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Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
Palmqvist, Sebastian, Schöll, Michael, Strandberg, Olof, Mattsson, Niklas, Stomrud, Erik, Zetterberg, Henrik, Blennow, Kaj, Landau, Susan, Jagust, William, Hansson, Oskar
Published in Nature communications (31.10.2017)
Published in Nature communications (31.10.2017)
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Journal Article
Longitudinal plasma p-tau217 is increased in early stages of Alzheimer’s disease
Mattsson-Carlgren, Niklas, Janelidze, Shorena, Palmqvist, Sebastian, Cullen, Nicholas, Svenningsson, Anna L, Strandberg, Olof, Mengel, David, Walsh, Dominic M, Stomrud, Erik, Dage, Jeffrey L, Hansson, Oskar
Published in Brain (London, England : 1878) (05.12.2020)
Published in Brain (London, England : 1878) (05.12.2020)
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Journal Article
Diagnostic Performance of RO948 F 18 Tau Positron Emission Tomography in the Differentiation of Alzheimer Disease From Other Neurodegenerative Disorders
Leuzy, Antoine, Smith, Ruben, Ossenkoppele, Rik, Santillo, Alexander, Borroni, Edilio, Klein, Gregory, Ohlsson, Tomas, Jögi, Jonas, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Strandberg, Olof, Stomrud, Erik, Hansson, Oskar
Published in Archives of neurology (Chicago) (01.08.2020)
Published in Archives of neurology (Chicago) (01.08.2020)
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Journal Article
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring
Ashton, Nicholas J., Janelidze, Shorena, Mattsson-Carlgren, Niklas, Binette, Alexa Pichet, Strandberg, Olof, Brum, Wagner S., Karikari, Thomas K., González-Ortiz, Fernándo, Di Molfetta, Guglielmo, Meda, Francisco J., Jonaitis, Erin M., Koscik, Rebecca Langhough, Cody, Karly, Betthauser, Tobey J., Li, Yan, Vanmechelen, Eugeen, Palmqvist, Sebastian, Stomrud, Erik, Bateman, Randall J., Zetterberg, Henrik, Johnson, Sterling C., Blennow, Kaj, Hansson, Oskar
Published in Nature medicine (01.12.2022)
Published in Nature medicine (01.12.2022)
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Journal Article
Head-to-head comparison of tau positron emission tomography tracers [18F]flortaucipir and [18F]RO948
Smith, Ruben, Schöll, Michael, Leuzy, Antoine, Jögi, Jonas, Ohlsson, Tomas, Strandberg, Olof, Hansson, Oskar
Published in European journal of nuclear medicine and molecular imaging (01.02.2020)
Published in European journal of nuclear medicine and molecular imaging (01.02.2020)
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Journal Article
Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline
Ossenkoppele, Rik, Pichet Binette, Alexa, Groot, Colin, Smith, Ruben, Strandberg, Olof, Palmqvist, Sebastian, Stomrud, Erik, Tideman, Pontus, Ohlsson, Tomas, Jögi, Jonas, Johnson, Keith, Sperling, Reisa, Dore, Vincent, Masters, Colin L., Rowe, Christopher, Visser, Denise, van Berckel, Bart N. M., van der Flier, Wiesje M., Baker, Suzanne, Jagust, William J., Wiste, Heather J., Petersen, Ronald C., Jack, Clifford R., Hansson, Oskar
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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Journal Article
Distinct 18F-AV-1451 tau PET retention patterns in early- and late-onset Alzheimer’s disease
Schöll, Michael, Ossenkoppele, Rik, Strandberg, Olof, Palmqvist, Sebastian, Jögi, Jonas, Ohlsson, Tomas, Smith, Ruben, Hansson, Oskar
Published in Brain (London, England : 1878) (01.09.2017)
Published in Brain (London, England : 1878) (01.09.2017)
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Journal Article
Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders
Palmqvist, Sebastian, Janelidze, Shorena, Quiroz, Yakeel T, Zetterberg, Henrik, Lopera, Francisco, Stomrud, Erik, Su, Yi, Chen, Yinghua, Serrano, Geidy E, Leuzy, Antoine, Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Villegas, Andres, Sepulveda-Falla, Diego, Chai, Xiyun, Proctor, Nicholas K, Beach, Thomas G, Blennow, Kaj, Dage, Jeffrey L, Reiman, Eric M, Hansson, Oskar
Published in JAMA : the journal of the American Medical Association (25.08.2020)
Published in JAMA : the journal of the American Medical Association (25.08.2020)
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Journal Article
A multicenter comparison of [18F]flortaucipir, [18F]RO948, and [18F]MK6240 tau PET tracers to detect a common target ROI for differential diagnosis
Leuzy, Antoine, Pascoal, Tharick A., Strandberg, Olof, Insel, Philip, Smith, Ruben, Mattsson-Carlgren, Niklas, Benedet, Andréa L., Cho, Hannah, Lyoo, Chul H., La Joie, Renaud, Rabinovici, Gil D., Ossenkoppele, Rik, Rosa-Neto, Pedro, Hansson, Oskar
Published in European journal of nuclear medicine and molecular imaging (01.07.2021)
Published in European journal of nuclear medicine and molecular imaging (01.07.2021)
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Journal Article
Compensating for choroid plexus based off-target signal in the hippocampus using 18F-flortaucipir PET
Pawlik, Daria, Leuzy, Antoine, Strandberg, Olof, Smith, Ruben
Published in NeuroImage (Orlando, Fla.) (01.11.2020)
Published in NeuroImage (Orlando, Fla.) (01.11.2020)
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Journal Article
Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease
Leuzy, Antoine, Smith, Ruben, Cullen, Nicholas C, Strandberg, Olof, Vogel, Jacob W, Binette, Alexa Pichet, Borroni, Edilio, Janelidze, Shorena, Ohlsson, Tomas, Jögi, Jonas, Ossenkoppele, Rik, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Klein, Gregory, Stomrud, Erik, Hansson, Oskar
Published in Archives of neurology (Chicago) (01.02.2022)
Published in Archives of neurology (Chicago) (01.02.2022)
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Journal Article
Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders
Ossenkoppele, Rik, Rabinovici, Gil D, Smith, Ruben, Cho, Hanna, Schöll, Michael, Strandberg, Olof, Palmqvist, Sebastian, Mattsson, Niklas, Janelidze, Shorena, Santillo, Alexander, Ohlsson, Tomas, Jögi, Jonas, Tsai, Richard, La Joie, Renaud, Kramer, Joel, Boxer, Adam L, Gorno-Tempini, Maria L, Miller, Bruce L, Choi, Jae Y, Ryu, Young H, Lyoo, Chul H, Hansson, Oskar
Published in JAMA : the journal of the American Medical Association (18.09.2018)
Published in JAMA : the journal of the American Medical Association (18.09.2018)
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Journal Article
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
Horie, Kanta, Salvadó, Gemma, Barthélemy, Nicolas R., Janelidze, Shorena, Li, Yan, He, Yingxin, Saef, Benjamin, Chen, Charles D., Jiang, Hong, Strandberg, Olof, Pichet Binette, Alexa, Palmqvist, Sebastian, Sato, Chihiro, Sachdev, Pallavi, Koyama, Akihiko, Gordon, Brian A., Benzinger, Tammie L. S., Holtzman, David M., Morris, John C., Mattsson-Carlgren, Niklas, Stomrud, Erik, Ossenkoppele, Rik, Schindler, Suzanne E., Hansson, Oskar, Bateman, Randall J.
Published in Nature medicine (01.08.2023)
Published in Nature medicine (01.08.2023)
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Journal Article
Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading
Frontzkowski, Lukas, Ewers, Michael, Brendel, Matthias, Biel, Davina, Ossenkoppele, Rik, Hager, Paul, Steward, Anna, Dewenter, Anna, Römer, Sebastian, Rubinski, Anna, Buerger, Katharina, Janowitz, Daniel, Binette, Alexa Pichet, Smith, Ruben, Strandberg, Olof, Carlgren, Niklas Mattsson, Dichgans, Martin, Hansson, Oskar, Franzmeier, Nicolai
Published in Nature communications (20.08.2022)
Published in Nature communications (20.08.2022)
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Journal Article
Tau PET correlates with different Alzheimer’s disease‐related features compared to CSF and plasma p‐tau biomarkers
Ossenkoppele, Rik, Reimand, Juhan, Smith, Ruben, Leuzy, Antoine, Strandberg, Olof, Palmqvist, Sebastian, Stomrud, Erik, Zetterberg, Henrik, Scheltens, Philip, Dage, Jeffrey L, Bouwman, Femke, Blennow, Kaj, Mattsson‐Carlgren, Niklas, Janelidze, Shorena, Hansson, Oskar
Published in EMBO molecular medicine (09.08.2021)
Published in EMBO molecular medicine (09.08.2021)
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Journal Article
18F‐AV‐1451 and CSF T‐tau and P‐tau as biomarkers in Alzheimer's disease
Mattsson, Niklas, Schöll, Michael, Strandberg, Olof, Smith, Ruben, Palmqvist, Sebastian, Insel, Philip S, Hägerström, Douglas, Ohlsson, Tomas, Zetterberg, Henrik, Jögi, Jonas, Blennow, Kaj, Hansson, Oskar
Published in EMBO molecular medicine (01.09.2017)
Published in EMBO molecular medicine (01.09.2017)
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Journal Article
Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease
Pereira, Joana B., Hall, Sara, Jalakas, Mattis, Grothe, Michel J., Strandberg, Olof, Stomrud, Erik, Westman, Eric, van Westen, Danielle, Hansson, Oskar
Published in Neurobiology of disease (01.06.2020)
Published in Neurobiology of disease (01.06.2020)
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Journal Article
Lewy body pathology exacerbates brain hypometabolism and cognitive decline in Alzheimer’s disease
Collij, Lyduine E., Mastenbroek, Sophie E., Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Janelidze, Shorena, Palmqvist, Sebastian, Ossenkoppele, Rik, Hansson, Oskar
Published in Nature communications (14.09.2024)
Published in Nature communications (14.09.2024)
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Journal Article
Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer’s disease
Franzmeier, Nicolai, Dewenter, Anna, Frontzkowski, Lukas, Dichgans, Martin, Rubinski, Anna, Neitzel, Julia, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Buerger, Katharina, Duering, Marco, Hansson, Oskar, Ewers, Michael
Published in Science advances (27.11.2020)
Published in Science advances (27.11.2020)
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Journal Article