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The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature
Inman, Gareth J., Wang, Jun, Nagano, Ai, Alexandrov, Ludmil B., Purdie, Karin J., Taylor, Richard G., Sherwood, Victoria, Thomson, Jason, Hogan, Sarah, Spender, Lindsay C., South, Andrew P., Stratton, Michael, Chelala, Claude, Harwood, Catherine A., Proby, Charlotte M., Leigh, Irene M.
Published in Nature communications (10.09.2018)
Published in Nature communications (10.09.2018)
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Journal Article
In vivo topical gene therapy for recessive dystrophic epidermolysis bullosa: a phase 1 and 2 trial
Gurevich, Irina, Agarwal, Pooja, Zhang, PeiPei, Dolorito, John A., Oliver, Stacie, Liu, Henry, Reitze, Nicholas, Sarma, Nikhil, Bagci, Isin Sinem, Sridhar, Kunju, Kakarla, Visesha, Yenamandra, Vamsi K., O’Malley, Mark, Prisco, Marco, Tufa, Sara F., Keene, Douglas R., South, Andrew P., Krishnan, Suma M., Marinkovich, M. Peter
Published in Nature medicine (01.04.2022)
Published in Nature medicine (01.04.2022)
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Journal Article
Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis
Zhang, Zhuzhen, Zi, Zhenzhen, Lee, Eunice E, Zhao, Jiawei, Contreras, Diana C, South, Andrew P, Abel, E Dale, Chong, Benjamin F, Vandergriff, Travis, Hosler, Gregory A, Scherer, Philipp E, Mettlen, Marcel, Rathmell, Jeffrey C, DeBerardinis, Ralph J, Wang, Richard C
Published in Nature medicine (01.05.2018)
Published in Nature medicine (01.05.2018)
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Journal Article
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
South, Andrew P., Purdie, Karin J., Watt, Stephen A., Haldenby, Sam, den Breems, Nicoline Y., Dimon, Michelle, Arron, Sarah T., Kluk, Michael J., Aster, Jon C., McHugh, Angela, Xue, Dylan J., Dayal, Jasbani H.S., Robinson, Kim S., Hasan Rizvi, S.M., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M.
Published in Journal of investigative dermatology (01.10.2014)
Published in Journal of investigative dermatology (01.10.2014)
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Journal Article
Innate sensing of microbial products promotes wound-induced skin cancer
Hoste, Esther, Arwert, Esther N., Lal, Rohit, South, Andrew P., Salas-Alanis, Julio C., Murrell, Dedee F., Donati, Giacomo, Watt, Fiona M.
Published in Nature communications (09.01.2015)
Published in Nature communications (09.01.2015)
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Journal Article
Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa
Atanasova, Velina S., Jiang, Qiujie, Prisco, Marco, Gruber, Christina, Piñón Hofbauer, Josefina, Chen, Mei, Has, Cristina, Bruckner-Tuderman, Leena, McGrath, John A., Uitto, Jouni, South, Andrew P.
Published in Journal of investigative dermatology (01.09.2017)
Published in Journal of investigative dermatology (01.09.2017)
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Journal Article
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
Wang, Nicholas J, Sanborn, Zachary, Arnett, Kelly L, Bayston, Laura J, Liao, Wilson, Proby, Charlotte M, Leigh, Irene M, Collisson, Eric A, Gordon, Patricia B, Jakkula, Lakshmi, Pennypacker, Sally, Zou, Yong, Sharma, Mimansa, North, Jeffrey P, Vemula, Swapna S, Mauro, Theodora M, Neuhaus, Isaac M, LeBoit, Philip E, Hur, Joe S, Park, Kyunghee, Huh, Nam, Kwok, Pui-Yan, Arron, Sarah T, Massion, Pierre P, Bale, Allen E, Haussler, David, Cleaver, James E, Gray, Joe W, Spellman, Paul T, South, Andrew P, Aster, Jon C, Blacklow, Stephen C, Cho, Raymond J
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2011)
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Journal Article
Metaanalysis of the prevalence of intrauterine fetal death in gastroschisis
South, Andrew P., Stutey, Kevin M., Meinzen-Derr, Jareen
Published in American journal of obstetrics and gynecology (01.08.2013)
Published in American journal of obstetrics and gynecology (01.08.2013)
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Journal Article
Tumor microenvironment governs the prognostic landscape of immunotherapy for head and neck squamous cell carcinoma: A computational model-guided analysis
Bhattacharya, Priyan, Linnenbach, Alban, South, Andrew P., Martinez-Outschoorn, Ubaldo, Curry, Joseph M., Johnson, Jennifer M., Harshyne, Larry A., Mahoney, Mỹ G., Luginbuhl, Adam J., Vadigepalli, Rajanikanth
Published in PLoS computational biology (03.06.2025)
Published in PLoS computational biology (03.06.2025)
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Journal Article
Mutations in GRHL2 Result in an Autosomal-Recessive Ectodermal Dysplasia Syndrome
Petrof, Gabriela, Nanda, Arti, Howden, Jake, Takeichi, Takuya, McMillan, James R., Aristodemou, Sophia, Ozoemena, Linda, Liu, Lu, South, Andrew P., Pourreyron, Celine, Dafou, Dimitra, Proudfoot, Laura E., Al-Ajmi, Hejab, Akiyama, Masashi, McLean, W.H. Irwin, Simpson, Michael A., Parsons, Maddy, McGrath, John A.
Published in American journal of human genetics (04.09.2014)
Published in American journal of human genetics (04.09.2014)
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Journal Article
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
Cammareri, Patrizia, Rose, Aidan M., Vincent, David F., Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A., Athineos, Dimitris, Coates, Philip J., McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H. S., Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C., Sapkota, Gopal P., Purdie, Karin J., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P., Sansom, Owen J., Inman, Gareth J.
Published in Nature communications (25.08.2016)
Published in Nature communications (25.08.2016)
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Journal Article
Mathematical modeling of cancer cell invasion of tissue: biological insight from mathematical analysis and computational simulation
Andasari, Vivi, Gerisch, Alf, Lolas, Georgios, South, Andrew P., Chaplain, Mark A. J.
Published in Journal of mathematical biology (01.07.2011)
Published in Journal of mathematical biology (01.07.2011)
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Journal Article
Mutations in AQP5, Encoding a Water-Channel Protein, Cause Autosomal-Dominant Diffuse Nonepidermolytic Palmoplantar Keratoderma
Blaydon, Diana C., Lind, Lisbet K., Plagnol, Vincent, Linton, Kenneth J., Smith, Francis J.D., Wilson, Neil J., McLean, W.H. Irwin, Munro, Colin S., South, Andrew P., Leigh, Irene M., O’Toole, Edel A., Lundström, Anita, Kelsell, David P.
Published in American journal of human genetics (08.08.2013)
Published in American journal of human genetics (08.08.2013)
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Journal Article
Maintenance of chronicity signatures in fibroblasts isolated from recessive dystrophic epidermolysis bullosa chronic wound dressings under culture conditions
De Gregorio, Cristian, Catalán, Evelyng, Garrido, Gabriel, Morandé, Pilar, Bennett, Jimena Castillo, Muñoz, Catalina, Cofré, Glenda, Huang, Ya-Lin, Cuadra, Bárbara, Murgas, Paola, Calvo, Margarita, Altermatt, Fernando, Yubero, María Joao, Palisson, Francis, South, Andrew P., Ezquer, Marcelo, Fuentes, Ignacia
Published in Biological research (10.05.2023)
Published in Biological research (10.05.2023)
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Journal Article
RHBDF2 Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome
Blaydon, Diana C., Etheridge, Sarah L., Risk, Janet M., Hennies, Hans-Christian, Gay, Laura J., Carroll, Rebecca, Plagnol, Vincent, McRonald, Fiona E., Stevens, Howard P., Spurr, Nigel K., Bishop, D. Timothy, Ellis, Anthony, Jankowski, Janusz, Field, John K., Leigh, Irene M., South, Andrew P., Kelsell, David P.
Published in American journal of human genetics (10.02.2012)
Published in American journal of human genetics (10.02.2012)
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Journal Article
Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility
McGrath, John A., Stone, Kristina L., Begum, Rumena, Simpson, Michael A., Dopping-Hepenstal, Patricia J., Liu, Lu, McMillan, James R., South, Andrew P., Pourreyron, Celine, McLean, W.H. Irwin, Martinez, Anna E., Mellerio, Jemima E., Parsons, Maddy
Published in American journal of human genetics (07.12.2012)
Published in American journal of human genetics (07.12.2012)
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Journal Article
Antiviral drugs prolong survival in murine recessive dystrophic epidermolysis bullosa
Tartaglia, Grace, Fuentes, Ignacia, Patel, Neil, Varughese, Abigail, Israel, Lauren E, Park, Pyung Hun, Alexander, Michael H, Poojan, Shiv, Cao, Qingqing, Solomon, Brenda, Padron, Zachary M, Dyer, Jonathan A, Mellerio, Jemima E, McGrath, John A, Palisson, Francis, Salas-Alanis, Julio, Han, Lin, South, Andrew P
Published in EMBO molecular medicine (15.04.2024)
Published in EMBO molecular medicine (15.04.2024)
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Journal Article
Altered extracellular matrix correlates with an immunosuppressive tumor microenvironment and disease progression in younger adults with oral cavity squamous cell carcinoma
Estephan, Leonard E., Kumar, Gaurav, Stewart, Matthew, Banoub, Raphael, Linnenbach, Alban, Harshyne, Larry A., Martinez-Outschoorn, Ubaldo E., Mahoney, My G., Curry, Joseph M., Johnson, Jennifer, South, Andrew P., Luginbuhl, Adam J.
Published in Frontiers in oncology (18.06.2024)
Published in Frontiers in oncology (18.06.2024)
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Journal Article
Wnt5a Is Strongly Expressed at the Leading Edge in Non-Melanoma Skin Cancer, Forming Active Gradients, while Canonical Wnt Signalling Is Repressed
Pourreyron, Celine, Reilly, Louise, Proby, Charlotte, Panteleyev, Andrey, Fleming, Colin, McLean, Kathleen, South, Andrew P., Foerster, John
Published in PloS one (22.02.2012)
Published in PloS one (22.02.2012)
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Journal Article