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A Role for Noncoding Variation in Schizophrenia
Roussos, Panos, Mitchell, Amanda C., Voloudakis, Georgios, Fullard, John F., Pothula, Venu M., Tsang, Jonathan, Stahl, Eli A., Georgakopoulos, Anastasios, Ruderfer, Douglas M., Charney, Alexander, Okada, Yukinori, Siminovitch, Katherine A., Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Plenge, Robert M., Raychaudhuri, Soumya, Fromer, Menachem, Purcell, Shaun M., Brennand, Kristen J., Robakis, Nikolaos K., Schadt, Eric E., Akbarian, Schahram, Sklar, Pamela
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
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Journal Article
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A, Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A, Bae, Sang-Cheol, Plenge, Robert M, Gregersen, Peter K, de Bakker, Paul I W
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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Journal Article
Ultra-high-resolution mapping of myelin and g-ratio in a panel of Mbp enhancer-edited mouse strains using microstructural MRI
Grouza, Vladimir, Bagheri, Hooman, Liu, Hanwen, Tuznik, Marius, Wu, Zhe, Robinson, Nicole, Siminovitch, Katherine A., Peterson, Alan C., Rudko, David A.
Published in NeuroImage (Orlando, Fla.) (15.10.2024)
Published in NeuroImage (Orlando, Fla.) (15.10.2024)
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Journal Article
Pervasive Sharing of Genetic Effects in Autoimmune Disease
Cotsapas, Chris, Voight, Benjamin F., Rossin, Elizabeth, Lage, Kasper, Neale, Benjamin M., Wallace, Chris, Abecasis, Gonçalo R., Barrett, Jeffrey C., Behrens, Timothy, Cho, Judy, De Jager, Philip L., Elder, James T., Graham, Robert R., Gregersen, Peter, Klareskog, Lars, Siminovitch, Katherine A., van Heel, David A., Wijmenga, Cisca, Worthington, Jane, Todd, John A., Hafler, David A., Rich, Stephen S., Daly, Mark J.
Published in PLoS genetics (01.08.2011)
Published in PLoS genetics (01.08.2011)
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Journal Article
Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis
Diogo, Dorothée, Kurreeman, Fina, Stahl, Eli A., Liao, Katherine P., Gupta, Namrata, Greenberg, Jeffrey D., Rivas, Manuel A., Hickey, Brendan, Flannick, Jason, Thomson, Brian, Guiducci, Candace, Ripke, Stephan, Adzhubey, Ivan, Barton, Anne, Kremer, Joel M., Alfredsson, Lars, Sunyaev, Shamil, Martin, Javier, Zhernakova, Alexandra, Bowes, John, Eyre, Steve, Siminovitch, Katherine A., Gregersen, Peter K., Worthington, Jane, Klareskog, Lars, Padyukov, Leonid, Raychaudhuri, Soumya, Plenge, Robert M.
Published in American journal of human genetics (10.01.2013)
Published in American journal of human genetics (10.01.2013)
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Journal Article
Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
Han, Younghun, Byun, Jinyoung, Zhu, Catherine, Sun, Ryan, Roh, Julia Y., Cordell, Heather J., Lee, Hyun-Sung, Shaw, Vikram R., Kang, Sung Wook, Razjouyan, Javad, Cooley, Matthew A., Hassan, Manal M., Siminovitch, Katherine A., Folseraas, Trine, Ellinghaus, David, Bergquist, Annika, Rushbrook, Simon M., Franke, Andre, Karlsen, Tom H., Lazaridis, Konstantinos N., McGlynn, Katherine A., Roberts, Lewis R., Amos, Christopher I.
Published in Nature communications (24.02.2023)
Published in Nature communications (24.02.2023)
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Journal Article
Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis
Mkhikian, Haik, Grigorian, Ani, Li, Carey F., Chen, Hung-Lin, Newton, Barbara, Zhou, Raymond W., Beeton, Christine, Torossian, Sevan, Tatarian, Gevork Grikor, Lee, Sung-Uk, Lau, Ken, Walker, Erin, Siminovitch, Katherine A., Chandy, K. George, Yu, Zhaoxia, Dennis, James W., Demetriou, Michael
Published in Nature communications (31.05.2011)
Published in Nature communications (31.05.2011)
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Journal Article
Nonreceptor Protein-Tyrosine Phosphatases in Immune Cell Signaling
Pao, Lily I, Badour, Karen, Siminovitch, Katherine A, Neel, Benjamin G
Published in Annual Review of Immunology (01.01.2007)
Published in Annual Review of Immunology (01.01.2007)
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Journal Article
The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease
Pochini, Lorena, Scalise, Mariafrancesca, Galluccio, Michele, Pani, Giovambattista, Siminovitch, Katherine A., Indiveri, Cesare
Published in Biochimica et biophysica acta (01.03.2012)
Published in Biochimica et biophysica acta (01.03.2012)
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Journal Article
RFC1 80G>A Is a Genetic Determinant of Methotrexate Efficacy in Rheumatoid Arthritis: A Human Genome Epidemiologic Review and Meta‐Analysis of Observational Studies
Kung, Tabitha N., Dennis, Jessica, Ma, YiQing, Xie, Gang, Bykerk, Vivian, Pope, Janet, Thorne, Carter, Keystone, Edward, Siminovitch, Katherine A., Gagnon, France
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2014)
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Journal Article
Genetics in PBC: What Do the “Risk Genes” Teach Us?
Hirschfield, Gideon M., Siminovitch, Katherine A.
Published in Clinical reviews in allergy & immunology (01.06.2015)
Published in Clinical reviews in allergy & immunology (01.06.2015)
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Journal Article
Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J., Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L., Siminovitch, Katherine A., Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K., Worthington, Jane, Gupta, Namrata, Clemons, Paul A., Stahl, Eli, Tolliday, Nicola, Plenge, Robert M.
Published in PLoS genetics (01.05.2013)
Published in PLoS genetics (01.05.2013)
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Journal Article
The mDial Formin Is Required for Neutrophil Polarization, Migration, and Activation of the LARG/RhoA/ROCK Signaling Axis during Chemotaxis
Shi, Yongquan, Zhang, Jinyi, Mullin, Michael, Dong, Baoxia, Alberts, Arthur S, Siminovitch, Katherine A
Published in The Journal of immunology (1950) (15.03.2009)
Published in The Journal of immunology (1950) (15.03.2009)
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Journal Article
Monoclonal Antibodies for the Treatment of Hypercholesterolemia: Targeting PCSK9
Alkindi, Manal, Siminovitch, Katherine A., Gupta, Milan, Genest, Jacques
Published in Canadian journal of cardiology (01.12.2016)
Published in Canadian journal of cardiology (01.12.2016)
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Journal Article
T Cell Responses in Mammalian Diaphanous-related Formin mDia1 Knock-out Mice
Eisenmann, Kathryn M., West, Richard A., Hildebrand, Dagmar, Kitchen, Susan M., Peng, Jun, Sigler, Robert, Zhang, Jinyi, Siminovitch, Katherine A., Alberts, Arthur S.
Published in The Journal of biological chemistry (24.08.2007)
Published in The Journal of biological chemistry (24.08.2007)
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Journal Article
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
Rioux, John D., Daly, Mark J., Silverberg, Mark S., Lindblad, Kerstin, Steinhart, Hillary, Cohen, Zane, Delmonte, Terrye, Kocher, Kerry, Miller, Katie, Guschwan, Sheila, Kulbokas, Edward J., O'Leary, Sinead, Winchester, Ellen, Dewar, Ken, Green, Todd, Stone, Valerie, Chow, Christine, Cohen, Albert, Langelier, Diane, Lapointe, Gilles, Gaudet, Daniel, Faith, Janet, Branco, Nancy, Bull, Shelley B., McLeod, Robin S., Griffiths, Anne M., Bitton, Alain, Greenberg, Gordon R., Lander, Eric S., Siminovitch, Katherine A., Hudson, Thomas J.
Published in Nature genetics (01.10.2001)
Published in Nature genetics (01.10.2001)
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Journal Article
N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination
Jin, Fuzi, Dong, Baoxia, Georgiou, John, Jiang, Qiuhong, Zhang, Jinyi, Bharioke, Arjun, Qiu, Frank, Lommel, Silvia, Feltri, M. Laura, Wrabetz, Lawrence, Roder, John C., Eyer, Joel, Chen, Xiequn, Peterson, Alan C., Siminovitch, Katherine A.
Published in Development (Cambridge) (01.04.2011)
Published in Development (Cambridge) (01.04.2011)
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Journal Article
Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization
Dong, Baoxia, Zhang, Steven S., Gao, Wen, Su, Haichun, Chen, Jun, Jin, Fuzi, Bhargava, Ajay, Chen, Xiequn, Jorgensen, Lars, Alberts, Arthur S., Zhang, Jinyi, Siminovitch, Katherine A.
Published in PloS one (18.11.2013)
Published in PloS one (18.11.2013)
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Journal Article