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Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map
Bayraktar, Omer Ali, Bartels, Theresa, Holmqvist, Staffan, Kleshchevnikov, Vitalii, Martirosyan, Araks, Polioudakis, Damon, Ben Haim, Lucile, Young, Adam M. H., Batiuk, Mykhailo Y., Prakash, Kirti, Brown, Alexander, Roberts, Kenny, Paredes, Mercedes F., Kawaguchi, Riki, Stockley, John H., Sabeur, Khalida, Chang, Sandra M., Huang, Eric, Hutchinson, Peter, Ullian, Erik M., Hemberg, Martin, Coppola, Giovanni, Holt, Matthew G., Geschwind, Daniel H., Rowitch, David H.
Published in Nature neuroscience (01.04.2020)
Published in Nature neuroscience (01.04.2020)
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Journal Article
Zika virus cell tropism in the developing human brain and inhibition by azithromycin
Retallack, Hanna, Di Lullo, Elizabeth, Arias, Carolina, Knopp, Kristeene A., Laurie, Matthew T., Sandoval-Espinosa, Carmen, Leon, Walter R. Mancia, Krencik, Robert, Ullian, Erik M., Spatazza, Julien, Pollen, Alex A., Mandel-Brehm, Caleigh, Nowakowski, Tomasz J., Kriegstein, Arnold R., DeRisi, Joseph L.
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2016)
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Journal Article
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
Leng, Kun, Rose, Indigo V. L., Kim, Hyosung, Xia, Wenlong, Romero-Fernandez, Wilber, Rooney, Brendan, Koontz, Mark, Li, Emmy, Ao, Yan, Wang, Shinong, Krawczyk, Mitchell, TCW, Julia, Goate, Alison, Zhang, Ye, Ullian, Erik M., Sofroniew, Michael V., Fancy, Stephen P. J., Schrag, Matthew S., Lippmann, Ethan S., Kampmann, Martin
Published in Nature neuroscience (01.11.2022)
Published in Nature neuroscience (01.11.2022)
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Journal Article
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Minhas, Paras S., Jones, Jeffrey R., Latif-Hernandez, Amira, Sugiura, Yuki, Durairaj, Aarooran S., Wang, Qian, Mhatre, Siddhita D., Uenaka, Takeshi, Crapser, Joshua, Conley, Travis, Ennerfelt, Hannah, Jung, Yoo Jin, Liu, Ling, Prasad, Praveena, Jenkins, Brenita C., Ay, Yeonglong Albert, Matrongolo, Matthew, Goodman, Ryan, Newmeyer, Traci, Heard, Kelly, Kang, Austin, Wilson, Edward N., Yang, Tao, Ullian, Erik M., Serrano, Geidy E., Beach, Thomas G., Wernig, Marius, Rabinowitz, Joshua D., Suematsu, Makoto, Longo, Frank M., McReynolds, Melanie R., Gage, Fred H., Andreasson, Katrin I.
Published in Science (23.08.2024)
Published in Science (23.08.2024)
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Journal Article
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency
Zhang, Jiasheng, Velmeshev, Dmitry, Hashimoto, Kei, Huang, Yu-Hsin, Hofmann, Jeffrey W., Shi, Xiaoyu, Chen, Jiapei, Leidal, Andrew M., Dishart, Julian G., Cahill, Michelle K., Kelley, Kevin W., Liddelow, Shane A., Seeley, William W., Miller, Bruce L., Walther, Tobias C., Farese, Robert V., Taylor, J. Paul, Ullian, Erik M., Huang, Bo, Debnath, Jayanta, Wittmann, Torsten, Kriegstein, Arnold R., Huang, Eric J.
Published in Nature (London) (17.12.2020)
Published in Nature (London) (17.12.2020)
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Journal Article
Machine learning dissection of human accelerated regions in primate neurodevelopment
Whalen, Sean, Inoue, Fumitaka, Ryu, Hane, Fair, Tyler, Markenscoff-Papadimitriou, Eirene, Keough, Kathleen, Kircher, Martin, Martin, Beth, Alvarado, Beatriz, Elor, Orry, Laboy Cintron, Dianne, Williams, Alex, Hassan Samee, Md. Abul, Thomas, Sean, Krencik, Robert, Ullian, Erik M., Kriegstein, Arnold, Rubenstein, John L., Shendure, Jay, Pollen, Alex A., Ahituv, Nadav, Pollard, Katherine S.
Published in Neuron (Cambridge, Mass.) (15.03.2023)
Published in Neuron (Cambridge, Mass.) (15.03.2023)
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Journal Article
CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma
Liu, S. John, Malatesta, Martina, Lien, Brian V., Saha, Parna, Thombare, Shivani S., Hong, Sung Jun, Pedraza, Leslie, Koontz, Mark, Seo, Kyounghee, Horlbeck, Max A., He, Daniel, Birk, Harjus S., Jain, Miten, Olsen, Hugh E., Akeson, Mark, Weissman, Jonathan S., Monje, Michelle, Gupta, Nalin, Raleigh, David R., Ullian, Erik M., Lim, Daniel A.
Published in Genome Biology (31.03.2020)
Published in Genome Biology (31.03.2020)
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Journal Article
Human stem cell–derived astrocytes replicate human prions in a PRNP genotype–dependent manner
Krejciova, Zuzana, Alibhai, James, Zhao, Chen, Krencik, Robert, Rzechorzek, Nina M., Ullian, Erik M., Manson, Jean, Ironside, James W., Head, Mark W., Chandran, Siddharthan
Published in The Journal of experimental medicine (04.12.2017)
Published in The Journal of experimental medicine (04.12.2017)
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Journal Article
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder
Deshpande, Aditi, Yadav, Smita, Dao, Dang Q., Wu, Zhi-Yong, Hokanson, Kenton C., Cahill, Michelle K., Wiita, Arun P., Jan, Yuh-Nung, Ullian, Erik M., Weiss, Lauren A.
Published in Cell reports (Cambridge) (05.12.2017)
Published in Cell reports (Cambridge) (05.12.2017)
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Journal Article
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
Magill, Stephen T., Vasudevan, Harish N., Seo, Kyounghee, Villanueva-Meyer, Javier E., Choudhury, Abrar, John Liu, S., Pekmezci, Melike, Findakly, Sarah, Hilz, Stephanie, Lastella, Sydney, Demaree, Benjamin, Braunstein, Steve E., Bush, Nancy Ann Oberheim, Aghi, Manish K., Theodosopoulos, Philip V., Sneed, Penny K., Abate, Adam R., Berger, Mitchel S., McDermott, Michael W., Lim, Daniel A., Ullian, Erik M., Costello, Joseph F., Raleigh, David R.
Published in Nature communications (23.09.2020)
Published in Nature communications (23.09.2020)
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Journal Article
Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus
Davis, Tigwa H, Cuellar, Trinna L, Koch, Selina M, Barker, Allison J, Harfe, Brian D, McManus, Michael T, Ullian, Erik M
Published in The Journal of neuroscience (23.04.2008)
Published in The Journal of neuroscience (23.04.2008)
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Journal Article
Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations
Marsan, Elise, Velmeshev, Dmitry, Ramsey, Arren, Patel, Ravi K., Zhang, Jiasheng, Koontz, Mark, Andrews, Madeline G., de Majo, Martina, Mora, Cristina, Blumenfeld, Jessica, Li, Alissa N., Spina, Salvatore, Grinberg, Lea T., Seeley, William W., Miller, Bruce L., Ullian, Erik M., Krummel, Matthew F., Kriegstein, Arnold R., Huang, Eric J.
Published in The Journal of clinical investigation (15.03.2023)
Published in The Journal of clinical investigation (15.03.2023)
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Journal Article
Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS
Bekier, Michael E., Pinarbasi, Emile, Krishnan, Gopinath, Mesojedec, Jack J., Hurley, Madelaine, Harikumar Sheela, Harisankar, Collins, Catherine A., Ghaffari, Layla, de Majo, Martina, Ullian, Erik M., Koontz, Mark, Coleman, Sarah, Li, Xingli, Tank, Elizabeth M.H., Waksmacki, Jacob, Gao, Fen-Biao, Barmada, Sami J.
Published in The Journal of clinical investigation (02.09.2025)
Published in The Journal of clinical investigation (02.09.2025)
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Journal Article
Architecture and Activity-Mediated Refinement of Axonal Projections from a Mosaic of Genetically Identified Retinal Ganglion Cells
Huberman, Andrew D., Manu, Mihai, Koch, Selina M., Susman, Michael W., Lutz, Amanda Brosius, Ullian, Erik M., Baccus, Stephen A., Barres, Ben A.
Published in Neuron (Cambridge, Mass.) (14.08.2008)
Published in Neuron (Cambridge, Mass.) (14.08.2008)
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Journal Article
Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
Krencik, Robert, Seo, Kyounghee, van Asperen, Jessy V., Basu, Nupur, Cvetkovic, Caroline, Barlas, Saba, Chen, Robert, Ludwig, Connor, Wang, Chao, Ward, Michael E., Gan, Li, Horner, Philip J., Rowitch, David H., Ullian, Erik M.
Published in Stem cell reports (12.12.2017)
Published in Stem cell reports (12.12.2017)
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Journal Article
Pathway-Specific Genetic Attenuation of Glutamate Release Alters Select Features of Competition-Based Visual Circuit Refinement
Koch, Selina M., Dela Cruz, Cassandra G., Hnasko, Thomas S., Edwards, Robert H., Huberman, Andrew D., Ullian, Erik M.
Published in Neuron (Cambridge, Mass.) (28.07.2011)
Published in Neuron (Cambridge, Mass.) (28.07.2011)
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Journal Article
Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent
Shen, Yun-An A., Chen, Yan, Dao, Dang Q., Mayoral, Sonia R., Wu, Laiman, Meijer, Dies, Ullian, Erik M., Chan, Jonah R., Lu, Q. Richard
Published in Nature communications (26.09.2014)
Published in Nature communications (26.09.2014)
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Journal Article