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DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules
Gerry, Christopher J, Wawer, Mathias J, Clemons, Paul A, Schreiber, Stuart L
Published in Journal of the American Chemical Society (03.07.2019)
Published in Journal of the American Chemical Society (03.07.2019)
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Journal Article
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset
Seashore-Ludlow, Brinton, Rees, Matthew G., Cheah, Jaime H., Cokol, Murat, Price, Edmund V., Coletti, Matthew E., Jones, Victor, Bodycombe, Nicole E., Soule, Christian K., Gould, Joshua, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Wawer, Mathias J., Kuru, Nurdan, Kotz, Joanne D., Hon, C. Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Bittker, Joshua A., Palmer, Michelle, Bradner, James E., Shamji, Alykhan F., Clemons, Paul A., Schreiber, Stuart L.
Published in Cancer discovery (01.11.2015)
Published in Cancer discovery (01.11.2015)
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Journal Article
Activity Landscape Representations for Structure−Activity Relationship Analysis
Wassermann, Anne Mai, Wawer, Mathias, Bajorath, Jürgen
Published in Journal of medicinal chemistry (09.12.2010)
Published in Journal of medicinal chemistry (09.12.2010)
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Journal Article
Reference compounds for characterizing cellular injury in high-content cellular morphology assays
Dahlin, Jayme L., Hua, Bruce K., Zucconi, Beth E., Nelson, Shawn D., Singh, Shantanu, Carpenter, Anne E., Shrimp, Jonathan H., Lima-Fernandes, Evelyne, Wawer, Mathias J., Chung, Lawrence P. W., Agrawal, Ayushi, O’Reilly, Mary, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Li, Fengling, Lak, Parnian, Cuellar, Matthew, Cole, Philip A., Meier, Jordan L., Thomas, Tim, Baell, Jonathan B., Brown, Peter J., Walters, Michael A., Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K.
Published in Nature communications (13.03.2023)
Published in Nature communications (13.03.2023)
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Journal Article
Mapping the landscape of genetic dependencies in chordoma
Sharifnia, Tanaz, Wawer, Mathias J., Goodale, Amy, Lee, Yenarae, Kazachkova, Mariya, Dempster, Joshua M., Muller, Sandrine, Levy, Joan, Freed, Daniel M., Sommer, Josh, Kalfon, Jérémie, Vazquez, Francisca, Hahn, William C., Root, David E., Clemons, Paul A., Schreiber, Stuart L.
Published in Nature communications (06.04.2023)
Published in Nature communications (06.04.2023)
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Journal Article
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay
Bray, Mark-Anthony, Gustafsdottir, Sigrun M, Rohban, Mohammad H, Singh, Shantanu, Ljosa, Vebjorn, Sokolnicki, Katherine L, Bittker, Joshua A, Bodycombe, Nicole E, Dančík, Vlado, Hasaka, Thomas P, Hon, Cindy S, Kemp, Melissa M, Li, Kejie, Walpita, Deepika, Wawer, Mathias J, Golub, Todd R, Schreiber, Stuart L, Clemons, Paul A, Shamji, Alykhan F, Carpenter, Anne E
Published in Gigascience (01.12.2017)
Published in Gigascience (01.12.2017)
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Journal Article
Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds
Melillo, Bruno, Zoller, Jochen, Hua, Bruce K, Verho, Oscar, Borghs, Jannik C, Nelson, Shawn D, Maetani, Micah, Wawer, Mathias J, Clemons, Paul A, Schreiber, Stuart L
Published in Journal of the American Chemical Society (19.09.2018)
Published in Journal of the American Chemical Society (19.09.2018)
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Journal Article
Chromatin-state barriers enforce an irreversible mammalian cell fate decision
Blanco, M. Andrés, Sykes, David B., Gu, Lei, Wu, Mengjun, Petroni, Ricardo, Karnik, Rahul, Wawer, Mathias, Rico, Joshua, Li, Haitao, Jacobus, William D., Jambhekar, Ashwini, Cheloufi, Sihem, Meissner, Alexander, Hochedlinger, Konrad, Scadden, David T., Shi, Yang
Published in Cell reports (Cambridge) (09.11.2021)
Published in Cell reports (Cambridge) (09.11.2021)
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Journal Article
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
Viswanathan, Srinivas R., Nogueira, Marina F., Buss, Colin G., Krill-Burger, John M., Wawer, Mathias J., Malolepsza, Edyta, Berger, Ashton C., Choi, Peter S., Shih, Juliann, Taylor, Alison M., Tanenbaum, Benjamin, Pedamallu, Chandra Sekhar, Cherniack, Andrew D., Tamayo, Pablo, Strathdee, Craig A., Lage, Kasper, Carr, Steven A., Schenone, Monica, Bhatia, Sangeeta N., Vazquez, Francisca, Tsherniak, Aviad, Hahn, William C., Meyerson, Matthew
Published in Nature genetics (01.07.2018)
Published in Nature genetics (01.07.2018)
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Journal Article
Real-Time Biological Annotation of Synthetic Compounds
Gerry, Christopher J, Hua, Bruce K, Wawer, Mathias J, Knowles, Jonathan P, Nelson Jr, Shawn D, Verho, Oscar, Dandapani, Sivaraman, Wagner, Bridget K, Clemons, Paul A, Booker-Milburn, Kevin I, Boskovic, Zarko V, Schreiber, Stuart L
Published in Journal of the American Chemical Society (20.07.2016)
Published in Journal of the American Chemical Society (20.07.2016)
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Journal Article
Data structures and computational tools for the extraction of SAR information from large compound sets
Wawer, Mathias, Lounkine, Eugen, Wassermann, Anne M., Bajorath, Jürgen
Published in Drug discovery today (01.08.2010)
Published in Drug discovery today (01.08.2010)
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Journal Article
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
Sykes, David B., Kfoury, Youmna S., Mercier, François E., Wawer, Mathias J., Law, Jason M., Haynes, Mark K., Lewis, Timothy A., Schajnovitz, Amir, Jain, Esha, Lee, Dongjun, Meyer, Hanna, Pierce, Kerry A., Tolliday, Nicola J., Waller, Anna, Ferrara, Steven J., Eheim, Ashley L., Stoeckigt, Detlef, Maxcy, Katrina L., Cobert, Julien M., Bachand, Jacqueline, Szekely, Brian A., Mukherjee, Siddhartha, Sklar, Larry A., Kotz, Joanne D., Clish, Clary B., Sadreyev, Ruslan I., Clemons, Paul A., Janzer, Andreas, Schreiber, Stuart L., Scadden, David T.
Published in Cell (22.09.2016)
Published in Cell (22.09.2016)
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Journal Article
SARANEA: A Freely Available Program To Mine Structure−Activity and Structure−Selectivity Relationship Information in Compound Data Sets
Lounkine, Eugen, Wawer, Mathias, Wassermann, Anne Mai, Bajorath, Jürgen
Published in Journal of chemical information and modeling (25.01.2010)
Published in Journal of chemical information and modeling (25.01.2010)
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Journal Article
Application of MCAT questions as a testing tool and evaluation metric for knowledge graph–based reasoning systems
Fecho, Karamarie, Balhoff, James, Bizon, Chris, Byrd, William E., Hang, Sui, Koslicki, David, Rensi, Stefano E., Schmitt, Patrick L., Wawer, Mathias J., Williams, Mark, Ahalt, Stanley C.
Published in Clinical and translational science (01.09.2021)
Published in Clinical and translational science (01.09.2021)
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Journal Article
Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
Sheppard, Hadley E., Dall’Agnese, Alessandra, Park, Woojun D., Shamim, M. Hamza, Dubrulle, Julien, Johnson, Hannah L., Stossi, Fabio, Cogswell, Patricia, Sommer, Josh, Levy, Joan, Sharifnia, Tanaz, Wawer, Mathias J., Nabet, Behnam, Gray, Nathanael S., Clemons, Paul A., Schreiber, Stuart L., Workman, Paul, Young, Richard A., Lin, Charles Y.
Published in Cell reports. Medicine (19.01.2021)
Published in Cell reports. Medicine (19.01.2021)
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Journal Article
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling
Wawer, Mathias J., Li, Kejie, Gustafsdottir, Sigrun M., Ljos, Vebjorn, Bodycombe, Nicole E., Marton, Melissa A., Sokolnicki, Katherine L., Bray, Mark-Anthony, Kemp, Melissa M., Winchester, Ellen, Taylor, Bradley, Grant, George B., Hon, C. Suk-Yee, Duvall, Jeremy R., Wilson, J. Anthony, Bittker, Joshua A., Dančík, Vlado, Narayan, Rajiv, Subramanian, Aravind, Winckler, Wendy, Golub, Todd R., Carpenter, Anne E., Shamji, Alykhan F., Schreiber, Stuart L., Clemons, Paul A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
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Journal Article
Automated Structure–Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles
Wawer, Mathias J., Jaramillo, David E., Dančík, Vlado, Fass, Daniel M., Haggarty, Stephen J., Shamji, Alykhan F., Wagner, Bridget K., Schreiber, Stuart L., Clemons, Paul A.
Published in SLAS discovery (01.06.2014)
Published in SLAS discovery (01.06.2014)
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Journal Article