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A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin
Sullivan-Bólyai, John Z, Allen, Larry B, Cannon, Rebecca, Cohane, Kenya P, Dunzo, Elise, Goldwater, Ronald, StCyr, Kathleen, Wang, Yang, Klempner, Mark S
Published in The Journal of infectious diseases (21.11.2024)
Published in The Journal of infectious diseases (21.11.2024)
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Journal Article
A cross-reacting material CRM197 conjugate vaccine induces diphtheria toxin neutralizing antibody response in children and adolescents infected or not with HIV
Silva, Giselle P., Santos, Rafaela S., Pereira-Manfro, Wânia F., Ferreira, Bianca, Barreto, Daniella M., Frota, Ana Cristina C., Hofer, Cristina B., Milagres, Lucimar G.
Published in Vaccine (05.07.2017)
Published in Vaccine (05.07.2017)
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Journal Article
A cross-reacting material CRM197conjugate vaccine induces diphtheria toxin neutralizing antibody response in children and adolescents infected or not with HIV
Silva, Giselle P, Santos, Rafaela S, Pereira-Manfro, Wânia F, Ferreira, Bianca, Barreto, Daniella M, Frota, Ana Cristina C, Hofer, Cristina B, Milagres, Lucimar G
Published in Vaccine (05.07.2017)
Published in Vaccine (05.07.2017)
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Journal Article
CRM197 (nontoxic diphtheria toxin): effects on advanced cancer patients
Buzzi, Silvio, Rubboli, Diego, Buzzi, Giorgio, Buzzi, AnnaMaria, Morisi, Claudio, Pironi, Flavio
Published in Cancer Immunology, Immunotherapy (01.11.2004)
Published in Cancer Immunology, Immunotherapy (01.11.2004)
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Journal Article
Phase I Study of a Bispecific Ligand-Directed Toxin Targeting CD22 and CD19 (DT2219) for Refractory B-cell Malignancies
Bachanova, Veronika, Frankel, Arthur E., Cao, Qing, Lewis, Dixie, Grzywacz, Bartosz, Verneris, Michael R., Ustun, Celalettin, Lazaryan, Aleksandr, McClune, Brian, Warlick, Erica D., Kantarjian, Hagop, Weisdorf, Daniel J., Miller, Jeffrey S., Vallera, Daniel A.
Published in Clinical cancer research (15.03.2015)
Published in Clinical cancer research (15.03.2015)
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Journal Article
Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer
Hanna, N, Ohana, P, Konikoff, F M, Leichtmann, G, Hubert, A, Appelbaum, L, Kopelman, Y, Czerniak, A, Hochberg, A
Published in Cancer gene therapy (01.06.2012)
Published in Cancer gene therapy (01.06.2012)
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Journal Article
Determination of the Presence of Diphtheria Toxin in the Myocardial Tissue of Rabbits and a Female Subject by Using an Immunofluorescent Antibody Method
Ceyhan, Mehmet, Ozsurekci, Yasemin, Aydin, Merve M., Akcali, Kamil Can, Talim, Beril, Celik, Melda, Karadag Oncel, Eda, Gurbuz, Venhar, Aycan, Ahmet Emre, Onbasilar, Ilyas, Buzgan, Turan
Published in Journal of clinical medicine research (01.06.2015)
Published in Journal of clinical medicine research (01.06.2015)
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Journal Article
Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis
Hammarlund, Erika, Thomas, Archana, Poore, Elizabeth A., Amanna, Ian J., Rynko, Abby E., Mori, Motomi, Chen, Zunqiu, Slifka, Mark K.
Published in Clinical infectious diseases (01.05.2016)
Published in Clinical infectious diseases (01.05.2016)
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Journal Article
A cross-reacting material CRM 197 conjugate vaccine induces diphtheria toxin neutralizing antibody response in children and adolescents infected or not with HIV
Silva, Giselle P, Santos, Rafaela S, Pereira-Manfro, Wânia F, Ferreira, Bianca, Barreto, Daniella M, Frota, Ana Cristina C, Hofer, Cristina B, Milagres, Lucimar G
Published in Vaccine (05.07.2017)
Published in Vaccine (05.07.2017)
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Journal Article
A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer
Lavie, Ofer, Edelman, David, Levy, Tally, Fishman, Ami, Hubert, Ayala, Segev, Yakir, Raveh, Eli, Gilon, Michal, Hochberg, Avraham
Published in Archives of gynecology and obstetrics (01.03.2017)
Published in Archives of gynecology and obstetrics (01.03.2017)
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Journal Article
Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2
Birey, Fikri, Kloc, Michelle, Chavali, Manideep, Hussein, Israa, Wilson, Michael, Christoffel, Daniel J., Chen, Tony, Frohman, Michael A., Robinson, John K., Russo, Scott J., Maffei, Arianna, Aguirre, Adan
Published in Neuron (Cambridge, Mass.) (02.12.2015)
Published in Neuron (Cambridge, Mass.) (02.12.2015)
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Journal Article
Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia
Puñal, Vanessa M., Paisley, Caitlin E., Brecha, Federica S., Lee, Monica A., Perelli, Robin M., Wang, Jingjing, O’Koren, Emily G., Ackley, Caroline R., Saban, Daniel R., Reese, Benjamin E., Kay, Jeremy N.
Published in PLoS biology (18.10.2019)
Published in PLoS biology (18.10.2019)
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Journal Article
Percutaneous sensitization is limited by in situ inhibition of cutaneous dendritic cell migration through skin-resident regulatory T cells
Hanakawa, Sho, Kitoh, Akihiko, Shibuya, Rintaro, Dainichi, Teruki, Nomura, Takashi, Honda, Tetsuya, Egawa, Gyohei, Otsuka, Atsushi, Nakajima, Saeko, Fujita, Mitsugu, Kabashima, Kenji
Published in Journal of allergy and clinical immunology (01.11.2019)
Published in Journal of allergy and clinical immunology (01.11.2019)
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Journal Article
Corynebacterium species nasopharyngeal carriage in asymptomatic individuals aged ≥ 65 years in Germany
Teutsch, Barbara, Berger, Anja, Marosevic, Durdica, Schönberger, Katharina, Lâm, Thiên-Trí, Hubert, Kerstin, Beer, Steffi, Wienert, Peter, Ackermann, Nikolaus, Claus, Heike, Drayß, Maria, Thiel, Kathrin, van der Linden, Mark, Vogel, Ulrich, Sing, Andreas
Published in Infection (01.10.2017)
Published in Infection (01.10.2017)
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Journal Article
Mitigating Age-Related Immune Dysfunction Heightens the Efficacy of Tumor Immunotherapy in Aged Mice
Hurez, Vincent, Daniel, Benjamin J., Sun, Lishi, Liu, Ai-Jie, Ludwig, Sara M., Kious, Mark J., Thibodeaux, Suzanne R., Pandeswara, Srilakshmi, Murthy, Kruthi, Livi, Carolina B., Wall, Shawna, Brumlik, Michael J., Shin, Tahiro, Zhang, Bin, Curiel, Tyler J.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells
Bachanova, Veronika, Cooley, Sarah, Defor, Todd, Verneris, Michael R, Zhang, Bin, McKenna, David, Curtsinger, Julie, Panoskaltsis-Mortari, Angela, Lewis, Dixie, Hippen, Keli, McGlave, Philip, Weisdorf, Daniel, Blazar, Bruce R, Miller, Jeffrey S
Published in Journal for immunotherapy of cancer (07.11.2013)
Published in Journal for immunotherapy of cancer (07.11.2013)
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Journal Article
Phase II trial of the regulatory T cell-depleting agent, denileukin diftitox, in patients with unresectable stage IV melanoma
Telang, Sucheta, Rasku, Mary Ann, Clem, Amy L, Carter, Karen, Klarer, Alden C, Badger, Wesley R, Milam, Rebecca A, Rai, Shesh N, Pan, Jianmin, Gragg, Hana, Clem, Brian F, McMasters, Kelly M, Miller, Donald M, Chesney, Jason
Published in BMC cancer (13.12.2011)
Published in BMC cancer (13.12.2011)
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Journal Article
Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis
Wilke, Justus B. H., Hindermann, Martin, Moussavi, Amir, Butt, Umer Javed, Dadarwal, Rakshit, Berghoff, Stefan A., Sarcheshmeh, Aref Kalantari, Ronnenberg, Anja, Zihsler, Svenja, Arinrad, Sahab, Hardeland, Rüdiger, Seidel, Jan, Lühder, Fred, Nave, Klaus-Armin, Boretius, Susann, Ehrenreich, Hannelore
Published in Acta neuropathologica communications (02.07.2021)
Published in Acta neuropathologica communications (02.07.2021)
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Journal Article