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Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase
Kumari, Manju, Schoiswohl, Gabriele, Chitraju, Chandramohan, Paar, Margret, Cornaciu, Irina, Rangrez, Ashraf Y., Wongsiriroj, Nuttaporn, Nagy, Harald M., Ivanova, Pavlina T., Scott, Sarah A., Knittelfelder, Oskar, Rechberger, Gerald N., Birner-Gruenberger, Ruth, Eder, Sandra, Brown, H. Alex, Haemmerle, Guenter, Oberer, Monika, Lass, Achim, Kershaw, Erin E., Zimmermann, Robert, Zechner, Rudolf
Published in Cell metabolism (02.05.2012)
Published in Cell metabolism (02.05.2012)
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Journal Article
FAM83B mediates EGFR- and RAS-driven oncogenic transformation
Cipriano, Rocky, Graham, James, Miskimen, Kristy L.S., Bryson, Benjamin L., Bruntz, Ronald C., Scott, Sarah A., Brown, H. Alex, Stark, George R., Jackson, Mark W.
Published in The Journal of clinical investigation (01.09.2012)
Published in The Journal of clinical investigation (01.09.2012)
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Journal Article
Multi-organ Abnormalities and mTORC1 Activation in Zebrafish Model of Multiple Acyl-CoA Dehydrogenase Deficiency
Kim, Seok-Hyung, Scott, Sarah A., Bennett, Michael J., Carson, Robert P., Fessel, Joshua, Brown, H. Alex, Ess, Kevin C.
Published in PLoS genetics (01.06.2013)
Published in PLoS genetics (01.06.2013)
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Journal Article
Design, Synthesis, and Biological Evaluation of Halogenated N-(2-(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: Discovery of an Isoform-Selective Small Molecule Phospholipase D2 Inhibitor
Lavieri, Robert R, Scott, Sarah A, Selvy, Paige E, Kim, Kwangho, Jadhav, Satyawan, Morrison, Ryan D, Daniels, J. Scott, Brown, H. Alex, Lindsley, Craig W
Published in Journal of medicinal chemistry (23.09.2010)
Published in Journal of medicinal chemistry (23.09.2010)
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Journal Article
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity
Lewis, Jana A., Scott, Sarah A., Lavieri, Robert, Buck, Jason R., Selvy, Paige E., Stoops, Sydney L., Armstrong, Michelle D., Brown, H. Alex, Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
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Journal Article
Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease
O’Keeffe, Fiona E., Scott, Sarah A., Tyers, Pam, O’Keeffe, Gerard W., Dalley, Jeffrey W., Zufferey, Romain, Caldwell, Maeve A.
Published in Brain (London, England : 1878) (01.03.2008)
Published in Brain (London, England : 1878) (01.03.2008)
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Journal Article
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness
Scott, Sarah A, Selvy, Paige E, Buck, Jason R, Cho, Hyekyung P, Criswell, Tracy L, Thomas, Ashley L, Armstrong, Michelle D, Arteaga, Carlos L, Lindsley, Craig W, Brown, H Alex
Published in Nature chemical biology (01.02.2009)
Published in Nature chemical biology (01.02.2009)
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Journal Article
Phospholipase D Facilitates Efficient Entry of Influenza Virus, Allowing Escape from Innate Immune Inhibition
Oguin, Thomas H., Sharma, Shalini, Stuart, Amanda D., Duan, Susu, Scott, Sarah A., Jones, Carrie K., Daniels, J. Scott, Lindsley, Craig W., Thomas, Paul G., Brown, H. Alex
Published in The Journal of biological chemistry (12.09.2014)
Published in The Journal of biological chemistry (12.09.2014)
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Journal Article
Chemical modulation of glycerolipid signaling and metabolic pathways
Scott, Sarah A., Mathews, Thomas P., Ivanova, Pavlina T., Lindsley, Craig W., Brown, H. Alex
Published in Biochimica et biophysica acta (01.08.2014)
Published in Biochimica et biophysica acta (01.08.2014)
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Journal Article
Development of Dual PLD1/2 and PLD2 Selective Inhibitors from a Common 1,3,8-Triazaspiro[4.5]decane Core: Discovery of ML298 and ML299 That Decrease Invasive Migration in U87-MG Glioblastoma Cells
O’Reilly, Matthew C, Scott, Sarah A, Brown, Kyle A, Oguin, Thomas H, Thomas, Paul G, Daniels, J. Scott, Morrison, Ryan, Brown, H. Alex, Lindsley, Craig W
Published in Journal of medicinal chemistry (28.03.2013)
Published in Journal of medicinal chemistry (28.03.2013)
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Journal Article
Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes
Scott, Sarah A, Spencer, Cierra T, O’Reilly, Matthew C, Brown, Kyle A, Lavieri, Robert R, Cho, Chul-Hee, Jung, Dai-Il, Larock, Richard C, Brown, H. Alex, Lindsley, Craig W
Published in ACS chemical biology (20.02.2015)
Published in ACS chemical biology (20.02.2015)
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Journal Article
Regulation of Phospholipase D Activity and Phosphatidic Acid Production after Purinergic (P2Y6) Receptor Stimulation
Scott, Sarah A., Xiang, Yun, Mathews, Thomas P., Cho, Hyekyung P., Myers, David S., Armstrong, Michelle D., Tallman, Keri A., O'Reilly, Matthew C., Lindsley, Craig W., Brown, H. Alex
Published in The Journal of biological chemistry (12.07.2013)
Published in The Journal of biological chemistry (12.07.2013)
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Journal Article
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity
Lavieri, Robert, Scott, Sarah A., Lewis, Jana A., Selvy, Paige E., Armstrong, Michelle D., Alex Brown, H., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Journal Article
Context-Dependent Substrate Recognition by Protein Farnesyltransferase
Hougland, James L, Lamphear, Corissa L, Scott, Sarah A, Gibbs, Richard A, Fierke, Carol A
Published in Biochemistry (Easton) (03.03.2009)
Published in Biochemistry (Easton) (03.03.2009)
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Journal Article
Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains
O'Reilly, Matthew C., Oguin III, Thomas H., Scott, Sarah A., Thomas, Paul G., Locuson, Charles W., Morrison, Ryan D., Daniels, J. Scott, Brown, H. Alex, Lindsley, Craig W.
Published in ChemMedChem (01.12.2014)
Published in ChemMedChem (01.12.2014)
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Journal Article
Back Cover: Discovery of a Highly Selective PLD2 Inhibitor (ML395): A New Probe with Improved Physiochemical Properties and Broad-Spectrum Antiviral Activity against Influenza Strains (ChemMedChem 12/2014)
O'Reilly, Matthew C., Oguin III, Thomas H., Scott, Sarah A., Thomas, Paul G., Locuson, Charles W., Morrison, Ryan D., Daniels, J. Scott, Brown, H. Alex, Lindsley, Craig W.
Published in ChemMedChem (01.12.2014)
Published in ChemMedChem (01.12.2014)
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Journal Article
Synthesis and evaluation of 3- and 7-substituted geranylgeranyl pyrophosphate analogs
Maynor, Michelle, Scott, Sarah A., Rickert, Emily L., Gibbs, Richard A.
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
Combinatorial Modulation of Protein Prenylation
Krzysiak, Amanda J, Rawat, Diwan S, Scott, Sarah A, Pais, June E, Handley, Misty, Harrison, Marietta L, Fierke, Carol A, Gibbs, Richard A
Published in ACS chemical biology (01.06.2007)
Published in ACS chemical biology (01.06.2007)
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Journal Article