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Randomized Trial of Macitentan/Tadalafil Single-Tablet Combination Therapy for Pulmonary Arterial Hypertension
Grünig, Ekkehard, Jansa, Pavel, Fan, Fenling, Hauser, Jakob A., Pannaux, Matthieu, Morganti, Adele, Rofael, Hany, Chin, Kelly M.
Published in Journal of the American College of Cardiology (30.01.2024)
Published in Journal of the American College of Cardiology (30.01.2024)
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Journal Article
Bioequivalence of macitentan and tadalafil given as fixed‐dose combination or single‐component tablets in healthy subjects
Grill, Simon, Bruderer, Shirin, Sidharta, Patricia N., Antonova, Mariya, Globig, Susanne, Carlson, James, Schultz, Armin, Csonka, Dénes
Published in British journal of clinical pharmacology (01.12.2020)
Published in British journal of clinical pharmacology (01.12.2020)
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Journal Article
Macitentan in the Young—Mid-term Outcomes of Patients with Pulmonary Hypertensive Vascular Disease treated in a Pediatric Tertiary Care Center
Albinni, Sulaima, Heno, Julian, Pavo, Imre, Kitzmueller, Erwin, Marx, Manfred, Michel-Behnke, Ina
Published in Paediatric drugs (01.07.2023)
Published in Paediatric drugs (01.07.2023)
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Journal Article
Bioequivalence and the food effect of macitentan/tadalafil 10/20 fixed‐dose combination tablets versus the use of single‐component tablets in healthy subjects
Ford, Jennifer Lynn, Sabet, Ahad, Natarajan, Jaya, Stieltjes, Hans, Chao, Daniel L., Goyal, Navin, Csonka, Denes
Published in Pharmacology research & perspectives (01.06.2024)
Published in Pharmacology research & perspectives (01.06.2024)
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Journal Article
Macitentan Does Not Interfere with Hepatic Bile Salt Transport
Treiber, Alexander, Äänismaa, Päivi, de Kanter, Ruben, Delahaye, Stephane, Treher, Marianne, Hess, Patrick, Sidharta, Patricia
Published in The Journal of pharmacology and experimental therapeutics (01.07.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2014)
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Journal Article
Investigation of the Effects of Ketoconazole on the Pharmacokinetics of Macitentan, a Novel Dual Endothelin Receptor Antagonist, in Healthy Subjects
Atsmon, Jacob, Dingemanse, Jasper, Shaikevich, Dimitri, Volokhov, Inna, Sidharta, Patricia N.
Published in Clinical pharmacokinetics (01.08.2013)
Published in Clinical pharmacokinetics (01.08.2013)
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Journal Article
Effects of Dual Initial Combination Therapy With Macitentan Plus Riociguat or Macitentan Plus Selexipag on Hemodynamics in Patients With Pulmonary Arterial Hypertension (SETOUCHI-PH Study) ― Protocol of a Multicenter Randomized Control Trial
Nakamura, Kazufumi, Kubota, Kayoko, Ito, Hiroshi, Yagi, Shusuke, Horimoto, Koshin, Hirata, Tetsuo, Yamamoto, Eiichiro, Akagi, Satoshi, Dohi, Yoshihiro, Ishikawa, Kaori
Published in Circulation Reports (10.02.2021)
Published in Circulation Reports (10.02.2021)
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Journal Article
Pharmacological counseling in hepatotoxicity induced by macitentan and selexipag: a case report
Lattanzio, Mariangela, Ferrari, Marco, Martini, Stefano, Ceriani, Francesca, Imporzani, Andrea, Marino, Franca, De Ponti, Roberto, Cosentino, Marco
Published in Journal of medical case reports (18.10.2022)
Published in Journal of medical case reports (18.10.2022)
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Journal Article
Macitentan: A Review in Pulmonary Arterial Hypertension
Keating, Gillian M.
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01.12.2016)
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01.12.2016)
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Journal Article
A Population Pharmacokinetic Model of Macitentan and Its Active Metabolite Aprocitentan in Healthy Volunteers and Patients with Pulmonary Arterial Hypertension
Bartolucci, Roberta, Dosne, Anne-Gaëlle, Csonka, Dénes, Pérez-Ruixo, Juan José, Magni, Paolo, Poggesi, Italo
Published in Clinical pharmacokinetics (01.12.2021)
Published in Clinical pharmacokinetics (01.12.2021)
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Journal Article
Investigation of mutual pharmacokinetic interactions between macitentan, a novel endothelin receptor antagonist, and sildenafil in healthy subjects
Sidharta, Patricia N., Giersbergen, Paul L. M., Wolzt, Michael, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.11.2014)
Published in British journal of clinical pharmacology (01.11.2014)
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Journal Article
Effect of Macitentan on the Pharmacokinetics of the Breast Cancer Resistance Protein Substrates, Rosuvastatin and Riociguat, in Healthy Male Subjects
Csonka, Dénes, Bruderer, Shirin, Schultz, Armin, Soergel, Marianne, Stepanova, Radka, Sabattini, Giancarlo, Perez-Ruixo, Juan Jose
Published in Clinical drug investigation (01.12.2019)
Published in Clinical drug investigation (01.12.2019)
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Journal Article
Pharmacokinetics of Macitentan in Caucasian and Japanese Subjects: The Influence of Ethnicity and Sex
Bruderer, Shirin, Marjason, Joanne, Sidharta, Patricia N., Dingemanse, Jasper
Published in Pharmacology (01.01.2013)
Published in Pharmacology (01.01.2013)
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Journal Article
Bioequivalence and food effect of a fixed‐dose combination of macitentan and tadalafil: Adaptive design in the COVID‐19 pandemic
Csonka, Dénes, Fishman, Vladislav, Natarajan, Jaya, Stieltjes, Hans, Armas, Danielle, Dishy, Victor, Perez Ruixo, Juan Jose
Published in Pharmacology research & perspectives (01.10.2021)
Published in Pharmacology research & perspectives (01.10.2021)
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Journal Article
Effect of Cyclosporine and Rifampin on the Pharmacokinetics of Macitentan, a Tissue-Targeting Dual Endothelin Receptor Antagonist
Bruderer, Shirin, Äänismaa, Päivi, Homery, Marie-Claude, Häusler, Stephanie, Landskroner, Kyle, Sidharta, Patricia N., Treiber, Alexander, Dingemanse, Jasper
Published in The AAPS journal (01.03.2012)
Published in The AAPS journal (01.03.2012)
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Journal Article
Absorption, distribution, metabolism, and excretion of macitentan, a dual endothelin receptor antagonist, in humans
Bruderer, Shirin, Hopfgartner, Gérard, Seiberling, Michael, Wank, Janine, Sidharta, Patricia N., Treiber, Alexander, Dingemanse, Jasper
Published in Xenobiotica (01.09.2012)
Published in Xenobiotica (01.09.2012)
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Journal Article
Pharmacokinetic–Pharmacodynamic Relationships of Macitentan, a New Endothelin Receptor Antagonist, After Multiple Dosing in Healthy Korean Subjects
Ahn, Li Young, Kim, Sung Eun, Yi, SoJeong, Dingemanse, Jasper, Lim, Kyoung Soo, Jang, In-Jin, Yu, Kyung-Sang
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01.10.2014)
Published in American journal of cardiovascular drugs : drugs, devices, and other interventions (01.10.2014)
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Journal Article