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Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC
Swartling, Fredrik J., Savov, Vasil, Persson, Anders I., Chen, Justin, Hackett, Christopher S., Northcott, Paul A., Grimmer, Matthew R., Lau, Jasmine, Chesler, Louis, Perry, Arie, Phillips, Joanna J., Taylor, Michael D., Weiss, William A.
Published in Cancer cell (15.05.2012)
Published in Cancer cell (15.05.2012)
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Journal Article
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H., Miller, Matthew L., Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K., McHenry, Lauren K., An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence M.G., Luu, Betty, Moriarity, Branden S., Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M., Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M., Dirks, Peter, Snyder, Michael P., Largaespada, David A., Cho, Yoon Jae, Phillips, Joanna J., Swartling, Fredrik J., Morrissy, A. Sorana, Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Smith, Austin, Weiss, William A.
Published in Cell stem cell (05.09.2019)
Published in Cell stem cell (05.09.2019)
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Journal Article
Targeting MYCN in Molecularly Defined Malignant Brain Tumors
Borgenvik, Anna, Čančer, Matko, Hutter, Sonja, Swartling, Fredrik J.
Published in Frontiers in oncology (28.01.2021)
Published in Frontiers in oncology (28.01.2021)
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Journal Article
Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development—Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus
Truvé, Katarina, Dickinson, Peter, Xiong, Anqi, York, Daniel, Jayashankar, Kartika, Pielberg, Gerli, Koltookian, Michele, Murén, Eva, Fuxelius, Hans-Henrik, Weishaupt, Holger, Swartling, Fredrik J., Andersson, Göran, Hedhammar, Åke, Bongcam-Rudloff, Erik, Forsberg-Nilsson, Karin, Bannasch, Danika, Lindblad-Toh, Kerstin
Published in PLoS genetics (12.05.2016)
Published in PLoS genetics (12.05.2016)
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Journal Article
ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
Mainwaring, Oliver J., Weishaupt, Holger, Zhao, Miao, Rosén, Gabriela, Borgenvik, Anna, Breinschmid, Laura, Verbaan, Annemieke D., Richardson, Stacey, Thompson, Dean, Clifford, Steven C., Hill, Rebecca M., Annusver, Karl, Sundström, Anders, Holmberg, Karl O., Kasper, Maria, Hutter, Sonja, Swartling, Fredrik J.
Published in Nature communications (03.03.2023)
Published in Nature communications (03.03.2023)
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Journal Article
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma
Suryo Rahmanto, Aldwin, Savov, Vasil, Brunner, Andrä, Bolin, Sara, Weishaupt, Holger, Malyukova, Alena, Rosén, Gabriela, Čančer, Matko, Hutter, Sonja, Sundström, Anders, Kawauchi, Daisuke, Jones, David TW, Spruck, Charles, Taylor, Michael D, Cho, Yoon-Jae, Pfister, Stefan M, Kool, Marcel, Korshunov, Andrey, Swartling, Fredrik J, Sangfelt, Olle
Published in The EMBO journal (17.10.2016)
Published in The EMBO journal (17.10.2016)
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Journal Article
Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma
Lindell, Emma, Guo, Jing, Zhao, Miao, Rameika, Natallia, Lu, Xi, Wacker, Tabea, Zhong, Lei, Bergström, Tobias, Svanberg, Sara, Chowdhury, Azazul I., Bergsten, Peter, Chen, Xingqi, Bexell, Daniel, Swartling, Fredrik J., Sjöblom, Tobias, Zhang, Xiaonan
Published in Cell death & disease (23.07.2025)
Published in Cell death & disease (23.07.2025)
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Journal Article
Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells
Lu, Xi, Zhong, Lei, Lindell, Emma, Veanes, Margus, Guo, Jing, Zhao, Miao, Salehi, Maede, Swartling, Fredrik J., Chen, Xingqi, Sjöblom, Tobias, Zhang, Xiaonan
Published in Cell death & disease (13.10.2023)
Published in Cell death & disease (13.10.2023)
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Journal Article
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma
Simonds, Erin F, Lu, Edbert D, Badillo, Oscar, Karimi, Shokoufeh, Liu, Eric V, Tamaki, Whitney, Rancan, Chiara, Downey, Kira M, Stultz, Jacob, Sinha, Meenal, McHenry, Lauren K, Nasholm, Nicole M, Chuntova, Pavlina, Sundström, Anders, Genoud, Vassilis, Shahani, Shilpa A, Wang, Leo D, Brown, Christine E, Walker, Paul R, Swartling, Fredrik J, Fong, Lawrence, Okada, Hideho, Weiss, William A, Hellström, Mats
Published in Journal for immunotherapy of cancer (01.06.2021)
Published in Journal for immunotherapy of cancer (01.06.2021)
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Journal Article
Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Published in Nature communications (08.10.2018)
Published in Nature communications (08.10.2018)
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Journal Article
Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Trieu, Kenneth G., Tsai, Shih-Ying, Eberl, Markus, Ju, Virginia, Ford, Noah C., Doane, Owen J., Peterson, Jamie K., Veniaminova, Natalia A., Grachtchouk, Marina, Harms, Paul W., Swartling, Fredrik J., Dlugosz, Andrzej A., Wong, Sunny Y.
Published in Cell reports (Cambridge) (03.05.2022)
Published in Cell reports (Cambridge) (03.05.2022)
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Journal Article
LGR5 promotes tumorigenicity and invasion of glioblastoma stem‐like cells and is a potential therapeutic target for a subset of glioblastoma patients
Xie, Yuan, Sundström, Anders, Maturi, Naga P, Tan, E‐Jean, Marinescu, Voichita D, Jarvius, Malin, Tirfing, Malin, Jin, Chuan, Chen, Lei, Essand, Magnus, Swartling, Fredrik J, Nelander, Sven, Jiang, Yiwen, Uhrbom, Lene
Published in JOURNAL OF PATHOLOGY (01.02.2019)
Published in JOURNAL OF PATHOLOGY (01.02.2019)
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Journal Article
Publication
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
Morgan, Daniel, Studham, Matthew, Tjärnberg, Andreas, Weishaupt, Holger, Swartling, Fredrik J., Nordling, Torbjörn E. M., Sonnhammer, Erik L. L.
Published in Scientific reports (25.08.2020)
Published in Scientific reports (25.08.2020)
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Journal Article
Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
Roy, Ananya, Attarha, Sanaz, Weishaupt, Holger, Edqvist, Per-Henrik, Swartling, Fredrik J., Bergqvist, Michael, Siebzehnrubl, Florian A., Smits, Anja, Pontén, Fredrik, Tchougounova, Elena
Published in Oncotarget (2017)
Published in Oncotarget (2017)
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Journal Article
miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma
Põlajeva, Jelena, Swartling, Fredrik J, Jiang, Yiwen, Singh, Umashankar, Pietras, Kristian, Uhrbom, Lene, Westermark, Bengt, Roswall, Pernilla
Published in BMC cancer (29.08.2012)
Published in BMC cancer (29.08.2012)
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Journal Article
Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity
Wallmann, Tatjana, Zhang, Xing-Mei, Wallerius, Majken, Bolin, Sara, Joly, Anne-Laure, Sobocki, Caroline, Leiss, Lina, Jiang, Yiwen, Bergh, Jonas, Holland, Eric C., Enger, Per Ø., Andersson, John, Swartling, Fredrik J., Miletic, Hrvoje, Uhrbom, Lene, Harris, Robert A., Rolny, Charlotte
Published in iScience (30.11.2018)
Published in iScience (30.11.2018)
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Journal Article
Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Published in Nature communications (02.11.2018)
Published in Nature communications (02.11.2018)
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Journal Article
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
Johansson, Patrik, Krona, Cecilia, Kundu, Soumi, Doroszko, Milena, Baskaran, Sathishkumar, Schmidt, Linnéa, Vinel, Claire, Almstedt, Elin, Elgendy, Ramy, Elfineh, Ludmila, Gallant, Caroline, Lundsten, Sara, Ferrer Gago, Fernando J., Hakkarainen, Aleksi, Sipilä, Petra, Häggblad, Maria, Martens, Ulf, Lundgren, Bo, Frigault, Melanie M., Lane, David P., Swartling, Fredrik J., Uhrbom, Lene, Nestor, Marika, Marino, Silvia, Nelander, Sven
Published in Cell reports (Cambridge) (14.07.2020)
Published in Cell reports (Cambridge) (14.07.2020)
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Journal Article
Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
Roy, Ananya, Libard, Sylwia, Weishaupt, Holger, Gustavsson, Ida, Uhrbom, Lene, Hesselager, Göran, Swartling, Fredrik J., Pontén, Fredrik, Alafuzoff, Irina, Tchougounova, Elena
Published in Frontiers in oncology (02.06.2017)
Published in Frontiers in oncology (02.06.2017)
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Journal Article