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Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia
Janelidze, Shorena, Mattsson, Niklas, Palmqvist, Sebastian, Smith, Ruben, Beach, Thomas G., Serrano, Geidy E., Chai, Xiyun, Proctor, Nicholas K., Eichenlaub, Udo, Zetterberg, Henrik, Blennow, Kaj, Reiman, Eric M., Stomrud, Erik, Dage, Jeffrey L., Hansson, Oskar
Published in Nature medicine (01.03.2020)
Published in Nature medicine (01.03.2020)
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Journal Article
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
Haney, Michael S., Pálovics, Róbert, Munson, Christy Nicole, Long, Chris, Johansson, Patrik K., Yip, Oscar, Dong, Wentao, Rawat, Eshaan, West, Elizabeth, Schlachetzki, Johannes C. M., Tsai, Andy, Guldner, Ian Hunter, Lamichhane, Bhawika S., Smith, Amanda, Schaum, Nicholas, Calcuttawala, Kruti, Shin, Andrew, Wang, Yung-Hua, Wang, Chengzhong, Koutsodendris, Nicole, Serrano, Geidy E., Beach, Thomas G., Reiman, Eric M., Glass, Christopher K., Abu-Remaileh, Monther, Enejder, Annika, Huang, Yadong, Wyss-Coray, Tony
Published in Nature (London) (04.04.2024)
Published in Nature (London) (04.04.2024)
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Journal Article
Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders
Palmqvist, Sebastian, Janelidze, Shorena, Quiroz, Yakeel T, Zetterberg, Henrik, Lopera, Francisco, Stomrud, Erik, Su, Yi, Chen, Yinghua, Serrano, Geidy E, Leuzy, Antoine, Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Villegas, Andres, Sepulveda-Falla, Diego, Chai, Xiyun, Proctor, Nicholas K, Beach, Thomas G, Blennow, Kaj, Dage, Jeffrey L, Reiman, Eric M, Hansson, Oskar
Published in JAMA : the journal of the American Medical Association (25.08.2020)
Published in JAMA : the journal of the American Medical Association (25.08.2020)
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Journal Article
Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation
Srinivasan, Karpagam, Friedman, Brad A., Etxeberria, Ainhoa, Huntley, Melanie A., van der Brug, Marcel P., Foreman, Oded, Paw, Jonathan S., Modrusan, Zora, Beach, Thomas G., Serrano, Geidy E., Hansen, David V.
Published in Cell reports (Cambridge) (30.06.2020)
Published in Cell reports (Cambridge) (30.06.2020)
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Journal Article
Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau
Mattsson‐Carlgren, Niklas, Janelidze, Shorena, Bateman, Randall J, Smith, Ruben, Stomrud, Erik, Serrano, Geidy E, Reiman, Eric M, Palmqvist, Sebastian, Dage, Jeffrey L, Beach, Thomas G, Hansson, Oskar
Published in EMBO molecular medicine (07.06.2021)
Published in EMBO molecular medicine (07.06.2021)
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Journal Article
Dopaminergic Retinal Cell Loss and Visual Dysfunction in Parkinson Disease
Ortuño‐Lizarán, Isabel, Sánchez‐Sáez, Xavier, Lax, Pedro, Serrano, Geidy E., Beach, Thomas G., Adler, Charles H., Cuenca, Nicolás
Published in Annals of neurology (01.11.2020)
Published in Annals of neurology (01.11.2020)
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Journal Article
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
Salvadó, Gemma, Ossenkoppele, Rik, Ashton, Nicholas J, Beach, Thomas G, Serrano, Geidy E, Reiman, Eric M, Zetterberg, Henrik, Mattsson‐Carlgren, Niklas, Janelidze, Shorena, Blennow, Kaj, Hansson, Oskar
Published in EMBO molecular medicine (08.05.2023)
Published in EMBO molecular medicine (08.05.2023)
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Journal Article
Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Dong, Xianjun, Bai, Yunfei, Liao, Zhixiang, Gritsch, David, Liu, Xiaoli, Wang, Tao, Borges-Monroy, Rebeca, Ehrlich, Alyssa, Serrano, Geidy E., Feany, Mel B., Beach, Thomas G., Scherzer, Clemens R.
Published in Nature communications (18.09.2023)
Published in Nature communications (18.09.2023)
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Journal Article
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age
Wingo, Aliza P., Dammer, Eric B., Breen, Michael S., Logsdon, Benjamin A., Duong, Duc M., Troncosco, Juan C., Thambisetty, Madhav, Beach, Thomas G., Serrano, Geidy E., Reiman, Eric M., Caselli, Richard J., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Wingo, Thomas S.
Published in Nature communications (08.04.2019)
Published in Nature communications (08.04.2019)
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Journal Article
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Minhas, Paras S., Jones, Jeffrey R., Latif-Hernandez, Amira, Sugiura, Yuki, Durairaj, Aarooran S., Wang, Qian, Mhatre, Siddhita D., Uenaka, Takeshi, Crapser, Joshua, Conley, Travis, Ennerfelt, Hannah, Jung, Yoo Jin, Liu, Ling, Prasad, Praveena, Jenkins, Brenita C., Ay, Yeonglong Albert, Matrongolo, Matthew, Goodman, Ryan, Newmeyer, Traci, Heard, Kelly, Kang, Austin, Wilson, Edward N., Yang, Tao, Ullian, Erik M., Serrano, Geidy E., Beach, Thomas G., Wernig, Marius, Rabinowitz, Joshua D., Suematsu, Makoto, Longo, Frank M., McReynolds, Melanie R., Gage, Fred H., Andreasson, Katrin I.
Published in Science (23.08.2024)
Published in Science (23.08.2024)
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Journal Article
Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease
Hall, Sara, Orrù, Christina D., Serrano, Geidy E., Galasko, Douglas, Hughson, Andrew G., Groveman, Bradley R., Adler, Charles H., Beach, Thomas G., Caughey, Byron, Hansson, Oskar
Published in Acta neuropathologica communications (22.06.2022)
Published in Acta neuropathologica communications (22.06.2022)
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Journal Article
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology
Mastenbroek, Sophie E., Vogel, Jacob W., Collij, Lyduine E., Serrano, Geidy E., Tremblay, Cécilia, Young, Alexandra L., Arce, Richard A., Shill, Holly A., Driver-Dunckley, Erika D., Mehta, Shyamal H., Belden, Christine M., Atri, Alireza, Choudhury, Parichita, Barkhof, Frederik, Adler, Charles H., Ossenkoppele, Rik, Beach, Thomas G., Hansson, Oskar
Published in Nature communications (15.06.2024)
Published in Nature communications (15.06.2024)
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Journal Article
Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer’s disease
Noor, Fatima, Aslam, Sidra, Piras, Ignazio S., Tremblay, Cecilia, Beach, Thomas G., Serrano, Geidy E.
Published in Frontiers in immunology (26.06.2025)
Published in Frontiers in immunology (26.06.2025)
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Journal Article
Impaired hepatic amyloid-beta degradation in Alzheimer’s disease
Maarouf, Chera L., Walker, Jessica E., Sue, Lucia I., Dugger, Brittany N., Beach, Thomas G., Serrano, Geidy E.
Published in PloS one (07.09.2018)
Published in PloS one (07.09.2018)
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Journal Article
Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging
Adler, Charles H, Beach, Thomas G, Zhang, Nan, Shill, Holly A, Driver-Dunckley, Erika, Caviness, John N, Mehta, Shyamal H, Sabbagh, Marwan N, Serrano, Geidy E, Sue, Lucia I, Belden, Christine M, Powell, Jessica, Jacobson, Sandra A, Zamrini, Edward, Shprecher, David, Davis, Kathryn J, Dugger, Brittany N, Hentz, Joseph G
Published in Journal of neuropathology and experimental neurology (01.10.2019)
Published in Journal of neuropathology and experimental neurology (01.10.2019)
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Journal Article
Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levels
Wennström, Malin, Janelidze, Shorena, Nilsson, K. Peter R., Serrano, Geidy E., Beach, Thomas G., Dage, Jeffrey L., Hansson, Oskar
Published in Acta neuropathologica communications (06.01.2022)
Published in Acta neuropathologica communications (06.01.2022)
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Journal Article
Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
Mastenbroek, Sophie E., Collij, Lyduine E., Vogel, Jacob W., Caldera, Serena, Serrano, Geidy E., Adler, Charles H., Vargiu, Claudia Marina, Palmqvist, Sebastian, Barkhof, Frederik, Parchi, Piero, Beach, Thomas G., Ossenkoppele, Rik, Hansson, Oskar
Published in Nature communications (05.08.2025)
Published in Nature communications (05.08.2025)
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Journal Article
Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
Wang, Qi, Antone, Jerry, Alsop, Eric, Reiman, Rebecca, Funk, Cory, Bendl, Jaroslav, Dudley, Joel T., Liang, Winnie S., Karr, Timothy L., Roussos, Panos, Bennett, David A., De Jager, Philip L., Serrano, Geidy E., Beach, Thomas G., Van Keuren-Jensen, Kendall, Mastroeni, Diego, Reiman, Eric M., Readhead, Benjamin P.
Published in Nature communications (10.07.2024)
Published in Nature communications (10.07.2024)
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Journal Article
Effect of olfactory bulb pathology on olfactory function in normal aging
Tremblay, Cécilia, Serrano, Geidy E., Intorcia, Anthony J., Sue, Lucia I., Wilson, Jeffrey R., Adler, Charles H., Shill, Holly A., Driver‐Dunckley, Erika, Mehta, Shyamal H., Beach, Thomas G.
Published in Brain pathology (Zurich, Switzerland) (01.09.2022)
Published in Brain pathology (Zurich, Switzerland) (01.09.2022)
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Journal Article