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Safety, Pharmacokinetics and Immunogenicity of Single and Multiple Ascending Doses of the Anti‐Tau Therapeutic Antibody E2814: A Phase 1, First‐In‐Human (FIH) Study in Healthy Subjects
Rawal, Sumit, Yagi, Takuya, Boyd, Peter, Aluri, Jagadeesh, Wildsmith, Kristin R, Reyderman, Larisa
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Contribution of enhanced engagement of antigen presentation machinery to the clinical immunogenicity of a human interleukin (IL)‐21 receptor‐blocking therapeutic antibody
Xue, L., Hickling, T., Song, R., Nowak, J., Rup, B.
Published in Clinical and experimental immunology (01.01.2016)
Published in Clinical and experimental immunology (01.01.2016)
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Journal Article
Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities
Farrokhi, Vahid, Chabot, Jeffrey R., Neubert, Hendrik, Yang, Zhiyong
Published in Scientific reports (17.05.2018)
Published in Scientific reports (17.05.2018)
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Journal Article
Pharmacokinetics, immunogenicity and bioactivity of the therapeutic antibody catumaxomab intraperitoneally administered to cancer patients
Ruf, Peter, Kluge, Michael, Jäger, Michael, Burges, Alexander, Volovat, Constantin, Heiss, Markus Maria, Hess, Jürgen, Wimberger, Pauline, Brandt, Birgit, Lindhofer, Horst
Published in British journal of clinical pharmacology (01.06.2010)
Published in British journal of clinical pharmacology (01.06.2010)
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Journal Article
First-in-Human Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Rapidly Developed SARS-CoV-2 Therapeutic Antibody, AOD01, in Healthy Adults
Prativadibhayankaram, Venkateshan S., Lee, Lawrence Soon-U, Lye, David, Xiaoying, Xu, Nellore, Ranjani, Pendharkar, Vishal, Hentze, Hannes, Guan, Siyu, Ayers, Benjamin J., Seah, Shirley G. K., Chye, De Hoe, Talib, Najwa S. N., Kaliaperumal, Nivashini, Ong, Wei Yee, Wong, Zi Xin, Au, Veonice B., Alok, Anshula, Connolly, John E., Boyd-Kirkup, Jerome D., Ingram, Piers J., Hanson, Brendon J., Ethirajulu, Kantharaj, O’Connell, Damian, Chan, Conrad E. Z.
Published in Infectious diseases and therapy (01.10.2022)
Published in Infectious diseases and therapy (01.10.2022)
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Journal Article
Safety, pharmacokinetics, and preliminary efficacy of a specific anti-IL-1alpha therapeutic antibody (MABp1) in patients with type 2 diabetes mellitus
Timper, Katharina, Seelig, Eleonora, Tsakiris, Dimitrios A., Donath, Marc Y.
Published in Journal of diabetes and its complications (01.09.2015)
Published in Journal of diabetes and its complications (01.09.2015)
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Journal Article
218 A preclinical study of IMC-002, a fully human therapeutic antibody safely targeting CD47 in cancer
Yoo, Hyeonseok, Kim, Jeong Kook, Ji Yea Choi, Song, Sun Kwang, Park, Jihyun, Jeon, Ara, Ji Hye Lee, Chang, Sook Kyung, Song, Yun
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
A phase I/IIA safety study of NPC-1C: A novel, therapeutic antibody to treat pancreas and colorectal cancers
Morse, Michael, Diaz, Luis A., Azad, Nilofer Saba, Laheru, Dan, Haley, Sherri, Sleer, Leanne Sophia, Arlen, Philip M.
Published in Journal of clinical oncology (01.02.2012)
Published in Journal of clinical oncology (01.02.2012)
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Journal Article
THERAPEUTIC ANTIBODY TARGETING WISP1 PROTEIN
YAWORSKY, Paul, DOWER, Gabriela, FETHEROLF, Morgan, ESPELIN, Christopher, DEVINE, Erin, TAVARES, Daniel
Year of Publication 31.07.2025
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Year of Publication 31.07.2025
Patent
Improvement of pharmacokinetic properties of therapeutic antibodies by antibody engineering
Haraya, Kenta, Tachibana, Tatsuhiko, Igawa, Tomoyuki
Published in Drug metabolism and pharmacokinetics (01.02.2019)
Published in Drug metabolism and pharmacokinetics (01.02.2019)
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Journal Article
Therapeutic antibody fragments, methods of making, and methods of use
Kunamneni, Adinarayana, Westlund High, Karin, Durvasula, Ravi Venkata
Year of Publication 19.11.2024
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Year of Publication 19.11.2024
Patent
Treatment Involving Therapeutic Antibody and Interleukin-2 (IL2)
Vormehr, Mathias, Beck, Jan David, Diken, Mustafa, Kreiter, Sebastian, Sahin, Ugur
Year of Publication 01.12.2022
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Year of Publication 01.12.2022
Patent
Specificity of the T Cell Response to Protein Biopharmaceuticals
Meunier, Sylvain, de Bourayne, Marie, Hamze, Moustafa, Azam, Aurélien, Correia, Evelyne, Menier, Catherine, Maillère, Bernard
Published in Frontiers in immunology (22.07.2020)
Published in Frontiers in immunology (22.07.2020)
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Journal Article
Web Resource
TREATMENT INVOLVING THERAPEUTIC ANTIBODY AND INTERLEUKIN-2 (IL2)
KREITER, Sebastian, VORMEHR, Mathias, DIKEN, Mustafa, SAHIN, Ugur, BECK, Jan David
Year of Publication 03.08.2022
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Year of Publication 03.08.2022
Patent
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors
Panousis, Con, Dhagat, Urmi, Edwards, Kirsten M., Rayzman, Veronika, Hardy, Matthew P., Braley, Hal, Gauvreau, Gail M., Hercus, Timothy R., Smith, Steven, Sehmi, Roma, McMillan, Laura, Dottore, Mara, McClure, Barbara J., Fabri, Louis J., Vairo, Gino, Lopez, Angel F, Parker, Michael W., Nash, Andrew D., Wilson, Nicholas J., Wilson, Michael J., Owczarek, Catherine M.
Published in mAbs (02.04.2016)
Published in mAbs (02.04.2016)
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Journal Article