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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon E., Vaughan, Spencer W., Lorenzini, Ileana, Liu, Feilin, Sayegh, Melissa, Donlin-Asp, Paul G., Chen, Yu Han, Duong, Duc M., Seyfried, Nicholas T., Powers, Maureen A., Kukar, Thomas, Hales, Chadwick M., Gearing, Marla, Cairns, Nigel J., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa, Zhang, Yong-Jie, Petrucelli, Leonard, Sattler, Rita, Zarnescu, Daniela C., Glass, Jonathan D., Rossoll, Wilfried
Published in Nature neuroscience (01.02.2018)
Published in Nature neuroscience (01.02.2018)
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Journal Article
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
Yong-Jie, Zhang, Gendron, Tania F, Ebbert, Mark T W, Aliesha D O’Raw, Yue, Mei, Jansen-West, Karen, Zhang, Xu, Prudencio, Mercedes, Chew, Jeannie, Cook, Casey N, Daughrity, Lillian M, Tong, Jimei, Song, Yuping, Pickles, Sarah R, Castanedes-Casey, Monica, Kurti, Aishe, Rademakers, Rosa, Oskarsson, Bjorn, Dickson, Dennis W, Hu, Wenqian, Gitler, Aaron D, Fryer, John D, Petrucelli, Leonard
Published in Nature medicine (01.08.2018)
Published in Nature medicine (01.08.2018)
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Journal Article
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
Liu-Yesucevitz, Liqun, Bilgutay, Aylin, Zhang, Yong-Jie, Vanderwyde, Tara, Citro, Allison, Mehta, Tapan, Zaarur, Nava, McKee, Ann, Bowser, Robert, Sherman, Michael, Petrucelli, Leonard, Wolozin, Benjamin
Published in PloS one (11.10.2010)
Published in PloS one (11.10.2010)
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Journal Article
Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration
Shao, Wei, Todd, Tiffany W., Wu, Yanwei, Jones, Caroline Y., Tong, Jimei, Jansen-West, Karen, Daughrity, Lillian M., Park, Jinyoung, Koike, Yuka, Kurti, Aishe, Yue, Mei, Castanedes-Casey, Monica, del Rosso, Giulia, Dunmore, Judith A., Zanetti Alepuz, Desiree, Oskarsson, Björn, Dickson, Dennis W., Cook, Casey N., Prudencio, Mercedes, Gendron, Tania F., Fryer, John D., Zhang, Yong-Jie, Petrucelli, Leonard
Published in Science (American Association for the Advancement of Science) (07.10.2022)
Published in Science (American Association for the Advancement of Science) (07.10.2022)
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Journal Article
Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial
Chen, Fa-Ming, Gao, Li-Na, Tian, Bei-Min, Zhang, Xi-Yu, Zhang, Yong-Jie, Dong, Guang-Ying, Lu, Hong, Chu, Qing, Xu, Jie, Yu, Yang, Wu, Rui-Xin, Yin, Yuan, Shi, Songtao, Jin, Yan
Published in Stem cell research & therapy (19.02.2016)
Published in Stem cell research & therapy (19.02.2016)
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Journal Article
C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
Chew, Jeannie, Gendron, Tania F., Prudencio, Mercedes, Sasaguri, Hiroki, Zhang, Yong-Jie, Castanedes-Casey, Monica, Lee, Chris W., Jansen-West, Karen, Kurti, Aishe, Murray, Melissa E., Bieniek, Kevin F., Bauer, Peter O., Whitelaw, Ena C., Rousseau, Linda, Stankowski, Jeannette N., Stetler, Caroline, Daughrity, Lillian M., Perkerson, Emilie A., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Edbauer, Dieter, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Fryer, John D., Petrucelli, Leonard
Published in Science (American Association for the Advancement of Science) (05.06.2015)
Published in Science (American Association for the Advancement of Science) (05.06.2015)
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Journal Article
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
Chew, Jeannie, Cook, Casey, Gendron, Tania F., Jansen-West, Karen, del Rosso, Giulia, Daughrity, Lillian M., Castanedes-Casey, Monica, Kurti, Aishe, Stankowski, Jeannette N., Disney, Matthew D., Rothstein, Jeffrey D., Dickson, Dennis W., Fryer, John D., Zhang, Yong-Jie, Petrucelli, Leonard
Published in Molecular neurodegeneration (15.02.2019)
Published in Molecular neurodegeneration (15.02.2019)
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Journal Article
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
Zhang, Yong-Jie, Guo, Lin, Gonzales, Patrick K., Gendron, Tania F., Wu, Yanwei, Jansen-West, Karen, O’Raw, Aliesha D., Pickles, Sarah R., Prudencio, Mercedes, Carlomagno, Yari, Gachechiladze, Mariam A., Ludwig, Connor, Tian, Ruilin, Chew, Jeannie, DeTure, Michael, Lin, Wen-Lang, Tong, Jimei, Daughrity, Lillian M., Yue, Mei, Song, Yuping, Andersen, Jonathan W., Castanedes-Casey, Monica, Kurti, Aishe, Datta, Abhishek, Antognetti, Giovanna, McCampbell, Alexander, Rademakers, Rosa, Oskarsson, Björn, Dickson, Dennis W., Kampmann, Martin, Ward, Michael E., Fryer, John D., Link, Christopher D., Shorter, James, Petrucelli, Leonard
Published in Science (American Association for the Advancement of Science) (15.02.2019)
Published in Science (American Association for the Advancement of Science) (15.02.2019)
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Journal Article
TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A
Koike, Yuka, Pickles, Sarah, Estades Ayuso, Virginia, Jansen-West, Karen, Qi, Yue A., Li, Ziyi, Daughrity, Lillian M., Yue, Mei, Zhang, Yong-Jie, Cook, Casey N., Dickson, Dennis W., Ward, Michael, Petrucelli, Leonard, Prudencio, Mercedes
Published in PLoS biology (17.03.2023)
Published in PLoS biology (17.03.2023)
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Journal Article
The effect of aging on the pluripotential capacity and regenerative potential of human periodontal ligament stem cells
Zhang, Jing, An, Ying, Gao, Li-Na, Zhang, Yong-Jie, Jin, Yan, Chen, Fa-Ming
Published in Biomaterials (01.10.2012)
Published in Biomaterials (01.10.2012)
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Journal Article
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS
Gendron, Tania F., Bieniek, Kevin F., Zhang, Yong-Jie, Jansen-West, Karen, Ash, Peter E. A., Caulfield, Thomas, Daughrity, Lillian, Dunmore, Judith H., Castanedes-Casey, Monica, Chew, Jeannie, Cosio, Danielle M., van Blitterswijk, Marka, Lee, Wing C., Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Published in Acta neuropathologica (01.12.2013)
Published in Acta neuropathologica (01.12.2013)
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Journal Article
Genomic analyses reveal low mitochondrial and high nuclear diversity in the cyclosporin-producing fungus Tolypocladium inflatum
Zhang, Yong-Jie, Yang, Xiao-Qing, Zhang, Shu, Humber, Richard A., Xu, Jianping
Published in Applied microbiology and biotechnology (01.12.2017)
Published in Applied microbiology and biotechnology (01.12.2017)
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Journal Article
Dynamic evolution of eukaryotic mitochondrial and nuclear genomes: a case study in the gourmet pine mushroom Tricholoma matsutake
Zhang, Shu, Bai, Xue, Ren, Li‐Yuan, Sun, Hui‐Hui, Tang, Hui‐Ping, Vaario, Lu‐Min, Xu, Jianping, Zhang, Yong‐Jie
Published in Environmental microbiology (01.11.2021)
Published in Environmental microbiology (01.11.2021)
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Journal Article
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Published in Acta neuropathologica (01.10.2014)
Published in Acta neuropathologica (01.10.2014)
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Journal Article