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Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas
Canella, Alessandro, Welker, Alessandra M., Yoo, Ji Young, Xu, Jihong, Abas, Fazly S., Kesanakurti, Divya, Nagarajan, Prabakaran, Beattie, Christine E., Sulman, Erik P., Liu, Joseph, Gumin, Joy, Lang, Frederick F., Gurcan, Metin N., Kaur, Balveen, Sampath, Deepa, Puduvalli, Vinay K.
Published in Clinical cancer research (15.10.2017)
Published in Clinical cancer research (15.10.2017)
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Journal Article
LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia
Janani Ravikrishnan, Daisy Y. Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D. Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, KerryA Rogers, Adam S. Kittai, Seema A. Bhat, Mary C. Collins, Matthew S. Davids, Nitin Jain, William G. Wierda, Rosa Lapalombella, John C. Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P. Anthony, Jennifer A. Woyach, Deepa Sampath
Published in Haematologica (Roma) (01.01.2025)
Published in Haematologica (Roma) (01.01.2025)
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Journal Article
Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation
Mitchell, Shaneice, Zhang, Pu, Cannon, Matthew, Beaver, Larry, Lehman, Amy, Harrington, Bonnie, Sampath, Deepa, Byrd, John C., Lapalombella, Rosa
Published in Journal of hematology and oncology (29.06.2021)
Published in Journal of hematology and oncology (29.06.2021)
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Journal Article
Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia
Muhowski, Elizabeth M., Ravikrishnan, Janani, Gordon, Britten, Yu, Lianbo, Misra, Shrilekha, Walker, Brandi, Eathiraj, Sudharshan, Sampath, Deepa, Rogers, Kerry A., Byrd, John C., Woyach, Jennifer A.
Published in Journal of hematology and oncology (15.11.2022)
Published in Journal of hematology and oncology (15.11.2022)
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Journal Article
Comparison of clinical and molecular characteristics of patients with acute myeloid leukemia and either TP73 or TP53 mutations
Mims, Alice S., Kohlschmidt, Jessica, Eisfeld, Ann-Kathrin, Mrόzek, Krzysztof, Blachly, James S., Orwick, Shelley, Papaioannou, Dimitrios, Nicolet, Deedra, Sampath, Deepa, Stone, Richard M., Powell, Bayard L., Kolitz, Jonathan E., Byrd, John C., Bloomfield, Clara D.
Published in Leukemia (01.04.2021)
Published in Leukemia (01.04.2021)
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Journal Article
Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL
Chen, Timothy L., Harrington, Bonnie, Truxall, Jean, Wasmuth, Ronni, Prouty, Alexander, Sloan, Shelby, Lehman, Amy M., Sampath, Deepa, Orlemans, Eric, Baiocchi, Robert A., Alinari, Lapo, Byrd, John C., Woyach, Jennifer A., Hertlein, Erin
Published in Journal of hematology and oncology (24.02.2021)
Published in Journal of hematology and oncology (24.02.2021)
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Journal Article
Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation
Sampath, Deepa, Calin, George A., Puduvalli, Vinay K., Gopisetty, Gopal, Taccioli, Cristian, Liu, Chang-Gong, Ewald, Brett, Liu, Chaomei, Keating, Michael J., Plunkett, William
Published in Blood (16.04.2009)
Published in Blood (16.04.2009)
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Journal Article
DDDR-30. ENHANCED CHEMO AND RADIO-SENSITIZATION OF GLIOMAS BY HSP90 INHIBITION WITH JIN-001, A NOVEL BLOOD-BRAIN BARRIER PENETRANT HSP90 INHIBITOR
Xu, Jihong, Sugur, Harsha S, Sharma, Pratibha, Huo, Longfei, Dasgupta, Pushan, Chen, Xiaohua, Seah, Ethan, Sampath, Deepa, Puduvalli, Vinay K
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2024)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2024)
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Journal Article
TP53 Gain-of-Function Mutants Display Unique Transcriptional Profiles in Chronic Lymphocytic Leukemia
Williams, Charmelle D., Satpati, Suresh, Ravikrishnan, Janani, Slawin, Bailey, Diaz Rohena, Daisy Y., Thandapani, Palaniraja, Rogers, Kerry A., Bhat, Seema A., Rai, Kunal, Woyach, Jennifer A., Sampath, Deepa
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
Multiomic Single Cell Profiling Identifies Drivers of Progression in T-Cell Prolymphocytic Leukemia
Pawar, Vishakha Anand, Peris Cuesta, Arnau, Aradhya, Akanksha, Kettlun, Claudia, Iyer, Swaminathan P, Shukla, Sachet, Kadia, Tapan M., Vega, Francisco, Sampath, Deepa
Published in Blood (05.11.2024)
Published in Blood (05.11.2024)
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Journal Article
XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus
Ranganathan, Parvathi, Kashyap, Trinayan, Yu, Xueyan, Meng, Xiaomei, Lai, Tzung-Huei, McNeil, Betina, Bhatnagar, Bhavana, Shacham, Sharon, Kauffman, Michael, Dorrance, Adrienne M., Blum, William, Sampath, Deepa, Landesman, Yosef, Garzon, Ramiro
Published in Clinical cancer research (15.12.2016)
Published in Clinical cancer research (15.12.2016)
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Journal Article
Preclinical Evaluation of T-Cell Prolymphocytic Leukemia Demonstrates Heterogeneous BCL2-Family Dependency That May be Effectively Targeted with Small Molecule Inhibitors
Pawar, Vishakha Anand, Aradhya, Akanksha, Galvan, Daniel, Borthakur, Gautam, Iyer, Swami P., Kirschbaum, Mark, Blake, David, Kadia, Tapan M., Sampath, Deepa, Vega, Francisco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Venetoclax Synergizes with IMGN632, a Novel CD123-Targeting Antibody Conjugated to a DNA Alkylating Payload, By Suppressing DNA Damage Response and Potentiating Apoptosis in Acute Myeloid Leukemia in Vitro Models
Skwarska, Anna, Kuruvilla, Vinitha Mary, Zhang, Qi, Chaudhry, Sovira, Daver, Naval, Watkins, Krystal, Sloss, Callum Mortimer, Zweidler-McKay, Patrick A., Sampath, Deepa, Konopleva, Marina Y.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article