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Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells
Kim, KiBem, Skora, Andrew D., Li, Zhaobo, Liu, Qiang, Tam, Ada J., Blosser, Richard L., Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (12.08.2014)
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Journal Article
IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis
Faust, Heather J., Zhang, Hong, Han, Jin, Wolf, Matthew T., Jeon, Ok Hee, Sadtler, Kaitlyn, Peña, Alexis N., Chung, Liam, Maestas, David R., Tam, Ada J., Pardoll, Drew M., Campisi, Judith, Housseau, Franck, Zhou, Daohong, Bingham, Clifton O., Elisseeff, Jennifer H.
Published in The Journal of clinical investigation (01.10.2020)
Published in The Journal of clinical investigation (01.10.2020)
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Journal Article
Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
Chung, Liam, Thiele Orberg, Erik, Geis, Abby L., Chan, June L., Fu, Kai, DeStefano Shields, Christina E., Dejea, Christine M., Fathi, Payam, Chen, Jie, Finard, Benjamin B., Tam, Ada J., McAllister, Florencia, Fan, Hongni, Wu, Xinqun, Ganguly, Sudipto, Lebid, Andriana, Metz, Paul, Van Meerbeke, Sara W., Huso, David L., Wick, Elizabeth C., Pardoll, Drew M., Wan, Fengyi, Wu, Shaoguang, Sears, Cynthia L., Housseau, Franck
Published in Cell host & microbe (14.02.2018)
Published in Cell host & microbe (14.02.2018)
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Journal Article
The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures
Chen, Lingling, Oke, Teniola, Siegel, Nicholas, Cojocaru, Gady, Tam, Ada J., Blosser, Richard L., Swailes, Jessica, Ligon, John A., Lebid, Andriana, Morris, Carol, Levin, Adam, Rhee, Daniel S., Johnston, Fabian M., Greer, Jonathan B., Meyer, Christian F., Ladle, Brian H., Thompson, Elizabeth D., Montgomery, Elizabeth A., Choi, Woonyoung, McConkey, David J., Anders, Robert A., Pardoll, Drew M., Llosa, Nicolas J.
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
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Journal Article
Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A
Chan, June L., Wu, Shaoguang, Geis, Abby L., Chan, Gabrielle V., Gomes, Talles A.M., Beck, Sarah E., Wu, Xinqun, Fan, Hongni, Tam, Ada J., Chung, Liam, Ding, Hua, Wang, Hao, Pardoll, Drew M., Housseau, Franck, Sears, Cynthia L.
Published in Mucosal immunology (01.01.2019)
Published in Mucosal immunology (01.01.2019)
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Journal Article
Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors
Llosa, Nicolas J., Luber, Brandon, Tam, Ada J., Smith, Kellie N., Siegel, Nicholas, Awan, Anas H., Fan, Hongni, Oke, Teniola, Zhang, JiaJia, Domingue, Jada, Engle, Elizabeth L., Roberts, Charles A., Bartlett, Bjarne R., Aulakh, Laveet K., Thompson, Elizabeth D., Taube, Janis M., Durham, Jennifer N., Sears, Cynthia L., Le, Dung T., Diaz, Luis A., Pardoll, Drew M., Wang, Hao, Anders, Robert A., Housseau, Franck
Published in Clinical cancer research (01.09.2019)
Published in Clinical cancer research (01.09.2019)
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Journal Article
Phenotypic and Functional Properties of Helios+ Regulatory T Cells
Zabransky, Daniel J., Nirschl, Christopher J., Durham, Nicholas M., Park, Ben V., Ceccato, Christina M., Bruno, Tullia C., Tam, Ada J., Getnet, Derese, Drake, Charles G.
Published in PloS one (30.03.2012)
Published in PloS one (30.03.2012)
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Journal Article
mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages
Oh, Min-Hee, Collins, Samuel L., Sun, Im-Hong, Tam, Ada J., Patel, Chirag H., Arwood, Matthew L., Chan-Li, Yee, Powell, Jonathan D., Horton, Maureen R.
Published in Cell reports (Cambridge) (05.09.2017)
Published in Cell reports (Cambridge) (05.09.2017)
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Journal Article
Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes
Ligon, John A, Choi, Woonyoung, Cojocaru, Gady, Fu, Wei, Hsiue, Emily Han-Chung, Oke, Teniola F, Siegel, Nicholas, Fong, Megan H, Ladle, Brian, Pratilas, Christine A, Morris, Carol D, Levin, Adam, Rhee, Daniel S, Meyer, Christian F, Tam, Ada J, Blosser, Richard, Thompson, Elizabeth D, Suru, Aditya, McConkey, David, Housseau, Franck, Anders, Robert, Pardoll, Drew M, Llosa, Nicolas
Published in Journal for immunotherapy of cancer (01.05.2021)
Published in Journal for immunotherapy of cancer (01.05.2021)
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Journal Article
Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes
Skora, Andrew D., Douglass, Jacqueline, Hwang, Michael S., Tam, Ada J., Blosser, Richard L., Gabelli, Sandra B., Cao, Jianhong, Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
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Journal Article
An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial
Anderson, Amy E., Wu, Iwen, Parrillo, Alexis J., Wolf, Matthew T., Maestas, David R., Graham, Ian, Tam, Ada J., Payne, Rachael M., Aston, Jeffrey, Cooney, Carisa M., Byrne, Patrick, Cooney, Damon S., Elisseeff, Jennifer H.
Published in npj Regenerative medicine (14.01.2022)
Published in npj Regenerative medicine (14.01.2022)
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Journal Article
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells
Oh, Min-Hee, Sun, Im-Hong, Zhao, Liang, Leone, Robert D., Sun, Im-Meng, Xu, Wei, Collins, Samuel L., Tam, Ada J., Blosser, Richard L., Patel, Chirag H., Englert, Judson M., Arwood, Matthew L., Wen, Jiayu, Chan-Li, Yee, Tenora, Lukáš, Majer, Pavel, Rais, Rana, Slusher, Barbara S., Horton, Maureen R., Powell, Jonathan D.
Published in The Journal of clinical investigation (01.07.2020)
Published in The Journal of clinical investigation (01.07.2020)
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Journal Article
STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients
Vasquez-Dunddel, David, Pan, Fan, Zeng, Qi, Gorbounov, Mikhail, Albesiano, Emilia, Fu, Juan, Blosser, Richard L., Tam, Ada J., Bruno, Tullia, Zhang, Hao, Pardoll, Drew, Kim, Young
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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Journal Article
Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells
Sadtler, Kaitlyn, Estrellas, Kenneth, Allen, Brian W., Wolf, Matthew T., Fan, Hongni, Tam, Ada J., Patel, Chirag H., Luber, Brandon S., Wang, Hao, Wagner, Kathryn R., Powell, Jonathan D., Housseau, Franck, Pardoll, Drew M., Elisseeff, Jennifer H.
Published in Science (American Association for the Advancement of Science) (15.04.2016)
Published in Science (American Association for the Advancement of Science) (15.04.2016)
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Journal Article
mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells
Sun, Im-Hong, Oh, Min-Hee, Zhao, Liang, Patel, Chirag H, Arwood, Matthew L, Xu, Wei, Tam, Ada J, Blosser, Richard L, Wen, Jiayu, Powell, Jonathan D
Published in The Journal of immunology (1950) (15.07.2018)
Published in The Journal of immunology (1950) (15.07.2018)
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Journal Article
Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation
Pollizzi, Kristen N, Sun, Im-Hong, Patel, Chirag H, Lo, Ying-Chun, Oh, Min-Hee, Waickman, Adam T, Tam, Ada J, Blosser, Richard L, Wen, Jiayu, Delgoffe, Greg M, Powell, Jonathan D
Published in Nature immunology (01.06.2016)
Published in Nature immunology (01.06.2016)
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Journal Article
Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non–Small Cell Lung Cancer
Zhang, Jiajia, Ji, Zhicheng, Caushi, Justina X., El Asmar, Margueritta, Anagnostou, Valsamo, Cottrell, Tricia R., Chan, Hok Yee, Suri, Prerna, Guo, Haidan, Merghoub, Taha, Chaft, Jamie E., Reuss, Joshua E., Tam, Ada J., Blosser, Richard L., Abu-Akeel, Mohsen, Sidhom, John-William, Zhao, Ni, Ha, Jinny S., Jones, David R., Marrone, Kristen A., Naidoo, Jarushka, Gabrielson, Edward, Taube, Janis M., Velculescu, Victor E., Brahmer, Julie R., Housseau, Franck, Hellmann, Matthew D., Forde, Patrick M., Pardoll, Drew M., Ji, Hongkai, Smith, Kellie N.
Published in Clinical cancer research (15.03.2020)
Published in Clinical cancer research (15.03.2020)
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Journal Article
Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors
Bai, Ren-Yuan, Esposito, Dominic, Tam, Ada J., McCormick, Frank, Riggins, Gregory J., Wade Clapp, D., Staedtke, Verena
Published in Gene therapy (01.06.2019)
Published in Gene therapy (01.06.2019)
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Journal Article
Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy
DeStefano Shields, Christina E., White, James R., Chung, Liam, Wenzel, Alyssa, Hicks, Jessica L., Tam, Ada J., Chan, June L., Dejea, Christine M., Fan, Hongni, Michel, John, Maiuri, Ashley R., Sriramkumar, Shruthi, Podicheti, Ram, Rusch, Douglas B., Wang, Hao, De Marzo, Angelo M., Besharati, Sepideh, Anders, Robert A., Baylin, Stephen B., O'Hagan, Heather M., Housseau, Franck, Sears, Cynthia L.
Published in Cancer discovery (01.07.2021)
Published in Cancer discovery (01.07.2021)
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Journal Article
GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation
Xu, Wei, Patel, Chirag H., Alt, Jesse, Zhao, Liang, Sun, Im-Hong, Oh, Min-Hee, Sun, Im-Meng, Wen, Jiayu, Blosser, Richard L., Tam, Ada J., Powell, Jonathan D.
Published in Nature (London) (02.02.2023)
Published in Nature (London) (02.02.2023)
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Journal Article