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Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein–Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1)
Ghaffari, Siavash, Naderi Nabi, Farnoosh, Sugiyama, Michael G., Lee, Warren L.
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2018)
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Journal Article
Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation
Ramírez, Cristina M., Zhang, Xinbo, Bandyopadhyay, Chirosree, Rotllan, Noemi, Sugiyama, Michael G., Aryal, Binod, Liu, Xinran, He, Shun, Kraehling, Jan R., Ulrich, Victoria, Lin, Chin Sheng, Velazquez, Heino, Lasunción, Miguel A., Li, Guangxin, Suárez, Yajaira, Tellides, George, Swirski, Filip K., Lee, Warren L., Schwartz, Martin A., Sessa, William C., Fernández-Hernando, Carlos
Published in Circulation (New York, N.Y.) (16.07.2019)
Published in Circulation (New York, N.Y.) (16.07.2019)
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Journal Article
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling
Sugiyama, Michael G., Brown, Aidan I., Vega-Lugo, Jesus, Borges, Jazlyn P., Scott, Andrew M., Jaqaman, Khuloud, Fairn, Gregory D., Antonescu, Costin N.
Published in Nature communications (09.05.2023)
Published in Nature communications (09.05.2023)
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Journal Article
Lung Ultrasound and Microbubbles Enhance Aminoglycoside Efficacy and Delivery to the Lung in Escherichia coli –induced Pneumonia and Acute Respiratory Distress Syndrome
Sugiyama, Michael G., Mintsopoulos, Victoria, Raheel, Hira, Goldenberg, Neil M., Batt, Jane E., Brochard, Laurent, Kuebler, Wolfgang M., Leong-Poi, Howard, Karshafian, Raffi, Lee, Warren L.
Published in American journal of respiratory and critical care medicine (01.08.2018)
Published in American journal of respiratory and critical care medicine (01.08.2018)
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Journal Article
The Ileal Lipid Binding Protein Is Required for Efficient Absorption and Transport of Bile Acids in the Distal Portion of the Murine Small Intestine
Praslickova, Dana, Torchia, Enrique C., Sugiyama, Michael G., Magrane, Elijah J., Zwicker, Brittnee L., Kolodzieyski, Lev, Agellon, Luis B.
Published in PloS one (10.12.2012)
Published in PloS one (10.12.2012)
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Journal Article
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation
Jones, Sylwia, King, Peter J., Antonescu, Costin N., Sugiyama, Michael G., Bhamra, Amandeep, Surinova, Silvia, Angelopoulos, Nicos, Kragh, Michael, Pedersen, Mikkel W., Hartley, John A., Futter, Clare E., Hochhauser, Daniel
Published in Scientific reports (20.01.2020)
Published in Scientific reports (20.01.2020)
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Journal Article
Loss of tumor suppressor TMEM127 drives RET-mediated transformation through disrupted membrane dynamics
Walker, Timothy J, Reyes-Alvarez, Eduardo, Hyndman, Brandy D, Sugiyama, Michael G, Oliveira, Larissa CB, Rekab, Aisha N, Crupi, Mathieu JF, Cabral-Dias, Rebecca, Guo, Qianjin, Dahia, Patricia LM, Richardson, Douglas S, Antonescu, Costin N, Mulligan, Lois M
Published in eLife (30.04.2024)
Published in eLife (30.04.2024)
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Journal Article
The Tie2-agonist Vasculotide rescues mice from influenza virus infection
Sugiyama, Michael G., Armstrong, Susan M., Wang, Changsen, Hwang, David, Leong-Poi, Howard, Advani, Andrew, Advani, Suzanne, Zhang, Haibo, Szaszi, Katalin, Tabuchi, Arata, Kuebler, Wolfgang M., Van Slyke, Paul, Dumont, Dan J., Lee, Warren L.
Published in Scientific reports (05.06.2015)
Published in Scientific reports (05.06.2015)
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Journal Article
Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury
Sugiyama, Michael G., Gamage, Asela, Zyla, Roman, Armstrong, Susan M., Advani, Suzanne, Advani, Andrew, Wang, Changsen, Lee, Warren L.
Published in Journal of virology (15.02.2016)
Published in Journal of virology (15.02.2016)
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Journal Article
A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis
Armstrong, Susan M., Sugiyama, Michael G., Fung, Karen Y.Y., Gao, Yizhuo, Wang, Changsen, Levy, Andrew S., Azizi, Paymon, Roufaiel, Mark, Zhu, Su-Ning, Neculai, Dante, Yin, Charles, Bolz, Steffen-Sebastian, Seidah, Nabil G., Cybulsky, Myron I., Heit, Bryan, Lee, Warren L.
Published in Cardiovascular research (01.11.2015)
Published in Cardiovascular research (01.11.2015)
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Journal Article
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling
Cabral-Dias, Rebecca, Lucarelli, Stefanie, Zak, Karolina, Rahmani, Sadia, Judge, Gurjeet, Abousawan, John, DiGiovanni, Laura F., Vural, Dafne, Anderson, Karen E., Sugiyama, Michael G., Genc, Gizem, Hong, Wanjin, Botelho, Roberto J., Fairn, Gregory D., Kim, Peter K., Antonescu, Costin N.
Published in The Journal of cell biology (04.04.2022)
Published in The Journal of cell biology (04.04.2022)
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Journal Article
Quantitative modeling of EGF receptor ligand discrimination via internalization proofreading
Leblanc, Jaleesa A, Sugiyama, Michael G, Antonescu, Costin N, Brown, Aidan I
Published in Physical biology (01.09.2023)
Published in Physical biology (01.09.2023)
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Journal Article
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease
Sugiyama, Michael G., Cui, Haotian, Redka, Dar’ya S., Karimzadeh, Mehran, Rujas, Edurne, Maan, Hassaan, Hayat, Sikander, Cheung, Kyle, Misra, Rahul, McPhee, Joseph B., Viirre, Russell D., Haller, Andrew, Botelho, Roberto J., Karshafian, Raffi, Sabatinos, Sarah A., Fairn, Gregory D., Madani Tonekaboni, Seyed Ali, Windemuth, Andreas, Julien, Jean-Philippe, Shahani, Vijay, MacKinnon, Stephen S., Wang, Bo, Antonescu, Costin N.
Published in Scientific reports (02.12.2021)
Published in Scientific reports (02.12.2021)
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Journal Article
Influenza-Induced Priming and Leak of Human Lung Microvascular Endothelium upon Exposure to Staphylococcus aureus
Wang, Changsen, Armstrong, Susan M., Sugiyama, Michael G., Tabuchi, Arata, Krauszman, Adrienn, Kuebler, Wolfgang M., Mullen, Brendan, Advani, Suzanne, Advani, Andrew, Lee, Warren L.
Published in American journal of respiratory cell and molecular biology (01.10.2015)
Published in American journal of respiratory cell and molecular biology (01.10.2015)
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Journal Article
Visualization of Sex-Dimorphic Changes in the Intestinal Transcriptome of Fabp2 Gene-Ablated Mice
Sugiyama, Michael G., Hobson, Luc, Agellon, Al B., Agellon, Luis B.
Published in Lifestyle genomics (01.01.2012)
Published in Lifestyle genomics (01.01.2012)
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Journal Article
Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics
Walker, Timothy J, Reyes-Alvarez, Eduardo, Hyndman, Brandy D, Sugiyama, Michael G, Oliveira, Larissa C B, Rekab, Aisha N, Crupi, Mathieu J F, Cabral-Dias, Rebecca, Guo, Qianjin, Dahia, Patricia L M, Richardson, Douglas S, Antonescu, Costin N, Mulligan, Lois M
Published in bioRxiv (03.04.2024)
Published in bioRxiv (03.04.2024)
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Journal Article
Paper
Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells
Kraehling, Jan R., Chidlow, John H., Rajagopal, Chitra, Sugiyama, Michael G., Fowler, Joseph W., Lee, Monica Y., Zhang, Xinbo, Ramírez, Cristina M., Park, Eon Joo, Tao, Bo, Chen, Keyang, Kuruvilla, Leena, Larriveé, Bruno, Folta-Stogniew, Ewa, Ola, Roxana, Rotllan, Noemi, Zhou, Wenping, Nagle, Michael W., Herz, Joachim, Williams, Kevin Jon, Eichmann, Anne, Lee, Warren L., Fernández-Hernando, Carlos, Sessa, William C.
Published in Nature communications (21.11.2016)
Published in Nature communications (21.11.2016)
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Journal Article