392
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Central
  issn: 1021-9498
  databaseCode: BENPR
  dateStart: 19960701
  customDbUrl: http://www.proquest.com/pqcentral?accountid=15518
  isFulltext: true
  dateEnd: 20200131
  titleUrlDefault: https://www.proquest.com/central
  omitProxy: true
  ssIdentifier: ssj0065392
  providerName: ProQuest
– providerCode: PRVPQU
  databaseName: ProQuest Technology Collection
  issn: 1021-9498
  databaseCode: 8FG
  dateStart: 19960701
  customDbUrl:
  isFulltext: true
  dateEnd: 99991231
  titleUrlDefault: https://search.proquest.com/technologycollection1
  omitProxy: true
  ssIdentifier: ssj0065392
  providerName: ProQuest
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9swDBaannYZ9sS6F3SYdglc-C1pNzlxkAVoBwwJkJ0CP-QlQOACibO1-_UjJSd1uh7WYRdbEkDKIj_bpB4kIR9k4Qa5iENwcvLICUsN38FSg6tSVZ5f5F7lazw7fHEZj2fhZB7NT3pfO7uWdk1-Xvy691zJv2gV2kCveEr2AZo9MIUGKIN-4Qoahutf6VjhVsXrVWmDd7eBiM2kP5586qtiVfYTG47ZpOD5XDd4JHKg1-tt_8f2HBs2Gc7dm82o6TXWbGinvcHKUsEkZypiKWdCMiVZCteAyRFLIyYDMEWxIAQTMUtjJlMmD0sg2KCG0GCoR0yZAlSTEFePlztnsLyp-192nQkJw9ZjwseugXniGrZQToFmCv7Bd-fCnM06poLnDJnyDJXPBDd8RixRQDXJfjqTVX-6xeTbHRqJBMKMJBnhOKEn6FL6SHOzdMZ6Ax19w0-zPJofkbf7uAyisVdgJRMzvtBIB6QWt8xBOlZwImBK3CfBP6UM1dSMxwgMhctZMmRJZ57WMztfQptg-_Cj4Z0XKuj-NVzZMUB8705s8NZZg38LMMS8odKN7Y2DOe-G3t2KXACPHukFHub04PPDFATGIbbr_-3jgd2VrTB6Vseomj4hj1tviCoL7afkRNfPyNlwpRv6kbYha9f0cp8x4jmZHUGeWsjTq4payFOEPN1D_hO1gKcG8BQAT48AT_eAf0Fmo3Q6GDttZhAn8323cWRZchhvFVRBGeZBHmVCQBl8HbBHweTSUeHFgheep3kFNrEuYmEWoAXGI4zL4CU5ra9q_YpQkYEBH2mRVbEfSjfIOPjY8P2SmczB88zOiLISWrQv_nbxYFW8_g883pBHt-h-S06bzU6_A3u4yd8bFf8GssSE4A
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Antioxidative+Effect+of+Lactic+Acid+Bacteria%3A+Intact+Cells+vs.+Intracellular+Extracts&rft.jtitle=%E8%97%A5%E7%89%A9%E9%A3%9F%E5%93%81%E5%88%86%E6%9E%90&rft.au=%E6%AD%90%E7%8F%A0%E7%90%B4%28Chu-Chyn+Ou%29&rft.au=%E5%91%82%E8%81%B0%E6%98%8E%28Tsong-Ming+Lu%29&rft.au=%E8%94%A1%E8%82%87%E5%9F%BA%28Jaw-Ji+Tsai%29&rft.au=%E9%A1%8F%E5%BF%97%E6%81%92%28Jyh-Herng+Yen%29&rft.date=2009-06-01&rft.pub=%E8%A1%9B%E7%94%9F%E7%A6%8F%E5%88%A9%E9%83%A8%E9%A3%9F%E5%93%81%E8%97%A5%E7%89%A9%E7%AE%A1%E7%90%86%E7%BD%B2&rft.issn=1021-9498&rft.volume=17&rft.issue=3&rft.spage=209&rft.epage=216&rft.externalDocID=10219498_200906_200907150041_200907150041_209_216
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fwww.airitilibrary.com%2Fjnltitledo%2F10219498-c.jpg