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Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning
Alipanahi, Babak, Delong, Andrew, Weirauch, Matthew T, Frey, Brendan J
Published in Nature biotechnology (01.08.2015)
Published in Nature biotechnology (01.08.2015)
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Journal Article
Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers
Petrany, Michael J., Swoboda, Casey O., Sun, Chengyi, Chetal, Kashish, Chen, Xiaoting, Weirauch, Matthew T., Salomonis, Nathan, Millay, Douglas P.
Published in Nature communications (11.12.2020)
Published in Nature communications (11.12.2020)
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Journal Article
Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity
Weirauch, Matthew T., Yang, Ally, Albu, Mihai, Cote, Atina G., Montenegro-Montero, Alejandro, Drewe, Philipp, Najafabadi, Hamed S., Lambert, Samuel A., Mann, Ishminder, Cook, Kate, Zheng, Hong, Goity, Alejandra, van Bakel, Harm, Lozano, Jean-Claude, Galli, Mary, Lewsey, Mathew G., Huang, Eryong, Mukherjee, Tuhin, Chen, Xiaoting, Reece-Hoyes, John S., Govindarajan, Sridhar, Shaulsky, Gad, Walhout, Albertha J.M., Bouget, François-Yves, Ratsch, Gunnar, Larrondo, Luis F., Ecker, Joseph R., Hughes, Timothy R.
Published in Cell (11.09.2014)
Published in Cell (11.09.2014)
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Journal Article
PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease
Moreno-Fernandez, Maria E., Giles, Daniel A., Oates, Jarren R., Chan, Calvin C., Damen, Michelle S.M.A., Doll, Jessica R., Stankiewicz, Traci E., Chen, Xiaoting, Chetal, Kashish, Karns, Rebekah, Weirauch, Matthew T., Romick-Rosendale, Lindsey, Xanthakos, Stavra A., Sheridan, Rachel, Szabo, Sara, Shah, Amy S., Helmrath, Michael A., Inge, Thomas H., Deshmukh, Hitesh, Salomonis, Nathan, Divanovic, Senad
Published in Cell metabolism (01.06.2021)
Published in Cell metabolism (01.06.2021)
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Journal Article
C2H2 zinc finger proteins greatly expand the human regulatory lexicon
Najafabadi, Hamed S, Mnaimneh, Sanie, Schmitges, Frank W, Garton, Michael, Lam, Kathy N, Yang, Ally, Albu, Mihai, Weirauch, Matthew T, Radovani, Ernest, Kim, Philip M, Greenblatt, Jack, Frey, Brendan J, Hughes, Timothy R
Published in Nature biotechnology (01.05.2015)
Published in Nature biotechnology (01.05.2015)
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Journal Article
Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?
Korinfskaya, Svetlana, Parameswaran, Sreeja, Weirauch, Matthew T., Barski, Artem
Published in Frontiers in immunology (06.08.2021)
Published in Frontiers in immunology (06.08.2021)
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Journal Article
NOMe-HiC: joint profiling of genetic variant, DNA methylation, chromatin accessibility, and 3D genome in the same DNA molecule
Fu, Hailu, Zheng, Haizi, Chen, Xiaoting, Weirauch, Matthew T., Muglia, Louis J., Wang, Li, Liu, Yaping
Published in Genome Biology (16.03.2023)
Published in Genome Biology (16.03.2023)
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Journal Article
Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets
Hass, Matthew R., Brissette, Daniel, Parameswaran, Sreeja, Pujato, Mario, Donmez, Omer, Kottyan, Leah C., Weirauch, Matthew T., Kopan, Raphael
Published in PLoS genetics (10.06.2021)
Published in PLoS genetics (10.06.2021)
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Journal Article
Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition
Maezawa, So, Sakashita, Akihiko, Yukawa, Masashi, Chen, Xiaoting, Takahashi, Kazuki, Alavattam, Kris G., Nakata, Ippo, Weirauch, Matthew T., Barski, Artem, Namekawa, Satoshi H.
Published in Nature structural & molecular biology (01.10.2020)
Published in Nature structural & molecular biology (01.10.2020)
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Journal Article
Mapping and Dynamics of Regulatory DNA and Transcription Factor Networks in A. thaliana
Sullivan, Alessandra M., Arsovski, Andrej A., Lempe, Janne, Bubb, Kerry L., Weirauch, Matthew T., Sabo, Peter J., Sandstrom, Richard, Thurman, Robert E., Neph, Shane, Reynolds, Alex P., Stergachis, Andrew B., Vernot, Benjamin, Johnson, Audra K., Haugen, Eric, Sullivan, Shawn T., Thompson, Agnieszka, Neri, Fidencio V., Weaver, Molly, Diegel, Morgan, Mnaimneh, Sanie, Yang, Ally, Hughes, Timothy R., Nemhauser, Jennifer L., Queitsch, Christine, Stamatoyannopoulos, John A.
Published in Cell reports (Cambridge) (25.09.2014)
Published in Cell reports (Cambridge) (25.09.2014)
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Journal Article
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression
Hou, Guojun, Harley, Isaac T. W., Lu, Xiaoming, Zhou, Tian, Xu, Ning, Yao, Chao, Qin, Yuting, Ouyang, Ye, Ma, Jianyang, Zhu, Xinyi, Yu, Xiang, Xu, Hong, Dai, Dai, Ding, Huihua, Yin, Zhihua, Ye, Zhizhong, Deng, Jun, Zhou, Mi, Tang, Yuanjia, Namjou, Bahram, Guo, Ya, Weirauch, Matthew T., Kottyan, Leah C., Harley, John B., Shen, Nan
Published in Nature communications (08.01.2021)
Published in Nature communications (08.01.2021)
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Journal Article
Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation
Vander Lugt, Bryan, Riddell, Jeremy, Khan, Aly A., Hackney, Jason A., Lesch, Justin, DeVoss, Jason, Weirauch, Matthew T., Singh, Harinder, Mellman, Ira
Published in The Journal of cell biology (06.03.2017)
Published in The Journal of cell biology (06.03.2017)
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Journal Article
Multiple layers of transcriptional regulation by PLZF in NKT-cell development
Mao, Ai-Ping, Constantinides, Michael G., Mathew, Rebecca, Zuo, Zhixiang, Chen, Xiaoting, Weirauch, Matthew T., Bendelac, Albert
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2016)
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Journal Article
Lineage tracing of nuclei in skeletal myofibers uncovers distinct transcripts and interplay between myonuclear populations
Sun, Chengyi, Swoboda, Casey O., Morales, Fabian Montecino, Calvo, Cristofer, Petrany, Michael J., Parameswaran, Sreeja, VonHandorf, Andrew, Weirauch, Matthew T., Lepper, Christoph, Millay, Douglas P.
Published in Nature communications (30.10.2024)
Published in Nature communications (30.10.2024)
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Journal Article
maxATAC: Genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks
Cazares, Tareian A., Rizvi, Faiz W., Iyer, Balaji, Chen, Xiaoting, Kotliar, Michael, Bejjani, Anthony T., Wayman, Joseph A., Donmez, Omer, Wronowski, Benjamin, Parameswaran, Sreeja, Kottyan, Leah C., Barski, Artem, Weirauch, Matthew T., Prasath, V. B. Surya, Miraldi, Emily R.
Published in PLoS computational biology (01.01.2023)
Published in PLoS computational biology (01.01.2023)
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Journal Article
Global discovery of lupus genetic risk variant allelic enhancer activity
Lu, Xiaoming, Chen, Xiaoting, Forney, Carmy, Donmez, Omer, Miller, Daniel, Parameswaran, Sreeja, Hong, Ted, Huang, Yongbo, Pujato, Mario, Cazares, Tareian, Miraldi, Emily R., Ray, John P., de Boer, Carl G., Harley, John B., Weirauch, Matthew T., Kottyan, Leah C.
Published in Nature communications (12.03.2021)
Published in Nature communications (12.03.2021)
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Journal Article
Control of species-dependent cortico-motoneuronal connections underlying manual dexterity
Gu, Zirong, Kalamboglas, John, Yoshioka, Shin, Han, Wenqi, Li, Zhuo, Kawasawa, Yuka Imamura, Pochareddy, Sirisha, Li, Zhen, Liu, Fuchen, Xu, Xuming, Wijeratne, Sagara, Ueno, Masaki, Blatz, Emily, Salomone, Joseph, Kumanogoh, Atsushi, Rasin, Mladen-Roko, Gebelein, Brian, Weirauch, Matthew T., Sestan, Nenad, Martin, John H., Yoshida, Yutaka
Published in Science (American Association for the Advancement of Science) (28.07.2017)
Published in Science (American Association for the Advancement of Science) (28.07.2017)
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Journal Article
MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis
Pan, Wen, Zhu, Shu, Dai, Dai, Liu, Zheng, Li, Dan, Li, Bin, Gagliani, Nicola, Zheng, Yunjiang, Tang, Yuanjia, Weirauch, Matthew T., Chen, Xiaoting, Zhu, Wei, Wang, Yue, Chen, Bo, Qian, Youcun, Chen, Yingxuan, Fang, Jingyuan, Herbst, Ronald, Richman, Laura, Jallal, Bahija, Harley, John B., Flavell, Richard A., Yao, Yihong, Shen, Nan
Published in Nature communications (12.05.2015)
Published in Nature communications (12.05.2015)
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Journal Article
Type I interferon sensing unlocks dormant adipocyte inflammatory potential
Chan, Calvin C., Damen, Michelle S. M. A., Moreno-Fernandez, Maria E., Stankiewicz, Traci E., Cappelletti, Monica, Alarcon, Pablo C., Oates, Jarren R., Doll, Jessica R., Mukherjee, Rajib, Chen, Xiaoting, Karns, Rebekah, Weirauch, Matthew T., Helmrath, Michael A., Inge, Thomas H., Divanovic, Senad
Published in Nature communications (02.06.2020)
Published in Nature communications (02.06.2020)
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Journal Article