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A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug
Wallace, John L., Nagy, Peter, Feener, Troy D., Allain, Thibault, Ditrói, Tamás, Vaughan, David J., Muscara, Marcelo N., Nucci, Gilberto, Buret, Andre G.
Published in British journal of pharmacology (01.02.2020)
Published in British journal of pharmacology (01.02.2020)
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Journal Article
A Phase 2 clinical trial of PF-05212377 (SAM-760) in subjects with mild to moderate Alzheimer’s disease with existing neuropsychiatric symptoms on a stable daily dose of donepezil
Fullerton, Terence, Binneman, Brendon, David, William, Delnomdedieu, Marielle, Kupiec, James, Lockwood, Peter, Mancuso, Jessica, Miceli, Jeffrey, Bell, Joanne
Published in Alzheimer's research & therapy (05.04.2018)
Published in Alzheimer's research & therapy (05.04.2018)
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Journal Article
A randomized, double‐blind, multi‐center, placebo‐controlled, Phase 2 clinical trial to evaluate the efficacy and safety of DWJ211 in the treatment of moderate to severe submental fat
Paik, Seung Hwan, Jung, Joon Min, Jung, Chang Jin, Yang, Hee Joo, Son, Hyung Seok, Shin, Sun Hye, Yoo, Kwang Ho, Lee, Yang Won, Kim, Beom Joon, Won, Chong Hyun
Published in Dermatologic therapy (01.05.2022)
Published in Dermatologic therapy (01.05.2022)
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Journal Article
Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Undergoing Central Line Placement: A Phase 2 Clinical Trial
Pfeffer, Michael A., Kohs, Tia C.L., Vu, Helen H., Jordan, Kelley R., Wang, Jenny Si Han, Lorentz, Christina U., Tucker, Erik I., Puy, Cristina, Olson, Sven R., DeLoughery, Thomas G., Hinds, Monica T., Keshari, Ravi S., Gailani, David, Lupu, Florea, McCarty, Owen J.T., Shatzel, Joseph J.
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2024)
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Journal Article
A phase 2 clinical trial of adjuvant ado-trastuzumab emtansine (T-DM1) for patients with HER2-positive salivary gland cancer
Hanna, Glenn J., Shi, Ruichao, Liao, Jay Justin, Pearson, Alexander T., Rosenberg, Ari Joseph, Ho, Alan Loh, Rettig, Eleni M., Tishler, Roy B., Sethi, Rosh K., Annino, Donald J., Goguen, Laura A, Sehgal, Kartik, Dennis, Michael J., Jo, Vickie Y., Wong, Kristine S., Steuer, Conor Ernst, Uppaluri, Ravindra, Schoenfeld, Jonathan Daniel, Haddad, Robert I., Margalit, Danielle N
Published in Journal of clinical oncology (01.06.2025)
Published in Journal of clinical oncology (01.06.2025)
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Journal Article
Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer’s disease, positive for plasma p-tau217
Kovacech, Branislav, Cullen, Nicholas C., Novak, Petr, Hanes, Jozef, Kontsekova, Eva, Katina, Stanislav, Parrak, Vojtech, Fresser, Michal, Vanbrabant, Jeroen, Feldman, Howard H., Winblad, Bengt, Stoops, Erik, Vanmechelen, Eugeen, Zilka, Norbert
Published in Alzheimer's research & therapy (23.11.2024)
Published in Alzheimer's research & therapy (23.11.2024)
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Journal Article
Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis
Elborn, J. Stuart, Konstan, Michael W., Taylor-Cousar, Jennifer L., Fajac, Isabelle, Horsley, Alexander, Sutharsan, Sivagurunathan, Aaron, Shawn D., Daines, Cori L., Uluer, Ahmet, Downey, Damian G., Lucidi, Vincenzina V., Ahuja, Sanjeev, Springman, Eric, Mershon, John, Grosswald, Ralph, Rowe, Steven M.
Published in Journal of cystic fibrosis (01.11.2021)
Published in Journal of cystic fibrosis (01.11.2021)
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Journal Article
Iron-based biomarkers for personalizing pharmacological ascorbate therapy in glioblastoma: insights from a phase 2 clinical trial
Petronek, M. S., Bodeker, K. L., Lee, C. Y., Teferi, N., Eschbacher, K. L., Jones, K. A., Loeffler, B. T., Smith, B. J., Buatti, J. M., Magnotta, V. A., Allen, B. G.
Published in Journal of neuro-oncology (01.02.2024)
Published in Journal of neuro-oncology (01.02.2024)
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Journal Article
An Exploratory, Phase 2 Clinical Trial In Knee Osteoarthritis Subjects Suggests Therapeutic Effects Of Pentosan Polysulfate Sodium On Synovial Fluid Biomarkers Of Pain, Inflammation And Chondroprotection
Ahuja, M., Duiker, M., Gravance, C., Navuru, D., Krishnan, R., Skerrett, D., Cumming, O., Bloom, P.
Published in Osteoarthritis and cartilage (01.03.2023)
Published in Osteoarthritis and cartilage (01.03.2023)
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Journal Article
33323 Dersimelagon, a melanocortin-1 receptor agonist, maintains efficacy regardless of seasons in subjects with erythropoietic protoporphyria: Results from a post hoc analysis of phase 2 clinical trial data
Belongie, Kirstine, Takahashi, Fumihiro, Mukai, Sakiko, Endou, Mai, Desnick, Robert
Published in Journal of the American Academy of Dermatology (01.09.2022)
Published in Journal of the American Academy of Dermatology (01.09.2022)
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Journal Article
Designing a single-arm phase 2 clinical trial of mitapivat for adult patients with erythrocyte membranopathies (SATISFY): a framework for interventional trials in rare anaemias – pilot study protocol
Glenthøj, Andreas, van Beers, Eduard J, van Wijk, Richard, Rab, Minke A E, Groot, Evelyn, Vejlstrup, Niels, Toft, Nina, Bendtsen, Selma Kofoed, Petersen, Jesper, Helby, Jens, Chermat, Fatiha, Fenaux, Pierre, Kuo, Kevin H M
Published in BMJ open (30.07.2024)
Published in BMJ open (30.07.2024)
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Journal Article
Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus Candida adjuvant alone in treating cervical intraepithelial neoplasia 2/3
Evans, Teresa, Bimali, Milan, Coleman, Hannah, Crane, Jasmine, Darwish, Nadia, Lu, Yong-Chen, Nookaew, Intawat, Marsh, Keanna, Robeson, Michael Scott, Shibata, Takeo, Ussery, David, Greenfield, William
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Evaluating Digital Twins for Alzheimer’s Disease using Data from a Completed Phase 2 Clinical Trial
Walsh, Jonathan R., Roumpanis, Spyros, Bertolini, Daniele, Delmar, Paul
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Use of a Novel Artificial Intelligence Platform on Mobile Devices to Assess Dosing Compliance in a Phase 2 Clinical Trial in Subjects With Schizophrenia
Bain, Earle E, Shafner, Laura, Walling, David P, Othman, Ahmed A, Chuang-Stein, Christy, Hinkle, John, Hanina, Adam
Published in JMIR mHealth and uHealth (21.02.2017)
Published in JMIR mHealth and uHealth (21.02.2017)
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Journal Article
Effect of denosumab on bone mineral density and biochemical markers of bone turnover: 8-year results of a phase 2 clinical trial
McClung, M. R., Lewiecki, E. M., Geller, M. L., Bolognese, M. A., Peacock, M., Weinstein, R. L., Ding, B., Rockabrand, E., Wagman, R. B., Miller, P. D.
Published in Osteoporosis international (01.01.2013)
Published in Osteoporosis international (01.01.2013)
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Journal Article
Rift Valley fever MP-12 vaccine Phase 2 clinical trial: Safety, immunogenicity, and genetic characterization of virus isolates
Pittman, Phillip R., Norris, Sarah L., Brown, Elizabeth S., Ranadive, Manmohan V., Schibly, Barbara A., Bettinger, George E., Lokugamage, Nandadeva, Korman, Lawrence, Morrill, John C., Peters, Clarence J.
Published in Vaccine (20.01.2016)
Published in Vaccine (20.01.2016)
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Journal Article
Oral tablet vaccination against SARS-CoV-2 spike boosts cross-reactive serum and mucosal neutralizing antibodies following mRNA vaccination: a phase 2 clinical trial
johnson, susan, Jegede, Clara B, Gutierrez, Samanta, Greco, Susan, Cummings, James, Gottlieb, Keith A, Tucker, Sean N
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Immunogenicity and safety of an enterovirus 71 vaccine in healthy Chinese children and infants: a randomised, double-blind, placebo-controlled phase 2 clinical trial
Zhu, Feng-Cai, Liang, Zheng-Lun, Li, Xiu-Ling, Ge, Heng-Ming, Meng, Fan-Yue, Mao, Qun-Ying, Zhang, Yun-Tao, Hu, Yue-Mei, Zhang, Zhen-Yu, Li, Jing-Xin, Gao, Fan, Chen, Qing-Hua, Zhu, Qi-Yan, Chu, Kai, Wu, Xing, Yao, Xin, Guo, Hui-Jie, Chen, Xiao-Qin, Liu, Pei, Dong, Yu-Ying, Li, Feng-Xiang, Shen, Xin-Liang, Wang, Jun-Zhi
Published in The Lancet (British edition) (23.03.2013)
Published in The Lancet (British edition) (23.03.2013)
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Journal Article
The Design and Rationale of the Trail1 Trial: A Randomized Double-Blind Phase 2 Clinical Trial of Pirfenidone in Rheumatoid Arthritis-Associated Interstitial Lung Disease
Solomon, Joshua J., Danoff, Sonye K., Goldberg, Hilary J., Woodhead, Felix, Kolb, Martin, Chambers, Daniel C., DiFranco, Donna, Spino, Cathy, Haynes-Harp, Shana, Hurwitz, Shelley, Peters, Elizabeth B., Dellaripa, Paul F., Rosas, Ivan O.
Published in Advances in therapy (01.11.2019)
Published in Advances in therapy (01.11.2019)
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Journal Article