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6‑Alkoxy-5-aryl-3-pyridinecarboxamides, a New Series of Bioavailable Cannabinoid Receptor Type 1 (CB1) Antagonists Including Peripherally Selective Compounds
Röver, Stephan, Andjelkovic, Mirjana, Bénardeau, Agnès, Chaput, Evelyne, Guba, Wolfgang, Hebeisen, Paul, Mohr, Susanne, Nettekoven, Matthias, Obst, Ulrike, Richter, Wolfgang F, Ullmer, Christoph, Waldmeier, Pius, Wright, Matthew B
Published in Journal of medicinal chemistry (27.12.2013)
Published in Journal of medicinal chemistry (27.12.2013)
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Journal Article
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction
Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard, Waldmeier, Pius
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
Published in Bioorganic & medicinal chemistry letters (01.10.2009)
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Journal Article
Efficient Enantioselective Synthesis of the NMDA 2B Receptor Antagonist Ro 67-8867
Scalone, Michelangelo, Waldmeier, Pius
Published in Organic process research & development (01.05.2003)
Published in Organic process research & development (01.05.2003)
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Journal Article
Efficient Synthesis of Novel NK1 Receptor Antagonists: Selective 1,4-Addition of Grignard Reagents to 6-Chloronicotinic Acid Derivatives
Hoffmann-Emery, Fabienne, Hilpert, Hans, Scalone, Michelangelo, Waldmeier, Pius
Published in Journal of organic chemistry (03.03.2006)
Published in Journal of organic chemistry (03.03.2006)
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Journal Article
PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS
IDING HANS, WALDMEIER PIUS, DOTT PASCAL, HANLON STEVEN PAUL, HILDBRAND STEFAN, THOMAS ANDREW
Year of Publication 28.01.2020
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Year of Publication 28.01.2020
Patent
Benzodioxoles: Novel Cannabinoid-1 Receptor Inverse Agonists for the Treatment of Obesity
Alig, Leo, Alsenz, Jochem, Andjelkovic, Mirjana, Bendels, Stefanie, Bénardeau, Agnès, Bleicher, Konrad, Bourson, Anne, David-Pierson, Pascale, Guba, Wolfgang, Hildbrand, Stefan, Kube, Dagmar, Lübbers, Thomas, Mayweg, Alexander V, Narquizian, Robert, Neidhart, Werner, Nettekoven, Matthias, Plancher, Jean-Marc, Rocha, Cynthia, Rogers-Evans, Mark, Röver, Stephan, Schneider, Gisbert, Taylor, Sven, Waldmeier, Pius
Published in Journal of medicinal chemistry (10.04.2008)
Published in Journal of medicinal chemistry (10.04.2008)
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Journal Article
Efficient Synthesis of a 5-HT2C Receptor Agonist Precursor
Peters, René, Waldmeier, Pius, Joncour, Agnès
Published in Organic process research & development (01.07.2005)
Published in Organic process research & development (01.07.2005)
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Journal Article
Efficient Synthesis of Novel NK 1 Receptor Antagonists: Selective 1,4-Addition of Grignard Reagents to 6-Chloronicotinic Acid Derivatives
Hoffmann-Emery, Fabienne, Hilpert, Hans, Scalone, Michelangelo, Waldmeier, Pius
Published in Journal of organic chemistry (01.03.2006)
Published in Journal of organic chemistry (01.03.2006)
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Journal Article
PROCESS FOR THE PREPARATION OF ISOXAZOLYL-METHOXY-NICOTINIC ACIDS
IDING HANS, WALDMEIER PIUS, DOTT PASCAL, HANLON STEVEN PAUL, HILDBRAND STEFAN, THOMAS ANDREW
Year of Publication 04.07.2014
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Year of Publication 04.07.2014
Patent
Efficient Synthesis of a 5-HT 2C Receptor Agonist Precursor
Peters, René, Waldmeier, Pius, Joncour, Agnès
Published in Organic process research & development (01.07.2005)
Published in Organic process research & development (01.07.2005)
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Journal Article
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction
Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W, Trube, Gerhard, Waldmeier, Pius
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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Journal Article
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABA sub(A) alpha 5 inverse agonists for the treatment of cognitive dysfunction
Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frederic, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W, Trube, Gerhard, Waldmeier, Pius
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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Journal Article
Radiosynthesis of [5-[11C]methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindol-2-yl]-methanone ([11C]RO5013853), a novel PET tracer for the glycine transporter type I (GlyT1)
Pinard, Emmanuel, Burner, Serge, Cueni, Philipp, Hartung, Thomas, Norcross, Roger D., Schmid, Philipp, Waldmeier, Pius, Zielinski, Guy, Ravert, Hayden T., Holt, Daniel P., Dannals, Robert F.
Published in Journal of labelled compounds & radiopharmaceuticals (01.09.2011)
Published in Journal of labelled compounds & radiopharmaceuticals (01.09.2011)
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Journal Article
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABA A α5 inverse agonists for the treatment of cognitive dysfunction
Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard, Waldmeier, Pius
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article
The discovery and unique pharmacological profile of RO4938581 and R04882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction
KNUST, Henner, ACHERMANN, Guido, THOMAS, Andrew W, TRUBE, Gerhard, WALDMEIER, Pius, BALLARD, Theresa, BUETTELMANN, Bernd, GASSER, Rodolfo, FISCHER, Holger, HERNANDEZ, Maria-Clemencia, KNOFLACH, Frédéric, KOBLET, Andreas, STADLER, Heinz
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
Journal Article
1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS
MUELLER WERNER, WALDMEIER PIUS, OBST SANDER ULRIKE, HUNZIKER DANIEL, LERNER CHRISTIAN, PFLIEGER PHILIPPE
Year of Publication 08.11.2011
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Year of Publication 08.11.2011
Patent
2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS
MUELLER WERNER, WALDMEIER PIUS, OBST SANDER ULRIKE, HUNZIKER DANIEL, LERNER CHRISTIAN, PFLIEGER PHILIPPE
Year of Publication 01.11.2011
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Year of Publication 01.11.2011
Patent
2-TRIFLUOROMETHYLNICOTINAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS
WRIGHT MATTHEW, WALDMEIER PIUS, PANOUSIS CONSTANTINOS G, ROEVER STEPHAN, HEBEISEN PAUL
Year of Publication 02.11.2010
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Year of Publication 02.11.2010
Patent