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Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection
Henao‐Restrepo, Julián, López‐Murillo, Carolina, Valderrama‐Carmona, Pablo, Orozco‐Santa, Natalia, Gomez, Johana, Gutiérrez‐Vargas, Johanna, Moraga, Renato, Toledo, Jorge, Littau, Jessica Lisa, Härtel, Steffen, Arboleda‐Velásquez, Joseph F., Sepulveda‐Falla, Diego, Lopera, Francisco, Cardona‐Gómez, Gloria Patricia, Villegas, Andrés, Posada‐Duque, Rafael
Published in Brain pathology (Zurich, Switzerland) (01.03.2023)
Published in Brain pathology (Zurich, Switzerland) (01.03.2023)
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Journal Article
Distinct microglia profile in Creutzfeldt–Jakob disease and Alzheimer's disease is independent of disease kinetics
Krbot, Katarina, Hermann, Peter, Skorić, Magdalena Krbot, Zerr, Inga, Sepulveda‐Falla, Diego, Goebel, Stefan, Matschke, Jakob, Krasemann, Susanne, Glatzel, Markus
Published in Neuropathology (01.12.2018)
Published in Neuropathology (01.12.2018)
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Journal Article
Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease
Sepulveda-Falla, Diego, Matschke, Jakob, Bernreuther, Christian, Hagel, Christian, Puig, Berta, Villegas, Andres, Garcia, Gloria, Zea, Julian, Gomez-Mancilla, Baltazar, Ferrer, Isidre, Lopera, Francisco, Glatzel, Markus
Published in Brain pathology (Zurich, Switzerland) (01.07.2011)
Published in Brain pathology (Zurich, Switzerland) (01.07.2011)
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Journal Article
Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders
Palmqvist, Sebastian, Janelidze, Shorena, Quiroz, Yakeel T, Zetterberg, Henrik, Lopera, Francisco, Stomrud, Erik, Su, Yi, Chen, Yinghua, Serrano, Geidy E, Leuzy, Antoine, Mattsson-Carlgren, Niklas, Strandberg, Olof, Smith, Ruben, Villegas, Andres, Sepulveda-Falla, Diego, Chai, Xiyun, Proctor, Nicholas K, Beach, Thomas G, Blennow, Kaj, Dage, Jeffrey L, Reiman, Eric M, Hansson, Oskar
Published in JAMA : the journal of the American Medical Association (25.08.2020)
Published in JAMA : the journal of the American Medical Association (25.08.2020)
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Journal Article
The Nairobi Declaration—Reducing the burden of dementia in low‐ and middle‐income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs
Maestre, Gladys, Carrillo, Maria, Kalaria, Raj, Acosta, Daisy, Adams, Larry, Adoukonou, Thierry, Akinwande, Kazeem, Akinyemi, Joshua, Akinyemi, Rufus, Akpa, Onoja, Alladi, Suvarna, Allegri, Ricardo, Arizaga, Raul, Arshad, Faheem, Arulogun, Oyedunni, Babalola, David, Baiyewu, Olusegun, Bak, Thomas, Bellaj, Tarek, Boshe, Judith, Brayne, Carol, Brodie-Mends, David, Brown, Richard, Cahn, Jennifer, Cyrille, Nkouonlack, De Silva, Ranil, De Silva, Rohan, Dreyer, Anna Jane, Ellajosyula, Ratnavalli, Farombi, Temitope, Fongang, Bernard, Forner, Stefania, Friedland, Rob, Garza, Noe, Gbessemehlan, Antoine, Georgiou, Eliza Eleni-Zacharoula, Gouider, Riadh, Govia, Ishtar, Grinberg, Lea, Guerchet, Maëlenn, Hogervorst, Eef, Hornberger, Michael, Ibanez, Agustin, Ihara, Masafumi, Ismail, Ozama, Issac, Thomas, Jönsson, Linus, Kaputu, Celestin, Karanja, Wambui, Karungi, Jackline, Tshala-Katumbay, Desire, Leroi, Iracema, Livingston, Gill, Manes, Facundo, Mbakile-Mahlanza, Lingani, Mena, Pedro, Miller, Bruce, Millogo, Athanase, Musyimi, Christine, Mutiso, Victoria, Nakasujja, Noeline, Ndetei, David, Nightingale, Sam, Njamnshi, Alfred K, Novotni, Gabriela, Nyamayaro, Primrose, Ogeng'o, Julius, Ogunniyi, Adesola, Okada De Oliveira, Maira, Okubadejo, Njideka, Orrell, Martin, Orunmuyi, Akintunde, Paddick, Stella, A Pericak-Vance, Margaret, Pirtosek, Zvezdan, Raman, Rema, Rosselli, Monica, Deepa, Roy, Roy, Upal, Sano, Mary, Sarfo, Fred, Satizabal, Claudia L, Sepulveda-Falla, Diego, Seshadri, Sudha, Sexton, Claire, Skoog, Ingmar, St George-Hyslop, Peter, Suemoto, Claudia, Tanner, Jeremy, Thapa, Prekshya, Toure, Kamadore, Udeh-Momoh, Chinedu, Valcour, Victor, Vance, Jeffery, Varghese, Mathew, Walker, Richard, Sebastian, Walsh, Whitehead Gay, Patrice, Zewde, Yared, African Dementia Consortium
Published in Alzheimer's & Dementia (01.03.2023)
Published in Alzheimer's & Dementia (01.03.2023)
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Journal Article
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
Rasmussen, Jay, Mahler, Jasmin, Beschorner, Natalie, Kaeser, Stephan A., Häsler, Lisa M., Baumann, Frank, Nyström, Sofie, Portelius, Erik, Blennow, Kaj, Lashley, Tammaryn, Fox, Nick C., Sepulveda-Falla, Diego, Glatzel, Markus, Oblak, Adrian L., Ghetti, Bernardino, Nilsson, K. Peter R., Hammarström, Per, Staufenbiel, Matthias, Walker, Lary C., Jucker, Mathias
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
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Journal Article
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
Sepulveda-Falla, Diego, Sanchez, Justin S., Almeida, Maria Camila, Boassa, Daniela, Acosta-Uribe, Juliana, Vila-Castelar, Clara, Ramirez-Gomez, Liliana, Baena, Ana, Aguillon, David, Villalba-Moreno, Nelson David, Littau, Jessica Lisa, Villegas, Andres, Beach, Thomas G., White, Charles L., Ellisman, Mark, Krasemann, Susanne, Glatzel, Markus, Johnson, Keith A., Sperling, Reisa A., Reiman, Eric M., Arboleda-Velasquez, Joseph F., Kosik, Kenneth S., Lopera, Francisco, Quiroz, Yakeel T.
Published in Acta neuropathologica (01.09.2022)
Published in Acta neuropathologica (01.09.2022)
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Journal Article
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease
Sepulveda-Falla, Diego, Chavez-Gutierrez, Lucia, Portelius, Erik, Vélez, Jorge I., Dujardin, Simon, Barrera-Ocampo, Alvaro, Dinkel, Felix, Hagel, Christian, Puig, Berta, Mastronardi, Claudio, Lopera, Francisco, Hyman, Bradley T., Blennow, Kaj, Arcos-Burgos, Mauricio, de Strooper, Bart, Glatzel, Markus
Published in Acta neuropathologica (01.02.2021)
Published in Acta neuropathologica (01.02.2021)
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Journal Article
Genetic modifiers of cognitive decline in PSEN1 E280A Alzheimer's disease
Sepulveda‐Falla, Diego, Vélez, Jorge I., Acosta‐Baena, Natalia, Baena, Ana, Moreno, Sonia, Krasemann, Susanne, Lopera, Francisco, Mastronardi, Claudio A., Arcos‐Burgos, Mauricio
Published in Alzheimer's & dementia (01.04.2024)
Published in Alzheimer's & dementia (01.04.2024)
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Journal Article
Losing sleep over mitochondria: a new player in the pathophysiology of fatal familial insomnia
Glatzel, Markus, Sepulveda‐Falla, Diego
Published in Brain pathology (Zurich, Switzerland) (01.01.2017)
Published in Brain pathology (Zurich, Switzerland) (01.01.2017)
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Journal Article
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia
Hartmann, Kristin, Sepulveda-Falla, Diego, Rose, Indigo V. L., Madore, Charlotte, Muth, Christiane, Matschke, Jakob, Butovsky, Oleg, Liddelow, Shane, Glatzel, Markus, Krasemann, Susanne
Published in Acta neuropathologica communications (22.05.2019)
Published in Acta neuropathologica communications (22.05.2019)
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Journal Article
Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis
Sepulveda-Falla, Diego, Barrera-Ocampo, Alvaro, Hagel, Christian, Korwitz, Anne, Vinueza-Veloz, Maria Fernanda, Zhou, Kuikui, Schonewille, Martijn, Zhou, Haibo, Velazquez-Perez, Luis, Rodriguez-Labrada, Roberto, Villegas, Andres, Ferrer, Isidro, Lopera, Francisco, Langer, Thomas, De Zeeuw, Chris I., Glatzel, Markus
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Journal Article
APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation
Marino, Claudia, Perez‐Corredor, Paula, O'Hare, Michael, Heuer, Annie, Chmielewska, Natalia, Gordon, Harper, Chandrahas, Anita S., Gonzalez‐Buendia, Lucia, Delgado‐Tirado, Santiago, Doan, Tri H., Vanderleest, Timothy E., Arevalo‐Alquichire, Said, Obar, Robert A., Ortiz‐Cordero, Carolina, Villegas, Andres, Sepulveda‐Falla, Diego, Kim, Leo A., Lopera, Francisco, Mahley, Robert, Huang, Yadong, Quiroz, Yakeel T., Arboleda‐Velasquez, Joseph F.
Published in Alzheimer's & dementia (01.02.2024)
Published in Alzheimer's & dementia (01.02.2024)
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Journal Article
Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease
Littau, Jessica Lisa, Velilla, Lina, Hase, Yoshiki, Villalba‐Moreno, Nelson David, Hagel, Christian, Drexler, Dagmar, Osorio Restrepo, Santiago, Villegas, Andres, Lopera, Francisco, Vargas, Sergio, Glatzel, Markus, Krasemann, Susanne, Quiroz, Yakeel T., Arboleda‐Velasquez, Joseph F., Kalaria, Rajesh, Sepulveda‐Falla, Diego
Published in Brain pathology (Zurich, Switzerland) (01.11.2022)
Published in Brain pathology (Zurich, Switzerland) (01.11.2022)
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Journal Article
Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study
Acosta-Baena, Natalia, Sepulveda-Falla, Diego, Lopera-Gómez, Carlos Mario, Jaramillo-Elorza, Mario César, Moreno, Sonia, Aguirre-Acevedo, Daniel Camilo, Saldarriaga, Amanda, Lopera, Francisco
Published in Lancet neurology (01.03.2011)
Published in Lancet neurology (01.03.2011)
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Journal Article
Reactive Astrocytes Contribute to Alzheimer’s Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay
Wasilewski, David, Villalba-Moreno, Nelson David, Stange, Inke, Glatzel, Markus, Sepulveda-Falla, Diego, Krasemann, Susanne
Published in Frontiers in cellular neuroscience (21.01.2022)
Published in Frontiers in cellular neuroscience (21.01.2022)
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Journal Article
Neural Plasticity during Aging
Arcos-Burgos, Mauricio, Lopera, Francisco, Sepulveda-Falla, Diego, Mastronardi, Claudio
Published in Journal of neural transplantation & plasticity (01.01.2019)
Published in Journal of neural transplantation & plasticity (01.01.2019)
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Journal Article
Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis
Rojas-Charry, Liliana, Calero-Martinez, Sergio, Morganti, Claudia, Morciano, Giampaolo, Park, Kyungeun, Hagel, Christian, Marciniak, Stefan J., Glatzel, Markus, Pinton, Paolo, Sepulveda-Falla, Diego
Published in Scientific reports (15.04.2020)
Published in Scientific reports (15.04.2020)
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Journal Article